TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP276 Monoamine GPCRs 0.000477387799741072 -7.64718140001854 33 5 0.0769230769230769 65 3163 53949,24473,29413,79247,25324 Chrm5,Htr1a,Adra1d,Htr5b,Htr4 WP2811 mir219 in Oligodendrocyte Differentiation and Myelination 0.0107513569685403 -4.5327233027431 8 2 0.0307692307692308 65 3163 64619,29458 Zbtb18,Neurod1 WP473 GPCRs, Class A Rhodopsin-like 0.0142586347787162 -4.25039260639708 223 10 0.153846153846154 65 3163 25324,29413,84022,66024,54258,84348,24473,298944,25153,53949 Htr4,Adra1d,Ghsr,Npy2r,Cxcr1,Ackr3,Htr1a,Gpr22,Mas1,Chrm5 WP74 Integrin-mediated cell adhesion 0.0345929069650671 -3.36410661894366 89 5 0.0769230769230769 65 3163 311144,315744,25724,295378,81008 Itga4,Itga11,Itgb4,Vav3,Itga7 WP2433 Spinal Cord Injury 0.0423210658493011 -3.16247030627426 94 5 0.0769230769230769 65 3163 316539,65047,29221,24225,308565 Epha4,Slit1,Arg1,Bdnf,Klk8 WP271 Cytokines and Inflammatory Response (BioCarta) 0.0986065545068182 -2.31661754385458 26 2 0.0307692307692308 65 3163 294269,294270 RT1-Da,RT1-Db1 WP3887 Angiotensin signaling in thick ascending limbs 0.118519025216521 -2.13268178094339 29 2 0.0307692307692308 65 3163 25153,24681 Mas1,Prkcg WP1281 Hypothetical Network for Drug Addiction 0.132308643945514 -2.0226178740506 31 2 0.0307692307692308 65 3163 24409,50592 Grin2a,Gria1 WP303 Prostaglandin Synthesis and Regulation 0.139337399381862 -1.97085695338481 32 2 0.0307692307692308 65 3163 79242,29527 Hpgd,Ptgs2 WP131 Peptide GPCRs 0.143039731353573 -1.94463284567969 64 3 0.0461538461538462 65 3163 54258,84022,66024 Cxcr1,Ghsr,Npy2r WP326 Calcium Regulation in the Cardiac Cell 0.171943404561721 -1.7605898995611 144 5 0.0769230769230769 65 3163 689560,53949,24681,114705,29413 Ryr2,Chrm5,Prkcg,Rgs14,Adra1d WP2148 Brain derived neurotrophic factor 0.187745146655498 -1.67266983870931 10 1 0.0153846153846154 65 3163 24225 Bdnf WP2132 Serotonin and anxiety 0.236966553373216 -1.4398362728136 13 1 0.0153846153846154 65 3163 24473 Htr1a WP1280 Keap1-Nrf2 0.236966553373216 -1.4398362728136 13 1 0.0153846153846154 65 3163 24253 Cebpb WP133 Fatty Acid Omega Oxidation 0.236966553373216 -1.4398362728136 13 1 0.0153846153846154 65 3163 24188 Aldh1a1 WP270 Tryptophan metabolism 0.251378252863551 -1.3807964906904 47 2 0.0307692307692308 65 3163 25426,24188 Cyp1b1,Aldh1a1 WP155 Adipogenesis 0.267950565675676 -1.3169527719195 128 4 0.0615384615384615 65 3163 24253,79216,295691,246074 Cebpb,Gdf10,Frzb,Scd WP323 Biogenic Amine Synthesis 0.268136819865424 -1.31625790685733 15 1 0.0153846153846154 65 3163 24443 Hdc WP505 TGF Beta Signaling Pathway 0.274464619660926 -1.29293291646373 50 2 0.0307692307692308 65 3163 311071,445442 Zeb2,Thbs1 WP73 G Protein Signaling Pathways 0.275889993394746 -1.28775306737369 89 3 0.0461538461538462 65 3163 309242,293024,24681 Gna14,Akap13,Prkcg WP376 Renin - Angiotensin System 0.297534956711507 -1.21222355934794 53 2 0.0307692307692308 65 3163 50646,25153 Ptk2b,Mas1 WP1488 CFTR activity in the plasma membrane 0.298052565723727 -1.21048541298644 17 1 0.0153846153846154 65 3163 24681 Prkcg WP293 Eicosanoid Synthesis 0.31255561188669 -1.16297286760093 18 1 0.0153846153846154 65 3163 29527 Ptgs2 WP1302 Estrogen metabolism 0.31255561188669 -1.16297286760093 18 1 0.0153846153846154 65 3163 25426 Cyp1b1 WP564 Wnt Signaling Pathway 0.320508087175609 -1.13784776994254 56 2 0.0307692307692308 65 3163 24681,84426 Prkcg,Wnt4 WP504 Fatty Acid Biosynthesis 0.326763524520175 -1.11851853630096 19 1 0.0153846153846154 65 3163 246074 Scd WP153 Urea cycle and metabolism of amino groups 0.326763524520175 -1.11851853630096 19 1 0.0153846153846154 65 3163 29221 Arg1 WP351 Regulation of Actin Cytoskeleton 0.333652900031924 -1.09765404783177 142 4 0.0615384615384615 65 3163 25443,360854,84488,53949 Fgf10,Arpc5,Fgf13,Chrm5 WP442 Hypertrophy Model 0.340682217556395 -1.07680514952416 20 1 0.0153846153846154 65 3163 58853 Nr4a3 WP255 Blood Clotting Cascade 0.340682217556395 -1.07680514952416 20 1 0.0153846153846154 65 3163 306761 F12 WP1308 Endochondral Ossification 0.343312413734941 -1.06911441915203 59 2 0.0307692307692308 65 3163 295691,685781 Frzb,Ddr2 WP140 Myometrial Relaxation and Contraction Pathways 0.37173634749922 -0.98957041926791 150 4 0.0615384615384615 65 3163 689560,114705,84348,24681 Ryr2,Rgs14,Ackr3,Prkcg WP358 MAPK signaling pathway 0.386017249886088 -0.95187322169176 153 4 0.0615384615384615 65 3163 24681,59109,310738,24225 Prkcg,Ntrk1,Ngf,Bdnf WP1292 One Carbon Metabolism 0.406136335932314 -0.901066372960592 25 1 0.0153846153846154 65 3163 287379 Shmt1 WP656 p53 signal pathway 0.418437527188111 -0.871227678121325 26 1 0.0153846153846154 65 3163 292949 Perp WP409 GPCRs, Other 0.424551826269374 -0.856721192886908 70 2 0.0307692307692308 65 3163 29413,54258 Adra1d,Cxcr1 WP40 Inflammatory Response Pathway 0.44229205732562 -0.815784851932176 28 1 0.0153846153846154 65 3163 445442 Thbs1 WP5 EGFR1 Signaling Pathway 0.452012435368668 -0.794045587650766 167 4 0.0615384615384615 65 3163 50646,24253,295378,24681 Ptk2b,Cebpb,Vav3,Prkcg WP263 Ovarian Infertility Genes 0.45385537990108 -0.789976678160887 29 1 0.0153846153846154 65 3163 24253 Cebpb WP188 Focal Adhesion 0.475121441715198 -0.744184840855836 172 4 0.0615384615384615 65 3163 81008,445442,315744,311144 Itga7,Thbs1,Itga11,Itga4 WP94 Signaling of Hepatocyte Growth Factor Receptor 0.497794317942409 -0.69756830345206 33 1 0.0153846153846154 65 3163 50646 Ptk2b WP1290 Apoptosis 0.513635918218198 -0.666240594826206 83 2 0.0307692307692308 65 3163 29884,500592 Bok,Tnfrsf25 WP590 Cardiovascular Signaling 0.518439384108668 -0.656932164397988 35 1 0.0153846153846154 65 3163 81008 Itga7 WP1286 Metapathway biotransformation 0.520074236499407 -0.6537837150974 133 3 0.0461538461538462 65 3163 25426,291770,499302 Cyp1b1,Chst9,Gal3st3 WP1288 Wnt Signaling Pathway and Pluripotency 0.545482088520352 -0.606085309224532 88 2 0.0307692307692308 65 3163 84426,303586 Wnt4,Wnt9b WP1297 Retinol metabolism 0.557254373896905 -0.584733457672212 39 1 0.0153846153846154 65 3163 24188 Aldh1a1 WP1293 Selenium metabolism Selenoproteins 0.566466430780425 -0.568337457497701 40 1 0.0153846153846154 65 3163 499113 Selenov WP135 IL-6 Signaling Pathway 0.599152505304931 -0.51223911343044 97 2 0.0307692307692308 65 3163 50646,24253 Ptk2b,Cebpb WP655 p53 pathway 0.609770023412149 -0.494673403700975 45 1 0.0153846153846154 65 3163 292949 Perp WP375 Wnt Signaling Pathway NetPath 0.615979954201547 -0.484540857858722 100 2 0.0307692307692308 65 3163 84426,24681 Wnt4,Prkcg WP397 Id Signaling Pathway 0.648808164053458 -0.432618192947128 50 1 0.0153846153846154 65 3163 310738 Ngf WP547 Complement and Coagulation Cascades 0.703416006498005 -0.351806803304088 58 1 0.0153846153846154 65 3163 306761 F12 WP485 Alpha6-Beta4 Integrin Signaling Pathway 0.703416006498005 -0.351806803304088 58 1 0.0153846153846154 65 3163 25724 Itgb4 WP44 IL-5 Signaling Pathway 0.754897546339515 -0.281173239153782 67 1 0.0153846153846154 65 3163 50646 Ptk2b WP569 IL-2 Signaling Pathway 0.788758478412264 -0.237295116008874 74 1 0.0153846153846154 65 3163 50646 Ptk2b WP2376 NFE2L2 0.831458783208885 -0.18457355077933 153 2 0.0307692307692308 65 3163 24681,140727 Prkcg,Cacng6 WP59 Electron Transport Chain 0.832885029027022 -0.182859666716707 85 1 0.0153846153846154 65 3163 54315 Ucp2 WP1309 Toll-like receptor signaling pathway 0.843253529791168 -0.170487619112384 88 1 0.0153846153846154 65 3163 364867 Ticam2 WP529 mRNA processing 0.914051871458848 -0.0898679569951689 116 1 0.0153846153846154 65 3163 361859 Cdc40 WP1285 Arachidonate Epoxygenase Epoxide Hydrolase 0.999999999989271 -1.0728925671253e-11 4 0 0 65 3163 WP2541 Sulindac Metabolic Pathway 0.999999999989271 -1.0728925671253e-11 4 0 0 65 3163 WP1303 Polyol pathway 0.999999999989271 -1.0728925671253e-11 4 0 0 65 3163 WP305 Glucocorticoid Metabolism 0.999999999991655 -8.34488334516028e-12 6 0 0 65 3163 WP1300 Aflatoxin B1 metabolism 0.999999999991655 -8.34488334516028e-12 6 0 0 65 3163 WP360 Acetylcholine Synthesis 0.999999999991655 -8.34488334516028e-12 6 0 0 65 3163 WP1277 Non-homologous end joining 0.999999999991655 -8.34488334516028e-12 6 0 0 65 3163 WP418 Beta Oxidation of Unsaturated Fatty Acids 0.999999999991655 -8.34488334516028e-12 6 0 0 65 3163 WP282 Pentose Phosphate Pathway 0.999999999991655 -8.34488334516028e-12 6 0 0 65 3163 WP502 Nucleotide GPCRs 0.999999999994159 -5.84118686647574e-12 12 0 0 65 3163 WP1296 Homologous recombination 0.999999999994159 -5.84118686647574e-12 12 0 0 65 3163 WP104 Alanine and aspartate metabolism 0.999999999994159 -5.84118686647574e-12 12 0 0 65 3163 WP1485 Interactions between CFTR and other ion channels 0.99999999999416 -5.84015727304602e-12 5 0 0 65 3163 WP513 Catecholamine synthesis 0.99999999999416 -5.84015727304602e-12 5 0 0 65 3163 WP349 Synthesis and Degradation of Ketone Bodies 0.99999999999416 -5.84015727304602e-12 5 0 0 65 3163 WP124 Irinotecan Pathway 0.99999999999446 -5.54004839679101e-12 21 0 0 65 3163 WP1276 Glucuronidation 0.99999999999446 -5.54004839679101e-12 21 0 0 65 3163 WP469 Glutathione metabolism 0.99999999999446 -5.54004839679101e-12 21 0 0 65 3163 WP1294 NLR Proteins 0.999999999994607 -5.39344453964044e-12 8 0 0 65 3163 WP1282 Methylation 0.999999999994607 -5.39344453964044e-12 8 0 0 65 3163 WP86 Heme Biosynthesis 0.999999999994954 -5.04568363349048e-12 9 0 0 65 3163 WP557 ACE Inhibitor Pathway 0.999999999994954 -5.04568363349048e-12 9 0 0 65 3163 WP3894 Fructose Metabolism in Proximal Tubules 0.999999999994966 -5.03387835570913e-12 18 0 0 65 3163 WP487 Apoptosis Modulation by HSP70 0.999999999994966 -5.03387835570913e-12 18 0 0 65 3163 WP145 Statin Pathway 0.999999999994966 -5.03387835570913e-12 18 0 0 65 3163 WP446 MAPK Cascade 0.999999999995317 -4.68292260955297e-12 28 0 0 65 3163 WP278 Matrix Metalloproteinases 0.999999999995317 -4.68292260955297e-12 28 0 0 65 3163 WP419 Mitochondrial LC-Fatty Acid Beta-Oxidation 0.999999999995534 -4.46639822187868e-12 16 0 0 65 3163 WP1278 EBV LMP1 signaling 0.999999999995534 -4.46639822187868e-12 16 0 0 65 3163 WP3882 Thick Ascending Limb Transporters 0.999999999996055 -3.94508921748458e-12 11 0 0 65 3163 WP1287 Amino acid conjugation of benzoic acid 0.999999999997091 -2.9085441195266e-12 2 0 0 65 3163 WP3650 Acetate mediated promotion of metabolic syndrome 0.999999999997091 -2.9085441195266e-12 2 0 0 65 3163 WP1964 VEGFR-3 signaling 0.999999999998094 -1.90628680021664e-12 13 0 0 65 3163 WP1312 Signal Transduction of S1P 0.999999999998119 -1.88136113364824e-12 24 0 0 65 3163 WP1311 Folic Acid Network 0.999999999998119 -1.88136113364824e-12 24 0 0 65 3163 WP372 Beta Oxidation Meta Pathway 0.999999999998272 -1.7276839877812e-12 32 0 0 65 3163 WP139 Nuclear receptors in lipid metabolism and toxicity 0.999999999998272 -1.7276839877812e-12 32 0 0 65 3163 WP1301 Mitochondrial Gene Expression 0.999999999998426 -1.57374070958392e-12 19 0 0 65 3163 WP161 Small Ligand GPCRs 0.999999999998426 -1.57374070958392e-12 19 0 0 65 3163 WP574 Hedgehog Signaling Pathway 0.999999999998466 -1.53417952593749e-12 20 0 0 65 3163 WP654 ATM Signaling Pathway 0.999999999998525 -1.47534473549677e-12 26 0 0 65 3163 WP347 TCA Cycle 0.999999999998525 -1.47534473549677e-12 26 0 0 65 3163 WP1968 Genetic alterations of lung cancer 0.999999999998525 -1.47534473549677e-12 26 0 0 65 3163 WP1284 EPO Receptor Signaling 0.999999999998525 -1.47534473549677e-12 26 0 0 65 3163 WP1307 Fatty Acid Beta Oxidation 0.999999999998593 -1.40708599059804e-12 34 0 0 65 3163 WP517 Notch Signaling Pathway 0.999999999998593 -1.40708599059804e-12 34 0 0 65 3163 WP294 p38 MAPK Signaling Pathway (BioCarta) 0.999999999998593 -1.40708599059804e-12 34 0 0 65 3163 WP1289 Type II interferon signaling (IFNG) 0.999999999998593 -1.40708599059804e-12 34 0 0 65 3163 WP173 Oxidative Stress 0.999999999998593 -1.40708599059804e-12 34 0 0 65 3163 WP42 GPCRs, Class C Metabotropic glutamate, pheromone 0.999999999998646 -1.3545091846593e-12 15 0 0 65 3163 WP461 Cholesterol Biosynthesis 0.999999999998646 -1.3545091846593e-12 15 0 0 65 3163 WP81 Complement Activation, Classical Pathway 0.9999999999987 -1.29985569800021e-12 14 0 0 65 3163 WP489 Osteoclast 0.9999999999987 -1.29985569800021e-12 14 0 0 65 3163 WP160 Glycogen Metabolism 0.999999999998721 -1.2788029512718e-12 33 0 0 65 3163 WP1295 Mismatch repair 0.999999999999288 -7.11570510762373e-13 7 0 0 65 3163 WP508 Biosynthesis of Aldosterone and Cortisol 0.999999999999288 -7.11570510762373e-13 7 0 0 65 3163 WP1291 Phase I biotransformations, non P450 0.999999999999288 -7.11570510762373e-13 7 0 0 65 3163 WP3649 Wnt myofibroblastic activation of Hepatic Stellate Cells 0.999999999999418 -5.81503986605311e-13 3 0 0 65 3163 WP1310 Selenium Micronutrient Network 0.999999999999432 -5.68162097703464e-13 22 0 0 65 3163 WP378 GPCRs, Class B Secretin-like 0.999999999999432 -5.68162097703464e-13 22 0 0 65 3163 WP66 Steroid Biosynthesis 0.999999999999954 -4.62223627954977e-14 10 0 0 65 3163 WP227 Osteoblast 0.999999999999954 -4.62223627954977e-14 10 0 0 65 3163 WP1487 TNF-alpha and mucus production in lung epythelium 0.999999999999974 -2.5701236364142e-14 23 0 0 65 3163 WP632 Cholesterol metabolism 0.999999999999974 -2.5701236364142e-14 23 0 0 65 3163 WP146 Nucleotide Metabolism 1.00000000000032 3.19221943344302e-13 17 0 0 65 3163 WP8 IL-9 Signaling Pathway 1.00000000000053 5.33369528224444e-13 25 0 0 65 3163 WP1965 VEGF-receptor Signal Transduction 1.00000000000053 5.33369528224444e-13 25 0 0 65 3163 WP3901 Lipid Droplet Metabolism 1.00000000000053 5.33369528224444e-13 25 0 0 65 3163 WP520 G13 Signaling Pathway 1.00000000000055 5.53558409460543e-13 37 0 0 65 3163 WP491 Eukaryotic Transcription Initiation 1.00000000000055 5.53558409460543e-13 37 0 0 65 3163 WP1299 ErbB signaling pathway 1.00000000000069 6.93097516918388e-13 46 0 0 65 3163 WP149 Translation Factors 1.00000000000095 9.47855236793667e-13 44 0 0 65 3163 WP337 Glycolysis and Gluconeogenesis 1.0000000000024 2.39871939496383e-12 42 0 0 65 3163 WP316 Striated Muscle Contraction 1.00000000000313 3.13015246126892e-12 36 0 0 65 3163 WP217 Nuclear Receptors 1.00000000000313 3.13015246126892e-12 36 0 0 65 3163 WP355 IL-1 Signaling Pathway 1.00000000000313 3.13015246126892e-12 36 0 0 65 3163 WP89 FAS pathway and Stress induction of HSP regulation 1.00000000000379 3.79431640198484e-12 35 0 0 65 3163 WP302 Proteasome Degradation 1.0000000000051 5.10101116918988e-12 59 0 0 65 3163 WP2562 Relationship between glutathione and NADPH 1.00000000000534 5.33813147017489e-12 57 0 0 65 3163 WP1283 Oxidative phosphorylation 1.00000000000624 6.24102042498841e-12 47 0 0 65 3163 WP147 Kit Receptor Signaling Pathway 1.0000000000069 6.89742034022637e-12 65 0 0 65 3163 WP1279 Estrogen signaling 1.00000000000706 7.06205237129162e-12 63 0 0 65 3163 WP348 G1 to S cell cycle control 1.00000000000706 7.06205237129162e-12 63 0 0 65 3163 WP3916 Hexoses metabolism in proximal tubules 1.00000000000757 7.57043264438368e-12 55 0 0 65 3163 WP3881 Proximal Tubule Transporters 1.00000000000757 7.57043264438368e-12 55 0 0 65 3163 WP484 DNA Replication 1.00000000000862 8.6174316252243e-12 40 0 0 65 3163 WP2042 PKA-HCG-Glycogen Syntase 1.00000000000862 8.6174316252243e-12 40 0 0 65 3163 WP319 IL-3 Signaling Pathway 1.00000000000914 9.1416655349411e-12 99 0 0 65 3163 WP30 Cytoplasmic Ribosomal Proteins 1.00000000001173 1.17282357018745e-11 76 0 0 65 3163 WP199 Delta-Notch Signaling Pathway 1.00000000001222 1.2215271390941e-11 73 0 0 65 3163 WP439 Insulin Signaling 1.00000000001249 1.24869893532916e-11 150 0 0 65 3163 WP429 Cell cycle 1.00000000001293 1.29287502030712e-11 81 0 0 65 3163 WP457 TNF-alpha NF-kB Signaling Pathway 1.0000000000205 2.0498349015246e-11 166 0 0 65 3163