TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols rno04080 Neuroactive ligand-receptor interaction 2.99326496215869e-10 -21.929486177705 284 17 0.261538461538462 65 7176 24925,24316,24947,25101,24808,24318,58959,64680,366274,298521,60590,191573,29335,25706,25083,24173,24417 Adrb1,Drd1,Gabra3,Chrna3,Tacr3,Drd2,Crhr1,Crhr2,Ntsr1,Grik3,Grm8,Grin3a,Oprk1,Cckbr,Adra2a,Adra1b,Grm4 ko04080 Neuroactive ligand-receptor interaction 2.99326496215869e-10 -21.929486177705 284 17 0.261538461538462 65 7176 298521,366274,60590,24925,24947,24316,24318,64680,58959,24808,25101,25706,24173,25083,24417,29335,191573 Grik3,Ntsr1,Grm8,Adrb1,Gabra3,Drd1,Drd2,Crhr2,Crhr1,Tacr3,Chrna3,Cckbr,Adra1b,Adra2a,Grm4,Oprk1,Grin3a ko05030 Cocaine addiction 3.50643823824567e-06 -12.5609097826293 47 6 0.0923076923076923 65 7176 24316,24311,25085,24318,191573,29481 Drd1,Ddc,Th,Drd2,Grin3a,Rgs9 rno05030 Cocaine addiction 3.50643823824567e-06 -12.5609097826293 47 6 0.0923076923076923 65 7176 191573,29481,24316,24311,24318,25085 Grin3a,Rgs9,Drd1,Ddc,Drd2,Th ko04020 Calcium signaling pathway 2.56629546360064e-05 -10.570462059809 176 9 0.138461538461538 65 7176 24925,296369,24316,24808,25706,24173,366274,140448,24246 Adrb1,Tnnc2,Drd1,Tacr3,Cckbr,Adra1b,Ntsr1,Slc8a3,Camk2d rno04020 Calcium signaling pathway 2.56629546360064e-05 -10.570462059809 176 9 0.138461538461538 65 7176 25706,24246,366274,24173,140448,24925,24808,296369,24316 Cckbr,Camk2d,Ntsr1,Adra1b,Slc8a3,Adrb1,Tacr3,Tnnc2,Drd1 ko05031 Amphetamine addiction 0.000244586206466464 -8.31594272850709 63 5 0.0769230769230769 65 7176 191573,24316,24311,24246,25085 Grin3a,Drd1,Ddc,Camk2d,Th rno05031 Amphetamine addiction 0.000244586206466464 -8.31594272850709 63 5 0.0769230769230769 65 7176 24316,24311,24246,25085,191573 Drd1,Ddc,Camk2d,Th,Grin3a rno04022 cGMP-PKG signaling pathway 0.000503937755762562 -7.59305779799082 157 7 0.107692307692308 65 7176 497757,29557,140448,25083,24173,24925,25523 Gucy1a1,Myh7,Slc8a3,Adra2a,Adra1b,Adrb1,Prkg2 ko04022 cGMP-PKG signaling pathway 0.000503937755762562 -7.59305779799082 157 7 0.107692307692308 65 7176 497757,29557,25083,24173,140448,25523,24925 Gucy1a1,Myh7,Adra2a,Adra1b,Slc8a3,Prkg2,Adrb1 ko04360 Axon guidance 0.000608291654190824 -7.40485609662188 162 7 0.107692307692308 65 7176 24246,246217,29499,306636,29751,315996,116683 Camk2d,Ngef,Shh,Efnb2,Sema3a,Sema3f,Efna5 rno04360 Axon guidance 0.000608291654190824 -7.40485609662188 162 7 0.107692307692308 65 7176 24246,246217,29499,306636,29751,315996,116683 Camk2d,Ngef,Shh,Efnb2,Sema3a,Sema3f,Efna5 rno_M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 0.000793859658212067 -7.1386038652213 5 2 0.0307692307692308 65 7176 24311,25085 Ddc,Th M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline 0.000793859658212067 -7.1386038652213 5 2 0.0307692307692308 65 7176 24311,25085 Ddc,Th rno05034 Alcoholism 0.000846908765248641 -7.07391758428671 124 6 0.0923076923076923 65 7176 191573,60449,25085,24318,24311,24316 Grin3a,Gnb3,Th,Drd2,Ddc,Drd1 ko04728 Dopaminergic synapse 0.000846908765248641 -7.07391758428671 124 6 0.0923076923076923 65 7176 25085,24318,24311,24246,24316,60449 Th,Drd2,Ddc,Camk2d,Drd1,Gnb3 rno04728 Dopaminergic synapse 0.000846908765248641 -7.07391758428671 124 6 0.0923076923076923 65 7176 60449,24311,24246,25085,24318,24316 Gnb3,Ddc,Camk2d,Th,Drd2,Drd1 ko05034 Alcoholism 0.000846908765248641 -7.07391758428671 124 6 0.0923076923076923 65 7176 191573,60449,24311,24318,25085,24316 Grin3a,Gnb3,Ddc,Drd2,Th,Drd1 rno04540 Gap junction 0.000928348727173199 -6.98210311217523 84 5 0.0769230769230769 65 7176 24925,25523,24318,497757,24316 Adrb1,Prkg2,Drd2,Gucy1a1,Drd1 ko04540 Gap junction 0.000928348727173199 -6.98210311217523 84 5 0.0769230769230769 65 7176 24318,497757,24316,25523,24925 Drd2,Gucy1a1,Drd1,Prkg2,Adrb1 rno04024 cAMP signaling pathway 0.00141601215625359 -6.55991069882261 187 7 0.107692307692308 65 7176 24316,24246,140589,24318,24255,24925,191573 Drd1,Camk2d,Gli1,Drd2,Cftr,Adrb1,Grin3a ko04024 cAMP signaling pathway 0.00141601215625359 -6.55991069882261 187 7 0.107692307692308 65 7176 24246,24318,140589,24316,191573,24255,24925 Camk2d,Drd2,Gli1,Drd1,Grin3a,Cftr,Adrb1 rno04261 Adrenergic signaling in cardiomyocytes 0.00142237519864129 -6.55542712963245 137 6 0.0923076923076923 65 7176 24925,24173,25665,300992,29557,24246 Adrb1,Adra1b,Scn5a,Cacna2d2,Myh7,Camk2d ko04261 Adrenergic signaling in cardiomyocytes 0.00142237519864129 -6.55542712963245 137 6 0.0923076923076923 65 7176 24173,25665,300992,24246,29557,24925 Adra1b,Scn5a,Cacna2d2,Camk2d,Myh7,Adrb1 ko04724 Glutamatergic synapse 0.00272551871508639 -5.90509651482184 107 5 0.0769230769230769 65 7176 298521,24417,60590,60449,191573 Grik3,Grm4,Grm8,Gnb3,Grin3a rno04724 Glutamatergic synapse 0.00272551871508639 -5.90509651482184 107 5 0.0769230769230769 65 7176 60449,191573,298521,60590,24417 Gnb3,Grin3a,Grik3,Grm8,Grm4 rno_M00678 Hedgehog signaling 0.0034693381144983 -5.66379144831888 10 2 0.0307692307692308 65 7176 140589,29499 Gli1,Shh M00678 Hedgehog signaling 0.0034693381144983 -5.66379144831888 10 2 0.0307692307692308 65 7176 29499,140589 Shh,Gli1 rno04970 Salivary secretion 0.003977318114891 -5.52714752729798 72 4 0.0615384615384615 65 7176 25523,24925,24173,497757 Prkg2,Adrb1,Adra1b,Gucy1a1 ko04970 Salivary secretion 0.003977318114891 -5.52714752729798 72 4 0.0615384615384615 65 7176 497757,24173,25523,24925 Gucy1a1,Adra1b,Prkg2,Adrb1 rno04713 Circadian entrainment 0.008751833470791 -4.73849206104398 90 4 0.0615384615384615 65 7176 60449,25523,497757,24246 Gnb3,Prkg2,Gucy1a1,Camk2d ko04713 Circadian entrainment 0.008751833470791 -4.73849206104398 90 4 0.0615384615384615 65 7176 60449,25523,24246,497757 Gnb3,Prkg2,Camk2d,Gucy1a1 rno05217 Basal cell carcinoma 0.0114309198825439 -4.4714333247511 52 3 0.0461538461538462 65 7176 29499,29373,140589 Shh,Bmp2,Gli1 ko05217 Basal cell carcinoma 0.0114309198825439 -4.4714333247511 52 3 0.0461538461538462 65 7176 29499,29373,140589 Shh,Bmp2,Gli1 ko04730 Long-term depression 0.0133119863209217 -4.3190904224788 55 3 0.0461538461538462 65 7176 25523,58959,497757 Prkg2,Crhr1,Gucy1a1 rno04730 Long-term depression 0.0133119863209217 -4.3190904224788 55 3 0.0461538461538462 65 7176 25523,497757,58959 Prkg2,Gucy1a1,Crhr1 rno04725 Cholinergic synapse 0.0152849341055725 -4.18088763470048 106 4 0.0615384615384615 65 7176 85426,60449,25101,24246 Slc5a7,Gnb3,Chrna3,Camk2d ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0.0166077485583261 -4.09788591190577 22 2 0.0307692307692308 65 7176 293451,294449 Hs3st2,Hs3st5 rno00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 0.0166077485583261 -4.09788591190577 22 2 0.0307692307692308 65 7176 294449,293451 Hs3st5,Hs3st2 ko04744 Phototransduction 0.0196144109046766 -3.9314907326711 24 2 0.0307692307692308 65 7176 56814,29481 Slc24a1,Rgs9 rno04744 Phototransduction 0.0196144109046766 -3.9314907326711 24 2 0.0307692307692308 65 7176 29481,56814 Rgs9,Slc24a1 ko04924 Renin secretion 0.0225179382868348 -3.7934430302198 67 3 0.0461538461538462 65 7176 497757,24925,25523 Gucy1a1,Adrb1,Prkg2 rno04924 Renin secretion 0.0225179382868348 -3.7934430302198 67 3 0.0461538461538462 65 7176 25523,24925,497757 Prkg2,Adrb1,Gucy1a1 ko04971 Gastric acid secretion 0.0252448628395631 -3.6791325958584 70 3 0.0461538461538462 65 7176 24246,24255,25706 Camk2d,Cftr,Cckbr rno04971 Gastric acid secretion 0.0252448628395631 -3.6791325958584 70 3 0.0461538461538462 65 7176 24246,24255,25706 Camk2d,Cftr,Cckbr ko05414 Dilated cardiomyopathy 0.0344468304374081 -3.36833829047481 79 3 0.0461538461538462 65 7176 29557,300992,24925 Myh7,Cacna2d2,Adrb1 rno05414 Dilated cardiomyopathy 0.0344468304374081 -3.36833829047481 79 3 0.0461538461538462 65 7176 24925,300992,29557 Adrb1,Cacna2d2,Myh7 ko00350 Tyrosine metabolism 0.0356235293209208 -3.33474892346522 33 2 0.0307692307692308 65 7176 25085,24311 Th,Ddc rno00350 Tyrosine metabolism 0.0356235293209208 -3.33474892346522 33 2 0.0307692307692308 65 7176 24311,25085 Ddc,Th rno04742 Taste transduction 0.039023746437673 -3.24358493512929 83 3 0.0461538461538462 65 7176 60449,24947,24417 Gnb3,Gabra3,Grm4 ko04742 Taste transduction 0.039023746437673 -3.24358493512929 83 3 0.0461538461538462 65 7176 24417,24947,60449 Grm4,Gabra3,Gnb3 rno05200 Pathways in cancer 0.0410383094857444 -3.19324927083586 356 7 0.107692307692308 65 7176 60449,192362,54355,361714,29499,140589,29373 Gnb3,Lamc2,Rassf5,Rasgrp2,Shh,Gli1,Bmp2 rno_M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 0.0444889613286869 -3.11251418061143 5 1 0.0153846153846154 65 7176 24311 Ddc M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin 0.0444889613286869 -3.11251418061143 5 1 0.0153846153846154 65 7176 24311 Ddc rno05032 Morphine addiction 0.0451592109419211 -3.09756101235285 88 3 0.0461538461538462 65 7176 24947,24316,60449 Gabra3,Drd1,Gnb3 ko05032 Morphine addiction 0.0451592109419211 -3.09756101235285 88 3 0.0461538461538462 65 7176 24316,24947,60449 Drd1,Gabra3,Gnb3 rno04216 Ferroptosis 0.0460874688641195 -3.07721419100399 38 2 0.0307692307692308 65 7176 29292,81639 Ftl1,Alox15 ko04216 Ferroptosis 0.0460874688641195 -3.07721419100399 38 2 0.0307692307692308 65 7176 81639,29292 Alox15,Ftl1 rno04340 Hedgehog signaling pathway 0.048300963668601 -3.03030376679177 39 2 0.0307692307692308 65 7176 29499,140589 Shh,Gli1 ko04340 Hedgehog signaling pathway 0.048300963668601 -3.03030376679177 39 2 0.0307692307692308 65 7176 140589,29499 Gli1,Shh rno05033 Nicotine addiction 0.0505526551051432 -2.98473981055984 40 2 0.0307692307692308 65 7176 24947,191573 Gabra3,Grin3a ko05033 Nicotine addiction 0.0505526551051432 -2.98473981055984 40 2 0.0307692307692308 65 7176 24947,191573 Gabra3,Grin3a M00029 Urea cycle 0.0531499873385894 -2.93463741241454 6 1 0.0153846153846154 65 7176 25698 Ass1 rno_M00029 Urea cycle 0.0531499873385894 -2.93463741241454 6 1 0.0153846153846154 65 7176 25698 Ass1 M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 0.0786719228919274 -2.54246894843395 9 1 0.0153846153846154 65 7176 282636 Impa2 rno_M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol 0.0786719228919274 -2.54246894843395 9 1 0.0153846153846154 65 7176 282636 Impa2 rno04611 Platelet activation 0.0823688889302743 -2.49654747488681 113 3 0.0461538461538462 65 7176 25523,361714,497757 Prkg2,Rasgrp2,Gucy1a1 rno04726 Serotonergic synapse 0.0823688889302743 -2.49654747488681 113 3 0.0461538461538462 65 7176 81639,60449,24311 Alox15,Gnb3,Ddc rno04923 Regulation of lipolysis in adipocytes 0.0829296811944715 -2.48976224479904 53 2 0.0307692307692308 65 7176 25523,24925 Prkg2,Adrb1 M00694 cGMP signaling 0.087027765646052 -2.44152806588668 10 1 0.0153846153846154 65 7176 497757 Gucy1a1 rno_M00694 cGMP signaling 0.087027765646052 -2.44152806588668 10 1 0.0153846153846154 65 7176 497757 Gucy1a1 rno05012 Parkinson's disease 0.0982048694974154 -2.32069947730108 122 3 0.0461538461538462 65 7176 24318,25085,24316 Drd2,Th,Drd1 ko04015 Rap1 signaling pathway 0.104043486247424 -2.26294633024122 198 4 0.0615384615384615 65 7176 24318,116683,361714,54355 Drd2,Efna5,Rasgrp2,Rassf5 rno04015 Rap1 signaling pathway 0.104043486247424 -2.26294633024122 198 4 0.0615384615384615 65 7176 116683,54355,361714,24318 Efna5,Rassf5,Rasgrp2,Drd2 ko04512 ECM-receptor interaction 0.105257095073998 -2.25134939706228 61 2 0.0307692307692308 65 7176 25460,192362 Hmmr,Lamc2 rno04512 ECM-receptor interaction 0.105257095073998 -2.25134939706228 61 2 0.0307692307692308 65 7176 25460,192362 Hmmr,Lamc2 rno04014 Ras signaling pathway 0.125081488904604 -2.07878984284483 212 4 0.0615384615384615 65 7176 54355,361714,116683,60449 Rassf5,Rasgrp2,Efna5,Gnb3 ko04921 Oxytocin signaling pathway 0.133183366553448 -2.01602840439833 140 3 0.0461538461538462 65 7176 300992,497757,24246 Cacna2d2,Gucy1a1,Camk2d rno04921 Oxytocin signaling pathway 0.133183366553448 -2.01602840439833 140 3 0.0461538461538462 65 7176 24246,497757,300992 Camk2d,Gucy1a1,Cacna2d2 ko04260 Cardiac muscle contraction 0.135117671977075 -2.00160923593034 71 2 0.0307692307692308 65 7176 300992,29557 Cacna2d2,Myh7 rno04260 Cardiac muscle contraction 0.135117671977075 -2.00160923593034 71 2 0.0307692307692308 65 7176 300992,29557 Cacna2d2,Myh7 ko00360 Phenylalanine metabolism 0.143465472033565 -1.94166088574093 17 1 0.0153846153846154 65 7176 24311 Ddc rno00360 Phenylalanine metabolism 0.143465472033565 -1.94166088574093 17 1 0.0153846153846154 65 7176 24311 Ddc rno05410 Hypertrophic cardiomyopathy (HCM) 0.150692373771186 -1.89251477999723 76 2 0.0307692307692308 65 7176 29557,300992 Myh7,Cacna2d2 ko05410 Hypertrophic cardiomyopathy (HCM) 0.150692373771186 -1.89251477999723 76 2 0.0307692307692308 65 7176 300992,29557 Cacna2d2,Myh7 ko00511 Other glycan degradation 0.151242360471209 -1.88887169262809 18 1 0.0153846153846154 65 7176 29204 Neu2 rno_M00679 BMP signaling 0.151242360471209 -1.88887169262809 18 1 0.0153846153846154 65 7176 29373 Bmp2 rno00511 Other glycan degradation 0.151242360471209 -1.88887169262809 18 1 0.0153846153846154 65 7176 29204 Neu2 M00679 BMP signaling 0.151242360471209 -1.88887169262809 18 1 0.0153846153846154 65 7176 29373 Bmp2 rno00220 Arginine biosynthesis 0.158949715398568 -1.8391673821361 19 1 0.0153846153846154 65 7176 25698 Ass1 ko00220 Arginine biosynthesis 0.158949715398568 -1.8391673821361 19 1 0.0153846153846154 65 7176 25698 Ass1 rno04925 Aldosterone synthesis and secretion 0.163401083710138 -1.81154746432524 80 2 0.0307692307692308 65 7176 29553,24246 Kcnk3,Camk2d ko04925 Aldosterone synthesis and secretion 0.163401083710138 -1.81154746432524 80 2 0.0307692307692308 65 7176 24246,29553 Camk2d,Kcnk3 ko00340 Histidine metabolism 0.174158267718121 -1.74779080860209 21 1 0.0153846153846154 65 7176 24311 Ddc rno00340 Histidine metabolism 0.174158267718121 -1.74779080860209 21 1 0.0153846153846154 65 7176 24311 Ddc ko04727 GABAergic synapse 0.179547468288647 -1.71731565872331 85 2 0.0307692307692308 65 7176 60449,24947 Gnb3,Gabra3 rno04727 GABAergic synapse 0.179547468288647 -1.71731565872331 85 2 0.0307692307692308 65 7176 24947,60449 Gabra3,Gnb3 ko04922 Glucagon signaling pathway 0.202539029132761 -1.59682267454875 92 2 0.0307692307692308 65 7176 24246,25756 Camk2d,Cpt1b rno04922 Glucagon signaling pathway 0.202539029132761 -1.59682267454875 92 2 0.0307692307692308 65 7176 24246,25756 Camk2d,Cpt1b ko04723 Retrograde endocannabinoid signaling 0.222509694921028 -1.50278460564633 98 2 0.0307692307692308 65 7176 60449,24947 Gnb3,Gabra3 rno04723 Retrograde endocannabinoid signaling 0.222509694921028 -1.50278460564633 98 2 0.0307692307692308 65 7176 24947,60449 Gabra3,Gnb3 ko04750 Inflammatory mediator regulation of TRP channels 0.242639364218017 -1.41617903587388 104 2 0.0307692307692308 65 7176 63882,24246 Asic4,Camk2d rno04750 Inflammatory mediator regulation of TRP channels 0.242639364218017 -1.41617903587388 104 2 0.0307692307692308 65 7176 63882,24246 Asic4,Camk2d ko00250 Alanine, aspartate and glutamate metabolism 0.246231936641938 -1.40148135535878 31 1 0.0153846153846154 65 7176 25698 Ass1 rno00250 Alanine, aspartate and glutamate metabolism 0.246231936641938 -1.40148135535878 31 1 0.0153846153846154 65 7176 25698 Ass1 ko00591 Linoleic acid metabolism 0.266619882159778 -1.32193129727488 34 1 0.0153846153846154 65 7176 81639 Alox15 rno00591 Linoleic acid metabolism 0.266619882159778 -1.32193129727488 34 1 0.0153846153846154 65 7176 81639 Alox15 ko04270 Vascular smooth muscle contraction 0.272976394057332 -1.29836995619027 113 2 0.0307692307692308 65 7176 497757,24173 Gucy1a1,Adra1b rno04270 Vascular smooth muscle contraction 0.272976394057332 -1.29836995619027 113 2 0.0307692307692308 65 7176 497757,24173 Gucy1a1,Adra1b ko04152 AMPK signaling pathway 0.286465681645048 -1.25013653483616 117 2 0.0307692307692308 65 7176 24255,25756 Cftr,Cpt1b rno04152 AMPK signaling pathway 0.286465681645048 -1.25013653483616 117 2 0.0307692307692308 65 7176 25756,24255 Cpt1b,Cftr ko00565 Ether lipid metabolism 0.299399741469936 -1.20597567049085 39 1 0.0153846153846154 65 7176 114113 Pafah1b3 rno00565 Ether lipid metabolism 0.299399741469936 -1.20597567049085 39 1 0.0153846153846154 65 7176 114113 Pafah1b3 rno02010 ABC transporters 0.30578043599161 -1.18488796401639 40 1 0.0153846153846154 65 7176 24255 Cftr ko02010 ABC transporters 0.30578043599161 -1.18488796401639 40 1 0.0153846153846154 65 7176 24255 Cftr rno04371 Apelin signaling pathway 0.316718158160105 -1.14974299155825 126 2 0.0307692307692308 65 7176 60449,140448 Gnb3,Slc8a3 ko04978 Mineral absorption 0.318370652447073 -1.14453900122272 42 1 0.0153846153846154 65 7176 29292 Ftl1 rno00380 Tryptophan metabolism 0.318370652447073 -1.14453900122272 42 1 0.0153846153846154 65 7176 24311 Ddc ko00380 Tryptophan metabolism 0.318370652447073 -1.14453900122272 42 1 0.0153846153846154 65 7176 24311 Ddc rno04978 Mineral absorption 0.318370652447073 -1.14453900122272 42 1 0.0153846153846154 65 7176 29292 Ftl1 rno00600 Sphingolipid metabolism 0.330735985451681 -1.10643484891297 44 1 0.0153846153846154 65 7176 29204 Neu2 ko00600 Sphingolipid metabolism 0.330735985451681 -1.10643484891297 44 1 0.0153846153846154 65 7176 29204 Neu2 ko00071 Fatty acid degradation 0.342880390165744 -1.07037360934996 46 1 0.0153846153846154 65 7176 25756 Cpt1b rno00071 Fatty acid degradation 0.342880390165744 -1.07037360934996 46 1 0.0153846153846154 65 7176 25756 Cpt1b rno04310 Wnt signaling pathway 0.346699319378559 -1.0592973894354 135 2 0.0307692307692308 65 7176 24246,303743 Camk2d,Notum ko04310 Wnt signaling pathway 0.346699319378559 -1.0592973894354 135 2 0.0307692307692308 65 7176 24246,303743 Camk2d,Notum rno04072 Phospholipase D signaling pathway 0.353310071917073 -1.04040921690826 137 2 0.0307692307692308 65 7176 60590,24417 Grm8,Grm4 ko04072 Phospholipase D signaling pathway 0.353310071917073 -1.04040921690826 137 2 0.0307692307692308 65 7176 60590,24417 Grm8,Grm4 ko01212 Fatty acid metabolism 0.360691240367024 -1.01973297646034 49 1 0.0153846153846154 65 7176 25756 Cpt1b rno01212 Fatty acid metabolism 0.360691240367024 -1.01973297646034 49 1 0.0153846153846154 65 7176 25756 Cpt1b ko05014 Amyotrophic lateral sclerosis (ALS) 0.378026565956109 -0.972790805524927 52 1 0.0153846153846154 65 7176 24688 Prph rno05014 Amyotrophic lateral sclerosis (ALS) 0.378026565956109 -0.972790805524927 52 1 0.0153846153846154 65 7176 24688 Prph ko00561 Glycerolipid metabolism 0.394898869640742 -0.929125573087293 55 1 0.0153846153846154 65 7176 362261 Lpin3 rno00561 Glycerolipid metabolism 0.394898869640742 -0.929125573087293 55 1 0.0153846153846154 65 7176 362261 Lpin3 rno05223 Non-small cell lung cancer 0.400422191293096 -0.915235810266929 56 1 0.0153846153846154 65 7176 54355 Rassf5 ko05223 Non-small cell lung cancer 0.400422191293096 -0.915235810266929 56 1 0.0153846153846154 65 7176 54355 Rassf5 ko04530 Tight junction 0.418003926847166 -0.872264452130297 157 2 0.0307692307692308 65 7176 24255,58808 Cftr,Mpp4 rno04530 Tight junction 0.418003926847166 -0.872264452130297 157 2 0.0307692307692308 65 7176 58808,24255 Mpp4,Cftr ko05214 Glioma 0.422023374055068 -0.86269457772394 60 1 0.0153846153846154 65 7176 24246 Camk2d rno05214 Glioma 0.422023374055068 -0.86269457772394 60 1 0.0153846153846154 65 7176 24246 Camk2d ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0.427302812041709 -0.850262355399661 61 1 0.0153846153846154 65 7176 300992 Cacna2d2 rno05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 0.427302812041709 -0.850262355399661 61 1 0.0153846153846154 65 7176 300992 Cacna2d2 rno04720 Long-term potentiation 0.432534761045943 -0.838092583479327 62 1 0.0153846153846154 65 7176 24246 Camk2d rno04721 Synaptic vesicle cycle 0.432534761045943 -0.838092583479327 62 1 0.0153846153846154 65 7176 501005 Cplx3 ko04721 Synaptic vesicle cycle 0.432534761045943 -0.838092583479327 62 1 0.0153846153846154 65 7176 501005 Cplx3 ko04720 Long-term potentiation 0.432534761045943 -0.838092583479327 62 1 0.0153846153846154 65 7176 24246 Camk2d rno04062 Chemokine signaling pathway 0.443009669999055 -0.814163680734933 165 2 0.0307692307692308 65 7176 60449,361714 Gnb3,Rasgrp2 ko04062 Chemokine signaling pathway 0.443009669999055 -0.814163680734933 165 2 0.0307692307692308 65 7176 60449,361714 Gnb3,Rasgrp2 rno00562 Inositol phosphate metabolism 0.457996763210122 -0.780893162119733 67 1 0.0153846153846154 65 7176 282636 Impa2 ko00562 Inositol phosphate metabolism 0.457996763210122 -0.780893162119733 67 1 0.0153846153846154 65 7176 282636 Impa2 rno05222 Small cell lung cancer 0.462952482773276 -0.770130859162022 68 1 0.0153846153846154 65 7176 192362 Lamc2 ko05222 Small cell lung cancer 0.462952482773276 -0.770130859162022 68 1 0.0153846153846154 65 7176 192362 Lamc2 rno04976 Bile secretion 0.467863581340539 -0.759578518418888 69 1 0.0153846153846154 65 7176 24255 Cftr ko04976 Bile secretion 0.467863581340539 -0.759578518418888 69 1 0.0153846153846154 65 7176 24255 Cftr rno04920 Adipocytokine signaling pathway 0.47273045444826 -0.749229916670013 70 1 0.0153846153846154 65 7176 25756 Cpt1b ko04920 Adipocytokine signaling pathway 0.47273045444826 -0.749229916670013 70 1 0.0153846153846154 65 7176 25756 Cpt1b ko04917 Prolactin signaling pathway 0.477553494201959 -0.739079095593892 71 1 0.0153846153846154 65 7176 25085 Th rno04917 Prolactin signaling pathway 0.477553494201959 -0.739079095593892 71 1 0.0153846153846154 65 7176 25085 Th ko00590 Arachidonic acid metabolism 0.482333089261296 -0.729120347042466 72 1 0.0153846153846154 65 7176 81639 Alox15 rno00590 Arachidonic acid metabolism 0.482333089261296 -0.729120347042466 72 1 0.0153846153846154 65 7176 81639 Alox15 rno03008 Ribosome biogenesis in eukaryotes 0.487069624907077 -0.719348199163364 73 1 0.0153846153846154 65 7176 100861535 Rn28s ko03008 Ribosome biogenesis in eukaryotes 0.487069624907077 -0.719348199163364 73 1 0.0153846153846154 65 7176 100861535 Rn28s rno04974 Protein digestion and absorption 0.496415042271502 -0.700342923388197 75 1 0.0153846153846154 65 7176 140448 Slc8a3 ko04974 Protein digestion and absorption 0.496415042271502 -0.700342923388197 75 1 0.0153846153846154 65 7176 140448 Slc8a3 ko01230 Biosynthesis of amino acids 0.501024677846068 -0.691099921932588 76 1 0.0153846153846154 65 7176 25698 Ass1 rno01230 Biosynthesis of amino acids 0.501024677846068 -0.691099921932588 76 1 0.0153846153846154 65 7176 25698 Ass1 rno04151 PI3K-Akt signaling pathway 0.503722172402443 -0.685730408135529 295 3 0.0461538461538462 65 7176 116683,192362,60449 Efna5,Lamc2,Gnb3 ko04151 PI3K-Akt signaling pathway 0.503722172402443 -0.685730408135529 295 3 0.0461538461538462 65 7176 116683,192362,60449 Efna5,Lamc2,Gnb3 rno03320 PPAR signaling pathway 0.505592761784386 -0.682023752342975 77 1 0.0153846153846154 65 7176 25756 Cpt1b ko03320 PPAR signaling pathway 0.505592761784386 -0.682023752342975 77 1 0.0153846153846154 65 7176 25756 Cpt1b ko04350 TGF-beta signaling pathway 0.51905137513755 -0.655752412010972 80 1 0.0153846153846154 65 7176 29373 Bmp2 rno04350 TGF-beta signaling pathway 0.51905137513755 -0.655752412010972 80 1 0.0153846153846154 65 7176 29373 Bmp2 rno05416 Viral myocarditis 0.51905137513755 -0.655752412010972 80 1 0.0153846153846154 65 7176 29557 Myh7 rno00564 Glycerophospholipid metabolism 0.52345690792402 -0.647300567391024 81 1 0.0153846153846154 65 7176 362261 Lpin3 rno04911 Insulin secretion 0.52345690792402 -0.647300567391024 81 1 0.0153846153846154 65 7176 24246 Camk2d ko00564 Glycerophospholipid metabolism 0.52345690792402 -0.647300567391024 81 1 0.0153846153846154 65 7176 362261 Lpin3 ko04012 ErbB signaling pathway 0.527822700874384 -0.638994845465753 82 1 0.0153846153846154 65 7176 24246 Camk2d rno04012 ErbB signaling pathway 0.527822700874384 -0.638994845465753 82 1 0.0153846153846154 65 7176 24246 Camk2d ko05205 Proteoglycans in cancer 0.531281890716206 -0.632462530961767 195 2 0.0307692307692308 65 7176 29499,24246 Shh,Camk2d rno05205 Proteoglycans in cancer 0.531281890716206 -0.632462530961767 195 2 0.0307692307692308 65 7176 29499,24246 Shh,Camk2d ko05146 Amoebiasis 0.532149106908592 -0.630831552766544 83 1 0.0153846153846154 65 7176 192362 Lamc2 ko04912 GnRH signaling pathway 0.532149106908592 -0.630831552766544 83 1 0.0153846153846154 65 7176 24246 Camk2d rno05146 Amoebiasis 0.532149106908592 -0.630831552766544 83 1 0.0153846153846154 65 7176 192362 Lamc2 rno04912 GnRH signaling pathway 0.532149106908592 -0.630831552766544 83 1 0.0153846153846154 65 7176 24246 Camk2d rno04070 Phosphatidylinositol signaling system 0.553202471155538 -0.592031212181378 88 1 0.0153846153846154 65 7176 282636 Impa2 ko04070 Phosphatidylinositol signaling system 0.553202471155538 -0.592031212181378 88 1 0.0153846153846154 65 7176 282636 Impa2 ko04060 Cytokine-cytokine receptor interaction 0.555904580442323 -0.587158617369083 204 2 0.0307692307692308 65 7176 29373,362628 Bmp2,Ifnlr1 rno04060 Cytokine-cytokine receptor interaction 0.555904580442323 -0.587158617369083 204 2 0.0307692307692308 65 7176 362628,29373 Ifnlr1,Bmp2 ko05231 Choline metabolism in cancer 0.561360119703362 -0.577392654799986 90 1 0.0153846153846154 65 7176 85426 Slc5a7 rno05231 Choline metabolism in cancer 0.561360119703362 -0.577392654799986 90 1 0.0153846153846154 65 7176 85426 Slc5a7 ko04916 Melanogenesis 0.565383770874664 -0.570250537928978 91 1 0.0153846153846154 65 7176 24246 Camk2d rno04916 Melanogenesis 0.565383770874664 -0.570250537928978 91 1 0.0153846153846154 65 7176 24246 Camk2d rno04972 Pancreatic secretion 0.577237936606772 -0.549500729005272 94 1 0.0153846153846154 65 7176 24255 Cftr ko04972 Pancreatic secretion 0.577237936606772 -0.549500729005272 94 1 0.0153846153846154 65 7176 24255 Cftr rno04066 HIF-1 signaling pathway 0.596291311299315 -0.517025953981681 99 1 0.0153846153846154 65 7176 24246 Camk2d ko05145 Toxoplasmosis 0.610923026084675 -0.492784307968197 103 1 0.0153846153846154 65 7176 192362 Lamc2 rno05145 Toxoplasmosis 0.610923026084675 -0.492784307968197 103 1 0.0153846153846154 65 7176 192362 Lamc2 rno04931 Insulin resistance 0.618041807060507 -0.481199174847312 105 1 0.0153846153846154 65 7176 25756 Cpt1b ko04114 Oocyte meiosis 0.621552948701409 -0.475534176645926 106 1 0.0153846153846154 65 7176 24246 Camk2d rno04114 Oocyte meiosis 0.621552948701409 -0.475534176645926 106 1 0.0153846153846154 65 7176 24246 Camk2d ko04670 Leukocyte transendothelial migration 0.638637524647357 -0.448418239627057 111 1 0.0153846153846154 65 7176 54355 Rassf5 rno04670 Leukocyte transendothelial migration 0.638637524647357 -0.448418239627057 111 1 0.0153846153846154 65 7176 54355 Rassf5 ko04010 MAPK signaling pathway 0.649794594142533 -0.43109897504531 242 2 0.0307692307692308 65 7176 300992,361714 Cacna2d2,Rasgrp2 rno04010 MAPK signaling pathway 0.649794594142533 -0.43109897504531 242 2 0.0307692307692308 65 7176 300992,361714 Cacna2d2,Rasgrp2 rno04722 Neurotrophin signaling pathway 0.654962172092249 -0.423177797545544 116 1 0.0153846153846154 65 7176 24246 Camk2d ko04722 Neurotrophin signaling pathway 0.654962172092249 -0.423177797545544 116 1 0.0153846153846154 65 7176 24246 Camk2d ko04910 Insulin signaling pathway 0.685463432590976 -0.377660125544155 126 1 0.0153846153846154 65 7176 24679 Prkar2b rno04910 Insulin signaling pathway 0.685463432590976 -0.377660125544155 126 1 0.0153846153846154 65 7176 24679 Prkar2b ko03010 Ribosome 0.685463432590976 -0.377660125544155 126 1 0.0153846153846154 65 7176 100861535 Rn28s rno03010 Ribosome 0.685463432590976 -0.377660125544155 126 1 0.0153846153846154 65 7176 100861535 Rn28s rno04550 Signaling pathways regulating pluripotency of stem cells 0.696906323182086 -0.361104277279807 130 1 0.0153846153846154 65 7176 367944 Zic3 ko04550 Signaling pathways regulating pluripotency of stem cells 0.696906323182086 -0.361104277279807 130 1 0.0153846153846154 65 7176 367944 Zic3 ko04630 Jak-STAT signaling pathway 0.702473056692376 -0.353148231972559 132 1 0.0153846153846154 65 7176 362628 Ifnlr1 rno04630 Jak-STAT signaling pathway 0.702473056692376 -0.353148231972559 132 1 0.0153846153846154 65 7176 362628 Ifnlr1 rno05418 Fluid shear stress and atherosclerosis 0.721175333475443 -0.326872990296332 139 1 0.0153846153846154 65 7176 25698 Ass1 ko05418 Fluid shear stress and atherosclerosis 0.721175333475443 -0.326872990296332 139 1 0.0153846153846154 65 7176 25698 Ass1 rno04390 Hippo signaling pathway 0.728831682091671 -0.316312462395533 142 1 0.0153846153846154 65 7176 29373 Bmp2 ko04390 Hippo signaling pathway 0.728831682091671 -0.316312462395533 142 1 0.0153846153846154 65 7176 29373 Bmp2 ko05202 Transcriptional misregulation in cancer 0.73871896189205 -0.30283772550378 146 1 0.0153846153846154 65 7176 311876 Pbx3 rno05202 Transcriptional misregulation in cancer 0.73871896189205 -0.30283772550378 146 1 0.0153846153846154 65 7176 311876 Pbx3 ko05152 Tuberculosis 0.768464166090268 -0.263361345470235 159 1 0.0153846153846154 65 7176 24246 Camk2d rno05152 Tuberculosis 0.768464166090268 -0.263361345470235 159 1 0.0153846153846154 65 7176 24246 Camk2d ko00230 Purine metabolism 0.776926547425234 -0.252409466641325 163 1 0.0153846153846154 65 7176 497757 Gucy1a1 rno00230 Purine metabolism 0.776926547425234 -0.252409466641325 163 1 0.0153846153846154 65 7176 497757 Gucy1a1 ko04510 Focal adhesion 0.794869256694338 -0.229577634840592 172 1 0.0153846153846154 65 7176 192362 Lamc2 rno04510 Focal adhesion 0.794869256694338 -0.229577634840592 172 1 0.0153846153846154 65 7176 192362 Lamc2 rno04144 Endocytosis 0.915911831375915 -0.087835172897141 267 1 0.0153846153846154 65 7176 24925 Adrb1 ko04144 Endocytosis 0.915911831375915 -0.087835172897141 267 1 0.0153846153846154 65 7176 24925 Adrb1 rno01100 Metabolic pathways 0.934867490488135 -0.0673504811399413 1200 7 0.107692307692308 65 7176 24311,25085,114113,25698,362261,81639,282636 Ddc,Th,Pafah1b3,Ass1,Lpin3,Alox15,Impa2 rno04740 Olfactory transduction 0.998208882773662 -0.00179272319473556 1085 3 0.0461538461538462 65 7176 24246,140448,25523 Camk2d,Slc8a3,Prkg2 ko04740 Olfactory transduction 0.998208882773662 -0.00179272319473556 1085 3 0.0461538461538462 65 7176 25523,140448,24246 Prkg2,Slc8a3,Camk2d rno_M00396 Lsm 2-8 complex 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00397 Lsm 1-7 complex 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00120 Coenzyme A biosynthesis, pantothenate => CoA 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00120 Coenzyme A biosynthesis, pantothenate => CoA 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00065 GPI-anchor biosynthesis, core oligosaccharide 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00396 Lsm 2-8 complex 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00072 N-glycosylation by oligosaccharyltransferase 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00397 Lsm 1-7 complex 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00065 GPI-anchor biosynthesis, core oligosaccharide 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00072 N-glycosylation by oligosaccharyltransferase 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00687 MAPK (ERK1/2) signaling 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno_M00687 MAPK (ERK1/2) signaling 0.999999999990697 -9.3032094340294e-12 7 0 0 65 7176 rno00740 Riboflavin metabolism 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno04122 Sulfur relay system 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00409 ESCRT-I complex 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00391 Exosome, eukaryotes 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 ko04122 Sulfur relay system 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno_M00391 Exosome, eukaryotes 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno_M00086 beta-Oxidation, acyl-CoA synthesis 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00406 TREX complex 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno_M00680 TGF-beta signaling 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00086 beta-Oxidation, acyl-CoA synthesis 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 ko00740 Riboflavin metabolism 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00680 TGF-beta signaling 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno_M00409 ESCRT-I complex 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00693 Cell cycle - G2/M transition 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno_M00693 Cell cycle - G2/M transition 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 rno_M00406 TREX complex 0.999999999992715 -7.28528407588099e-12 8 0 0 65 7176 M00098 Acylglycerol degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00004 Pentose phosphate pathway (Pentose phosphate cycle) 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00681 Activin signaling 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00412 ESCRT-III complex 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00077 Chondroitin sulfate degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00035 Methionine degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00412 ESCRT-III complex 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00296 BER complex 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00095 C5 isoprenoid biosynthesis, mevalonate pathway 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno00430 Taurine and hypotaurine metabolism 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00004 Pentose phosphate pathway (Pentose phosphate cycle) 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00076 Dermatan sulfate degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00076 Dermatan sulfate degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno00072 Synthesis and degradation of ketone bodies 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00296 BER complex 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00098 Acylglycerol degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 ko00430 Taurine and hypotaurine metabolism 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00035 Methionine degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00404 COPII complex 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00404 COPII complex 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 rno_M00681 Activin signaling 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 ko00072 Synthesis and degradation of ketone bodies 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00077 Chondroitin sulfate degradation 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP 0.999999999994873 -5.1274697521513e-12 10 0 0 65 7176 ko04659 Th17 cell differentiation 0.999999999995171 -4.82951258993828e-12 99 0 0 65 7176 rno04659 Th17 cell differentiation 0.999999999995171 -4.82951258993828e-12 99 0 0 65 7176 ko00020 Citrate cycle (TCA cycle) 0.999999999995792 -4.20823574423772e-12 31 0 0 65 7176 ko04136 Autophagy - other 0.999999999995792 -4.20823574423772e-12 31 0 0 65 7176 ko04215 Apoptosis - multiple species 0.999999999995792 -4.20823574423772e-12 31 0 0 65 7176 rno04136 Autophagy - other 0.999999999995792 -4.20823574423772e-12 31 0 0 65 7176 rno04215 Apoptosis - multiple species 0.999999999995792 -4.20823574423772e-12 31 0 0 65 7176 rno00020 Citrate cycle (TCA cycle) 0.999999999995792 -4.20823574423772e-12 31 0 0 65 7176 rno_M00426 Survival motor neuron (SMN) complex 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00351 Spliceosome, U1-snRNP 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00152 Cytochrome bc1 complex 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00290 Holo-TFIIH complex 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00152 Cytochrome bc1 complex 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00361 Nucleotide sugar biosynthesis, eukaryotes 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00426 Survival motor neuron (SMN) complex 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00361 Nucleotide sugar biosynthesis, eukaryotes 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 ko00750 Vitamin B6 metabolism 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00351 Spliceosome, U1-snRNP 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 M00290 Holo-TFIIH complex 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno00750 Vitamin B6 metabolism 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 rno_M00135 GABA biosynthesis, eukaryotes, putrescine => GABA 0.999999999997079 -2.92063214349383e-12 9 0 0 65 7176 ko04975 Fat digestion and absorption 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 ko04672 Intestinal immune network for IgA production 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 rno04672 Intestinal immune network for IgA production 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 rno03420 Nucleotide excision repair 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 ko03022 Basal transcription factors 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 ko03420 Nucleotide excision repair 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 rno04975 Fat digestion and absorption 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 rno03022 Basal transcription factors 0.99999999999819 -1.8096219982305e-12 39 0 0 65 7176 ko05134 Legionellosis 0.999999999998193 -1.80656301709813e-12 51 0 0 65 7176 rno05134 Legionellosis 0.999999999998193 -1.80656301709813e-12 51 0 0 65 7176 ko00100 Steroid biosynthesis 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 rno00100 Steroid biosynthesis 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 M00341 Proteasome, 19S regulatory particle (PA700) 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 ko00514 Other types of O-glycan biosynthesis 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 M00003 Gluconeogenesis, oxaloacetate => fructose-6P 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 rno00514 Other types of O-glycan biosynthesis 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 rno_M00352 Spliceosome, U2-snRNP 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 rno_M00003 Gluconeogenesis, oxaloacetate => fructose-6P 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 rno_M00154 Cytochrome c oxidase 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 M00154 Cytochrome c oxidase 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 M00352 Spliceosome, U2-snRNP 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 rno_M00341 Proteasome, 19S regulatory particle (PA700) 0.999999999998202 -1.79767883254946e-12 19 0 0 65 7176 ko00620 Pyruvate metabolism 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 ko04960 Aldosterone-regulated sodium reabsorption 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 rno00860 Porphyrin and chlorophyll metabolism 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 ko00260 Glycine, serine and threonine metabolism 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 rno00260 Glycine, serine and threonine metabolism 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 rno04960 Aldosterone-regulated sodium reabsorption 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 ko00860 Porphyrin and chlorophyll metabolism 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 rno00620 Pyruvate metabolism 0.999999999998393 -1.60702599258395e-12 38 0 0 65 7176 rno_M00160 V-type ATPase, eukaryotes 0.999999999998678 -1.32240729322862e-12 24 0 0 65 7176 M00160 V-type ATPase, eukaryotes 0.999999999998678 -1.32240729322862e-12 24 0 0 65 7176 rno04977 Vitamin digestion and absorption 0.999999999998678 -1.32240729322862e-12 24 0 0 65 7176 ko04977 Vitamin digestion and absorption 0.999999999998678 -1.32240729322862e-12 24 0 0 65 7176 ko04392 Hippo signaling pathway -multiple species 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 ko00515 Mannose type O-glycan biosynthesis 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 rno_M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 rno_M00009 Citrate cycle (TCA cycle, Krebs cycle) 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 rno00515 Mannose type O-glycan biosynthesis 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 M00009 Citrate cycle (TCA cycle, Krebs cycle) 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 rno04392 Hippo signaling pathway -multiple species 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate 0.999999999999357 -6.43129712382403e-13 23 0 0 65 7176 ko00061 Fatty acid biosynthesis 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 M00389 APC/C complex 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno00730 Thiamine metabolism 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 M00295 BRCA1-associated genome surveillance complex (BASC) 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno_M00389 APC/C complex 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno00604 Glycosphingolipid biosynthesis - ganglio series 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 M00695 cAMP signaling 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno_M00295 BRCA1-associated genome surveillance complex (BASC) 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno_M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno_M00695 cAMP signaling 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 ko00604 Glycosphingolipid biosynthesis - ganglio series 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno00061 Fatty acid biosynthesis 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 ko00730 Thiamine metabolism 0.999999999999641 -3.5877960799569e-13 14 0 0 65 7176 rno03040 Spliceosome 1.00000000000057 5.71999980576181e-13 120 0 0 65 7176 ko03040 Spliceosome 1.00000000000057 5.71999980576181e-13 120 0 0 65 7176 rno00983 Drug metabolism - other enzymes 1.0000000000008 7.98504080520722e-13 52 0 0 65 7176 rno05221 Acute myeloid leukemia 1.0000000000008 7.98504080520722e-13 52 0 0 65 7176 ko00983 Drug metabolism - other enzymes 1.0000000000008 7.98504080520722e-13 52 0 0 65 7176 ko05221 Acute myeloid leukemia 1.0000000000008 7.98504080520722e-13 52 0 0 65 7176 ko00190 Oxidative phosphorylation 1.00000000000088 8.77428865807543e-13 114 0 0 65 7176 rno00190 Oxidative phosphorylation 1.00000000000088 8.77428865807543e-13 114 0 0 65 7176 ko04614 Renin-angiotensin system 1.00000000000168 1.68394963589901e-12 30 0 0 65 7176 ko00640 Propanoate metabolism 1.00000000000168 1.68394963589901e-12 30 0 0 65 7176 rno00640 Propanoate metabolism 1.00000000000168 1.68394963589901e-12 30 0 0 65 7176 rno04614 Renin-angiotensin system 1.00000000000168 1.68394963589901e-12 30 0 0 65 7176 rno05144 Malaria 1.00000000000222 2.21732635119561e-12 53 0 0 65 7176 ko05144 Malaria 1.00000000000222 2.21732635119561e-12 53 0 0 65 7176 ko00270 Cysteine and methionine metabolism 1.00000000000223 2.23267134781946e-12 43 0 0 65 7176 rno04330 Notch signaling pathway 1.00000000000223 2.23267134781946e-12 43 0 0 65 7176 rno00270 Cysteine and methionine metabolism 1.00000000000223 2.23267134781946e-12 43 0 0 65 7176 ko04330 Notch signaling pathway 1.00000000000223 2.23267134781946e-12 43 0 0 65 7176 rno04668 TNF signaling pathway 1.00000000000239 2.3882851852541e-12 101 0 0 65 7176 ko04668 TNF signaling pathway 1.00000000000239 2.3882851852541e-12 101 0 0 65 7176 ko00760 Nicotinate and nicotinamide metabolism 1.00000000000239 2.39428106446589e-12 29 0 0 65 7176 rno00760 Nicotinate and nicotinamide metabolism 1.00000000000239 2.39428106446589e-12 29 0 0 65 7176 rno00052 Galactose metabolism 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 rno00030 Pentose phosphate pathway 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 rno01523 Antifolate resistance 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 rno00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 ko00052 Galactose metabolism 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 ko00030 Pentose phosphate pathway 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 ko01523 Antifolate resistance 1.00000000000245 2.45476278997415e-12 28 0 0 65 7176 rno04918 Thyroid hormone synthesis 1.00000000000264 2.6449721661072e-12 69 0 0 65 7176 rno04940 Type I diabetes mellitus 1.00000000000264 2.6449721661072e-12 69 0 0 65 7176 rno03018 RNA degradation 1.00000000000264 2.6449721661072e-12 69 0 0 65 7176 ko04940 Type I diabetes mellitus 1.00000000000264 2.6449721661072e-12 69 0 0 65 7176 ko04918 Thyroid hormone synthesis 1.00000000000264 2.6449721661072e-12 69 0 0 65 7176 ko03018 RNA degradation 1.00000000000264 2.6449721661072e-12 69 0 0 65 7176 M00403 HRD1/SEL1 ERAD complex 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 M00692 Cell cycle - G1/S transition 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 rno_M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 rno_M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 ko03450 Non-homologous end-joining 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 rno_M00692 Cell cycle - G1/S transition 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 rno_M00403 HRD1/SEL1 ERAD complex 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 rno03450 Non-homologous end-joining 1.00000000000286 2.85585547367848e-12 12 0 0 65 7176 rno00592 alpha-Linolenic acid metabolism 1.00000000000296 2.96492933988051e-12 20 0 0 65 7176 rno_M00688 MAPK (JNK) signaling 1.00000000000296 2.96492933988051e-12 20 0 0 65 7176 M00688 MAPK (JNK) signaling 1.00000000000296 2.96492933988051e-12 20 0 0 65 7176 ko00592 alpha-Linolenic acid metabolism 1.00000000000296 2.96492933988051e-12 20 0 0 65 7176 rno03410 Base excision repair 1.00000000000311 3.10949489663999e-12 33 0 0 65 7176 rno03030 DNA replication 1.00000000000311 3.10949489663999e-12 33 0 0 65 7176 M00355 Spliceosome, 35S U5-snRNP 1.00000000000311 3.10949489663999e-12 33 0 0 65 7176 rno_M00355 Spliceosome, 35S U5-snRNP 1.00000000000311 3.10949489663999e-12 33 0 0 65 7176 ko03410 Base excision repair 1.00000000000311 3.10949489663999e-12 33 0 0 65 7176 ko03030 DNA replication 1.00000000000311 3.10949489663999e-12 33 0 0 65 7176 ko05010 Alzheimer's disease 1.00000000000316 3.16291610633062e-12 159 0 0 65 7176 ko04514 Cell adhesion molecules (CAMs) 1.00000000000316 3.16291610633062e-12 159 0 0 65 7176 rno04514 Cell adhesion molecules (CAMs) 1.00000000000316 3.16291610633062e-12 159 0 0 65 7176 rno05010 Alzheimer's disease 1.00000000000316 3.16291610633062e-12 159 0 0 65 7176 rno04115 p53 signaling pathway 1.00000000000332 3.31585590870727e-12 65 0 0 65 7176 ko04115 p53 signaling pathway 1.00000000000332 3.31585590870727e-12 65 0 0 65 7176 M00294 DNA polymerase gamma complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 ko00780 Biotin metabolism 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00293 DNA polymerase zeta complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00151 Cytochrome bc1 complex respiratory unit 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 ko00300 Lysine biosynthesis 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00083 Fatty acid biosynthesis, elongation 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00083 Fatty acid biosynthesis, elongation 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00297 DNA-PK complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00392 Ski complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00338 Cysteine biosynthesis, homocysteine + serine => cysteine 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno00780 Biotin metabolism 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00392 Ski complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00293 DNA polymerase zeta complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00066 Lactosylceramide biosynthesis 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00103 Cholecalciferol biosynthesis 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00399 Cap binding complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00399 Cap binding complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00066 Lactosylceramide biosynthesis 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00297 DNA-PK complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno00300 Lysine biosynthesis 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno_M00294 DNA polymerase gamma complex 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00151 Cytochrome bc1 complex respiratory unit 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 M00103 Cholecalciferol biosynthesis 1.0000000000036 3.602278143746e-12 2 0 0 65 7176 rno00040 Pentose and glucuronate interconversions 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 ko04130 SNARE interactions in vesicular transport 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 rno05340 Primary immunodeficiency 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 ko05340 Primary immunodeficiency 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 rno05020 Prion diseases 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 rno04130 SNARE interactions in vesicular transport 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 ko05020 Prion diseases 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 ko00040 Pentose and glucuronate interconversions 1.00000000000372 3.72107574924876e-12 32 0 0 65 7176 ko04662 B cell receptor signaling pathway 1.00000000000372 3.72352264325644e-12 66 0 0 65 7176 ko05140 Leishmaniasis 1.00000000000372 3.72352264325644e-12 66 0 0 65 7176 rno04662 B cell receptor signaling pathway 1.00000000000372 3.72352264325644e-12 66 0 0 65 7176 rno05140 Leishmaniasis 1.00000000000372 3.72352264325644e-12 66 0 0 65 7176 ko00010 Glycolysis / Gluconeogenesis 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 rno05330 Allograft rejection 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 rno00982 Drug metabolism - cytochrome P450 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 ko00982 Drug metabolism - cytochrome P450 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 ko00980 Metabolism of xenobiotics by cytochrome P450 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 rno00010 Glycolysis / Gluconeogenesis 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 ko05330 Allograft rejection 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 ko04664 Fc epsilon RI signaling pathway 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 rno00980 Metabolism of xenobiotics by cytochrome P450 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 rno04664 Fc epsilon RI signaling pathway 1.00000000000402 4.02362063741081e-12 62 0 0 65 7176 M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00027 GABA (gamma-Aminobutyrate) shunt 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno00290 Valine, leucine and isoleucine biosynthesis 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00402 Translocon-associated protein (TRAP) complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00005 PRPP biosynthesis, ribose 5P => PRPP 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00685 Apoptotic machinery 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno00524 Neomycin, kanamycin and gentamicin biosynthesis 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00262 DNA polymerase delta complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00005 PRPP biosynthesis, ribose 5P => PRPP 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00690 MAPK (ERK5) signaling 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00401 Sec61 complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00148 Succinate dehydrogenase (ubiquinone) 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00401 Sec61 complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00263 DNA polymerase epsilon complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00384 Cul3-SPOP complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00384 Cul3-SPOP complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 ko00290 Valine, leucine and isoleucine biosynthesis 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00015 Proline biosynthesis, glutamate => proline 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00148 Succinate dehydrogenase (ubiquinone) 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00261 DNA polymerase alpha / primase complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00015 Proline biosynthesis, glutamate => proline 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00263 DNA polymerase epsilon complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00262 DNA polymerase delta complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00402 Translocon-associated protein (TRAP) complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00395 Decapping complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00381 SCF-SKP2 complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00286 GINS complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00393 TRAMP complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 ko00524 Neomycin, kanamycin and gentamicin biosynthesis 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00690 MAPK (ERK5) signaling 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00381 SCF-SKP2 complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00027 GABA (gamma-Aminobutyrate) shunt 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00685 Apoptotic machinery 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00261 DNA polymerase alpha / primase complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00393 TRAMP complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00286 GINS complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00395 Decapping complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno_M00425 H/ACA ribonucleoprotein complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 M00425 H/ACA ribonucleoprotein complex 1.00000000000424 4.2371210251187e-12 4 0 0 65 7176 rno00670 One carbon pool by folate 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 ko00770 Pantothenate and CoA biosynthesis 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 ko00910 Nitrogen metabolism 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 rno00531 Glycosaminoglycan degradation 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 rno00910 Nitrogen metabolism 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 ko00531 Glycosaminoglycan degradation 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 M00430 Exon junction complex (EJC) 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 ko00670 One carbon pool by folate 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 rno00770 Pantothenate and CoA biosynthesis 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 rno_M00430 Exon junction complex (EJC) 1.00000000000432 4.31584478528526e-12 17 0 0 65 7176 ko05162 Measles 1.00000000000452 4.51527391397969e-12 119 0 0 65 7176 rno05162 Measles 1.00000000000452 4.51527391397969e-12 119 0 0 65 7176 ko03015 mRNA surveillance pathway 1.00000000000461 4.61341886131173e-12 80 0 0 65 7176 rno03015 mRNA surveillance pathway 1.00000000000461 4.61341886131173e-12 80 0 0 65 7176 rno04973 Carbohydrate digestion and absorption 1.0000000000047 4.69793684117242e-12 37 0 0 65 7176 ko04973 Carbohydrate digestion and absorption 1.0000000000047 4.69793684117242e-12 37 0 0 65 7176 rno05219 Bladder cancer 1.0000000000047 4.69793684117242e-12 37 0 0 65 7176 ko05219 Bladder cancer 1.0000000000047 4.69793684117242e-12 37 0 0 65 7176 ko00480 Glutathione metabolism 1.00000000000478 4.7806387769306e-12 54 0 0 65 7176 rno00480 Glutathione metabolism 1.00000000000478 4.7806387769306e-12 54 0 0 65 7176 rno04370 VEGF signaling pathway 1.00000000000478 4.7806387769306e-12 54 0 0 65 7176 ko04370 VEGF signaling pathway 1.00000000000478 4.7806387769306e-12 54 0 0 65 7176 M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00094 Ceramide biosynthesis 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00034 Methionine salvage pathway 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00388 ECS complex 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno00130 Ubiquinone and other terpenoid-quinone biosynthesis 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00182 RNA polymerase I, eukaryotes 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 ko00920 Sulfur metabolism 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno00920 Sulfur metabolism 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00180 RNA polymerase II, eukaryotes 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00182 RNA polymerase I, eukaryotes 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00388 ECS complex 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00180 RNA polymerase II, eukaryotes 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00034 Methionine salvage pathway 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno_M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 M00094 Ceramide biosynthesis 1.00000000000486 4.85952337760671e-12 11 0 0 65 7176 rno05150 Staphylococcus aureus infection 1.00000000000495 4.94759761402862e-12 46 0 0 65 7176 ko03050 Proteasome 1.00000000000495 4.94759761402862e-12 46 0 0 65 7176 ko05150 Staphylococcus aureus infection 1.00000000000495 4.94759761402862e-12 46 0 0 65 7176 ko00520 Amino sugar and nucleotide sugar metabolism 1.00000000000495 4.94759761402862e-12 46 0 0 65 7176 rno00520 Amino sugar and nucleotide sugar metabolism 1.00000000000495 4.94759761402862e-12 46 0 0 65 7176 rno03050 Proteasome 1.00000000000495 4.94759761402862e-12 46 0 0 65 7176 ko01040 Biosynthesis of unsaturated fatty acids 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 ko05310 Asthma 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 rno05310 Asthma 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 ko00512 Mucin type O-glycan biosynthesis 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 M00014 Glucuronate pathway (uronate pathway) 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 rno01040 Biosynthesis of unsaturated fatty acids 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 rno00512 Mucin type O-glycan biosynthesis 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 rno_M00014 Glucuronate pathway (uronate pathway) 1.00000000000519 5.19183931679533e-12 25 0 0 65 7176 ko00051 Fructose and mannose metabolism 1.00000000000613 6.12509764100175e-12 35 0 0 65 7176 rno00051 Fructose and mannose metabolism 1.00000000000613 6.12509764100175e-12 35 0 0 65 7176 rno00280 Valine, leucine and isoleucine degradation 1.00000000000619 6.19348365017138e-12 49 0 0 65 7176 ko00280 Valine, leucine and isoleucine degradation 1.00000000000619 6.19348365017138e-12 49 0 0 65 7176 ko03060 Protein export 1.00000000000652 6.52057409812931e-12 22 0 0 65 7176 rno03060 Protein export 1.00000000000652 6.52057409812931e-12 22 0 0 65 7176 ko04964 Proximal tubule bicarbonate reclamation 1.00000000000652 6.52057409812931e-12 22 0 0 65 7176 rno04320 Dorso-ventral axis formation 1.00000000000652 6.52057409812931e-12 22 0 0 65 7176 rno04964 Proximal tubule bicarbonate reclamation 1.00000000000652 6.52057409812931e-12 22 0 0 65 7176 ko04320 Dorso-ventral axis formation 1.00000000000652 6.52057409812931e-12 22 0 0 65 7176 rno_M00684 JAK-STAT signaling 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 M00684 JAK-STAT signaling 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 rno01210 2-Oxocarboxylic acid metabolism 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 ko01210 2-Oxocarboxylic acid metabolism 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 M00337 Immunoproteasome 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 rno_M00337 Immunoproteasome 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 rno00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 rno_M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP 1.000000000007 7.00054215522533e-12 18 0 0 65 7176 rno05161 Hepatitis B 1.00000000000712 7.12220227642103e-12 127 0 0 65 7176 rno05133 Pertussis 1.00000000000728 7.28459540536583e-12 68 0 0 65 7176 ko05133 Pertussis 1.00000000000728 7.28459540536583e-12 68 0 0 65 7176 ko05220 Chronic myeloid leukemia 1.00000000000728 7.28459540536583e-12 68 0 0 65 7176 rno05220 Chronic myeloid leukemia 1.00000000000728 7.28459540536583e-12 68 0 0 65 7176 rno04140 Autophagy - animal 1.00000000000735 7.3478782495499e-12 125 0 0 65 7176 ko04140 Autophagy - animal 1.00000000000735 7.3478782495499e-12 125 0 0 65 7176 ko05321 Inflammatory bowel disease (IBD) 1.00000000000736 7.35720388385661e-12 56 0 0 65 7176 rno05321 Inflammatory bowel disease (IBD) 1.00000000000736 7.35720388385661e-12 56 0 0 65 7176 rno00970 Aminoacyl-tRNA biosynthesis 1.00000000000741 7.40782653290507e-12 41 0 0 65 7176 ko00970 Aminoacyl-tRNA biosynthesis 1.00000000000741 7.40782653290507e-12 41 0 0 65 7176 rno04962 Vasopressin-regulated water reabsorption 1.00000000000741 7.40782653290507e-12 41 0 0 65 7176 ko04962 Vasopressin-regulated water reabsorption 1.00000000000741 7.40782653290507e-12 41 0 0 65 7176 rno04930 Type II diabetes mellitus 1.00000000000768 7.6759960888944e-12 45 0 0 65 7176 ko04930 Type II diabetes mellitus 1.00000000000768 7.6759960888944e-12 45 0 0 65 7176 M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 ko00471 D-Glutamine and D-glutamate metabolism 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00288 RPA complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00118 Glutathione biosynthesis, glutamate => glutathione 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00020 Serine biosynthesis, glycerate-3P => serine 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 ko00785 Lipoic acid metabolism 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00390 Exosome, archaea 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00387 SCF-FBW7 complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00100 Sphingosine degradation 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00410 ESCRT-II complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00291 MRN complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00082 Fatty acid biosynthesis, initiation 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00291 MRN complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00100 Sphingosine degradation 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno00785 Lipoic acid metabolism 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00400 p97-Ufd1-Npl4 complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00390 Exosome, archaea 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00408 ESCRT-0 complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00288 RPA complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00400 p97-Ufd1-Npl4 complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00020 Serine biosynthesis, glycerate-3P => serine 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno00471 D-Glutamine and D-glutamate metabolism 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00387 SCF-FBW7 complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00118 Glutathione biosynthesis, glutamate => glutathione 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00134 Polyamine biosynthesis, arginine => ornithine => putrescine 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 M00082 Fatty acid biosynthesis, initiation 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00408 ESCRT-0 complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno_M00410 ESCRT-II complex 1.00000000000775 7.75358663433295e-12 3 0 0 65 7176 rno04919 Thyroid hormone signaling pathway 1.00000000000776 7.76401143101815e-12 110 0 0 65 7176 rno03440 Homologous recombination 1.00000000000796 7.95528892340229e-12 34 0 0 65 7176 ko05143 African trypanosomiasis 1.00000000000796 7.95528892340229e-12 34 0 0 65 7176 rno05143 African trypanosomiasis 1.00000000000796 7.95528892340229e-12 34 0 0 65 7176 rno03460 Fanconi anemia pathway 1.00000000000796 7.95528892340229e-12 34 0 0 65 7176 ko03460 Fanconi anemia pathway 1.00000000000796 7.95528892340229e-12 34 0 0 65 7176 ko03440 Homologous recombination 1.00000000000796 7.95528892340229e-12 34 0 0 65 7176 M00177 Ribosome, eukaryotes 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 rno_M00177 Ribosome, eukaryotes 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 ko04657 IL-17 signaling pathway 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 rno04211 Longevity regulating pathway 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 ko05204 Chemical carcinogenesis 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 rno05204 Chemical carcinogenesis 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 rno04657 IL-17 signaling pathway 1.00000000000796 7.96011044454073e-12 84 0 0 65 7176 ko05016 Huntington's disease 1.00000000000802 8.01539794544541e-12 161 0 0 65 7176 rno05016 Huntington's disease 1.00000000000802 8.01539794544541e-12 161 0 0 65 7176 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1.00000000000891 8.91044256796837e-12 140 0 0 65 7176 rno04932 Non-alcoholic fatty liver disease (NAFLD) 1.00000000000891 8.91044256796837e-12 140 0 0 65 7176 M00056 O-glycan biosynthesis, mucin type core 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 rno00900 Terpenoid backbone biosynthesis 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 ko00900 Terpenoid backbone biosynthesis 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 ko03430 Mismatch repair 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 ko00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 rno03430 Mismatch repair 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 rno00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 rno_M00689 MAPK (p38) signaling 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 rno_M00056 O-glycan biosynthesis, mucin type core 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 M00689 MAPK (p38) signaling 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 rno_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 1.00000000000897 8.97446532438903e-12 21 0 0 65 7176 ko05213 Endometrial cancer 1.00000000000913 9.12605230331978e-12 47 0 0 65 7176 ko04623 Cytosolic DNA-sensing pathway 1.00000000000913 9.12605230331978e-12 47 0 0 65 7176 rno00330 Arginine and proline metabolism 1.00000000000913 9.12605230331978e-12 47 0 0 65 7176 rno04623 Cytosolic DNA-sensing pathway 1.00000000000913 9.12605230331978e-12 47 0 0 65 7176 ko00330 Arginine and proline metabolism 1.00000000000913 9.12605230331978e-12 47 0 0 65 7176 rno05213 Endometrial cancer 1.00000000000913 9.12605230331978e-12 47 0 0 65 7176 M00676 PI3K-Akt signaling 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno00790 Folate biosynthesis 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00353 Spliceosome, Prp19/CDC5L complex 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 M00353 Spliceosome, Prp19/CDC5L complex 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 M00087 beta-Oxidation 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00055 N-glycan precursor biosynthesis 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00683 Hippo signaling 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 M00002 Glycolysis, core module involving three-carbon compounds 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 M00683 Hippo signaling 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00002 Glycolysis, core module involving three-carbon compounds 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00676 PI3K-Akt signaling 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno00533 Glycosaminoglycan biosynthesis - keratan sulfate 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 ko00790 Folate biosynthesis 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno_M00087 beta-Oxidation 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 M00055 N-glycan precursor biosynthesis 1.00000000000914 9.13742021050377e-12 13 0 0 65 7176 rno04810 Regulation of actin cytoskeleton 1.00000000000938 9.3822836217103e-12 196 0 0 65 7176 ko04810 Regulation of actin cytoskeleton 1.00000000000938 9.3822836217103e-12 196 0 0 65 7176 rno04666 Fc gamma R-mediated phagocytosis 1.00000000000941 9.41442040599693e-12 82 0 0 65 7176 rno05215 Prostate cancer 1.00000000000941 9.41442040599693e-12 82 0 0 65 7176 ko05215 Prostate cancer 1.00000000000941 9.41442040599693e-12 82 0 0 65 7176 ko04640 Hematopoietic cell lineage 1.00000000000941 9.41442040599693e-12 82 0 0 65 7176 ko04666 Fc gamma R-mediated phagocytosis 1.00000000000941 9.41442040599693e-12 82 0 0 65 7176 rno04640 Hematopoietic cell lineage 1.00000000000941 9.41442040599693e-12 82 0 0 65 7176 rno05164 Influenza A 1.0000000000096 9.60143742520191e-12 151 0 0 65 7176 ko05164 Influenza A 1.0000000000096 9.60143742520191e-12 151 0 0 65 7176 rno00450 Selenocompound metabolism 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 ko00450 Selenocompound metabolism 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 M00340 Proteasome, 20S core particle 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 rno00120 Primary bile acid biosynthesis 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 ko00120 Primary bile acid biosynthesis 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 rno_M00682 Notch signaling 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 M00682 Notch signaling 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 rno_M00340 Proteasome, 20S core particle 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 M00075 N-glycan biosynthesis, complex type 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 rno_M00075 N-glycan biosynthesis, complex type 1.00000000000974 9.74247025806964e-12 16 0 0 65 7176 ko00410 beta-Alanine metabolism 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 rno00410 beta-Alanine metabolism 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 rno04710 Circadian rhythm 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 rno00500 Starch and sucrose metabolism 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 ko00500 Starch and sucrose metabolism 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 rno04966 Collecting duct acid secretion 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 ko04710 Circadian rhythm 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 ko04966 Collecting duct acid secretion 1.00000000001068 1.06840432680221e-11 27 0 0 65 7176 rno04660 T cell receptor signaling pathway 1.00000000001079 1.07927899418346e-11 100 0 0 65 7176 rno05142 Chagas disease (American trypanosomiasis) 1.00000000001079 1.07927899418346e-11 100 0 0 65 7176 ko05142 Chagas disease (American trypanosomiasis) 1.00000000001079 1.07927899418346e-11 100 0 0 65 7176 ko04660 T cell receptor signaling pathway 1.00000000001079 1.07927899418346e-11 100 0 0 65 7176 rno00310 Lysine degradation 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 rno00510 N-Glycan biosynthesis 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 rno04913 Ovarian steroidogenesis 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 ko00310 Lysine degradation 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 rno04961 Endocrine and other factor-regulated calcium reabsorption 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 ko00510 N-Glycan biosynthesis 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 ko04913 Ovarian steroidogenesis 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 ko04961 Endocrine and other factor-regulated calcium reabsorption 1.00000000001095 1.09461044284613e-11 48 0 0 65 7176 ko04120 Ubiquitin mediated proteolysis 1.00000000001095 1.09469302342386e-11 121 0 0 65 7176 rno04120 Ubiquitin mediated proteolysis 1.00000000001095 1.09469302342386e-11 121 0 0 65 7176 rno04145 Phagosome 1.00000000001097 1.09673248074976e-11 172 0 0 65 7176 ko04145 Phagosome 1.00000000001097 1.09673248074976e-11 172 0 0 65 7176 ko01200 Carbon metabolism 1.00000000001153 1.15312913389762e-11 112 0 0 65 7176 rno01200 Carbon metabolism 1.00000000001153 1.15312913389762e-11 112 0 0 65 7176 rno05320 Autoimmune thyroid disease 1.00000000001157 1.15727190873447e-11 67 0 0 65 7176 rno05218 Melanoma 1.00000000001157 1.15727190873447e-11 67 0 0 65 7176 ko05320 Autoimmune thyroid disease 1.00000000001157 1.15727190873447e-11 67 0 0 65 7176 ko05218 Melanoma 1.00000000001157 1.15727190873447e-11 67 0 0 65 7176 rno04068 FoxO signaling pathway 1.00000000001169 1.16930771810726e-11 123 0 0 65 7176 rno05203 Viral carcinogenesis 1.00000000001213 1.21268333989307e-11 197 0 0 65 7176 ko05203 Viral carcinogenesis 1.00000000001213 1.21268333989307e-11 197 0 0 65 7176 rno05160 Hepatitis C 1.00000000001225 1.22476286163288e-11 117 0 0 65 7176 ko05160 Hepatitis C 1.00000000001225 1.22476286163288e-11 117 0 0 65 7176 rno05169 Epstein-Barr virus infection 1.00000000001266 1.26562269547146e-11 209 0 0 65 7176 ko05169 Epstein-Barr virus infection 1.00000000001266 1.26562269547146e-11 209 0 0 65 7176 ko04110 Cell cycle 1.00000000001284 1.28388840734072e-11 115 0 0 65 7176 rno04110 Cell cycle 1.00000000001284 1.28388840734072e-11 115 0 0 65 7176 M00085 Fatty acid biosynthesis, elongation, mitochondria 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 ko00440 Phosphonate and phosphinate metabolism 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00691 DNA damage-induced cell cycle checkpoints 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00424 Shelterin complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00073 N-glycan precursor trimming 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00691 DNA damage-induced cell cycle checkpoints 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00413 FA core complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00413 FA core complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00047 Creatine pathway 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00428 eIF4F complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00398 Sm core complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00085 Fatty acid biosynthesis, elongation, mitochondria 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00428 eIF4F complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00047 Creatine pathway 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 ko00232 Caffeine metabolism 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00284 Origin recognition complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00398 Sm core complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00285 MCM complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00073 N-glycan precursor trimming 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00284 Origin recognition complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00285 MCM complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00141 C1-unit interconversion, eukaryotes 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno00440 Phosphonate and phosphinate metabolism 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00424 Shelterin complex 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno00232 Caffeine metabolism 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 M00141 C1-unit interconversion, eukaryotes 1.00000000001321 1.32122057973281e-11 6 0 0 65 7176 rno_M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 rno_M00414 Bloom's syndrome complex 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 rno00472 D-Arginine and D-ornithine metabolism 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 M00414 Bloom's syndrome complex 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 ko00472 D-Arginine and D-ornithine metabolism 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 rno_M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine 1.00000000001334 1.33424330611698e-11 1 0 0 65 7176 ko04150 mTOR signaling pathway 1.00000000001336 1.33646262121633e-11 144 0 0 65 7176 rno04150 mTOR signaling pathway 1.00000000001336 1.33646262121633e-11 144 0 0 65 7176 rno04064 NF-kappa B signaling pathway 1.0000000000135 1.35023186156559e-11 79 0 0 65 7176 ko04064 NF-kappa B signaling pathway 1.0000000000135 1.35023186156559e-11 79 0 0 65 7176 ko04650 Natural killer cell mediated cytotoxicity 1.0000000000136 1.3603391923887e-11 86 0 0 65 7176 ko04620 Toll-like receptor signaling pathway 1.0000000000136 1.3603391923887e-11 86 0 0 65 7176 rno04650 Natural killer cell mediated cytotoxicity 1.0000000000136 1.3603391923887e-11 86 0 0 65 7176 rno04658 Th1 and Th2 cell differentiation 1.0000000000136 1.3603391923887e-11 86 0 0 65 7176 rno04620 Toll-like receptor signaling pathway 1.0000000000136 1.3603391923887e-11 86 0 0 65 7176 ko04658 Th1 and Th2 cell differentiation 1.0000000000136 1.3603391923887e-11 86 0 0 65 7176 ko04622 RIG-I-like receptor signaling pathway 1.00000000001382 1.38228952480855e-11 57 0 0 65 7176 rno05210 Colorectal cancer 1.00000000001382 1.38228952480855e-11 57 0 0 65 7176 ko05210 Colorectal cancer 1.00000000001382 1.38228952480855e-11 57 0 0 65 7176 rno04622 RIG-I-like receptor signaling pathway 1.00000000001382 1.38228952480855e-11 57 0 0 65 7176 ko00240 Pyrimidine metabolism 1.000000000014 1.39972115113859e-11 94 0 0 65 7176 rno00240 Pyrimidine metabolism 1.000000000014 1.39972115113859e-11 94 0 0 65 7176 rno04380 Osteoclast differentiation 1.00000000001404 1.40355660576801e-11 118 0 0 65 7176 ko04380 Osteoclast differentiation 1.00000000001404 1.40355660576801e-11 118 0 0 65 7176 ko01524 Platinum drug resistance 1.00000000001416 1.41612669719139e-11 75 0 0 65 7176 rno01524 Platinum drug resistance 1.00000000001416 1.41612669719139e-11 75 0 0 65 7176 ko05322 Systemic lupus erythematosus 1.00000000001416 1.41612669719139e-11 75 0 0 65 7176 rno05322 Systemic lupus erythematosus 1.00000000001416 1.41612669719139e-11 75 0 0 65 7176 ko04520 Adherens junction 1.00000000001429 1.42891647969533e-11 64 0 0 65 7176 rno04520 Adherens junction 1.00000000001429 1.42891647969533e-11 64 0 0 65 7176 ko04612 Antigen processing and presentation 1.00000000001444 1.4441631484276e-11 88 0 0 65 7176 rno01522 Endocrine resistance 1.00000000001444 1.4441631484276e-11 88 0 0 65 7176 rno04612 Antigen processing and presentation 1.00000000001444 1.4441631484276e-11 88 0 0 65 7176 ko01522 Endocrine resistance 1.00000000001444 1.4441631484276e-11 88 0 0 65 7176 rno05211 Renal cell carcinoma 1.00000000001448 1.44838777642015e-11 60 0 0 65 7176 ko05211 Renal cell carcinoma 1.00000000001448 1.44838777642015e-11 60 0 0 65 7176 ko05332 Graft-versus-host disease 1.00000000001448 1.44838777642015e-11 60 0 0 65 7176 ko04213 Longevity regulating pathway - multiple species 1.00000000001448 1.44838777642015e-11 60 0 0 65 7176 rno05332 Graft-versus-host disease 1.00000000001448 1.44838777642015e-11 60 0 0 65 7176 rno04213 Longevity regulating pathway - multiple species 1.00000000001448 1.44838777642015e-11 60 0 0 65 7176 M00677 Wnt signaling 1.00000000001483 1.48328240652136e-11 36 0 0 65 7176 M00427 Nuclear pore complex 1.00000000001483 1.48328240652136e-11 36 0 0 65 7176 rno_M00677 Wnt signaling 1.00000000001483 1.48328240652136e-11 36 0 0 65 7176 rno_M00427 Nuclear pore complex 1.00000000001483 1.48328240652136e-11 36 0 0 65 7176 M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 1.00000000001483 1.48328240652136e-11 36 0 0 65 7176 rno_M00359 Aminoacyl-tRNA biosynthesis, eukaryotes 1.00000000001483 1.48328240652136e-11 36 0 0 65 7176 rno05212 Pancreatic cancer 1.00000000001495 1.49542429779215e-11 61 0 0 65 7176 ko05212 Pancreatic cancer 1.00000000001495 1.49542429779215e-11 61 0 0 65 7176 rno04137 Mitophagy - animal 1.00000000001495 1.49542429779215e-11 61 0 0 65 7176 ko05230 Central carbon metabolism in cancer 1.00000000001495 1.49542429779215e-11 61 0 0 65 7176 rno05230 Central carbon metabolism in cancer 1.00000000001495 1.49542429779215e-11 61 0 0 65 7176 ko04137 Mitophagy - animal 1.00000000001495 1.49542429779215e-11 61 0 0 65 7176 rno04146 Peroxisome 1.00000000001525 1.52468788569141e-11 81 0 0 65 7176 ko04914 Progesterone-mediated oocyte maturation 1.00000000001525 1.52468788569141e-11 81 0 0 65 7176 rno05323 Rheumatoid arthritis 1.00000000001525 1.52468788569141e-11 81 0 0 65 7176 rno04914 Progesterone-mediated oocyte maturation 1.00000000001525 1.52468788569141e-11 81 0 0 65 7176 ko04146 Peroxisome 1.00000000001525 1.52468788569141e-11 81 0 0 65 7176 ko05323 Rheumatoid arthritis 1.00000000001525 1.52468788569141e-11 81 0 0 65 7176 M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00380 SCF-BTRC complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00405 THC complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00405 THC complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00382 SCF-FBS complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00289 RF-C complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00383 ECV complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00079 Keratan sulfate degradation 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00044 Tyrosine degradation, tyrosine => homogentisate 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00386 Cul4-DDB1-CSA complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00079 Keratan sulfate degradation 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00307 Pyruvate oxidation, pyruvate => acetyl-CoA 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00383 ECV complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00385 Cul4-DDB1-DDB2 complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00386 Cul4-DDB1-CSA complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00289 RF-C complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno00400 Phenylalanine, tyrosine and tryptophan biosynthesis 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 M00380 SCF-BTRC complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00044 Tyrosine degradation, tyrosine => homogentisate 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00385 Cul4-DDB1-DDB2 complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00382 SCF-FBS complex 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno_M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone 1.0000000000153 1.52998252938857e-11 5 0 0 65 7176 rno04915 Estrogen signaling pathway 1.00000000001628 1.62793176683488e-11 92 0 0 65 7176 ko04915 Estrogen signaling pathway 1.00000000001628 1.62793176683488e-11 92 0 0 65 7176 rno05166 HTLV-I infection 1.0000000000163 1.62962670663009e-11 267 0 0 65 7176 ko05166 HTLV-I infection 1.0000000000163 1.62962670663009e-11 267 0 0 65 7176 ko05168 Herpes simplex infection 1.00000000001635 1.63499847276235e-11 187 0 0 65 7176 rno05168 Herpes simplex infection 1.00000000001635 1.63499847276235e-11 187 0 0 65 7176 ko04071 Sphingolipid signaling pathway 1.00000000001662 1.66247899305599e-11 116 0 0 65 7176 ko04142 Lysosome 1.00000000001662 1.66247899305599e-11 116 0 0 65 7176 rno04142 Lysosome 1.00000000001662 1.66247899305599e-11 116 0 0 65 7176 rno04071 Sphingolipid signaling pathway 1.00000000001662 1.66247899305599e-11 116 0 0 65 7176 rno01521 EGFR tyrosine kinase inhibitor resistance 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 rno05132 Salmonella infection 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 ko04610 Complement and coagulation cascades 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 rno00140 Steroid hormone biosynthesis 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 ko00140 Steroid hormone biosynthesis 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 rno00830 Retinol metabolism 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 ko05132 Salmonella infection 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 ko00830 Retinol metabolism 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 rno04610 Complement and coagulation cascades 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 ko01521 EGFR tyrosine kinase inhibitor resistance 1.000000000017 1.69990386413727e-11 77 0 0 65 7176 ko05224 Breast cancer 1.00000000001744 1.74384167718901e-11 136 0 0 65 7176 rno05224 Breast cancer 1.00000000001744 1.74384167718901e-11 136 0 0 65 7176 M00686 Toll-like receptor signaling 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno_M00089 Triacylglycerol biosynthesis 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 M00099 Sphingosine biosynthesis 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno_M00158 F-type ATPase, eukaryotes 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno_M00181 RNA polymerase III, eukaryotes 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 M00158 F-type ATPase, eukaryotes 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno_M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno_M00099 Sphingosine biosynthesis 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 M00181 RNA polymerase III, eukaryotes 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno_M00686 Toll-like receptor signaling 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 rno00603 Glycosphingolipid biosynthesis - globo and isoglobo series 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 M00089 Triacylglycerol biosynthesis 1.00000000001762 1.76192853180247e-11 15 0 0 65 7176 ko00650 Butanoate metabolism 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 M00354 Spliceosome, U4/U6.U5 tri-snRNP 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno_M00354 Spliceosome, U4/U6.U5 tri-snRNP 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno05216 Thyroid cancer 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko00053 Ascorbate and aldarate metabolism 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno03020 RNA polymerase 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko04950 Maturity onset diabetes of the young 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno_M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko03020 RNA polymerase 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno00062 Fatty acid elongation 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno00630 Glyoxylate and dicarboxylate metabolism 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno04950 Maturity onset diabetes of the young 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko05216 Thyroid cancer 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko00062 Fatty acid elongation 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno00053 Ascorbate and aldarate metabolism 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko00630 Glyoxylate and dicarboxylate metabolism 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 rno00650 Butanoate metabolism 1.00000000001768 1.76811944855422e-11 26 0 0 65 7176 ko04933 AGE-RAGE signaling pathway in diabetic complications 1.00000000001786 1.78553419820012e-11 96 0 0 65 7176 rno04933 AGE-RAGE signaling pathway in diabetic complications 1.00000000001786 1.78553419820012e-11 96 0 0 65 7176 ko04141 Protein processing in endoplasmic reticulum 1.00000000001926 1.92563966473737e-11 155 0 0 65 7176 rno04141 Protein processing in endoplasmic reticulum 1.00000000001926 1.92563966473737e-11 155 0 0 65 7176 rno04621 NOD-like receptor signaling pathway 1.00000000001957 1.95656437451105e-11 137 0 0 65 7176 ko04621 NOD-like receptor signaling pathway 1.00000000001957 1.95656437451105e-11 137 0 0 65 7176 rno05100 Bacterial invasion of epithelial cells 1.00000000002013 2.01272378155788e-11 73 0 0 65 7176 ko05100 Bacterial invasion of epithelial cells 1.00000000002013 2.01272378155788e-11 73 0 0 65 7176 ko05206 MicroRNAs in cancer 1.00000000002074 2.07425265078871e-11 247 0 0 65 7176 rno05206 MicroRNAs in cancer 1.00000000002074 2.07425265078871e-11 247 0 0 65 7176 rno04210 Apoptosis 1.00000000002434 2.43439876883146e-11 129 0 0 65 7176 ko04210 Apoptosis 1.00000000002434 2.43439876883146e-11 129 0 0 65 7176 ko03013 RNA transport 1.00000000002748 2.7479058756256e-11 149 0 0 65 7176 rno03013 RNA transport 1.00000000002748 2.7479058756256e-11 149 0 0 65 7176