Gene to GO MF test for over-representation
GOMFID Pvalue OddsRatio ExpCount Count Size Term
GO:0005488 0.00000 1.67959 1664 1935 10492 binding
GO:0140110 0.00000 2.00262 168 279 1058 transcription regulator activity
GO:0140096 0.00000 1.60224 357 494 2249 catalytic activity, acting on a protein
GO:0001067 0.00000 2.53559 67 134 423 regulatory region nucleic acid binding
GO:0044212 0.00000 2.51571 67 133 422 transcription regulatory region DNA binding
GO:1901363 0.00000 1.41031 869 1047 5479 heterocyclic compound binding
GO:0097159 0.00000 1.40810 877 1055 5530 organic cyclic compound binding
GO:0003700 0.00000 1.88429 140 224 880 DNA-binding transcription factor activity
GO:0043167 0.00000 1.36829 937 1105 5912 ion binding
GO:0003677 0.00000 1.59690 268 376 1693 DNA binding
GO:0030695 0.00000 2.98769 33 73 205 GTPase regulator activity
GO:0097153 0.00000 24.03139 3 18 22 cysteine-type endopeptidase activity involved in apoptotic process
GO:0005096 0.00000 2.95526 31 69 195 GTPase activator activity
GO:0005515 0.00000 1.37894 583 715 3679 protein binding
GO:0003682 0.00000 2.75563 35 74 219 chromatin binding
GO:0060589 0.00000 2.64504 36 74 225 nucleoside-triphosphatase regulator activity
GO:0008047 0.00000 2.35557 48 91 300 enzyme activator activity
GO:0003676 0.00000 1.38392 495 613 3119 nucleic acid binding
GO:0003713 0.00000 3.66190 18 45 111 transcription coactivator activity
GO:0000976 0.00000 2.18721 55 99 344 transcription regulatory region sequence-specific DNA binding
GO:0003712 0.00000 2.47033 38 76 242 transcription coregulator activity
GO:0032452 0.00000 17.07528 3 16 21 histone demethylase activity
GO:1990837 0.00000 2.05628 58 100 363 sequence-specific double-stranded DNA binding
GO:0003690 0.00000 1.95521 68 113 426 double-stranded DNA binding
GO:0097199 0.00000 Inf 2 10 10 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0035639 0.00000 1.38970 338 427 2132 purine ribonucleoside triphosphate binding
GO:0005524 0.00000 1.43796 261 340 1644 ATP binding
GO:0032559 0.00000 1.43077 267 347 1685 adenyl ribonucleotide binding
GO:0004197 0.00000 3.18595 17 41 110 cysteine-type endopeptidase activity
GO:0030554 0.00000 1.42607 268 347 1689 adenyl nucleotide binding
GO:0046872 0.00000 1.30669 557 662 3512 metal ion binding
GO:0032555 0.00000 1.37193 347 434 2188 purine ribonucleotide binding
GO:0000981 0.00000 1.81005 78 123 491 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0043168 0.00000 1.33513 435 530 2744 anion binding
GO:0004715 0.00000 5.59629 7 22 43 non-membrane spanning protein tyrosine kinase activity
GO:0017076 0.00000 1.36750 348 434 2193 purine nucleotide binding
GO:0001012 0.00000 2.09902 46 81 289 RNA polymerase II regulatory region DNA binding
GO:0097367 0.00000 1.35723 366 454 2310 carbohydrate derivative binding
GO:0032553 0.00000 1.36506 349 435 2201 ribonucleotide binding
GO:0043169 0.00000 1.29222 569 671 3588 cation binding
GO:0042393 0.00000 3.16019 15 36 97 histone binding
GO:0008144 0.00000 1.38230 284 359 1789 drug binding
GO:0032451 0.00000 7.75829 4 16 27 demethylase activity
GO:0000977 0.00000 2.03889 45 78 284 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0016740 0.00000 1.32868 387 472 2441 transferase activity
GO:0008234 0.00000 2.33682 30 57 188 cysteine-type peptidase activity
GO:0032454 0.00000 47.91438 2 9 10 histone demethylase activity (H3-K9 specific)
GO:0000166 0.00000 1.31434 375 455 2368 nucleotide binding
GO:1901265 0.00000 1.31434 375 455 2368 nucleoside phosphate binding
GO:0008270 0.00000 1.54393 119 166 749 zinc ion binding
GO:0030234 0.00000 1.58558 100 143 631 enzyme regulator activity
GO:0016773 0.00000 1.47552 144 194 908 phosphotransferase activity, alcohol group as acceptor
GO:0000987 0.00001 2.38069 23 44 143 proximal promoter sequence-specific DNA binding
GO:0004672 0.00001 1.49473 128 174 805 protein kinase activity
GO:0004842 0.00001 1.89528 44 73 280 ubiquitin-protein transferase activity
GO:0019899 0.00001 1.54127 107 149 672 enzyme binding
GO:0000978 0.00001 2.37401 22 43 140 RNA polymerase II proximal promoter sequence-specific DNA binding
GO:0016772 0.00001 1.40334 185 239 1166 transferase activity, transferring phosphorus-containing groups
GO:0019904 0.00001 2.75742 15 33 97 protein domain specific binding
GO:0016301 0.00001 1.42487 163 214 1030 kinase activity
GO:0019787 0.00001 1.84892 46 75 293 ubiquitin-like protein transferase activity
GO:0043565 0.00001 1.47398 130 176 823 sequence-specific DNA binding
GO:0008134 0.00001 1.95193 38 64 240 transcription factor binding
GO:0030374 0.00001 4.36394 6 18 40 nuclear receptor transcription coactivator activity
GO:0036094 0.00001 1.26568 415 489 2619 small molecule binding
GO:0051020 0.00002 1.72669 57 87 358 GTPase binding
GO:0035091 0.00002 2.25685 23 43 145 phosphatidylinositol binding
GO:0098772 0.00002 1.37791 187 239 1182 molecular function regulator
GO:0015923 0.00003 8.87323 3 10 16 mannosidase activity
GO:0017056 0.00003 7.32209 3 11 19 structural constituent of nuclear pore
GO:0017016 0.00008 1.74683 45 70 285 Ras GTPase binding
GO:0004713 0.00009 2.22266 20 37 126 protein tyrosine kinase activity
GO:0008009 0.00009 3.23247 8 20 53 chemokine activity
GO:0042379 0.00009 3.23247 8 20 53 chemokine receptor binding
GO:0071558 0.00010 31.90789 1 6 7 histone demethylase activity (H3-K27 specific)
GO:0004185 0.00010 Inf 1 5 5 serine-type carboxypeptidase activity
GO:0017124 0.00012 5.85687 3 11 21 SH3 domain binding
GO:0003824 0.00012 1.17301 958 1043 6042 catalytic activity
GO:0004559 0.00013 7.98299 2 9 15 alpha-mannosidase activity
GO:0008238 0.00013 2.45819 15 29 92 exopeptidase activity
GO:0031267 0.00015 1.70654 46 70 290 small GTPase binding
GO:0046914 0.00018 1.35252 159 201 1005 transition metal ion binding
GO:0061630 0.00019 2.12647 21 37 130 ubiquitin protein ligase activity
GO:0061659 0.00019 2.12647 21 37 130 ubiquitin-like protein ligase activity
GO:0004553 0.00023 2.32173 16 30 99 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005126 0.00023 2.01122 24 41 150 cytokine receptor binding
GO:0004177 0.00028 3.63261 6 15 37 aminopeptidase activity
GO:0140030 0.00028 2.79981 10 21 61 modification-dependent protein binding
GO:0035064 0.00032 4.07264 5 13 30 methylated histone binding
GO:0140034 0.00032 4.07264 5 13 30 methylation-dependent protein binding
GO:0004571 0.00033 15.95285 1 6 8 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0015924 0.00033 15.95285 1 6 8 mannosyl-oligosaccharide mannosidase activity
GO:0042054 0.00040 2.89391 9 19 54 histone methyltransferase activity
GO:0005201 0.00050 2.73404 9 20 59 extracellular matrix structural constituent
GO:0018024 0.00054 3.32944 6 15 39 histone-lysine N-methyltransferase activity
GO:0008235 0.00073 2.92205 8 17 48 metalloexopeptidase activity
GO:0070008 0.00086 10.63450 1 6 9 serine-type exopeptidase activity
GO:0004879 0.00091 2.74059 8 18 53 nuclear receptor activity
GO:0098531 0.00091 2.74059 8 18 53 transcription factor activity, direct ligand regulated sequence-specific DNA binding
GO:0004674 0.00096 1.42234 85 112 535 protein serine/threonine kinase activity
GO:0004843 0.00109 2.59638 9 19 58 thiol-dependent ubiquitin-specific protease activity
GO:0003707 0.00119 2.31393 12 23 76 steroid hormone receptor activity
GO:0005125 0.00122 1.98610 19 32 118 cytokine activity
GO:0004180 0.00129 3.54896 5 12 30 carboxypeptidase activity
GO:0004402 0.00129 2.84099 7 16 46 histone acetyltransferase activity
GO:0070011 0.00138 1.37955 96 124 607 peptidase activity, acting on L-amino acid peptides
GO:0016798 0.00142 1.96313 19 32 119 hydrolase activity, acting on glycosyl bonds
GO:0016278 0.00167 2.74915 7 16 47 lysine N-methyltransferase activity
GO:0016279 0.00167 2.74915 7 16 47 protein-lysine N-methyltransferase activity
GO:0061733 0.00167 2.74915 7 16 47 peptide-lysine-N-acetyltransferase activity
GO:0046332 0.00180 3.36194 5 12 31 SMAD binding
GO:0017048 0.00181 1.79547 25 39 155 Rho GTPase binding
GO:0004725 0.00220 1.89730 19 32 122 protein tyrosine phosphatase activity
GO:0008233 0.00227 1.35081 100 127 632 peptidase activity
GO:0019955 0.00232 2.45883 9 18 57 cytokine binding
GO:0032453 0.00276 21.25639 1 4 5 histone demethylase activity (H3-K4 specific)
GO:0070006 0.00298 3.98985 3 9 21 metalloaminopeptidase activity
GO:0052742 0.00305 5.31773 2 7 14 phosphatidylinositol kinase activity
GO:0044877 0.00320 1.41494 68 89 426 protein-containing complex binding
GO:0003779 0.00350 1.44492 58 78 367 actin binding
GO:0004560 0.00398 Inf 0 3 3 alpha-L-fucosidase activity
GO:0004904 0.00398 Inf 0 3 3 interferon receptor activity
GO:0015928 0.00398 Inf 0 3 3 fucosidase activity
GO:0034647 0.00398 Inf 0 3 3 histone demethylase activity (H3-trimethyl-K4 specific)
GO:0035325 0.00398 Inf 0 3 3 Toll-like receptor binding
GO:0035575 0.00398 Inf 0 3 3 histone demethylase activity (H4-K20 specific)
GO:0050700 0.00398 Inf 0 3 3 CARD domain binding
GO:0070579 0.00398 Inf 0 3 3 methylcytosine dioxygenase activity
GO:0008276 0.00447 2.11117 12 21 74 protein methyltransferase activity
GO:0016787 0.00488 1.16263 397 442 2506 hydrolase activity
GO:0004712 0.00495 4.65270 2 7 15 protein serine/threonine/tyrosine kinase activity
GO:0008139 0.00495 4.65270 2 7 15 nuclear localization sequence binding
GO:0031490 0.00528 2.36651 8 16 52 chromatin DNA binding
GO:0003723 0.00578 1.27022 130 157 821 RNA binding
GO:0048365 0.00605 2.92642 5 11 31 Rac GTPase binding
GO:0005085 0.00606 1.61285 29 42 181 guanyl-nucleotide exchange factor activity
GO:0048020 0.00613 3.41940 4 9 23 CCR chemokine receptor binding
GO:0003714 0.00705 1.84770 16 26 101 transcription corepressor activity
GO:0004896 0.00706 2.04869 11 20 72 cytokine receptor activity
GO:0001227 0.00711 1.82178 17 27 106 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0048185 0.00718 6.64368 1 5 9 activin binding
GO:0004711 0.00722 10.62747 1 4 6 ribosomal protein S6 kinase activity
GO:0008190 0.00722 10.62747 1 4 6 eukaryotic initiation factor 4E binding
GO:0043995 0.00722 10.62747 1 4 6 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 0.00722 10.62747 1 4 6 histone acetyltransferase activity (H4-K8 specific)
GO:0034212 0.00787 2.24165 9 16 54 peptide N-acetyltransferase activity
GO:0004012 0.00845 3.19122 4 9 24 phospholipid-translocating ATPase activity
GO:0008374 0.00945 2.55402 6 12 37 O-acyltransferase activity
GO:0070530 0.01250 5.31458 2 5 10 K63-linked polyubiquitin modification-dependent protein binding
GO:0016747 0.01330 1.50487 32 44 200 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0036459 0.01334 1.86397 13 21 81 thiol-dependent ubiquitinyl hydrolase activity
GO:0101005 0.01334 1.86397 13 21 81 ubiquitinyl hydrolase activity
GO:0019783 0.01353 1.80164 14 23 91 ubiquitin-like protein-specific protease activity
GO:0001221 0.01404 15.93647 1 3 4 transcription cofactor binding
GO:0001222 0.01404 15.93647 1 3 4 transcription corepressor binding
GO:0001968 0.01404 15.93647 1 3 4 fibronectin binding
GO:0004694 0.01404 15.93647 1 3 4 eukaryotic translation initiation factor 2alpha kinase activity
GO:0005220 0.01404 15.93647 1 3 4 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005351 0.01404 15.93647 1 3 4 carbohydrate:proton symporter activity
GO:0034450 0.01404 15.93647 1 3 4 ubiquitin-ubiquitin ligase activity
GO:0035035 0.01404 15.93647 1 3 4 histone acetyltransferase binding
GO:0055056 0.01404 15.93647 1 3 4 D-glucose transmembrane transporter activity
GO:0004530 0.01475 7.08449 1 4 7 deoxyribonuclease I activity
GO:0008239 0.01475 7.08449 1 4 7 dipeptidyl-peptidase activity
GO:0035005 0.01475 7.08449 1 4 7 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0046972 0.01475 7.08449 1 4 7 histone acetyltransferase activity (H4-K16 specific)
GO:0008170 0.01494 1.90870 11 19 72 N-methyltransferase activity
GO:0016407 0.01540 1.80256 14 22 87 acetyltransferase activity
GO:0035257 0.01570 3.03835 3 8 22 nuclear hormone receptor binding
GO:0001103 0.01584 3.38308 3 7 18 RNA polymerase II repressing transcription factor binding
GO:0016409 0.01615 2.23123 7 13 44 palmitoyltransferase activity
GO:0070491 0.01942 2.65880 4 9 27 repressing transcription factor binding
GO:0017137 0.01957 1.70431 16 24 99 Rab GTPase binding
GO:0002039 0.01995 4.42851 2 5 11 p53 binding
GO:0015149 0.01995 4.42851 2 5 11 hexose transmembrane transporter activity
GO:0016411 0.01995 4.42851 2 5 11 acylglycerol O-acyltransferase activity
GO:0019706 0.02016 2.34033 6 11 36 protein-cysteine S-palmitoyltransferase activity
GO:0019707 0.02016 2.34033 6 11 36 protein-cysteine S-acyltransferase activity
GO:0016493 0.02079 2.83560 4 8 23 C-C chemokine receptor activity
GO:0019957 0.02079 2.83560 4 8 23 C-C chemokine binding
GO:0017017 0.02174 3.54337 2 6 15 MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0033549 0.02174 3.54337 2 6 15 MAP kinase phosphatase activity
GO:0004386 0.02199 1.68177 16 24 100 helicase activity
GO:0008080 0.02268 1.84247 11 18 70 N-acetyltransferase activity
GO:0005543 0.02350 1.38529 42 54 262 phospholipid binding
GO:0015144 0.02470 2.51869 4 9 28 carbohydrate transmembrane transporter activity
GO:0031683 0.02470 2.51869 4 9 28 G-protein beta/gamma-subunit complex binding
GO:0003720 0.02513 Inf 0 2 2 telomerase activity
GO:0003827 0.02513 Inf 0 2 2 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
GO:0003964 0.02513 Inf 0 2 2 RNA-directed DNA polymerase activity
GO:0004301 0.02513 Inf 0 2 2 epoxide hydrolase activity
GO:0004335 0.02513 Inf 0 2 2 galactokinase activity
GO:0004531 0.02513 Inf 0 2 2 deoxyribonuclease II activity
GO:0004886 0.02513 Inf 0 2 2 9-cis retinoic acid receptor activity
GO:0005094 0.02513 Inf 0 2 2 Rho GDP-dissociation inhibitor activity
GO:0005173 0.02513 Inf 0 2 2 stem cell factor receptor binding
GO:0005534 0.02513 Inf 0 2 2 galactose binding
GO:0008119 0.02513 Inf 0 2 2 thiopurine S-methyltransferase activity
GO:0010385 0.02513 Inf 0 2 2 double-stranded methylated DNA binding
GO:0032090 0.02513 Inf 0 2 2 Pyrin domain binding
GO:0033897 0.02513 Inf 0 2 2 ribonuclease T2 activity
GO:0034648 0.02513 Inf 0 2 2 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0044729 0.02513 Inf 0 2 2 hemi-methylated DNA-binding
GO:0047192 0.02513 Inf 0 2 2 1-alkylglycerophosphocholine O-acetyltransferase activity
GO:0003708 0.02583 5.31300 1 4 8 retinoic acid receptor activity
GO:0003841 0.02583 5.31300 1 4 8 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005402 0.02583 5.31300 1 4 8 carbohydrate:cation symporter activity
GO:0008329 0.02583 5.31300 1 4 8 signaling pattern recognition receptor activity
GO:0016176 0.02583 5.31300 1 4 8 superoxide-generating NADPH oxidase activator activity
GO:0038187 0.02583 5.31300 1 4 8 pattern recognition receptor activity
GO:0042171 0.02583 5.31300 1 4 8 lysophosphatidic acid acyltransferase activity
GO:0061980 0.02583 5.31300 1 4 8 regulatory RNA binding
GO:0071617 0.02583 5.31300 1 4 8 lysophospholipid acyltransferase activity
GO:0019956 0.02696 2.65819 4 8 24 chemokine binding
GO:0008289 0.02736 1.29108 65 80 411 lipid binding
GO:0001664 0.02890 1.50282 24 33 150 G protein-coupled receptor binding
GO:0016894 0.02982 3.79561 2 5 12 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
GO:0042056 0.02982 3.79561 2 5 12 chemoattractant activity
GO:0016417 0.02992 2.16667 6 11 38 S-acyltransferase activity
GO:0004367 0.03096 7.96769 1 3 5 glycerol-3-phosphate dehydrogenase [NAD+] activity
GO:0004430 0.03096 7.96769 1 3 5 1-phosphatidylinositol 4-kinase activity
GO:0004514 0.03096 7.96769 1 3 5 nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0005159 0.03096 7.96769 1 3 5 insulin-like growth factor receptor binding
GO:0016715 0.03096 7.96769 1 3 5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
GO:0016893 0.03382 2.21556 5 10 34 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
GO:0005048 0.03430 2.50166 4 8 25 signal sequence binding
GO:0005164 0.03430 2.50166 4 8 25 tumor necrosis factor receptor binding
GO:0032813 0.03430 2.50166 4 8 25 tumor necrosis factor receptor superfamily binding
GO:0003729 0.03434 1.47735 24 33 152 mRNA binding
GO:0005518 0.03765 2.65759 3 7 21 collagen binding
GO:0008013 0.03814 2.27850 5 9 30 beta-catenin binding
GO:0045182 0.03814 2.27850 5 9 30 translation regulator activity
GO:0000982 0.03939 1.43135 27 36 170 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
GO:0010485 0.04059 2.89872 3 6 17 H4 histone acetyltransferase activity
GO:0035014 0.04059 2.89872 3 6 17 phosphatidylinositol 3-kinase regulator activity
GO:0004415 0.04075 4.25011 1 4 9 hyalurononglucosaminidase activity
GO:0004652 0.04075 4.25011 1 4 9 polynucleotide adenylyltransferase activity
GO:0004720 0.04075 4.25011 1 4 9 protein-lysine 6-oxidase activity
GO:0004887 0.04075 4.25011 1 4 9 thyroid hormone receptor activity
GO:0005070 0.04075 4.25011 1 4 9 SH3/SH2 adaptor activity
GO:0008525 0.04075 4.25011 1 4 9 phosphatidylcholine transporter activity
GO:0016303 0.04075 4.25011 1 4 9 1-phosphatidylinositol-3-kinase activity
GO:0035004 0.04075 4.25011 1 4 9 phosphatidylinositol 3-kinase activity
GO:0035258 0.04075 4.25011 1 4 9 steroid hormone receptor binding
GO:0042800 0.04075 4.25011 1 4 9 histone methyltransferase activity (H3-K4 specific)
GO:0050664 0.04075 4.25011 1 4 9 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
GO:1990841 0.04075 4.25011 1 4 9 promoter-specific chromatin binding
GO:0015145 0.04227 3.32093 2 5 13 monosaccharide transmembrane transporter activity
GO:0031369 0.04227 3.32093 2 5 13 translation initiation factor binding
GO:0003950 0.04643 2.17478 5 9 31 NAD+ ADP-ribosyltransferase activity
GO:0004721 0.04881 1.37494 31 40 195 phosphoprotein phosphatase activity