TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols ko04020 Calcium signaling pathway 8.73579504649726e-06 -11.6480816000317 176 12 0.114285714285714 105 7176 689560,50646,24681,691455,53949,24409,25302,25324,79247,309242,304592,29413 Ryr2,Ptk2b,Prkcg,Calml4,Chrm5,Grin2a,Chrna7,Htr4,Htr5b,Gna14,Orai2,Adra1d rno04020 Calcium signaling pathway 8.73579504649726e-06 -11.6480816000317 176 12 0.114285714285714 105 7176 29413,79247,309242,25324,304592,25302,24409,691455,53949,24681,50646,689560 Adra1d,Htr5b,Gna14,Htr4,Orai2,Chrna7,Grin2a,Calml4,Chrm5,Prkcg,Ptk2b,Ryr2 rno05033 Nicotine addiction 2.179409151362e-05 -10.7338716563902 40 6 0.0571428571428571 105 7176 29707,266767,50592,25302,116638,24409 Gabra5,Slc17a8,Gria1,Chrna7,Slc17a7,Grin2a ko05033 Nicotine addiction 2.179409151362e-05 -10.7338716563902 40 6 0.0571428571428571 105 7176 24409,25302,116638,50592,266767,29707 Grin2a,Chrna7,Slc17a7,Gria1,Slc17a8,Gabra5 rno05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 2.67820623648069e-05 -10.5277782092846 61 7 0.0666666666666667 105 7176 140727,315744,81008,689560,311144,25724,140729 Cacng6,Itga11,Itga7,Ryr2,Itga4,Itgb4,Cacng8 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 2.67820623648069e-05 -10.5277782092846 61 7 0.0666666666666667 105 7176 25724,140729,311144,81008,689560,315744,140727 Itgb4,Cacng8,Itga4,Itga7,Ryr2,Itga11,Cacng6 rno04713 Circadian entrainment 4.61904913639628e-05 -9.98273659569216 90 8 0.0761904761904762 105 7176 689560,24681,64455,25743,24409,691455,54286,50592 Ryr2,Prkcg,Rasd1,Kcnj6,Grin2a,Calml4,Prkg1,Gria1 ko04713 Circadian entrainment 4.61904913639628e-05 -9.98273659569216 90 8 0.0761904761904762 105 7176 24681,64455,689560,50592,25743,24409,691455,54286 Prkcg,Rasd1,Ryr2,Gria1,Kcnj6,Grin2a,Calml4,Prkg1 rno05410 Hypertrophic cardiomyopathy (HCM) 0.000112147780007346 -9.09569309204599 76 7 0.0666666666666667 105 7176 311144,140727,315744,81008,689560,25724,140729 Itga4,Cacng6,Itga11,Itga7,Ryr2,Itgb4,Cacng8 ko05410 Hypertrophic cardiomyopathy (HCM) 0.000112147780007346 -9.09569309204599 76 7 0.0666666666666667 105 7176 140727,315744,81008,689560,311144,140729,25724 Cacng6,Itga11,Itga7,Ryr2,Itga4,Cacng8,Itgb4 ko05414 Dilated cardiomyopathy 0.000143460341721008 -8.84945192527379 79 7 0.0666666666666667 105 7176 140729,25724,315744,140727,689560,81008,311144 Cacng8,Itgb4,Itga11,Cacng6,Ryr2,Itga7,Itga4 rno05414 Dilated cardiomyopathy 0.000143460341721008 -8.84945192527379 79 7 0.0666666666666667 105 7176 140729,25724,81008,689560,315744,140727,311144 Cacng8,Itgb4,Itga7,Ryr2,Itga11,Cacng6,Itga4 rno04080 Neuroactive ligand-receptor interaction 0.000235580258124846 -8.35345890373492 284 13 0.123809523809524 105 7176 66024,53949,24409,25302,50592,79247,25324,24406,84022,25153,29413,24473,29707 Npy2r,Chrm5,Grin2a,Chrna7,Gria1,Htr5b,Htr4,Grik4,Ghsr,Mas1,Adra1d,Htr1a,Gabra5 ko04080 Neuroactive ligand-receptor interaction 0.000235580258124846 -8.35345890373492 284 13 0.123809523809524 105 7176 66024,53949,24409,25302,50592,79247,25324,25153,84022,24406,29413,24473,29707 Npy2r,Chrm5,Grin2a,Chrna7,Gria1,Htr5b,Htr4,Mas1,Ghsr,Grik4,Adra1d,Htr1a,Gabra5 rno04723 Retrograde endocannabinoid signaling 0.000545650538627704 -7.51353182627526 98 7 0.0666666666666667 105 7176 29527,116638,25743,50592,266767,29707,24681 Ptgs2,Slc17a7,Kcnj6,Gria1,Slc17a8,Gabra5,Prkcg ko04723 Retrograde endocannabinoid signaling 0.000545650538627704 -7.51353182627526 98 7 0.0666666666666667 105 7176 24681,266767,50592,29707,116638,25743,29527 Prkcg,Slc17a8,Gria1,Gabra5,Slc17a7,Kcnj6,Ptgs2 rno04010 MAPK signaling pathway 0.000774538224525053 -7.16324354551623 242 11 0.104761904761905 105 7176 25443,140727,59109,310738,84488,140729,24681,293847,81737,24225,114513 Fgf10,Cacng6,Ntrk1,Ngf,Fgf13,Cacng8,Prkcg,Dusp9,Ntf3,Bdnf,Rasgrf2 ko04010 MAPK signaling pathway 0.000774538224525053 -7.16324354551623 242 11 0.104761904761905 105 7176 293847,24225,81737,114513,84488,310738,140729,24681,25443,140727,59109 Dusp9,Bdnf,Ntf3,Rasgrf2,Fgf13,Ngf,Cacng8,Prkcg,Fgf10,Cacng6,Ntrk1 ko04724 Glutamatergic synapse 0.000923809482171358 -6.98700469570852 107 7 0.0666666666666667 105 7176 266767,50592,24406,24681,29548,24409,116638 Slc17a8,Gria1,Grik4,Prkcg,Homer3,Grin2a,Slc17a7 rno04724 Glutamatergic synapse 0.000923809482171358 -6.98700469570852 107 7 0.0666666666666667 105 7176 24409,116638,29548,24406,24681,50592,266767 Grin2a,Slc17a7,Homer3,Grik4,Prkcg,Gria1,Slc17a8 rno04024 cAMP signaling pathway 0.0015937859654532 -6.44164298275329 187 9 0.0857142857142857 105 7176 24409,691455,24225,84022,25324,50592,689560,24473,295378 Grin2a,Calml4,Bdnf,Ghsr,Htr4,Gria1,Ryr2,Htr1a,Vav3 ko04024 cAMP signaling pathway 0.0015937859654532 -6.44164298275329 187 9 0.0857142857142857 105 7176 295378,24473,689560,50592,25324,84022,24225,691455,24409 Vav3,Htr1a,Ryr2,Gria1,Htr4,Ghsr,Bdnf,Calml4,Grin2a ko04512 ECM-receptor interaction 0.00189319162025316 -6.26949118617631 61 5 0.0476190476190476 105 7176 311144,81008,315744,445442,25724 Itga4,Itga7,Itga11,Thbs1,Itgb4 rno04512 ECM-receptor interaction 0.00189319162025316 -6.26949118617631 61 5 0.0476190476190476 105 7176 311144,315744,81008,445442,25724 Itga4,Itga11,Itga7,Thbs1,Itgb4 rno04810 Regulation of actin cytoskeleton 0.00220262724059618 -6.11810443083684 196 9 0.0857142857142857 105 7176 25443,295378,84488,360854,311144,53949,315744,81008,25724 Fgf10,Vav3,Fgf13,Arpc5,Itga4,Chrm5,Itga11,Itga7,Itgb4 ko04810 Regulation of actin cytoskeleton 0.00220262724059618 -6.11810443083684 196 9 0.0857142857142857 105 7176 25724,81008,315744,53949,311144,360854,84488,295378,25443 Itgb4,Itga7,Itga11,Chrm5,Itga4,Arpc5,Fgf13,Vav3,Fgf10 ko04672 Intestinal immune network for IgA production 0.00240169972895552 -6.03157857189982 39 4 0.0380952380952381 105 7176 294270,309622,294269,311144 RT1-Db1,RT1-Bb,RT1-Da,Itga4 rno04672 Intestinal immune network for IgA production 0.00240169972895552 -6.03157857189982 39 4 0.0380952380952381 105 7176 294269,311144,309622,294270 RT1-Da,Itga4,RT1-Bb,RT1-Db1 ko04360 Axon guidance 0.00247410011954603 -6.00187853713786 162 8 0.0761904761904762 105 7176 246331,65047,316539,84426,310207,171287,140933,315564 Nrp1,Slit1,Epha4,Wnt4,Sema5a,Epha7,Trpc5,Robo3 rno04360 Axon guidance 0.00247410011954603 -6.00187853713786 162 8 0.0761904761904762 105 7176 315564,140933,171287,310207,84426,65047,316539,246331 Robo3,Trpc5,Epha7,Sema5a,Wnt4,Slit1,Epha4,Nrp1 rno05140 Leishmaniasis 0.00268478642980616 -5.92015409615657 66 5 0.0476190476190476 105 7176 309622,294270,29527,294269,311144 RT1-Bb,RT1-Db1,Ptgs2,RT1-Da,Itga4 ko05140 Leishmaniasis 0.00268478642980616 -5.92015409615657 66 5 0.0476190476190476 105 7176 294270,309622,311144,294269,29527 RT1-Db1,RT1-Bb,Itga4,RT1-Da,Ptgs2 rno04014 Ras signaling pathway 0.00373295943812458 -5.59055394486694 212 9 0.0857142857142857 105 7176 25443,24681,310738,84488,360573,24409,691455,114513,85311 Fgf10,Prkcg,Ngf,Fgf13,Ksr1,Grin2a,Calml4,Rasgrf2,Pla1a rno04921 Oxytocin signaling pathway 0.00429729813191017 -5.44976879518806 140 7 0.0666666666666667 105 7176 691455,140727,29527,689560,25743,140729,24681 Calml4,Cacng6,Ptgs2,Ryr2,Kcnj6,Cacng8,Prkcg ko04921 Oxytocin signaling pathway 0.00429729813191017 -5.44976879518806 140 7 0.0666666666666667 105 7176 140729,24681,691455,140727,689560,29527,25743 Cacng8,Prkcg,Calml4,Cacng6,Ryr2,Ptgs2,Kcnj6 rno05310 Asthma 0.00554049246271187 -5.19567188998736 25 3 0.0285714285714286 105 7176 294269,294270,309622 RT1-Da,RT1-Db1,RT1-Bb ko05310 Asthma 0.00554049246271187 -5.19567188998736 25 3 0.0285714285714286 105 7176 294270,309622,294269 RT1-Db1,RT1-Bb,RT1-Da rno04726 Serotonergic synapse 0.00607301101313551 -5.10390074860951 113 6 0.0571428571428571 105 7176 24473,25743,29527,24681,79247,25324 Htr1a,Kcnj6,Ptgs2,Prkcg,Htr5b,Htr4 ko04015 Rap1 signaling pathway 0.00827077195715662 -4.79502743002756 198 8 0.0761904761904762 105 7176 24681,84488,310738,25443,114705,445442,24409,691455 Prkcg,Fgf13,Ngf,Fgf10,Rgs14,Thbs1,Grin2a,Calml4 rno04015 Rap1 signaling pathway 0.00827077195715662 -4.79502743002756 198 8 0.0761904761904762 105 7176 25443,84488,310738,24681,691455,24409,445442,114705 Fgf10,Fgf13,Ngf,Prkcg,Calml4,Grin2a,Thbs1,Rgs14 ko05152 Tuberculosis 0.00851809691689065 -4.76556232965307 159 7 0.0666666666666667 105 7176 24253,294270,309622,294269,360573,25599,691455 Cebpb,RT1-Db1,RT1-Bb,RT1-Da,Ksr1,Cd74,Calml4 rno05152 Tuberculosis 0.00851809691689065 -4.76556232965307 159 7 0.0666666666666667 105 7176 309622,294270,24253,25599,691455,360573,294269 RT1-Bb,RT1-Db1,Cebpb,Cd74,Calml4,Ksr1,RT1-Da rno04612 Antigen processing and presentation 0.00914305474167804 -4.69476073254029 88 5 0.0476190476190476 105 7176 294270,309622,294269,365527,25599 RT1-Db1,RT1-Bb,RT1-Da,RT1-M6-2,Cd74 ko04612 Antigen processing and presentation 0.00914305474167804 -4.69476073254029 88 5 0.0476190476190476 105 7176 294269,365527,25599,294270,309622 RT1-Da,RT1-M6-2,Cd74,RT1-Db1,RT1-Bb ko04916 Melanogenesis 0.0104875380487975 -4.55756757918133 91 5 0.0476190476190476 105 7176 24681,84426,100360552,303586,691455 Prkcg,Wnt4,Fzd7,Wnt9b,Calml4 rno04916 Melanogenesis 0.0104875380487975 -4.55756757918133 91 5 0.0476190476190476 105 7176 100360552,303586,84426,24681,691455 Fzd7,Wnt9b,Wnt4,Prkcg,Calml4 rno05332 Graft-versus-host disease 0.0112712361975976 -4.48550126771805 60 4 0.0380952380952381 105 7176 365527,294269,309622,294270 RT1-M6-2,RT1-Da,RT1-Bb,RT1-Db1 ko05332 Graft-versus-host disease 0.0112712361975976 -4.48550126771805 60 4 0.0380952380952381 105 7176 309622,294270,365527,294269 RT1-Bb,RT1-Db1,RT1-M6-2,RT1-Da ko04720 Long-term potentiation 0.0126116677711801 -4.37313287992506 62 4 0.0380952380952381 105 7176 24681,50592,24409,691455 Prkcg,Gria1,Grin2a,Calml4 ko05330 Allograft rejection 0.0126116677711801 -4.37313287992506 62 4 0.0380952380952381 105 7176 309622,294270,365527,294269 RT1-Bb,RT1-Db1,RT1-M6-2,RT1-Da rno05330 Allograft rejection 0.0126116677711801 -4.37313287992506 62 4 0.0380952380952381 105 7176 294269,365527,294270,309622 RT1-Da,RT1-M6-2,RT1-Db1,RT1-Bb rno04720 Long-term potentiation 0.0126116677711801 -4.37313287992506 62 4 0.0380952380952381 105 7176 50592,24681,691455,24409 Gria1,Prkcg,Calml4,Grin2a ko04510 Focal adhesion 0.0127939241226327 -4.35878489867112 172 7 0.0666666666666667 105 7176 25724,24681,445442,315744,81008,311144,295378 Itgb4,Prkcg,Thbs1,Itga11,Itga7,Itga4,Vav3 rno04510 Focal adhesion 0.0127939241226327 -4.35878489867112 172 7 0.0666666666666667 105 7176 445442,24681,25724,295378,311144,81008,315744 Thbs1,Prkcg,Itgb4,Vav3,Itga4,Itga7,Itga11 rno05031 Amphetamine addiction 0.0133185055977709 -4.31860081252347 63 4 0.0380952380952381 105 7176 50592,24681,691455,24409 Gria1,Prkcg,Calml4,Grin2a ko05031 Amphetamine addiction 0.0133185055977709 -4.31860081252347 63 4 0.0380952380952381 105 7176 24409,691455,24681,50592 Grin2a,Calml4,Prkcg,Gria1 rno_M00677 Wnt signaling 0.015317189820907 -4.17877956355109 36 3 0.0285714285714286 105 7176 303586,84426,100360552 Wnt9b,Wnt4,Fzd7 M00677 Wnt signaling 0.015317189820907 -4.17877956355109 36 3 0.0285714285714286 105 7176 100360552,84426,303586 Fzd7,Wnt4,Wnt9b rno05320 Autoimmune thyroid disease 0.0163966116842678 -4.11068057011548 67 4 0.0380952380952381 105 7176 294269,365527,294270,309622 RT1-Da,RT1-M6-2,RT1-Db1,RT1-Bb ko05320 Autoimmune thyroid disease 0.0163966116842678 -4.11068057011548 67 4 0.0380952380952381 105 7176 309622,294270,365527,294269 RT1-Bb,RT1-Db1,RT1-M6-2,RT1-Da rno04940 Type I diabetes mellitus 0.0180897305480527 -4.01241087476311 69 4 0.0380952380952381 105 7176 309622,294270,365527,294269 RT1-Bb,RT1-Db1,RT1-M6-2,RT1-Da ko04940 Type I diabetes mellitus 0.0180897305480527 -4.01241087476311 69 4 0.0380952380952381 105 7176 294269,365527,294270,309622 RT1-Da,RT1-M6-2,RT1-Db1,RT1-Bb rno04970 Salivary secretion 0.0208271671128977 -3.8714970332991 72 4 0.0380952380952381 105 7176 54286,691455,24681,29413 Prkg1,Calml4,Prkcg,Adra1d ko04970 Salivary secretion 0.0208271671128977 -3.8714970332991 72 4 0.0380952380952381 105 7176 24681,29413,691455,54286 Prkcg,Adra1d,Calml4,Prkg1 rno05322 Systemic lupus erythematosus 0.0238066288885655 -3.73779121235588 75 4 0.0380952380952381 105 7176 294269,24409,309622,294270 RT1-Da,Grin2a,RT1-Bb,RT1-Db1 ko05322 Systemic lupus erythematosus 0.0238066288885655 -3.73779121235588 75 4 0.0380952380952381 105 7176 309622,294270,24409,294269 RT1-Bb,RT1-Db1,Grin2a,RT1-Da ko04722 Neurotrophin signaling pathway 0.0272142309211734 -3.60401524686792 116 5 0.0476190476190476 105 7176 81737,24225,310738,59109,691455 Ntf3,Bdnf,Ngf,Ntrk1,Calml4 rno04722 Neurotrophin signaling pathway 0.0272142309211734 -3.60401524686792 116 5 0.0476190476190476 105 7176 81737,24225,310738,59109,691455 Ntf3,Bdnf,Ngf,Ntrk1,Calml4 rno05416 Viral myocarditis 0.0293219999029633 -3.52941719477541 80 4 0.0380952380952381 105 7176 294270,309622,294269,365527 RT1-Db1,RT1-Bb,RT1-Da,RT1-M6-2 rno05150 Staphylococcus aureus infection 0.029330590432943 -3.52912426551204 46 3 0.0285714285714286 105 7176 294269,309622,294270 RT1-Da,RT1-Bb,RT1-Db1 ko05150 Staphylococcus aureus infection 0.029330590432943 -3.52912426551204 46 3 0.0285714285714286 105 7176 294269,294270,309622 RT1-Da,RT1-Db1,RT1-Bb ko04640 Hematopoietic cell lineage 0.0317234260597919 -3.4506998785969 82 4 0.0380952380952381 105 7176 309622,294270,311144,294269 RT1-Bb,RT1-Db1,Itga4,RT1-Da rno04640 Hematopoietic cell lineage 0.0317234260597919 -3.4506998785969 82 4 0.0380952380952381 105 7176 294269,311144,294270,309622 RT1-Da,Itga4,RT1-Db1,RT1-Bb ko04728 Dopaminergic synapse 0.0348960877901047 -3.35538055376191 124 5 0.0476190476190476 105 7176 50592,24681,691455,25743,24409 Gria1,Prkcg,Calml4,Kcnj6,Grin2a rno04728 Dopaminergic synapse 0.0348960877901047 -3.35538055376191 124 5 0.0476190476190476 105 7176 24409,25743,691455,24681,50592 Grin2a,Kcnj6,Calml4,Prkcg,Gria1 rno04650 Natural killer cell mediated cytotoxicity 0.0368649029756978 -3.30049531942523 86 4 0.0380952380952381 105 7176 50646,24681,295378,64025 Ptk2b,Prkcg,Vav3,Cd244 ko04650 Natural killer cell mediated cytotoxicity 0.0368649029756978 -3.30049531942523 86 4 0.0380952380952381 105 7176 24681,50646,64025,295378 Prkcg,Ptk2b,Cd244,Vav3 M00056 O-glycan biosynthesis, mucin type core 0.0371689335324536 -3.29228198670542 21 2 0.019047619047619 105 7176 366061,288611 Galnt3,Galnt17 rno_M00056 O-glycan biosynthesis, mucin type core 0.0371689335324536 -3.29228198670542 21 2 0.019047619047619 105 7176 366061,288611 Galnt3,Galnt17 ko04145 Phagosome 0.0398952344338394 -3.22149839996796 172 6 0.0571428571428571 105 7176 445442,294270,309622,500377,294269,365527 Thbs1,RT1-Db1,RT1-Bb,Tuba8,RT1-Da,RT1-M6-2 rno04145 Phagosome 0.0398952344338394 -3.22149839996796 172 6 0.0571428571428571 105 7176 294269,365527,500377,445442,294270,309622 RT1-Da,RT1-M6-2,Tuba8,Thbs1,RT1-Db1,RT1-Bb rno05217 Basal cell carcinoma 0.0401178852966719 -3.21593302673243 52 3 0.0285714285714286 105 7176 303586,84426,100360552 Wnt9b,Wnt4,Fzd7 ko05217 Basal cell carcinoma 0.0401178852966719 -3.21593302673243 52 3 0.0285714285714286 105 7176 303586,84426,100360552 Wnt9b,Wnt4,Fzd7 rno05166 HTLV-I infection 0.0413338633358072 -3.18607317948692 267 8 0.0761904761904762 105 7176 365527,294270,303586,100360552,309622,294269,246331,84426 RT1-M6-2,RT1-Db1,Wnt9b,Fzd7,RT1-Bb,RT1-Da,Nrp1,Wnt4 ko05166 HTLV-I infection 0.0413338633358072 -3.18607317948692 267 8 0.0761904761904762 105 7176 84426,294269,246331,294270,303586,309622,100360552,365527 Wnt4,RT1-Da,Nrp1,RT1-Db1,Wnt9b,RT1-Bb,Fzd7,RT1-M6-2 M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 0.0432630988864863 -3.14045522703099 3 1 0.00952380952380952 105 7176 29221 Arg1 rno_M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 0.0432630988864863 -3.14045522703099 3 1 0.00952380952380952 105 7176 29221 Arg1 ko00515 Mannose type O-glycan biosynthesis 0.04394530602977 -3.12480946306282 23 2 0.019047619047619 105 7176 117108,64544 B3gat1,B3gat2 ko04392 Hippo signaling pathway -multiple species 0.04394530602977 -3.12480946306282 23 2 0.019047619047619 105 7176 310341,305922 Fat4,Lats2 rno04392 Hippo signaling pathway -multiple species 0.04394530602977 -3.12480946306282 23 2 0.019047619047619 105 7176 310341,305922 Fat4,Lats2 rno00515 Mannose type O-glycan biosynthesis 0.04394530602977 -3.12480946306282 23 2 0.019047619047619 105 7176 64544,117108 B3gat2,B3gat1 ko04730 Long-term depression 0.0461657473586913 -3.07551715502925 55 3 0.0285714285714286 105 7176 50592,24681,54286 Gria1,Prkcg,Prkg1 rno04730 Long-term depression 0.0461657473586913 -3.07551715502925 55 3 0.0285714285714286 105 7176 54286,24681,50592 Prkg1,Prkcg,Gria1 rno05321 Inflammatory bowel disease (IBD) 0.0482765687386642 -3.03080895531435 56 3 0.0285714285714286 105 7176 294270,309622,294269 RT1-Db1,RT1-Bb,RT1-Da ko05321 Inflammatory bowel disease (IBD) 0.0482765687386642 -3.03080895531435 56 3 0.0285714285714286 105 7176 294270,309622,294269 RT1-Db1,RT1-Bb,RT1-Da rno05224 Breast cancer 0.0487267989831252 -3.0215261131182 136 5 0.0476190476190476 105 7176 84426,100360552,303586,84488,25443 Wnt4,Fzd7,Wnt9b,Fgf13,Fgf10 ko05224 Breast cancer 0.0487267989831252 -3.0215261131182 136 5 0.0476190476190476 105 7176 25443,84426,84488,303586,100360552 Fgf10,Wnt4,Fgf13,Wnt9b,Fzd7 ko04261 Adrenergic signaling in cardiomyocytes 0.050006893154478 -2.99559441996667 137 5 0.0476190476190476 105 7176 29413,140729,689560,140727,691455 Adra1d,Cacng8,Ryr2,Cacng6,Calml4 rno04261 Adrenergic signaling in cardiomyocytes 0.050006893154478 -2.99559441996667 137 5 0.0476190476190476 105 7176 140729,29413,691455,140727,689560 Cacng8,Adra1d,Calml4,Cacng6,Ryr2 ko00512 Mucin type O-glycan biosynthesis 0.0511403703143295 -2.9731810679578 25 2 0.019047619047619 105 7176 366061,288611 Galnt3,Galnt17 rno00512 Mucin type O-glycan biosynthesis 0.0511403703143295 -2.9731810679578 25 2 0.019047619047619 105 7176 366061,288611 Galnt3,Galnt17 rno05202 Transcriptional misregulation in cancer 0.0624181266303898 -2.77389955491943 146 5 0.0476190476190476 105 7176 24253,362176,79242,59109,58853 Cebpb,Lmo2,Hpgd,Ntrk1,Nr4a3 ko05202 Transcriptional misregulation in cancer 0.0624181266303898 -2.77389955491943 146 5 0.0476190476190476 105 7176 362176,79242,59109,58853,24253 Lmo2,Hpgd,Ntrk1,Nr4a3,Cebpb rno04750 Inflammatory mediator regulation of TRP channels 0.0656136181198762 -2.7239720112858 104 4 0.0380952380952381 105 7176 59109,691455,24681,310738 Ntrk1,Calml4,Prkcg,Ngf ko04750 Inflammatory mediator regulation of TRP channels 0.0656136181198762 -2.7239720112858 104 4 0.0380952380952381 105 7176 24681,310738,59109,691455 Prkcg,Ngf,Ntrk1,Calml4 ko04151 PI3K-Akt signaling pathway 0.0666414999355569 -2.70842777334028 295 8 0.0761904761904762 105 7176 25443,84488,310738,311144,81008,315744,445442,25724 Fgf10,Fgf13,Ngf,Itga4,Itga7,Itga11,Thbs1,Itgb4 rno04151 PI3K-Akt signaling pathway 0.0666414999355569 -2.70842777334028 295 8 0.0761904761904762 105 7176 25443,84488,310738,311144,315744,81008,445442,25724 Fgf10,Fgf13,Ngf,Itga4,Itga11,Itga7,Thbs1,Itgb4 rno04725 Cholinergic synapse 0.0693677697281395 -2.66833293248176 106 4 0.0380952380952381 105 7176 53949,25302,25743,24681 Chrm5,Chrna7,Kcnj6,Prkcg rno05200 Pathways in cancer 0.0758822110538541 -2.57857299551731 356 9 0.0857142857142857 105 7176 24681,84426,84488,29527,59109,25443,100360552,303586,310999 Prkcg,Wnt4,Fgf13,Ptgs2,Ntrk1,Fgf10,Fzd7,Wnt9b,Plekhg5 rno04670 Leukocyte transendothelial migration 0.079227861410551 -2.53542725653701 111 4 0.0380952380952381 105 7176 295378,311144,24681,50646 Vav3,Itga4,Prkcg,Ptk2b ko04670 Leukocyte transendothelial migration 0.079227861410551 -2.53542725653701 111 4 0.0380952380952381 105 7176 311144,295378,50646,24681 Itga4,Vav3,Ptk2b,Prkcg ko04971 Gastric acid secretion 0.0825403647219195 -2.49446783593813 70 3 0.0285714285714286 105 7176 24785,691455,24681 Slc9a4,Calml4,Prkcg rno04971 Gastric acid secretion 0.0825403647219195 -2.49446783593813 70 3 0.0285714285714286 105 7176 24681,24785,691455 Prkcg,Slc9a4,Calml4 ko04514 Cell adhesion molecules (CAMs) 0.0831593545656346 -2.48699657737845 159 5 0.0476190476190476 105 7176 294270,309622,294269,365527,311144 RT1-Db1,RT1-Bb,RT1-Da,RT1-M6-2,Itga4 rno04514 Cell adhesion molecules (CAMs) 0.0831593545656346 -2.48699657737845 159 5 0.0476190476190476 105 7176 309622,294270,311144,365527,294269 RT1-Bb,RT1-Db1,Itga4,RT1-M6-2,RT1-Da ko04270 Vascular smooth muscle contraction 0.0833585594659591 -2.48460398200501 113 4 0.0380952380952381 105 7176 24681,29413,54286,691455 Prkcg,Adra1d,Prkg1,Calml4 rno04270 Vascular smooth muscle contraction 0.0833585594659591 -2.48460398200501 113 4 0.0380952380952381 105 7176 29413,24681,691455,54286 Adra1d,Prkcg,Calml4,Prkg1 rno_M00141 C1-unit interconversion, eukaryotes 0.0846715610843154 -2.46897549422007 6 1 0.00952380952380952 105 7176 287379 Shmt1 M00029 Urea cycle 0.0846715610843154 -2.46897549422007 6 1 0.00952380952380952 105 7176 29221 Arg1 rno_M00029 Urea cycle 0.0846715610843154 -2.46897549422007 6 1 0.00952380952380952 105 7176 29221 Arg1 M00141 C1-unit interconversion, eukaryotes 0.0846715610843154 -2.46897549422007 6 1 0.00952380952380952 105 7176 287379 Shmt1 rno04260 Cardiac muscle contraction 0.0853044377104091 -2.46152880109672 71 3 0.0285714285714286 105 7176 140727,689560,140729 Cacng6,Ryr2,Cacng8 ko04260 Cardiac muscle contraction 0.0853044377104091 -2.46152880109672 71 3 0.0285714285714286 105 7176 140729,140727,689560 Cacng8,Cacng6,Ryr2 rno04960 Aldosterone-regulated sodium reabsorption 0.106195969690779 -2.24246912107542 38 2 0.019047619047619 105 7176 25672,24681 Nr3c2,Prkcg ko04960 Aldosterone-regulated sodium reabsorption 0.106195969690779 -2.24246912107542 38 2 0.019047619047619 105 7176 24681,25672 Prkcg,Nr3c2 ko05323 Rheumatoid arthritis 0.115006105337293 -2.1627700621386 81 3 0.0285714285714286 105 7176 309622,294270,294269 RT1-Bb,RT1-Db1,RT1-Da rno05323 Rheumatoid arthritis 0.115006105337293 -2.1627700621386 81 3 0.0285714285714286 105 7176 294269,294270,309622 RT1-Da,RT1-Db1,RT1-Bb rno04666 Fc gamma R-mediated phagocytosis 0.118168738726937 -2.13564168676605 82 3 0.0285714285714286 105 7176 360854,295378,24681 Arpc5,Vav3,Prkcg ko04666 Fc gamma R-mediated phagocytosis 0.118168738726937 -2.13564168676605 82 3 0.0285714285714286 105 7176 24681,295378,360854 Prkcg,Vav3,Arpc5 rno05146 Amoebiasis 0.121363827671815 -2.10896240462533 83 3 0.0285714285714286 105 7176 24681,309242,29221 Prkcg,Gna14,Arg1 ko05146 Amoebiasis 0.121363827671815 -2.10896240462533 83 3 0.0285714285714286 105 7176 24681,309242,29221 Prkcg,Gna14,Arg1 rno04550 Signaling pathways regulating pluripotency of stem cells 0.122527419615121 -2.09942044045153 130 4 0.0380952380952381 105 7176 84426,100360552,303586,293847 Wnt4,Fzd7,Wnt9b,Dusp9 ko04550 Signaling pathways regulating pluripotency of stem cells 0.122527419615121 -2.09942044045153 130 4 0.0380952380952381 105 7176 293847,303586,100360552,84426 Dusp9,Wnt9b,Fzd7,Wnt4 ko05204 Chemical carcinogenesis 0.124590726643272 -2.08272110041233 84 3 0.0285714285714286 105 7176 25426,29527,25302 Cyp1b1,Ptgs2,Chrna7 ko04540 Gap junction 0.124590726643272 -2.08272110041233 84 3 0.0285714285714286 105 7176 24681,500377,54286 Prkcg,Tuba8,Prkg1 rno05204 Chemical carcinogenesis 0.124590726643272 -2.08272110041233 84 3 0.0285714285714286 105 7176 25302,29527,25426 Chrna7,Ptgs2,Cyp1b1 rno04540 Gap junction 0.124590726643272 -2.08272110041233 84 3 0.0285714285714286 105 7176 500377,54286,24681 Tuba8,Prkg1,Prkcg ko04727 GABAergic synapse 0.127848787939617 -2.05690705762139 85 3 0.0285714285714286 105 7176 25743,29707,24681 Kcnj6,Gabra5,Prkcg rno04727 GABAergic synapse 0.127848787939617 -2.05690705762139 85 3 0.0285714285714286 105 7176 24681,29707,25743 Prkcg,Gabra5,Kcnj6 ko04658 Th1 and Th2 cell differentiation 0.13113736209595 -2.03150993952398 86 3 0.0285714285714286 105 7176 294270,309622,294269 RT1-Db1,RT1-Bb,RT1-Da rno04658 Th1 and Th2 cell differentiation 0.13113736209595 -2.03150993952398 86 3 0.0285714285714286 105 7176 294269,294270,309622 RT1-Da,RT1-Db1,RT1-Bb ko04310 Wnt signaling pathway 0.135328860106557 -2.00004746199461 135 4 0.0380952380952381 105 7176 24681,303586,84426,100360552 Prkcg,Wnt9b,Wnt4,Fzd7 rno04310 Wnt signaling pathway 0.135328860106557 -2.00004746199461 135 4 0.0380952380952381 105 7176 100360552,84426,303586,24681 Fzd7,Wnt4,Wnt9b,Prkcg ko00430 Taurine and hypotaurine metabolism 0.137133526297892 -1.98680018330142 10 1 0.00952380952380952 105 7176 81718 Cdo1 M00694 cGMP signaling 0.137133526297892 -1.98680018330142 10 1 0.00952380952380952 105 7176 54286 Prkg1 rno00430 Taurine and hypotaurine metabolism 0.137133526297892 -1.98680018330142 10 1 0.00952380952380952 105 7176 81718 Cdo1 rno_M00694 cGMP signaling 0.137133526297892 -1.98680018330142 10 1 0.00952380952380952 105 7176 54286 Prkg1 ko04070 Phosphatidylinositol signaling system 0.13780344449799 -1.98192692435802 88 3 0.0285714285714286 105 7176 24681,25666,691455 Prkcg,Dgkg,Calml4 rno04070 Phosphatidylinositol signaling system 0.13780344449799 -1.98192692435802 88 3 0.0285714285714286 105 7176 24681,25666,691455 Prkcg,Dgkg,Calml4 rno05032 Morphine addiction 0.13780344449799 -1.98192692435802 88 3 0.0285714285714286 105 7176 25743,24681,29707 Kcnj6,Prkcg,Gabra5 ko05032 Morphine addiction 0.13780344449799 -1.98192692435802 88 3 0.0285714285714286 105 7176 24681,29707,25743 Prkcg,Gabra5,Kcnj6 rno05168 Herpes simplex infection 0.138534090462103 -1.97663884312175 187 5 0.0476190476190476 105 7176 294269,365527,25599,294270,309622 RT1-Da,RT1-M6-2,Cd74,RT1-Db1,RT1-Bb ko05168 Herpes simplex infection 0.138534090462103 -1.97663884312175 187 5 0.0476190476190476 105 7176 294270,309622,294269,365527,25599 RT1-Db1,RT1-Bb,RT1-Da,RT1-M6-2,Cd74 rno05030 Cocaine addiction 0.150361357752036 -1.89471383031871 47 2 0.019047619047619 105 7176 24409,24225 Grin2a,Bdnf ko05030 Cocaine addiction 0.150361357752036 -1.89471383031871 47 2 0.019047619047619 105 7176 24409,24225 Grin2a,Bdnf ko04390 Hippo signaling pathway 0.154123679575287 -1.86999988476685 142 4 0.0380952380952381 105 7176 303586,100360552,84426,305922 Wnt9b,Fzd7,Wnt4,Lats2 rno04390 Hippo signaling pathway 0.154123679575287 -1.86999988476685 142 4 0.0380952380952381 105 7176 100360552,84426,303586,305922 Fzd7,Wnt4,Wnt9b,Lats2 ko04913 Ovarian steroidogenesis 0.155475760895181 -1.86126543800074 48 2 0.019047619047619 105 7176 25426,29527 Cyp1b1,Ptgs2 rno04913 Ovarian steroidogenesis 0.155475760895181 -1.86126543800074 48 2 0.019047619047619 105 7176 29527,25426 Ptgs2,Cyp1b1 rno05205 Proteoglycans in cancer 0.156784441438596 -1.85288340150817 195 5 0.0476190476190476 105 7176 445442,84426,100360552,303586,24681 Thbs1,Wnt4,Fzd7,Wnt9b,Prkcg ko05205 Proteoglycans in cancer 0.156784441438596 -1.85288340150817 195 5 0.0476190476190476 105 7176 24681,303586,84426,100360552,445442 Prkcg,Wnt9b,Wnt4,Fzd7,Thbs1 rno04150 mTOR signaling pathway 0.159668732975753 -1.83465402893005 144 4 0.0380952380952381 105 7176 24681,303586,100360552,84426 Prkcg,Wnt9b,Fzd7,Wnt4 ko04150 mTOR signaling pathway 0.159668732975753 -1.83465402893005 144 4 0.0380952380952381 105 7176 100360552,303586,84426,24681 Fzd7,Wnt9b,Wnt4,Prkcg M00683 Hippo signaling 0.174515137519575 -1.74574379313886 13 1 0.00952380952380952 105 7176 305922 Lats2 rno_M00683 Hippo signaling 0.174515137519575 -1.74574379313886 13 1 0.00952380952380952 105 7176 305922 Lats2 rno05014 Amyotrophic lateral sclerosis (ALS) 0.17624662156678 -1.73587100588891 52 2 0.019047619047619 105 7176 50592,24409 Gria1,Grin2a ko05014 Amyotrophic lateral sclerosis (ALS) 0.17624662156678 -1.73587100588891 52 2 0.019047619047619 105 7176 24409,50592 Grin2a,Gria1 rno04659 Th17 cell differentiation 0.176368951240823 -1.73517716427564 99 3 0.0285714285714286 105 7176 294269,294270,309622 RT1-Da,RT1-Db1,RT1-Bb ko04659 Th17 cell differentiation 0.176368951240823 -1.73517716427564 99 3 0.0285714285714286 105 7176 309622,294270,294269 RT1-Bb,RT1-Db1,RT1-Da rno04923 Regulation of lipolysis in adipocytes 0.181507820151841 -1.70645653996938 53 2 0.019047619047619 105 7176 29527,54286 Ptgs2,Prkg1 ko04370 VEGF signaling pathway 0.186792654614639 -1.67775607615197 54 2 0.019047619047619 105 7176 24681,29527 Prkcg,Ptgs2 rno04370 VEGF signaling pathway 0.186792654614639 -1.67775607615197 54 2 0.019047619047619 105 7176 24681,29527 Prkcg,Ptgs2 rno05145 Toxoplasmosis 0.191080706338167 -1.65505939390992 103 3 0.0285714285714286 105 7176 294269,294270,309622 RT1-Da,RT1-Db1,RT1-Bb ko05145 Toxoplasmosis 0.191080706338167 -1.65505939390992 103 3 0.0285714285714286 105 7176 294269,309622,294270 RT1-Da,RT1-Bb,RT1-Db1 rno05214 Glioma 0.218900720567951 -1.51913698269103 60 2 0.019047619047619 105 7176 691455,24681 Calml4,Prkcg ko05214 Glioma 0.218900720567951 -1.51913698269103 60 2 0.019047619047619 105 7176 24681,691455 Prkcg,Calml4 rno00670 One carbon pool by folate 0.221872952578163 -1.50565034661177 17 1 0.00952380952380952 105 7176 287379 Shmt1 ko00670 One carbon pool by folate 0.221872952578163 -1.50565034661177 17 1 0.00952380952380952 105 7176 287379 Shmt1 ko04721 Synaptic vesicle cycle 0.229716401648052 -1.4709097671865 62 2 0.019047619047619 105 7176 116638,266767 Slc17a7,Slc17a8 rno04721 Synaptic vesicle cycle 0.229716401648052 -1.4709097671865 62 2 0.019047619047619 105 7176 116638,266767 Slc17a7,Slc17a8 ko00220 Arginine biosynthesis 0.244532485467018 -1.40840711399719 19 1 0.00952380952380952 105 7176 29221 Arg1 rno00220 Arginine biosynthesis 0.244532485467018 -1.40840711399719 19 1 0.00952380952380952 105 7176 29221 Arg1 ko04115 p53 signaling pathway 0.246004606131505 -1.40240501911326 65 2 0.019047619047619 105 7176 445442,292949 Thbs1,Perp rno04115 p53 signaling pathway 0.246004606131505 -1.40240501911326 65 2 0.019047619047619 105 7176 445442,292949 Thbs1,Perp ko05218 Melanoma 0.256890537630897 -1.35910520843333 67 2 0.019047619047619 105 7176 84488,25443 Fgf13,Fgf10 rno05218 Melanoma 0.256890537630897 -1.35910520843333 67 2 0.019047619047619 105 7176 25443,84488 Fgf10,Fgf13 ko05133 Pertussis 0.262337753801519 -1.33812246879723 68 2 0.019047619047619 105 7176 691455,364867 Calml4,Ticam2 rno05133 Pertussis 0.262337753801519 -1.33812246879723 68 2 0.019047619047619 105 7176 364867,691455 Ticam2,Calml4 rno00340 Histidine metabolism 0.266538261709075 -1.32223747454059 21 1 0.00952380952380952 105 7176 24443 Hdc ko00340 Histidine metabolism 0.266538261709075 -1.32223747454059 21 1 0.00952380952380952 105 7176 24443 Hdc rno04918 Thyroid hormone synthesis 0.267786159532878 -1.3175665291634 69 2 0.019047619047619 105 7176 24856,24681 Ttr,Prkcg ko04918 Thyroid hormone synthesis 0.267786159532878 -1.3175665291634 69 2 0.019047619047619 105 7176 24681,24856 Prkcg,Ttr rno05034 Alcoholism 0.272378871385885 -1.30056127237776 124 3 0.0285714285714286 105 7176 24409,691455,24225 Grin2a,Calml4,Bdnf ko05034 Alcoholism 0.272378871385885 -1.30056127237776 124 3 0.0285714285714286 105 7176 24225,691455,24409 Bdnf,Calml4,Grin2a rno05161 Hepatitis B 0.284354826214539 -1.25753243257738 127 3 0.0285714285714286 105 7176 50646,24681,364867 Ptk2b,Prkcg,Ticam2 rno04210 Apoptosis 0.292365606624633 -1.22975018242757 129 3 0.0285714285714286 105 7176 500377,59109,310738 Tuba8,Ntrk1,Ngf ko04210 Apoptosis 0.292365606624633 -1.22975018242757 129 3 0.0285714285714286 105 7176 310738,59109,500377 Ngf,Ntrk1,Tuba8 rno05206 MicroRNAs in cancer 0.294330523045759 -1.22305191506777 247 5 0.0476190476190476 105 7176 29527,25426,445442,24681,311071 Ptgs2,Cyp1b1,Thbs1,Prkcg,Zeb2 ko05206 MicroRNAs in cancer 0.294330523045759 -1.22305191506777 247 5 0.0476190476190476 105 7176 445442,24681,311071,25426,29527 Thbs1,Prkcg,Zeb2,Cyp1b1,Ptgs2 ko04744 Phototransduction 0.298361861923914 -1.20944822738672 24 1 0.00952380952380952 105 7176 691455 Calml4 rno04744 Phototransduction 0.298361861923914 -1.20944822738672 24 1 0.00952380952380952 105 7176 691455 Calml4 ko01230 Biosynthesis of amino acids 0.305862566356071 -1.18461940747397 76 2 0.019047619047619 105 7176 29221,287379 Arg1,Shmt1 rno01230 Biosynthesis of amino acids 0.305862566356071 -1.18461940747397 76 2 0.019047619047619 105 7176 287379,29221 Shmt1,Arg1 rno01040 Biosynthesis of unsaturated fatty acids 0.308662757404012 -1.17550599808207 25 1 0.00952380952380952 105 7176 246074 Scd rno_M00014 Glucuronate pathway (uronate pathway) 0.308662757404012 -1.17550599808207 25 1 0.00952380952380952 105 7176 290277 Cryl1 M00014 Glucuronate pathway (uronate pathway) 0.308662757404012 -1.17550599808207 25 1 0.00952380952380952 105 7176 290277 Cryl1 ko01040 Biosynthesis of unsaturated fatty acids 0.308662757404012 -1.17550599808207 25 1 0.00952380952380952 105 7176 246074 Scd ko00630 Glyoxylate and dicarboxylate metabolism 0.318813842637503 -1.14314791193753 26 1 0.00952380952380952 105 7176 287379 Shmt1 ko05216 Thyroid cancer 0.318813842637503 -1.14314791193753 26 1 0.00952380952380952 105 7176 59109 Ntrk1 rno04950 Maturity onset diabetes of the young 0.318813842637503 -1.14314791193753 26 1 0.00952380952380952 105 7176 29458 Neurod1 rno05216 Thyroid cancer 0.318813842637503 -1.14314791193753 26 1 0.00952380952380952 105 7176 59109 Ntrk1 rno00630 Glyoxylate and dicarboxylate metabolism 0.318813842637503 -1.14314791193753 26 1 0.00952380952380952 105 7176 287379 Shmt1 ko04950 Maturity onset diabetes of the young 0.318813842637503 -1.14314791193753 26 1 0.00952380952380952 105 7176 29458 Neurod1 rno04064 NF-kappa B signaling pathway 0.32209016262845 -1.13292376446981 79 2 0.019047619047619 105 7176 364867,29527 Ticam2,Ptgs2 ko04064 NF-kappa B signaling pathway 0.32209016262845 -1.13292376446981 79 2 0.019047619047619 105 7176 364867,29527 Ticam2,Ptgs2 rno04072 Phospholipase D signaling pathway 0.324537951581281 -1.12535279565106 137 3 0.0285714285714286 105 7176 54258,50646,25666 Cxcr1,Ptk2b,Dgkg ko04072 Phospholipase D signaling pathway 0.324537951581281 -1.12535279565106 137 3 0.0285714285714286 105 7176 50646,25666,54258 Ptk2b,Dgkg,Cxcr1 rno04925 Aldosterone synthesis and secretion 0.327480254730614 -1.11632751662329 80 2 0.019047619047619 105 7176 691455,24681 Calml4,Prkcg ko04925 Aldosterone synthesis and secretion 0.327480254730614 -1.11632751662329 80 2 0.019047619047619 105 7176 691455,24681 Calml4,Prkcg rno04911 Insulin secretion 0.332859347122432 -1.1000352592434 81 2 0.019047619047619 105 7176 24681,689560 Prkcg,Ryr2 rno01523 Antifolate resistance 0.338675183963115 -1.08271379033068 28 1 0.00952380952380952 105 7176 287379 Shmt1 ko01523 Antifolate resistance 0.338675183963115 -1.08271379033068 28 1 0.00952380952380952 105 7176 287379 Shmt1 rno04912 GnRH signaling pathway 0.343581248987412 -1.06833166257474 83 2 0.019047619047619 105 7176 691455,50646 Calml4,Ptk2b ko04742 Taste transduction 0.343581248987412 -1.06833166257474 83 2 0.019047619047619 105 7176 29707,24473 Gabra5,Htr1a ko04912 GnRH signaling pathway 0.343581248987412 -1.06833166257474 83 2 0.019047619047619 105 7176 50646,691455 Ptk2b,Calml4 rno04742 Taste transduction 0.343581248987412 -1.06833166257474 83 2 0.019047619047619 105 7176 29707,24473 Gabra5,Htr1a rno04657 IL-17 signaling pathway 0.348922481242982 -1.05290549823358 84 2 0.019047619047619 105 7176 29527,24253 Ptgs2,Cebpb ko04657 IL-17 signaling pathway 0.348922481242982 -1.05290549823358 84 2 0.019047619047619 105 7176 29527,24253 Ptgs2,Cebpb ko04144 Endocytosis 0.352388808315941 -1.04302014389224 267 5 0.0476190476190476 105 7176 259242,360854,54258,365527,59109 Wipf3,Arpc5,Cxcr1,RT1-M6-2,Ntrk1 rno04144 Endocytosis 0.352388808315941 -1.04302014389224 267 5 0.0476190476190476 105 7176 360854,259242,54258,365527,59109 Arpc5,Wipf3,Cxcr1,RT1-M6-2,Ntrk1 rno04614 Renin-angiotensin system 0.357962783855478 -1.02732625369616 30 1 0.00952380952380952 105 7176 25153 Mas1 ko04614 Renin-angiotensin system 0.357962783855478 -1.02732625369616 30 1 0.00952380952380952 105 7176 25153 Mas1 rno00250 Alanine, aspartate and glutamate metabolism 0.367396580059826 -1.00131341473702 31 1 0.00952380952380952 105 7176 685325 Ddo ko00250 Alanine, aspartate and glutamate metabolism 0.367396580059826 -1.00131341473702 31 1 0.00952380952380952 105 7176 685325 Ddo rno04215 Apoptosis - multiple species 0.367396580059826 -1.00131341473702 31 1 0.00952380952380952 105 7176 29884 Bok ko04215 Apoptosis - multiple species 0.367396580059826 -1.00131341473702 31 1 0.00952380952380952 105 7176 29884 Bok rno00040 Pentose and glucuronate interconversions 0.376693061391266 -0.976324583908877 32 1 0.00952380952380952 105 7176 290277 Cryl1 ko00040 Pentose and glucuronate interconversions 0.376693061391266 -0.976324583908877 32 1 0.00952380952380952 105 7176 290277 Cryl1 rno05231 Choline metabolism in cancer 0.380648010036041 -0.965880189048543 90 2 0.019047619047619 105 7176 25666,24681 Dgkg,Prkcg ko05231 Choline metabolism in cancer 0.380648010036041 -0.965880189048543 90 2 0.019047619047619 105 7176 24681,25666 Prkcg,Dgkg ko05164 Influenza A 0.380782512698206 -0.965526899655623 151 3 0.0285714285714286 105 7176 294270,309622,294269 RT1-Db1,RT1-Bb,RT1-Da rno05164 Influenza A 0.380782512698206 -0.965526899655623 151 3 0.0285714285714286 105 7176 294270,309622,294269 RT1-Db1,RT1-Bb,RT1-Da M00355 Spliceosome, 35S U5-snRNP 0.385854207605583 -0.952295681367777 33 1 0.00952380952380952 105 7176 361859 Cdc40 rno_M00355 Spliceosome, 35S U5-snRNP 0.385854207605583 -0.952295681367777 33 1 0.00952380952380952 105 7176 361859 Cdc40 ko04915 Estrogen signaling pathway 0.391084663045612 -0.938831212907487 92 2 0.019047619047619 105 7176 25743,691455 Kcnj6,Calml4 rno04915 Estrogen signaling pathway 0.391084663045612 -0.938831212907487 92 2 0.019047619047619 105 7176 691455,25743 Calml4,Kcnj6 rno05143 African trypanosomiasis 0.394881970200109 -0.929168368353482 34 1 0.00952380952380952 105 7176 24681 Prkcg ko05143 African trypanosomiasis 0.394881970200109 -0.929168368353482 34 1 0.00952380952380952 105 7176 24681 Prkcg rno04972 Pancreatic secretion 0.401444023634176 -0.912687173411625 94 2 0.019047619047619 105 7176 24681,689560 Prkcg,Ryr2 ko04972 Pancreatic secretion 0.401444023634176 -0.912687173411625 94 2 0.019047619047619 105 7176 24681,689560 Prkcg,Ryr2 rno04022 cGMP-PKG signaling pathway 0.404639237934275 -0.904759379380081 157 3 0.0285714285714286 105 7176 691455,54286,29413 Calml4,Prkg1,Adra1d ko04022 cGMP-PKG signaling pathway 0.404639237934275 -0.904759379380081 157 3 0.0285714285714286 105 7176 29413,54286,691455 Adra1d,Prkg1,Calml4 rno04530 Tight junction 0.404639237934275 -0.904759379380081 157 3 0.0285714285714286 105 7176 365603,314640,500377 Bves,Tjp3,Tuba8 ko04530 Tight junction 0.404639237934275 -0.904759379380081 157 3 0.0285714285714286 105 7176 314640,500377,365603 Tjp3,Tuba8,Bves ko05219 Bladder cancer 0.421184055484089 -0.864685354414882 37 1 0.00952380952380952 105 7176 445442 Thbs1 rno05219 Bladder cancer 0.421184055484089 -0.864685354414882 37 1 0.00952380952380952 105 7176 445442 Thbs1 ko00260 Glycine, serine and threonine metabolism 0.42969724699266 -0.844674395034232 38 1 0.00952380952380952 105 7176 287379 Shmt1 rno00260 Glycine, serine and threonine metabolism 0.42969724699266 -0.844674395034232 38 1 0.00952380952380952 105 7176 287379 Shmt1 rno04062 Chemokine signaling pathway 0.436034873561301 -0.830033053599409 165 3 0.0285714285714286 105 7176 50646,54258,295378 Ptk2b,Cxcr1,Vav3 ko04062 Chemokine signaling pathway 0.436034873561301 -0.830033053599409 165 3 0.0285714285714286 105 7176 50646,295378,54258 Ptk2b,Vav3,Cxcr1 rno04668 TNF signaling pathway 0.43703349640041 -0.827745436022216 101 2 0.019047619047619 105 7176 29527,24253 Ptgs2,Cebpb ko04668 TNF signaling pathway 0.43703349640041 -0.827745436022216 101 2 0.019047619047619 105 7176 24253,29527 Cebpb,Ptgs2 ko00565 Ether lipid metabolism 0.438086402087122 -0.825339123020788 39 1 0.00952380952380952 105 7176 301265 Pla2g7 rno00565 Ether lipid metabolism 0.438086402087122 -0.825339123020788 39 1 0.00952380952380952 105 7176 301265 Pla2g7 ko00380 Tryptophan metabolism 0.462527422057324 -0.77104943285254 42 1 0.00952380952380952 105 7176 25426 Cyp1b1 rno00380 Tryptophan metabolism 0.462527422057324 -0.77104943285254 42 1 0.00952380952380952 105 7176 25426 Cyp1b1 rno00270 Cysteine and methionine metabolism 0.470438078161743 -0.754090937200778 43 1 0.00952380952380952 105 7176 81718 Cdo1 ko00270 Cysteine and methionine metabolism 0.470438078161743 -0.754090937200778 43 1 0.00952380952380952 105 7176 81718 Cdo1 ko00600 Sphingolipid metabolism 0.478233395950828 -0.737656389610883 44 1 0.00952380952380952 105 7176 83537 Smpd2 rno00600 Sphingolipid metabolism 0.478233395950828 -0.737656389610883 44 1 0.00952380952380952 105 7176 83537 Smpd2 rno04919 Thyroid hormone signaling pathway 0.481079766724236 -0.731722187439989 110 2 0.019047619047619 105 7176 24681,84426 Prkcg,Wnt4 rno00330 Arginine and proline metabolism 0.500943857717396 -0.691261244620832 47 1 0.00952380952380952 105 7176 29221 Arg1 ko00330 Arginine and proline metabolism 0.500943857717396 -0.691261244620832 47 1 0.00952380952380952 105 7176 29221 Arg1 rno04961 Endocrine and other factor-regulated calcium reabsorption 0.50829424275468 -0.676694781064643 48 1 0.00952380952380952 105 7176 24681 Prkcg ko04961 Endocrine and other factor-regulated calcium reabsorption 0.50829424275468 -0.676694781064643 48 1 0.00952380952380952 105 7176 24681 Prkcg ko04071 Sphingolipid signaling pathway 0.509265081984545 -0.674786608242007 116 2 0.019047619047619 105 7176 24681,83537 Prkcg,Smpd2 rno04071 Sphingolipid signaling pathway 0.509265081984545 -0.674786608242007 116 2 0.019047619047619 105 7176 24681,83537 Prkcg,Smpd2 ko01212 Fatty acid metabolism 0.51553738311424 -0.662545459989083 49 1 0.00952380952380952 105 7176 246074 Scd rno01212 Fatty acid metabolism 0.51553738311424 -0.662545459989083 49 1 0.00952380952380952 105 7176 246074 Scd rno05144 Malaria 0.543468165106929 -0.609784147996685 53 1 0.00952380952380952 105 7176 445442 Thbs1 ko05144 Malaria 0.543468165106929 -0.609784147996685 53 1 0.00952380952380952 105 7176 445442 Thbs1 rno04371 Apelin signaling pathway 0.553996603372363 -0.590596723350467 126 2 0.019047619047619 105 7176 689560,691455 Ryr2,Calml4 ko00561 Glycerolipid metabolism 0.556829346562945 -0.585496465598411 55 1 0.00952380952380952 105 7176 25666 Dgkg rno00561 Glycerolipid metabolism 0.556829346562945 -0.585496465598411 55 1 0.00952380952380952 105 7176 25666 Dgkg rno05223 Non-small cell lung cancer 0.563363951060256 -0.573829410215552 56 1 0.00952380952380952 105 7176 24681 Prkcg ko05223 Non-small cell lung cancer 0.563363951060256 -0.573829410215552 56 1 0.00952380952380952 105 7176 24681 Prkcg rno04060 Cytokine-cytokine receptor interaction 0.578241404996868 -0.547763841799702 204 3 0.0285714285714286 105 7176 500592,84348,54258 Tnfrsf25,Ackr3,Cxcr1 ko04060 Cytokine-cytokine receptor interaction 0.578241404996868 -0.547763841799702 204 3 0.0285714285714286 105 7176 84348,54258,500592 Ackr3,Cxcr1,Tnfrsf25 ko05230 Central carbon metabolism in cancer 0.594632559013917 -0.519811612073506 61 1 0.00952380952380952 105 7176 59109 Ntrk1 rno05230 Central carbon metabolism in cancer 0.594632559013917 -0.519811612073506 61 1 0.00952380952380952 105 7176 59109 Ntrk1 ko00980 Metabolism of xenobiotics by cytochrome P450 0.600614791092461 -0.509801496542576 62 1 0.00952380952380952 105 7176 25426 Cyp1b1 ko04664 Fc epsilon RI signaling pathway 0.600614791092461 -0.509801496542576 62 1 0.00952380952380952 105 7176 295378 Vav3 rno04664 Fc epsilon RI signaling pathway 0.600614791092461 -0.509801496542576 62 1 0.00952380952380952 105 7176 295378 Vav3 rno00980 Metabolism of xenobiotics by cytochrome P450 0.600614791092461 -0.509801496542576 62 1 0.00952380952380952 105 7176 25426 Cyp1b1 ko04520 Adherens junction 0.612318157819523 -0.490503265835003 64 1 0.00952380952380952 105 7176 498281 Nectin4 rno04520 Adherens junction 0.612318157819523 -0.490503265835003 64 1 0.00952380952380952 105 7176 498281 Nectin4 ko04662 B cell receptor signaling pathway 0.623681746621567 -0.472115062157681 66 1 0.00952380952380952 105 7176 295378 Vav3 rno04662 B cell receptor signaling pathway 0.623681746621567 -0.472115062157681 66 1 0.00952380952380952 105 7176 295378 Vav3 ko04924 Renin secretion 0.629239189187274 -0.463243825587442 67 1 0.00952380952380952 105 7176 691455 Calml4 rno04924 Renin secretion 0.629239189187274 -0.463243825587442 67 1 0.00952380952380952 105 7176 691455 Calml4 rno05222 Small cell lung cancer 0.634715330015475 -0.454578679793797 68 1 0.00952380952380952 105 7176 29527 Ptgs2 ko05222 Small cell lung cancer 0.634715330015475 -0.454578679793797 68 1 0.00952380952380952 105 7176 29527 Ptgs2 rno00590 Arachidonic acid metabolism 0.65583018620005 -0.421853386048653 72 1 0.00952380952380952 105 7176 29527 Ptgs2 ko00590 Arachidonic acid metabolism 0.65583018620005 -0.421853386048653 72 1 0.00952380952380952 105 7176 29527 Ptgs2 rno05100 Bacterial invasion of epithelial cells 0.660917155583821 -0.414126778930963 73 1 0.00952380952380952 105 7176 360854 Arpc5 ko05100 Bacterial invasion of epithelial cells 0.660917155583821 -0.414126778930963 73 1 0.00952380952380952 105 7176 360854 Arpc5 ko04974 Protein digestion and absorption 0.670868728887871 -0.399181796189916 75 1 0.00952380952380952 105 7176 94341 Kcnj13 rno04974 Protein digestion and absorption 0.670868728887871 -0.399181796189916 75 1 0.00952380952380952 105 7176 94341 Kcnj13 ko00140 Steroid hormone biosynthesis 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 25426 Cyp1b1 rno04610 Complement and coagulation cascades 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 306761 F12 ko03320 PPAR signaling pathway 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 246074 Scd rno05132 Salmonella infection 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 360854 Arpc5 ko04610 Complement and coagulation cascades 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 306761 F12 rno00830 Retinol metabolism 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 24188 Aldh1a1 ko05132 Salmonella infection 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 360854 Arpc5 rno01521 EGFR tyrosine kinase inhibitor resistance 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 24681 Prkcg rno03320 PPAR signaling pathway 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 246074 Scd ko01521 EGFR tyrosine kinase inhibitor resistance 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 24681 Prkcg rno00140 Steroid hormone biosynthesis 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 25426 Cyp1b1 ko00830 Retinol metabolism 0.680530938968518 -0.384881992871192 77 1 0.00952380952380952 105 7176 24188 Aldh1a1 rno05010 Alzheimer's disease 0.680786957792234 -0.384505859085918 159 2 0.019047619047619 105 7176 24409,691455 Grin2a,Calml4 ko05010 Alzheimer's disease 0.680786957792234 -0.384505859085918 159 2 0.019047619047619 105 7176 691455,24409 Calml4,Grin2a rno04350 TGF-beta signaling pathway 0.694499866236919 -0.364563309391186 80 1 0.00952380952380952 105 7176 445442 Thbs1 ko04350 TGF-beta signaling pathway 0.694499866236919 -0.364563309391186 80 1 0.00952380952380952 105 7176 445442 Thbs1 rno04146 Peroxisome 0.699020372730407 -0.358075391635986 81 1 0.00952380952380952 105 7176 685325 Ddo ko04146 Peroxisome 0.699020372730407 -0.358075391635986 81 1 0.00952380952380952 105 7176 685325 Ddo rno00564 Glycerophospholipid metabolism 0.699020372730407 -0.358075391635986 81 1 0.00952380952380952 105 7176 25666 Dgkg ko00564 Glycerophospholipid metabolism 0.699020372730407 -0.358075391635986 81 1 0.00952380952380952 105 7176 25666 Dgkg rno04012 ErbB signaling pathway 0.7034746166843 -0.351723484550856 82 1 0.00952380952380952 105 7176 24681 Prkcg ko04012 ErbB signaling pathway 0.7034746166843 -0.351723484550856 82 1 0.00952380952380952 105 7176 24681 Prkcg ko04620 Toll-like receptor signaling pathway 0.720648002554702 -0.327604468184193 86 1 0.00952380952380952 105 7176 364867 Ticam2 rno04620 Toll-like receptor signaling pathway 0.720648002554702 -0.327604468184193 86 1 0.00952380952380952 105 7176 364867 Ticam2 ko04922 Glucagon signaling pathway 0.744577581032219 -0.294938226736767 92 1 0.00952380952380952 105 7176 691455 Calml4 rno04922 Glucagon signaling pathway 0.744577581032219 -0.294938226736767 92 1 0.00952380952380952 105 7176 691455 Calml4 rno04066 HIF-1 signaling pathway 0.769939450552269 -0.261443402872756 99 1 0.00952380952380952 105 7176 24681 Prkcg rno05142 Chagas disease (American trypanosomiasis) 0.773352811830407 -0.257019915595362 100 1 0.00952380952380952 105 7176 309242 Gna14 ko05142 Chagas disease (American trypanosomiasis) 0.773352811830407 -0.257019915595362 100 1 0.00952380952380952 105 7176 309242 Gna14 rno04660 T cell receptor signaling pathway 0.773352811830407 -0.257019915595362 100 1 0.00952380952380952 105 7176 295378 Vav3 ko04660 T cell receptor signaling pathway 0.773352811830407 -0.257019915595362 100 1 0.00952380952380952 105 7176 295378 Vav3 rno01100 Metabolic pathways 0.786912295944563 -0.239638477760049 1200 15 0.142857142857143 105 7176 288611,64544,29221,366061,117108,287379,24188,83537,290277,25666,24443,29527,301265,81718,291770 Galnt17,B3gat2,Arg1,Galnt3,B3gat1,Shmt1,Aldh1a1,Smpd2,Cryl1,Dgkg,Hdc,Ptgs2,Pla2g7,Cdo1,Chst9 ko04114 Oocyte meiosis 0.792804646303479 -0.232178435358559 106 1 0.00952380952380952 105 7176 691455 Calml4 rno04114 Oocyte meiosis 0.792804646303479 -0.232178435358559 106 1 0.00952380952380952 105 7176 691455 Calml4 rno01200 Carbon metabolism 0.810601578111177 -0.209978617946526 112 1 0.00952380952380952 105 7176 287379 Shmt1 ko01200 Carbon metabolism 0.810601578111177 -0.209978617946526 112 1 0.00952380952380952 105 7176 287379 Shmt1 rno04611 Platelet activation 0.813416815129046 -0.206511613078177 113 1 0.00952380952380952 105 7176 54286 Prkg1 ko04152 AMPK signaling pathway 0.824269232675876 -0.19325806375581 117 1 0.00952380952380952 105 7176 246074 Scd rno04152 AMPK signaling pathway 0.824269232675876 -0.19325806375581 117 1 0.00952380952380952 105 7176 246074 Scd ko03040 Spliceosome 0.831996035102084 -0.183927603674587 120 1 0.00952380952380952 105 7176 361859 Cdc40 rno03040 Spliceosome 0.831996035102084 -0.183927603674587 120 1 0.00952380952380952 105 7176 361859 Cdc40 rno04068 FoxO signaling pathway 0.839386187751093 -0.175084383124995 123 1 0.00952380952380952 105 7176 29548 Homer3 ko04910 Insulin signaling pathway 0.846454223205937 -0.166699156596023 126 1 0.00952380952380952 105 7176 691455 Calml4 rno04910 Insulin signaling pathway 0.846454223205937 -0.166699156596023 126 1 0.00952380952380952 105 7176 691455 Calml4 ko05418 Fluid shear stress and atherosclerosis 0.873687632828603 -0.135032366718635 139 1 0.00952380952380952 105 7176 691455 Calml4 rno05418 Fluid shear stress and atherosclerosis 0.873687632828603 -0.135032366718635 139 1 0.00952380952380952 105 7176 691455 Calml4 ko05016 Huntington's disease 0.909303285900256 -0.0950765925976591 161 1 0.00952380952380952 105 7176 24225 Bdnf rno05016 Huntington's disease 0.909303285900256 -0.0950765925976591 161 1 0.00952380952380952 105 7176 24225 Bdnf ko05203 Viral carcinogenesis 0.94737280062494 -0.0540625983990802 197 1 0.00952380952380952 105 7176 365527 RT1-M6-2 rno05203 Viral carcinogenesis 0.94737280062494 -0.0540625983990802 197 1 0.00952380952380952 105 7176 365527 RT1-M6-2 rno05169 Epstein-Barr virus infection 0.956132447200092 -0.0448588324306132 209 1 0.00952380952380952 105 7176 365527 RT1-M6-2 ko05169 Epstein-Barr virus infection 0.956132447200092 -0.0448588324306132 209 1 0.00952380952380952 105 7176 365527 RT1-M6-2 rno04740 Olfactory transduction 0.999999415506992 -5.84493179131379e-07 1085 2 0.019047619047619 105 7176 691455,54286 Calml4,Prkg1 ko04740 Olfactory transduction 0.999999415506992 -5.84493179131379e-07 1085 2 0.019047619047619 105 7176 54286,691455 Prkg1,Calml4 rno_M00690 MAPK (ERK5) signaling 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00384 Cul3-SPOP complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00286 GINS complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00262 DNA polymerase delta complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00393 TRAMP complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 ko00290 Valine, leucine and isoleucine biosynthesis 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00148 Succinate dehydrogenase (ubiquinone) 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00402 Translocon-associated protein (TRAP) complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00261 DNA polymerase alpha / primase complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00286 GINS complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00005 PRPP biosynthesis, ribose 5P => PRPP 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 ko00524 Neomycin, kanamycin and gentamicin biosynthesis 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00685 Apoptotic machinery 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00395 Decapping complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00015 Proline biosynthesis, glutamate => proline 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00690 MAPK (ERK5) signaling 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00262 DNA polymerase delta complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno00290 Valine, leucine and isoleucine biosynthesis 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00402 Translocon-associated protein (TRAP) complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00263 DNA polymerase epsilon complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00263 DNA polymerase epsilon complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00015 Proline biosynthesis, glutamate => proline 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno00524 Neomycin, kanamycin and gentamicin biosynthesis 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00381 SCF-SKP2 complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00425 H/ACA ribonucleoprotein complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00685 Apoptotic machinery 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00027 GABA (gamma-Aminobutyrate) shunt 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00148 Succinate dehydrogenase (ubiquinone) 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00381 SCF-SKP2 complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00393 TRAMP complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00395 Decapping complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00005 PRPP biosynthesis, ribose 5P => PRPP 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00401 Sec61 complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00401 Sec61 complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno_M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00261 DNA polymerase alpha / primase complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00027 GABA (gamma-Aminobutyrate) shunt 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00384 Cul3-SPOP complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00425 H/ACA ribonucleoprotein complex 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 0.999999999997496 -2.50418514280474e-12 4 0 0 105 7176 rno04136 Autophagy - other 0.999999999997683 -2.31663521138953e-12 31 0 0 105 7176 ko04136 Autophagy - other 0.999999999997683 -2.31663521138953e-12 31 0 0 105 7176 rno00020 Citrate cycle (TCA cycle) 0.999999999997683 -2.31663521138953e-12 31 0 0 105 7176 ko00020 Citrate cycle (TCA cycle) 0.999999999997683 -2.31663521138953e-12 31 0 0 105 7176 rno_M00004 Pentose phosphate pathway (Pentose phosphate cycle) 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00076 Dermatan sulfate degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00296 BER complex 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00404 COPII complex 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00404 COPII complex 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00035 Methionine degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00678 Hedgehog signaling 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00678 Hedgehog signaling 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00004 Pentose phosphate pathway (Pentose phosphate cycle) 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno00072 Synthesis and degradation of ketone bodies 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 ko00072 Synthesis and degradation of ketone bodies 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00681 Activin signaling 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00098 Acylglycerol degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00076 Dermatan sulfate degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00098 Acylglycerol degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00412 ESCRT-III complex 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00035 Methionine degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00296 BER complex 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00077 Chondroitin sulfate degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00077 Chondroitin sulfate degradation 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00681 Activin signaling 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00412 ESCRT-III complex 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 0.999999999998603 -1.39678706755764e-12 10 0 0 105 7176 rno_M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00180 RNA polymerase II, eukaryotes 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00182 RNA polymerase I, eukaryotes 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00388 ECS complex 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno00130 Ubiquinone and other terpenoid-quinone biosynthesis 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00094 Ceramide biosynthesis 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00182 RNA polymerase I, eukaryotes 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00180 RNA polymerase II, eukaryotes 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 ko00920 Sulfur metabolism 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno00920 Sulfur metabolism 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00034 Methionine salvage pathway 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00094 Ceramide biosynthesis 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00034 Methionine salvage pathway 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00388 ECS complex 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 0.999999999999623 -3.76740020101505e-13 11 0 0 105 7176 rno_M00397 Lsm 1-7 complex 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00065 GPI-anchor biosynthesis, core oligosaccharide 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00072 N-glycosylation by oligosaccharyltransferase 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00396 Lsm 2-8 complex 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00687 MAPK (ERK1/2) signaling 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00072 N-glycosylation by oligosaccharyltransferase 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00396 Lsm 2-8 complex 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00687 MAPK (ERK1/2) signaling 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00120 Coenzyme A biosynthesis, pantothenate => CoA 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno_M00065 GPI-anchor biosynthesis, core oligosaccharide 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00397 Lsm 1-7 complex 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00120 Coenzyme A biosynthesis, pantothenate => CoA 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 1.00000000000081 8.05184414144905e-13 7 0 0 105 7176 rno00982 Drug metabolism - cytochrome P450 1.000000000001 9.9846817554571e-13 62 0 0 105 7176 ko00010 Glycolysis / Gluconeogenesis 1.000000000001 9.9846817554571e-13 62 0 0 105 7176 ko00982 Drug metabolism - cytochrome P450 1.000000000001 9.9846817554571e-13 62 0 0 105 7176 rno00010 Glycolysis / Gluconeogenesis 1.000000000001 9.9846817554571e-13 62 0 0 105 7176 M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00291 MRN complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00100 Sphingosine degradation 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00020 Serine biosynthesis, glycerate-3P => serine 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 ko00785 Lipoic acid metabolism 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno00471 D-Glutamine and D-glutamate metabolism 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00020 Serine biosynthesis, glycerate-3P => serine 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00390 Exosome, archaea 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00387 SCF-FBW7 complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00118 Glutathione biosynthesis, glutamate => glutathione 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00408 ESCRT-0 complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00410 ESCRT-II complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno00785 Lipoic acid metabolism 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00291 MRN complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00387 SCF-FBW7 complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00118 Glutathione biosynthesis, glutamate => glutathione 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00082 Fatty acid biosynthesis, initiation 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00400 p97-Ufd1-Npl4 complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 ko00471 D-Glutamine and D-glutamate metabolism 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00410 ESCRT-II complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00100 Sphingosine degradation 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00288 RPA complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00408 ESCRT-0 complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00400 p97-Ufd1-Npl4 complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00390 Exosome, archaea 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00082 Fatty acid biosynthesis, initiation 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 M00288 RPA complex 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 rno_M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 1.00000000000137 1.37314983610919e-12 3 0 0 105 7176 ko00860 Porphyrin and chlorophyll metabolism 1.00000000000295 2.95032738607837e-12 38 0 0 105 7176 ko04216 Ferroptosis 1.00000000000295 2.95032738607837e-12 38 0 0 105 7176 rno00860 Porphyrin and chlorophyll metabolism 1.00000000000295 2.95032738607837e-12 38 0 0 105 7176 ko00620 Pyruvate metabolism 1.00000000000295 2.95032738607837e-12 38 0 0 105 7176 rno00620 Pyruvate metabolism 1.00000000000295 2.95032738607837e-12 38 0 0 105 7176 rno04216 Ferroptosis 1.00000000000295 2.95032738607837e-12 38 0 0 105 7176 ko04130 SNARE interactions in vesicular transport 1.00000000000356 3.5610623810494e-12 32 0 0 105 7176 rno04130 SNARE interactions in vesicular transport 1.00000000000356 3.5610623810494e-12 32 0 0 105 7176 ko05020 Prion diseases 1.00000000000356 3.5610623810494e-12 32 0 0 105 7176 rno05020 Prion diseases 1.00000000000356 3.5610623810494e-12 32 0 0 105 7176 rno05340 Primary immunodeficiency 1.00000000000356 3.5610623810494e-12 32 0 0 105 7176 ko05340 Primary immunodeficiency 1.00000000000356 3.5610623810494e-12 32 0 0 105 7176 ko00640 Propanoate metabolism 1.00000000000361 3.60628091729099e-12 30 0 0 105 7176 rno00640 Propanoate metabolism 1.00000000000361 3.60628091729099e-12 30 0 0 105 7176 ko03015 mRNA surveillance pathway 1.00000000000371 3.71289655978818e-12 80 0 0 105 7176 rno03015 mRNA surveillance pathway 1.00000000000371 3.71289655978818e-12 80 0 0 105 7176 rno05221 Acute myeloid leukemia 1.00000000000391 3.90757179387845e-12 52 0 0 105 7176 ko00983 Drug metabolism - other enzymes 1.00000000000391 3.90757179387845e-12 52 0 0 105 7176 ko05221 Acute myeloid leukemia 1.00000000000391 3.90757179387845e-12 52 0 0 105 7176 rno00983 Drug metabolism - other enzymes 1.00000000000391 3.90757179387845e-12 52 0 0 105 7176 rno_M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 ko01210 2-Oxocarboxylic acid metabolism 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno_M00337 Immunoproteasome 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 M00684 JAK-STAT signaling 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno01210 2-Oxocarboxylic acid metabolism 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno_M00679 BMP signaling 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 M00337 Immunoproteasome 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 M00679 BMP signaling 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 ko00511 Other glycan degradation 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno00511 Other glycan degradation 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno_M00684 JAK-STAT signaling 1.00000000000397 3.97385991776807e-12 18 0 0 105 7176 rno00280 Valine, leucine and isoleucine degradation 1.00000000000439 4.38725869664427e-12 49 0 0 105 7176 ko00280 Valine, leucine and isoleucine degradation 1.00000000000439 4.38725869664427e-12 49 0 0 105 7176 ko04920 Adipocytokine signaling pathway 1.00000000000454 4.54473544701859e-12 70 0 0 105 7176 rno04920 Adipocytokine signaling pathway 1.00000000000454 4.54473544701859e-12 70 0 0 105 7176 rno_M00688 MAPK (JNK) signaling 1.00000000000481 4.80859378840798e-12 20 0 0 105 7176 M00688 MAPK (JNK) signaling 1.00000000000481 4.80859378840798e-12 20 0 0 105 7176 ko00592 alpha-Linolenic acid metabolism 1.00000000000481 4.80859378840798e-12 20 0 0 105 7176 rno00592 alpha-Linolenic acid metabolism 1.00000000000481 4.80859378840798e-12 20 0 0 105 7176 ko00750 Vitamin B6 metabolism 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00351 Spliceosome, U1-snRNP 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00290 Holo-TFIIH complex 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00290 Holo-TFIIH complex 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00152 Cytochrome bc1 complex 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00351 Spliceosome, U1-snRNP 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00426 Survival motor neuron (SMN) complex 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00361 Nucleotide sugar biosynthesis, eukaryotes 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno00750 Vitamin B6 metabolism 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00361 Nucleotide sugar biosynthesis, eukaryotes 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00152 Cytochrome bc1 complex 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00426 Survival motor neuron (SMN) complex 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 1.00000000000492 4.91643038622258e-12 9 0 0 105 7176 rno_M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 ko00472 D-Arginine and D-ornithine metabolism 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 rno_M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 rno00472 D-Arginine and D-ornithine metabolism 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 M00414 Bloom's syndrome complex 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 rno_M00414 Bloom's syndrome complex 1.00000000000525 5.25208175561342e-12 1 0 0 105 7176 ko03420 Nucleotide excision repair 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 ko04975 Fat digestion and absorption 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 rno03022 Basal transcription factors 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 ko03022 Basal transcription factors 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 rno04340 Hedgehog signaling pathway 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 rno04975 Fat digestion and absorption 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 rno03420 Nucleotide excision repair 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 ko04340 Hedgehog signaling pathway 1.00000000000553 5.53422483569235e-12 39 0 0 105 7176 rno00100 Steroid biosynthesis 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 rno00514 Other types of O-glycan biosynthesis 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 M00154 Cytochrome c oxidase 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 ko00100 Steroid biosynthesis 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 rno_M00003 Gluconeogenesis, oxaloacetate => fructose-6P 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 ko00514 Other types of O-glycan biosynthesis 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 M00341 Proteasome, 19S regulatory particle (PA700) 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 rno_M00341 Proteasome, 19S regulatory particle (PA700) 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 rno_M00352 Spliceosome, U2-snRNP 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 M00352 Spliceosome, U2-snRNP 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 M00003 Gluconeogenesis, oxaloacetate => fructose-6P 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 rno_M00154 Cytochrome c oxidase 1.00000000000566 5.65768211943253e-12 19 0 0 105 7176 rno05012 Parkinson's disease 1.00000000000566 5.66412217722437e-12 122 0 0 105 7176 rno04977 Vitamin digestion and absorption 1.00000000000583 5.83056431741477e-12 24 0 0 105 7176 ko04977 Vitamin digestion and absorption 1.00000000000583 5.83056431741477e-12 24 0 0 105 7176 M00160 V-type ATPase, eukaryotes 1.00000000000583 5.83056431741477e-12 24 0 0 105 7176 rno_M00160 V-type ATPase, eukaryotes 1.00000000000583 5.83056431741477e-12 24 0 0 105 7176 rno04930 Type II diabetes mellitus 1.00000000000601 6.00724841170361e-12 45 0 0 105 7176 ko04930 Type II diabetes mellitus 1.00000000000601 6.00724841170361e-12 45 0 0 105 7176 ko04330 Notch signaling pathway 1.00000000000633 6.32759373301465e-12 43 0 0 105 7176 rno04330 Notch signaling pathway 1.00000000000633 6.32759373301465e-12 43 0 0 105 7176 rno00760 Nicotinate and nicotinamide metabolism 1.00000000000672 6.71642677301006e-12 29 0 0 105 7176 ko00760 Nicotinate and nicotinamide metabolism 1.00000000000672 6.71642677301006e-12 29 0 0 105 7176 ko05134 Legionellosis 1.00000000000698 6.98398181489634e-12 51 0 0 105 7176 rno05134 Legionellosis 1.00000000000698 6.98398181489634e-12 51 0 0 105 7176 ko00480 Glutathione metabolism 1.00000000000706 7.06476226219868e-12 54 0 0 105 7176 rno00480 Glutathione metabolism 1.00000000000706 7.06476226219868e-12 54 0 0 105 7176 rno_M00391 Exosome, eukaryotes 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno_M00406 TREX complex 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 M00409 ESCRT-I complex 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 M00086 beta-Oxidation, acyl-CoA synthesis 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 ko00740 Riboflavin metabolism 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno_M00086 beta-Oxidation, acyl-CoA synthesis 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 M00406 TREX complex 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno_M00680 TGF-beta signaling 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 M00693 Cell cycle - G2/M transition 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 M00680 TGF-beta signaling 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno_M00409 ESCRT-I complex 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 ko04122 Sulfur relay system 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno04122 Sulfur relay system 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 M00391 Exosome, eukaryotes 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno_M00693 Cell cycle - G2/M transition 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno00740 Riboflavin metabolism 1.00000000000731 7.31180961334099e-12 8 0 0 105 7176 rno03050 Proteasome 1.0000000000078 7.79611290167129e-12 46 0 0 105 7176 rno00520 Amino sugar and nucleotide sugar metabolism 1.0000000000078 7.79611290167129e-12 46 0 0 105 7176 ko00071 Fatty acid degradation 1.0000000000078 7.79611290167129e-12 46 0 0 105 7176 ko00520 Amino sugar and nucleotide sugar metabolism 1.0000000000078 7.79611290167129e-12 46 0 0 105 7176 ko03050 Proteasome 1.0000000000078 7.79611290167129e-12 46 0 0 105 7176 rno00071 Fatty acid degradation 1.0000000000078 7.79611290167129e-12 46 0 0 105 7176 rno03410 Base excision repair 1.00000000000807 8.07183054148161e-12 33 0 0 105 7176 rno03030 DNA replication 1.00000000000807 8.07183054148161e-12 33 0 0 105 7176 ko00350 Tyrosine metabolism 1.00000000000807 8.07183054148161e-12 33 0 0 105 7176 rno00350 Tyrosine metabolism 1.00000000000807 8.07183054148161e-12 33 0 0 105 7176 ko03410 Base excision repair 1.00000000000807 8.07183054148161e-12 33 0 0 105 7176 ko03030 DNA replication 1.00000000000807 8.07183054148161e-12 33 0 0 105 7176 ko02010 ABC transporters 1.0000000000082 8.20262992029507e-12 40 0 0 105 7176 rno02010 ABC transporters 1.0000000000082 8.20262992029507e-12 40 0 0 105 7176 rno_M00692 Cell cycle - G1/S transition 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 M00403 HRD1/SEL1 ERAD complex 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 M00692 Cell cycle - G1/S transition 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 rno03450 Non-homologous end-joining 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 rno_M00403 HRD1/SEL1 ERAD complex 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 ko03450 Non-homologous end-joining 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 rno_M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 rno_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 1.00000000000893 8.92635702614577e-12 12 0 0 105 7176 rno05215 Prostate cancer 1.0000000000094 9.39809181500737e-12 82 0 0 105 7176 ko05215 Prostate cancer 1.0000000000094 9.39809181500737e-12 82 0 0 105 7176 M00083 Fatty acid biosynthesis, elongation 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 ko00780 Biotin metabolism 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00151 Cytochrome bc1 complex respiratory unit 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00392 Ski complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno00780 Biotin metabolism 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno00300 Lysine biosynthesis 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00103 Cholecalciferol biosynthesis 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00151 Cytochrome bc1 complex respiratory unit 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00083 Fatty acid biosynthesis, elongation 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00294 DNA polymerase gamma complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 ko00300 Lysine biosynthesis 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00294 DNA polymerase gamma complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00293 DNA polymerase zeta complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00066 Lactosylceramide biosynthesis 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00399 Cap binding complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00293 DNA polymerase zeta complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00066 Lactosylceramide biosynthesis 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00297 DNA-PK complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00392 Ski complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00297 DNA-PK complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00103 Cholecalciferol biosynthesis 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 rno_M00399 Cap binding complex 1.00000000000991 9.90778393030779e-12 2 0 0 105 7176 M00682 Notch signaling 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 rno_M00340 Proteasome, 20S core particle 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 rno00120 Primary bile acid biosynthesis 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 ko00120 Primary bile acid biosynthesis 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 rno00450 Selenocompound metabolism 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 ko00450 Selenocompound metabolism 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 rno_M00682 Notch signaling 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 M00340 Proteasome, 20S core particle 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 rno_M00075 N-glycan biosynthesis, complex type 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 M00075 N-glycan biosynthesis, complex type 1.00000000001021 1.02095275045718e-11 16 0 0 105 7176 ko04917 Prolactin signaling pathway 1.00000000001027 1.0270252494589e-11 71 0 0 105 7176 rno04917 Prolactin signaling pathway 1.00000000001027 1.0270252494589e-11 71 0 0 105 7176 rno03460 Fanconi anemia pathway 1.0000000000105 1.05014039384064e-11 34 0 0 105 7176 ko03440 Homologous recombination 1.0000000000105 1.05014039384064e-11 34 0 0 105 7176 ko00591 Linoleic acid metabolism 1.0000000000105 1.05014039384064e-11 34 0 0 105 7176 rno00591 Linoleic acid metabolism 1.0000000000105 1.05014039384064e-11 34 0 0 105 7176 ko03460 Fanconi anemia pathway 1.0000000000105 1.05014039384064e-11 34 0 0 105 7176 rno03440 Homologous recombination 1.0000000000105 1.05014039384064e-11 34 0 0 105 7176 rno00910 Nitrogen metabolism 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 rno00531 Glycosaminoglycan degradation 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 ko00531 Glycosaminoglycan degradation 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 ko00360 Phenylalanine metabolism 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 rno_M00430 Exon junction complex (EJC) 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 ko00910 Nitrogen metabolism 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 ko00770 Pantothenate and CoA biosynthesis 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 rno00360 Phenylalanine metabolism 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 rno00770 Pantothenate and CoA biosynthesis 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 M00430 Exon junction complex (EJC) 1.00000000001122 1.12226199086225e-11 17 0 0 105 7176 ko00051 Fructose and mannose metabolism 1.00000000001122 1.12246178999061e-11 35 0 0 105 7176 rno00051 Fructose and mannose metabolism 1.00000000001122 1.12246178999061e-11 35 0 0 105 7176 ko03060 Protein export 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 rno04964 Proximal tubule bicarbonate reclamation 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 ko04320 Dorso-ventral axis formation 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 ko04964 Proximal tubule bicarbonate reclamation 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 rno04320 Dorso-ventral axis formation 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 rno03060 Protein export 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 rno00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1.00000000001125 1.12511316154511e-11 22 0 0 105 7176 rno05220 Chronic myeloid leukemia 1.0000000000113 1.13032505466505e-11 68 0 0 105 7176 ko05220 Chronic myeloid leukemia 1.0000000000113 1.13032505466505e-11 68 0 0 105 7176 rno00061 Fatty acid biosynthesis 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 ko00604 Glycosphingolipid biosynthesis - ganglio series 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno_M00295 BRCA1-associated genome surveillance complex (BASC) 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno_M00389 APC/C complex 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno00730 Thiamine metabolism 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 M00695 cAMP signaling 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 ko00730 Thiamine metabolism 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 ko00061 Fatty acid biosynthesis 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno00604 Glycosphingolipid biosynthesis - ganglio series 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno_M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 M00389 APC/C complex 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 M00295 BRCA1-associated genome surveillance complex (BASC) 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno_M00695 cAMP signaling 1.00000000001157 1.15672713865851e-11 14 0 0 105 7176 rno00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000001167 1.16694019750063e-11 28 0 0 105 7176 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000001167 1.16694019750063e-11 28 0 0 105 7176 rno00030 Pentose phosphate pathway 1.00000000001167 1.16694019750063e-11 28 0 0 105 7176 ko00030 Pentose phosphate pathway 1.00000000001167 1.16694019750063e-11 28 0 0 105 7176 ko00052 Galactose metabolism 1.00000000001167 1.16694019750063e-11 28 0 0 105 7176 rno00052 Galactose metabolism 1.00000000001167 1.16694019750063e-11 28 0 0 105 7176 ko03018 RNA degradation 1.00000000001169 1.16928680744859e-11 69 0 0 105 7176 rno03018 RNA degradation 1.00000000001169 1.16928680744859e-11 69 0 0 105 7176 ko04976 Bile secretion 1.00000000001169 1.16928680744859e-11 69 0 0 105 7176 rno04976 Bile secretion 1.00000000001169 1.16928680744859e-11 69 0 0 105 7176 ko04914 Progesterone-mediated oocyte maturation 1.00000000001185 1.1849684481839e-11 81 0 0 105 7176 rno04914 Progesterone-mediated oocyte maturation 1.00000000001185 1.1849684481839e-11 81 0 0 105 7176 ko04213 Longevity regulating pathway - multiple species 1.00000000001209 1.20908158331087e-11 60 0 0 105 7176 ko05211 Renal cell carcinoma 1.00000000001209 1.20908158331087e-11 60 0 0 105 7176 rno05211 Renal cell carcinoma 1.00000000001209 1.20908158331087e-11 60 0 0 105 7176 rno04213 Longevity regulating pathway - multiple species 1.00000000001209 1.20908158331087e-11 60 0 0 105 7176 ko05162 Measles 1.00000000001224 1.22377559009918e-11 119 0 0 105 7176 rno05162 Measles 1.00000000001224 1.22377559009918e-11 119 0 0 105 7176 rno00790 Folate biosynthesis 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno_M00676 PI3K-Akt signaling 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 M00002 Glycolysis, core module involving three-carbon compounds 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno_M00087 beta-Oxidation 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 M00676 PI3K-Akt signaling 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno00533 Glycosaminoglycan biosynthesis - keratan sulfate 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 M00055 N-glycan precursor biosynthesis 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 M00353 Spliceosome, Prp19/CDC5L complex 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 ko00790 Folate biosynthesis 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno_M00353 Spliceosome, Prp19/CDC5L complex 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno_M00055 N-glycan precursor biosynthesis 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno_M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 rno_M00002 Glycolysis, core module involving three-carbon compounds 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 M00087 beta-Oxidation 1.00000000001239 1.239170082737e-11 13 0 0 105 7176 ko04623 Cytosolic DNA-sensing pathway 1.00000000001239 1.23945408776129e-11 47 0 0 105 7176 ko05213 Endometrial cancer 1.00000000001239 1.23945408776129e-11 47 0 0 105 7176 rno04623 Cytosolic DNA-sensing pathway 1.00000000001239 1.23945408776129e-11 47 0 0 105 7176 rno05213 Endometrial cancer 1.00000000001239 1.23945408776129e-11 47 0 0 105 7176 rno00310 Lysine degradation 1.00000000001246 1.24557328454258e-11 48 0 0 105 7176 ko00510 N-Glycan biosynthesis 1.00000000001246 1.24557328454258e-11 48 0 0 105 7176 rno00510 N-Glycan biosynthesis 1.00000000001246 1.24557328454258e-11 48 0 0 105 7176 ko00310 Lysine degradation 1.00000000001246 1.24557328454258e-11 48 0 0 105 7176 rno_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 ko03430 Mismatch repair 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 rno00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 rno03430 Mismatch repair 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 ko00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 rno00900 Terpenoid backbone biosynthesis 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 ko00900 Terpenoid backbone biosynthesis 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 M00689 MAPK (p38) signaling 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 rno_M00689 MAPK (p38) signaling 1.00000000001311 1.31129901236045e-11 21 0 0 105 7176 rno00190 Oxidative phosphorylation 1.00000000001363 1.36273733239912e-11 114 0 0 105 7176 ko00190 Oxidative phosphorylation 1.00000000001363 1.36273733239912e-11 114 0 0 105 7176 ko04973 Carbohydrate digestion and absorption 1.00000000001381 1.38120296597304e-11 37 0 0 105 7176 rno04973 Carbohydrate digestion and absorption 1.00000000001381 1.38120296597304e-11 37 0 0 105 7176 M00382 SCF-FBS complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00380 SCF-BTRC complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00380 SCF-BTRC complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00405 THC complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00079 Keratan sulfate degradation 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00385 Cul4-DDB1-DDB2 complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00289 RF-C complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00382 SCF-FBS complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00079 Keratan sulfate degradation 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00386 Cul4-DDB1-CSA complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno00400 Phenylalanine, tyrosine and tryptophan biosynthesis 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00383 ECV complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00385 Cul4-DDB1-DDB2 complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00386 Cul4-DDB1-CSA complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00044 Tyrosine degradation, tyrosine => homogentisate 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00405 THC complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00383 ECV complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00044 Tyrosine degradation, tyrosine => homogentisate 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 M00289 RF-C complex 1.00000000001401 1.40117512224132e-11 5 0 0 105 7176 rno_M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 1.00000000001425 1.4252683720005e-11 36 0 0 105 7176 M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 1.00000000001425 1.4252683720005e-11 36 0 0 105 7176 rno_M00427 Nuclear pore complex 1.00000000001425 1.4252683720005e-11 36 0 0 105 7176 M00427 Nuclear pore complex 1.00000000001425 1.4252683720005e-11 36 0 0 105 7176 M00177 Ribosome, eukaryotes 1.00000000001446 1.44558714660472e-11 84 0 0 105 7176 rno04211 Longevity regulating pathway 1.00000000001446 1.44558714660472e-11 84 0 0 105 7176 rno_M00177 Ribosome, eukaryotes 1.00000000001446 1.44558714660472e-11 84 0 0 105 7176 rno00562 Inositol phosphate metabolism 1.00000000001471 1.47118413468481e-11 67 0 0 105 7176 ko00562 Inositol phosphate metabolism 1.00000000001471 1.47118413468481e-11 67 0 0 105 7176 M00009 Citrate cycle (TCA cycle, Krebs cycle) 1.00000000001506 1.50628909773752e-11 23 0 0 105 7176 M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate 1.00000000001506 1.50628909773752e-11 23 0 0 105 7176 rno_M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate 1.00000000001506 1.50628909773752e-11 23 0 0 105 7176 rno_M00009 Citrate cycle (TCA cycle, Krebs cycle) 1.00000000001506 1.50628909773752e-11 23 0 0 105 7176 ko01524 Platinum drug resistance 1.00000000001572 1.57180465532884e-11 75 0 0 105 7176 rno01524 Platinum drug resistance 1.00000000001572 1.57180465532884e-11 75 0 0 105 7176 ko00062 Fatty acid elongation 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno00062 Fatty acid elongation 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 M00354 Spliceosome, U4/U6.U5 tri-snRNP 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 ko00650 Butanoate metabolism 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno03020 RNA polymerase 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno_M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno00650 Butanoate metabolism 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno00053 Ascorbate and aldarate metabolism 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 ko03020 RNA polymerase 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 ko00053 Ascorbate and aldarate metabolism 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno_M00354 Spliceosome, U4/U6.U5 tri-snRNP 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 1.00000000001573 1.57289372277216e-11 26 0 0 105 7176 rno_M00285 MCM complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00073 N-glycan precursor trimming 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00424 Shelterin complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno00440 Phosphonate and phosphinate metabolism 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00284 Origin recognition complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00428 eIF4F complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00691 DNA damage-induced cell cycle checkpoints 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00428 eIF4F complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00398 Sm core complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00085 Fatty acid biosynthesis, elongation, mitochondria 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 ko00440 Phosphonate and phosphinate metabolism 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00047 Creatine pathway 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00073 N-glycan precursor trimming 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00284 Origin recognition complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00047 Creatine pathway 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00424 Shelterin complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00085 Fatty acid biosynthesis, elongation, mitochondria 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno00232 Caffeine metabolism 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00285 MCM complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00691 DNA damage-induced cell cycle checkpoints 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00398 Sm core complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 ko00232 Caffeine metabolism 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 M00413 FA core complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 rno_M00413 FA core complex 1.00000000001588 1.58783694980771e-11 6 0 0 105 7176 ko05212 Pancreatic cancer 1.00000000001617 1.61735554006153e-11 61 0 0 105 7176 ko04137 Mitophagy - animal 1.00000000001617 1.61735554006153e-11 61 0 0 105 7176 rno04137 Mitophagy - animal 1.00000000001617 1.61735554006153e-11 61 0 0 105 7176 rno05212 Pancreatic cancer 1.00000000001617 1.61735554006153e-11 61 0 0 105 7176 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1.0000000000163 1.63009390418443e-11 140 0 0 105 7176 rno04932 Non-alcoholic fatty liver disease (NAFLD) 1.0000000000163 1.63009390418443e-11 140 0 0 105 7176 ko04710 Circadian rhythm 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 rno00410 beta-Alanine metabolism 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 rno04710 Circadian rhythm 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 ko00410 beta-Alanine metabolism 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 ko00500 Starch and sucrose metabolism 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 rno00500 Starch and sucrose metabolism 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 ko04966 Collecting duct acid secretion 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 rno04966 Collecting duct acid secretion 1.00000000001672 1.67159671124098e-11 27 0 0 105 7176 rno04931 Insulin resistance 1.00000000001788 1.78750115181885e-11 105 0 0 105 7176 rno04978 Mineral absorption 1.0000000000181 1.80999304979208e-11 42 0 0 105 7176 ko04978 Mineral absorption 1.0000000000181 1.80999304979208e-11 42 0 0 105 7176 ko00970 Aminoacyl-tRNA biosynthesis 1.00000000001906 1.90581806498564e-11 41 0 0 105 7176 rno04962 Vasopressin-regulated water reabsorption 1.00000000001906 1.90581806498564e-11 41 0 0 105 7176 rno00970 Aminoacyl-tRNA biosynthesis 1.00000000001906 1.90581806498564e-11 41 0 0 105 7176 ko04962 Vasopressin-regulated water reabsorption 1.00000000001906 1.90581806498564e-11 41 0 0 105 7176 ko05210 Colorectal cancer 1.00000000001985 1.98477679126766e-11 57 0 0 105 7176 ko04622 RIG-I-like receptor signaling pathway 1.00000000001985 1.98477679126766e-11 57 0 0 105 7176 rno04622 RIG-I-like receptor signaling pathway 1.00000000001985 1.98477679126766e-11 57 0 0 105 7176 rno05210 Colorectal cancer 1.00000000001985 1.98477679126766e-11 57 0 0 105 7176 rno05160 Hepatitis C 1.00000000001987 1.98750727820442e-11 117 0 0 105 7176 ko05160 Hepatitis C 1.00000000001987 1.98750727820442e-11 117 0 0 105 7176 rno04380 Osteoclast differentiation 1.00000000002088 2.0875565343302e-11 118 0 0 105 7176 ko04380 Osteoclast differentiation 1.00000000002088 2.0875565343302e-11 118 0 0 105 7176 rno04630 Jak-STAT signaling pathway 1.00000000002093 2.09324293709424e-11 132 0 0 105 7176 ko04630 Jak-STAT signaling pathway 1.00000000002093 2.09324293709424e-11 132 0 0 105 7176 rno00240 Pyrimidine metabolism 1.00000000002125 2.12453770155335e-11 94 0 0 105 7176 ko00240 Pyrimidine metabolism 1.00000000002125 2.12453770155335e-11 94 0 0 105 7176 ko04140 Autophagy - animal 1.00000000002157 2.1566801739488e-11 125 0 0 105 7176 rno04140 Autophagy - animal 1.00000000002157 2.1566801739488e-11 125 0 0 105 7176 ko04933 AGE-RAGE signaling pathway in diabetic complications 1.00000000002224 2.22415060645416e-11 96 0 0 105 7176 rno04933 AGE-RAGE signaling pathway in diabetic complications 1.00000000002224 2.22415060645416e-11 96 0 0 105 7176 ko04120 Ubiquitin mediated proteolysis 1.00000000002251 2.25132583804451e-11 121 0 0 105 7176 rno04120 Ubiquitin mediated proteolysis 1.00000000002251 2.25132583804451e-11 121 0 0 105 7176 ko04110 Cell cycle 1.00000000002301 2.30146457171903e-11 115 0 0 105 7176 rno04110 Cell cycle 1.00000000002301 2.30146457171903e-11 115 0 0 105 7176 rno04621 NOD-like receptor signaling pathway 1.00000000002316 2.31592972089978e-11 137 0 0 105 7176 ko04621 NOD-like receptor signaling pathway 1.00000000002316 2.31592972089978e-11 137 0 0 105 7176 rno03008 Ribosome biogenesis in eukaryotes 1.00000000002333 2.33311836491134e-11 73 0 0 105 7176 ko03008 Ribosome biogenesis in eukaryotes 1.00000000002333 2.33311836491134e-11 73 0 0 105 7176 rno_M00089 Triacylglycerol biosynthesis 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 rno_M00686 Toll-like receptor signaling 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 M00099 Sphingosine biosynthesis 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 M00181 RNA polymerase III, eukaryotes 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 rno_M00181 RNA polymerase III, eukaryotes 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 rno_M00158 F-type ATPase, eukaryotes 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 M00089 Triacylglycerol biosynthesis 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 rno_M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 rno_M00099 Sphingosine biosynthesis 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 rno00603 Glycosphingolipid biosynthesis - globo and isoglobo series 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 M00158 F-type ATPase, eukaryotes 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 M00686 Toll-like receptor signaling 1.00000000002408 2.40806952961453e-11 15 0 0 105 7176 ko04142 Lysosome 1.00000000002503 2.50343530610835e-11 116 0 0 105 7176 rno04142 Lysosome 1.00000000002503 2.50343530610835e-11 116 0 0 105 7176 ko01522 Endocrine resistance 1.00000000002562 2.56228657222716e-11 88 0 0 105 7176 rno01522 Endocrine resistance 1.00000000002562 2.56228657222716e-11 88 0 0 105 7176 rno03010 Ribosome 1.00000000002622 2.62213072302361e-11 126 0 0 105 7176 ko03010 Ribosome 1.00000000002622 2.62213072302361e-11 126 0 0 105 7176 rno04141 Protein processing in endoplasmic reticulum 1.00000000002793 2.79345199843416e-11 155 0 0 105 7176 ko04141 Protein processing in endoplasmic reticulum 1.00000000002793 2.79345199843416e-11 155 0 0 105 7176 ko00230 Purine metabolism 1.00000000002828 2.82799872192127e-11 163 0 0 105 7176 rno00230 Purine metabolism 1.00000000002828 2.82799872192127e-11 163 0 0 105 7176 ko03013 RNA transport 1.00000000002868 2.86785940892481e-11 149 0 0 105 7176 rno03013 RNA transport 1.00000000002868 2.86785940892481e-11 149 0 0 105 7176