Gene to GO MF test for over-representation
GOMFID Pvalue OddsRatio ExpCount Count Size Term
GO:0015075 0.00000 2.79754 195 375 875 ion transmembrane transporter activity
GO:0015318 0.00000 2.81776 185 359 833 inorganic molecular entity transmembrane transporter activity
GO:0008324 0.00000 3.16730 141 292 632 cation transmembrane transporter activity
GO:0022839 0.00000 4.61819 75 188 336 ion gated channel activity
GO:0022836 0.00000 4.47678 77 192 348 gated channel activity
GO:0022857 0.00000 2.45618 246 437 1104 transmembrane transporter activity
GO:0022838 0.00000 3.80627 99 226 443 substrate-specific channel activity
GO:0005216 0.00000 3.86131 96 222 432 ion channel activity
GO:0015267 0.00000 3.62653 105 234 470 channel activity
GO:0022803 0.00000 3.62653 105 234 470 passive transmembrane transporter activity
GO:0022890 0.00000 3.18162 132 276 595 inorganic cation transmembrane transporter activity
GO:0005261 0.00000 4.53058 73 181 326 cation channel activity
GO:0005215 0.00000 2.22926 278 467 1252 transporter activity
GO:0046873 0.00000 3.22350 95 200 425 metal ion transmembrane transporter activity
GO:0015276 0.00000 5.20642 34 92 155 ligand-gated ion channel activity
GO:0022834 0.00000 5.20642 34 92 155 ligand-gated channel activity
GO:0015077 0.00000 2.93673 85 172 383 monovalent inorganic cation transmembrane transporter activity
GO:0005230 0.00000 8.36786 21 66 94 extracellular ligand-gated ion channel activity
GO:0005509 0.00000 2.21670 148 253 667 calcium ion binding
GO:0022843 0.00000 4.52699 35 89 159 voltage-gated cation channel activity
GO:0022832 0.00000 3.91195 43 102 195 voltage-gated channel activity
GO:0022824 0.00000 10.83288 14 49 65 transmitter-gated ion channel activity
GO:0022835 0.00000 10.83288 14 49 65 transmitter-gated channel activity
GO:0005244 0.00000 3.87515 43 100 192 voltage-gated ion channel activity
GO:0008066 0.00000 29.97521 8 34 38 glutamate receptor activity
GO:0030594 0.00000 4.45530 32 79 142 neurotransmitter receptor activity
GO:0015085 0.00000 4.57956 28 71 126 calcium ion transmembrane transporter activity
GO:0099094 0.00000 4.92990 24 64 110 ligand-gated cation channel activity
GO:0015079 0.00000 3.47683 40 89 180 potassium ion transmembrane transporter activity
GO:0004970 0.00000 45.75524 6 26 28 ionotropic glutamate receptor activity
GO:0005267 0.00000 3.93292 30 71 135 potassium channel activity
GO:0005262 0.00000 4.13634 23 55 102 calcium channel activity
GO:0005515 0.00000 1.32708 818 966 3679 protein binding
GO:0015081 0.00000 3.18806 30 64 135 sodium ion transmembrane transporter activity
GO:0005249 0.00000 3.67235 23 52 102 voltage-gated potassium channel activity
GO:0030545 0.00000 2.08199 77 127 344 receptor regulator activity
GO:0048018 0.00000 2.04294 75 123 337 receptor ligand activity
GO:0022804 0.00000 1.99331 74 119 331 active transmembrane transporter activity
GO:0005245 0.00000 5.36950 11 29 48 voltage-gated calcium channel activity
GO:0070405 0.00000 4.74265 12 31 54 ammonium ion binding
GO:0008092 0.00000 1.62722 143 202 645 cytoskeletal protein binding
GO:0005179 0.00000 2.91173 26 52 115 hormone activity
GO:0005231 0.00000 5.85885 9 25 40 excitatory extracellular ligand-gated ion channel activity
GO:0042165 0.00000 4.92347 11 28 48 neurotransmitter binding
GO:0005516 0.00000 3.43363 18 39 79 calmodulin binding
GO:0098960 0.00000 6.44112 8 22 34 postsynaptic neurotransmitter receptor activity
GO:0008528 0.00000 2.39129 35 63 156 G protein-coupled peptide receptor activity
GO:0016491 0.00000 1.51971 173 232 777 oxidoreductase activity
GO:0005102 0.00000 1.54053 157 213 706 signaling receptor binding
GO:0038023 0.00000 1.37931 290 362 1304 signaling receptor activity
GO:0009055 0.00000 3.51796 15 33 66 electron transfer activity
GO:0005272 0.00000 10.52623 4 15 20 sodium channel activity
GO:0072341 0.00000 5.67348 8 21 34 modified amino acid binding
GO:0001653 0.00000 2.23608 37 64 165 peptide receptor activity
GO:0099529 0.00000 5.85250 7 20 32 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
GO:1904315 0.00000 5.85250 7 20 32 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:0060089 0.00000 1.36448 296 367 1332 molecular transducer activity
GO:0051015 0.00000 2.11787 41 69 184 actin filament binding
GO:0042923 0.00000 8.77121 5 15 21 neuropeptide binding
GO:0008188 0.00000 3.64944 12 27 53 neuropeptide receptor activity
GO:0042802 0.00000 1.95597 48 77 216 identical protein binding
GO:0004888 0.00000 1.37075 252 314 1133 transmembrane signaling receptor activity
GO:0008289 0.00001 1.63914 91 130 411 lipid binding
GO:0004972 0.00001 Inf 2 8 8 NMDA glutamate receptor activity
GO:0005544 0.00001 3.39322 13 28 57 calcium-dependent phospholipid binding
GO:0019905 0.00001 3.83188 10 24 46 syntaxin binding
GO:0015464 0.00001 5.26450 7 18 30 acetylcholine receptor activity
GO:0042562 0.00001 3.27987 13 28 58 hormone binding
GO:0004935 0.00001 6.57743 5 15 23 adrenergic receptor activity
GO:0022848 0.00001 6.57743 5 15 23 acetylcholine-gated cation-selective channel activity
GO:0015291 0.00002 1.91181 45 71 202 secondary active transmembrane transporter activity
GO:0015491 0.00002 5.61337 6 16 26 cation:cation antiporter activity
GO:0042166 0.00002 7.59775 4 13 19 acetylcholine binding
GO:0033218 0.00002 2.16380 30 51 134 amide binding
GO:0001786 0.00003 5.84617 5 15 24 phosphatidylserine binding
GO:0015368 0.00003 8.41440 4 12 17 calcium:cation antiporter activity
GO:0042578 0.00003 1.59440 85 119 383 phosphoric ester hydrolase activity
GO:0008083 0.00003 2.20579 27 47 122 growth factor activity
GO:0004936 0.00004 28.02710 2 8 9 alpha-adrenergic receptor activity
GO:0042043 0.00004 28.02710 2 8 9 neurexin family protein binding
GO:0019829 0.00005 2.77412 15 30 68 cation-transporting ATPase activity
GO:0022853 0.00005 2.77412 15 30 68 active ion transmembrane transporter activity
GO:0042625 0.00005 2.77412 15 30 68 ATPase coupled ion transmembrane transporter activity
GO:0016917 0.00005 5.26116 6 15 25 GABA receptor activity
GO:0042626 0.00006 2.15829 27 46 121 ATPase activity, coupled to transmembrane movement of substances
GO:0098772 0.00007 1.30660 263 317 1182 molecular function regulator
GO:0016229 0.00007 5.45500 5 14 23 steroid dehydrogenase activity
GO:0042277 0.00008 2.26891 23 40 102 peptide binding
GO:0015405 0.00009 2.09348 28 47 126 P-P-bond-hydrolysis-driven transmembrane transporter activity
GO:0015662 0.00009 3.94720 8 18 34 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
GO:0004890 0.00010 5.69746 5 13 21 GABA-A receptor activity
GO:0030276 0.00011 3.50941 9 20 40 clathrin binding
GO:0015399 0.00011 2.06715 28 47 127 primary active transmembrane transporter activity
GO:0048037 0.00012 1.47859 106 140 475 cofactor binding
GO:0004971 0.00012 Inf 1 6 6 AMPA glutamate receptor activity
GO:0015298 0.00013 3.97569 7 17 32 solute:cation antiporter activity
GO:0015078 0.00014 2.09140 26 44 118 proton transmembrane transporter activity
GO:0030159 0.00015 10.51134 3 9 12 receptor signaling complex scaffold activity
GO:0008509 0.00016 1.64115 61 87 274 anion transmembrane transporter activity
GO:0004952 0.00017 14.01251 2 8 10 dopamine neurotransmitter receptor activity
GO:0000155 0.00017 24.51732 2 7 8 phosphorelay sensor kinase activity
GO:0004673 0.00017 24.51732 2 7 8 protein histidine kinase activity
GO:0043492 0.00018 1.95484 31 50 140 ATPase activity, coupled to movement of substances
GO:0042805 0.00020 5.06403 5 13 22 actinin binding
GO:0051371 0.00020 5.06403 5 13 22 muscle alpha-actinin binding
GO:0051393 0.00020 5.06403 5 13 22 alpha-actinin binding
GO:0033764 0.00021 6.42551 4 11 17 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0015238 0.00023 2.45064 16 30 73 drug transmembrane transporter activity
GO:0051537 0.00025 4.46252 6 14 25 2 iron, 2 sulfur cluster binding
GO:0003779 0.00031 1.51111 82 110 367 actin binding
GO:0005319 0.00034 1.94909 29 46 129 lipid transporter activity
GO:1901618 0.00034 3.50744 8 17 34 organic hydroxy compound transmembrane transporter activity
GO:0000149 0.00037 2.21213 20 34 88 SNARE binding
GO:0005543 0.00040 1.60570 58 82 262 phospholipid binding
GO:0044325 0.00043 4.09034 6 14 26 ion channel binding
GO:0042803 0.00046 1.82932 34 52 152 protein homodimerization activity
GO:0016627 0.00047 2.69065 12 23 53 oxidoreductase activity, acting on the CH-CH group of donors
GO:0004683 0.00048 3.75685 6 15 29 calmodulin-dependent protein kinase activity
GO:0005343 0.00048 3.75685 6 15 29 organic acid:sodium symporter activity
GO:0000104 0.00054 Inf 1 5 5 succinate dehydrogenase activity
GO:0004985 0.00054 Inf 1 5 5 opioid receptor activity
GO:0005030 0.00054 Inf 1 5 5 neurotrophin receptor activity
GO:0008177 0.00054 Inf 1 5 5 succinate dehydrogenase (ubiquinone) activity
GO:0015280 0.00054 Inf 1 5 5 ligand-gated sodium channel activity
GO:0015125 0.00063 12.25775 2 7 9 bile acid transmembrane transporter activity
GO:0016775 0.00063 12.25775 2 7 9 phosphotransferase activity, nitrogenous group as acceptor
GO:0016769 0.00065 4.14268 5 13 24 transferase activity, transferring nitrogenous groups
GO:0005432 0.00068 21.00937 2 6 7 calcium:sodium antiporter activity
GO:0035240 0.00068 21.00937 2 6 7 dopamine binding
GO:1901338 0.00068 21.00937 2 6 7 catecholamine binding
GO:0043178 0.00069 2.66192 11 22 51 alcohol binding
GO:0035254 0.00087 6.30586 3 9 14 glutamate receptor binding
GO:0008483 0.00096 4.20563 5 12 22 transaminase activity
GO:0008519 0.00107 3.79718 6 13 25 ammonium transmembrane transporter activity
GO:0004129 0.00114 3.50548 6 14 28 cytochrome-c oxidase activity
GO:0015002 0.00114 3.50548 6 14 28 heme-copper terminal oxidase activity
GO:0016675 0.00114 3.50548 6 14 28 oxidoreductase activity, acting on a heme group of donors
GO:0016676 0.00114 3.50548 6 14 28 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GO:0008514 0.00118 1.68488 39 57 176 organic anion transmembrane transporter activity
GO:0005251 0.00119 5.00521 4 10 17 delayed rectifier potassium channel activity
GO:0071855 0.00119 5.00521 4 10 17 neuropeptide receptor binding
GO:0035255 0.00123 7.00521 3 8 12 ionotropic glutamate receptor binding
GO:0005342 0.00125 1.79656 30 46 136 organic acid transmembrane transporter activity
GO:0099516 0.00146 2.59821 10 20 47 ion antiporter activity
GO:0050662 0.00155 1.54410 55 75 246 coenzyme binding
GO:0046943 0.00165 1.77691 30 45 134 carboxylic acid transmembrane transporter activity
GO:0005000 0.00169 8.17123 2 7 10 vasopressin receptor activity
GO:0008307 0.00171 3.50483 6 13 26 structural constituent of muscle
GO:0005237 0.00175 5.25450 3 9 15 inhibitory extracellular ligand-gated ion channel activity
GO:0005391 0.00175 5.25450 3 9 15 sodium:potassium-exchanging ATPase activity
GO:0008331 0.00175 5.25450 3 9 15 high voltage-gated calcium channel activity
GO:0030215 0.00176 3.27154 6 14 29 semaphorin receptor binding
GO:0045499 0.00176 3.27154 6 14 29 chemorepellent activity
GO:0008081 0.00217 1.92554 21 34 96 phosphoric diester hydrolase activity
GO:0022840 0.00241 3.85416 5 11 21 leak channel activity
GO:0022841 0.00241 3.85416 5 11 21 potassium ion leak channel activity
GO:0022842 0.00241 3.85416 5 11 21 narrow pore channel activity
GO:0004937 0.00244 Inf 1 4 4 alpha1-adrenergic receptor activity
GO:0005219 0.00244 Inf 1 4 4 ryanodine-sensitive calcium-release channel activity
GO:0015277 0.00244 Inf 1 4 4 kainate selective glutamate receptor activity
GO:0016717 0.00244 Inf 1 4 4 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0048763 0.00244 Inf 1 4 4 calcium-induced calcium release activity
GO:0016791 0.00249 1.47146 63 84 285 phosphatase activity
GO:0015631 0.00257 1.56331 46 64 208 tubulin binding
GO:0000980 0.00257 5.60375 3 8 13 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0004983 0.00257 5.60375 3 8 13 neuropeptide Y receptor activity
GO:0005388 0.00257 5.60375 3 8 13 calcium-transporting ATPase activity
GO:0008373 0.00263 3.06684 7 14 30 sialyltransferase activity
GO:0001591 0.00265 17.50325 1 5 6 dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0016635 0.00265 17.50325 1 5 6 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
GO:0008028 0.00267 2.41866 11 20 49 monocarboxylic acid transmembrane transporter activity
GO:0015297 0.00271 2.24121 13 23 59 antiporter activity
GO:0005326 0.00297 2.26961 12 22 56 neurotransmitter transporter activity
GO:0008556 0.00322 4.50352 4 9 16 potassium-transporting ATPase activity
GO:0099095 0.00322 4.50352 4 9 16 ligand-gated anion channel activity
GO:0005416 0.00364 3.89236 4 10 19 amino acid:cation symporter activity
GO:0016247 0.00384 2.37934 10 19 47 channel regulator activity
GO:0038191 0.00387 3.50352 5 11 22 neuropilin binding
GO:0016709 0.00393 3.03706 6 13 28 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0070679 0.00483 4.66945 3 8 14 inositol 1,4,5 trisphosphate binding
GO:0032947 0.00490 2.14320 13 22 58 protein-containing complex scaffold activity
GO:0031994 0.00540 7.00208 2 6 9 insulin-like growth factor I binding
GO:0005283 0.00550 3.94029 4 9 17 amino acid:sodium symporter activity
GO:0004867 0.00566 1.99302 15 25 69 serine-type endopeptidase inhibitor activity
GO:0017046 0.00587 3.00313 6 12 26 peptide hormone binding
GO:0004089 0.00594 3.21132 5 11 23 carbonate dehydratase activity
GO:0015171 0.00626 1.94051 16 26 73 amino acid transmembrane transporter activity
GO:0001540 0.00727 4.90201 3 7 12 amyloid-beta binding
GO:0004966 0.00727 4.90201 3 7 12 galanin receptor activity
GO:0008266 0.00727 4.90201 3 7 12 poly(U) RNA binding
GO:0015347 0.00727 4.90201 3 7 12 sodium-independent organic anion transmembrane transporter activity
GO:0004303 0.00758 8.75098 2 5 7 estradiol 17-beta-dehydrogenase activity
GO:0008889 0.00758 8.75098 2 5 7 glycerophosphodiester phosphodiesterase activity
GO:0015467 0.00758 8.75098 2 5 7 G-protein activated inward rectifier potassium channel activity
GO:0042285 0.00758 8.75098 2 5 7 xylosyltransferase activity
GO:0008017 0.00800 1.52616 39 53 175 microtubule binding
GO:0030170 0.00841 2.14860 11 19 50 pyridoxal phosphate binding
GO:0070279 0.00841 2.14860 11 19 50 vitamin B6 binding
GO:0003954 0.00846 2.80271 6 12 27 NADH dehydrogenase activity
GO:0016655 0.00879 2.96408 5 11 24 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0005227 0.00895 3.18419 5 10 21 calcium activated cation channel activity
GO:0016616 0.00907 1.75426 21 31 93 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016829 0.01000 1.50946 38 52 173 lyase activity
GO:0003828 0.01005 13.99896 1 4 5 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0003876 0.01005 13.99896 1 4 5 AMP deaminase activity
GO:0004938 0.01005 13.99896 1 4 5 alpha2-adrenergic receptor activity
GO:0004995 0.01005 13.99896 1 4 5 tachykinin receptor activity
GO:0008121 0.01005 13.99896 1 4 5 ubiquinol-cytochrome-c reductase activity
GO:0016286 0.01005 13.99896 1 4 5 small conductance calcium-activated potassium channel activity
GO:0016534 0.01005 13.99896 1 4 5 cyclin-dependent protein kinase 5 activator activity
GO:0016681 0.01005 13.99896 1 4 5 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
GO:0030160 0.01005 13.99896 1 4 5 GKAP/Homer scaffold activity
GO:0047623 0.01005 13.99896 1 4 5 adenosine-phosphate deaminase activity
GO:0015269 0.01096 5.25117 2 6 10 calcium-activated potassium channel activity
GO:0016530 0.01096 5.25117 2 6 10 metallochaperone activity
GO:0031995 0.01096 5.25117 2 6 10 insulin-like growth factor II binding
GO:0047555 0.01096 5.25117 2 6 10 3',5'-cyclic-GMP phosphodiesterase activity
GO:0000035 0.01099 Inf 1 3 3 acyl binding
GO:0001588 0.01099 Inf 1 3 3 dopamine neurotransmitter receptor activity, coupled via Gs
GO:0003835 0.01099 Inf 1 3 3 beta-galactoside alpha-2,6-sialyltransferase activity
GO:0004556 0.01099 Inf 1 3 3 alpha-amylase activity
GO:0015018 0.01099 Inf 1 3 3 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
GO:0016160 0.01099 Inf 1 3 3 amylase activity
GO:0016215 0.01099 Inf 1 3 3 acyl-CoA desaturase activity
GO:0016519 0.01099 Inf 1 3 3 gastric inhibitory peptide receptor activity
GO:0031177 0.01099 Inf 1 3 3 phosphopantetheine binding
GO:0031841 0.01099 Inf 1 3 3 neuropeptide Y receptor binding
GO:0031843 0.01099 Inf 1 3 3 type 2 neuropeptide Y receptor binding
GO:0034040 0.01099 Inf 1 3 3 lipid-transporting ATPase activity
GO:0034041 0.01099 Inf 1 3 3 sterol-transporting ATPase activity
GO:0038046 0.01099 Inf 1 3 3 enkephalin receptor activity
GO:0044736 0.01099 Inf 1 3 3 acid-sensing ion channel activity
GO:0090599 0.01099 Inf 1 3 3 alpha-glucosidase activity
GO:0101006 0.01099 Inf 1 3 3 protein histidine phosphatase activity
GO:0016614 0.01126 1.70104 22 32 98 oxidoreductase activity, acting on CH-OH group of donors
GO:0005184 0.01259 2.75215 6 11 25 neuropeptide hormone activity
GO:0004312 0.01276 4.08470 3 7 13 fatty acid synthase activity
GO:0098632 0.01276 4.08470 3 7 13 cell-cell adhesion mediator activity
GO:0102336 0.01276 4.08470 3 7 13 3-oxo-arachidoyl-CoA synthase activity
GO:0102337 0.01276 4.08470 3 7 13 3-oxo-cerotoyl-CoA synthase activity
GO:0102338 0.01276 4.08470 3 7 13 3-oxo-lignoceronyl-CoA synthase activity
GO:0008137 0.01319 2.91862 5 10 22 NADH dehydrogenase (ubiquinone) activity
GO:0050136 0.01319 2.91862 5 10 22 NADH dehydrogenase (quinone) activity
GO:0015370 0.01339 1.78778 17 26 77 solute:sodium symporter activity
GO:0015355 0.01355 3.15176 4 9 19 secondary active monocarboxylate transmembrane transporter activity
GO:0045296 0.01363 2.33577 8 14 35 cadherin binding
GO:0051536 0.01452 1.88114 14 22 63 iron-sulfur cluster binding
GO:0051540 0.01452 1.88114 14 22 63 metal cluster binding
GO:0043177 0.01472 1.61577 25 35 111 organic acid binding
GO:0004857 0.01502 1.42406 46 60 208 enzyme inhibitor activity
GO:0015293 0.01604 1.56870 27 38 123 symporter activity
GO:0001664 0.01623 1.50434 33 45 150 G protein-coupled receptor binding
GO:0019888 0.01626 1.88750 13 21 60 protein phosphatase regulator activity
GO:0001517 0.01653 5.83355 2 5 8 N-acetylglucosamine 6-O-sulfotransferase activity
GO:0004977 0.01653 5.83355 2 5 8 melanocortin receptor activity
GO:0016531 0.01653 5.83355 2 5 8 copper chaperone activity
GO:0016594 0.01653 5.83355 2 5 8 glycine binding
GO:0030899 0.01653 5.83355 2 5 8 calcium-dependent ATPase activity
GO:0043121 0.01653 5.83355 2 5 8 neurotrophin binding
GO:0003924 0.01658 1.30716 80 97 358 GTPase activity
GO:0140104 0.01662 2.05425 10 17 46 molecular carrier activity
GO:0005254 0.01852 2.07639 10 16 43 chloride channel activity
GO:0019200 0.01877 2.69391 5 10 23 carbohydrate kinase activity
GO:0004931 0.01962 4.20062 2 6 11 extracellularly ATP-gated cation channel activity
GO:0005248 0.01962 4.20062 2 6 11 voltage-gated sodium channel activity
GO:0005313 0.01962 4.20062 2 6 11 L-glutamate transmembrane transporter activity
GO:0008253 0.01962 4.20062 2 6 11 5'-nucleotidase activity
GO:0008553 0.01962 4.20062 2 6 11 proton-exporting ATPase activity, phosphorylative mechanism
GO:0015172 0.01962 4.20062 2 6 11 acidic amino acid transmembrane transporter activity
GO:0015926 0.01962 4.20062 2 6 11 glucosidase activity
GO:0004114 0.01968 2.27695 7 13 33 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0015485 0.01968 2.27695 7 13 33 cholesterol binding
GO:0036442 0.01968 2.27695 7 13 33 proton-exporting ATPase activity
GO:0005344 0.01986 2.86502 4 9 20 oxygen carrier activity
GO:0015278 0.01986 2.86502 4 9 20 calcium-release channel activity
GO:0019825 0.01986 2.86502 4 9 20 oxygen binding
GO:0099604 0.01986 2.86502 4 9 20 ligand-gated calcium channel activity
GO:0046933 0.02060 3.11227 4 8 17 proton-transporting ATP synthase activity, rotational mechanism
GO:0051018 0.02060 3.11227 4 8 17 protein kinase A binding
GO:0003705 0.02062 2.10211 9 15 40 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005212 0.02069 3.50091 3 7 14 structural constituent of eye lens
GO:0008187 0.02069 3.50091 3 7 14 poly-pyrimidine tract binding
GO:0015101 0.02069 3.50091 3 7 14 organic cation transmembrane transporter activity
GO:0015556 0.02069 3.50091 3 7 14 C4-dicarboxylate transmembrane transporter activity
GO:0046875 0.02069 3.50091 3 7 14 ephrin receptor binding
GO:0098631 0.02069 3.50091 3 7 14 cell adhesion mediator activity
GO:0016818 0.02182 1.17769 203 228 911 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0015179 0.02296 2.13234 8 14 37 L-amino acid transmembrane transporter activity
GO:0015248 0.02296 2.13234 8 14 37 sterol transporter activity
GO:0019842 0.02357 1.58066 23 32 103 vitamin binding
GO:0000254 0.02483 6.99896 1 4 6 C-4 methylsterol oxidase activity
GO:0003854 0.02483 6.99896 1 4 6 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0003872 0.02483 6.99896 1 4 6 6-phosphofructokinase activity
GO:0004309 0.02483 6.99896 1 4 6 exopolyphosphatase activity
GO:0004731 0.02483 6.99896 1 4 6 purine-nucleoside phosphorylase activity
GO:0004999 0.02483 6.99896 1 4 6 vasoactive intestinal polypeptide receptor activity
GO:0015651 0.02483 6.99896 1 4 6 quaternary ammonium group transmembrane transporter activity
GO:0016679 0.02483 6.99896 1 4 6 oxidoreductase activity, acting on diphenols and related substances as donors
GO:0016933 0.02483 6.99896 1 4 6 extracellularly glycine-gated ion channel activity
GO:0016934 0.02483 6.99896 1 4 6 extracellularly glycine-gated chloride channel activity
GO:0017075 0.02483 6.99896 1 4 6 syntaxin-1 binding
GO:0042979 0.02483 6.99896 1 4 6 ornithine decarboxylase regulator activity
GO:0070095 0.02483 6.99896 1 4 6 fructose-6-phosphate binding
GO:0016817 0.02492 1.17227 203 228 914 hydrolase activity, acting on acid anhydrides
GO:0004864 0.02591 2.50130 5 10 24 protein phosphatase inhibitor activity
GO:0016462 0.02781 1.16852 202 226 908 pyrophosphatase activity
GO:0008195 0.02999 2.80083 4 8 18 phosphatidate phosphatase activity
GO:0031406 0.03011 1.55284 22 31 101 carboxylic acid binding
GO:0005324 0.03044 4.37484 2 5 9 long-chain fatty acid transporter activity
GO:0008503 0.03044 4.37484 2 5 9 benzodiazepine receptor activity
GO:0015168 0.03044 4.37484 2 5 9 glycerol transmembrane transporter activity
GO:0016208 0.03044 4.37484 2 5 9 AMP binding
GO:0022851 0.03044 4.37484 2 5 9 GABA-gated chloride ion channel activity
GO:0030507 0.03044 4.37484 2 5 9 spectrin binding
GO:0045309 0.03044 4.37484 2 5 9 protein phosphorylated amino acid binding
GO:0072349 0.03044 4.37484 2 5 9 modified amino acid transmembrane transporter activity
GO:0016298 0.03129 1.67940 16 23 71 lipase activity
GO:0005217 0.03145 2.26597 6 11 28 intracellular ligand-gated ion channel activity
GO:0005005 0.03147 3.06307 3 7 15 transmembrane-ephrin receptor activity
GO:0022821 0.03147 3.06307 3 7 15 potassium ion antiporter activity
GO:0031210 0.03147 3.06307 3 7 15 phosphatidylcholine binding
GO:0050997 0.03147 3.06307 3 7 15 quaternary ammonium group binding
GO:0140161 0.03147 3.06307 3 7 15 monocarboxylate:sodium symporter activity
GO:0001965 0.03196 3.50026 3 6 12 G-protein alpha-subunit binding
GO:0009922 0.03196 3.50026 3 6 12 fatty acid elongase activity
GO:0015279 0.03196 3.50026 3 6 12 store-operated calcium channel activity
GO:0032190 0.03196 3.50026 3 6 12 acrosin binding
GO:0035381 0.03196 3.50026 3 6 12 ATP-gated ion channel activity
GO:0004112 0.03257 2.06965 8 13 35 cyclic-nucleotide phosphodiesterase activity
GO:0005198 0.03296 1.21057 121 139 543 structural molecule activity
GO:0016597 0.03478 2.33438 6 10 25 amino acid binding
GO:0019212 0.03478 2.33438 6 10 25 phosphatase inhibitor activity
GO:0005200 0.03531 1.86834 10 16 46 structural constituent of cytoskeleton
GO:0005496 0.03585 1.75189 13 19 57 steroid binding
GO:0005310 0.03644 2.10125 7 12 32 dicarboxylic acid transmembrane transporter activity
GO:0001972 0.03664 10.49649 1 3 4 retinoic acid binding
GO:0003696 0.03664 10.49649 1 3 4 satellite DNA binding
GO:0003865 0.03664 10.49649 1 3 4 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0004069 0.03664 10.49649 1 3 4 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0004082 0.03664 10.49649 1 3 4 bisphosphoglycerate mutase activity
GO:0004104 0.03664 10.49649 1 3 4 cholinesterase activity
GO:0004619 0.03664 10.49649 1 3 4 phosphoglycerate mutase activity
GO:0004723 0.03664 10.49649 1 3 4 calcium-dependent protein serine/threonine phosphatase activity
GO:0004738 0.03664 10.49649 1 3 4 pyruvate dehydrogenase activity
GO:0004968 0.03664 10.49649 1 3 4 gonadotropin-releasing hormone receptor activity
GO:0008073 0.03664 10.49649 1 3 4 ornithine decarboxylase inhibitor activity
GO:0008184 0.03664 10.49649 1 3 4 glycogen phosphorylase activity
GO:0008332 0.03664 10.49649 1 3 4 low voltage-gated calcium channel activity
GO:0015187 0.03664 10.49649 1 3 4 glycine transmembrane transporter activity
GO:0033192 0.03664 10.49649 1 3 4 calmodulin-dependent protein phosphatase activity
GO:0033743 0.03664 10.49649 1 3 4 peptide-methionine (R)-S-oxide reductase activity
GO:0033765 0.03664 10.49649 1 3 4 steroid dehydrogenase activity, acting on the CH-CH group of donors
GO:0034338 0.03664 10.49649 1 3 4 short-chain carboxylesterase activity
GO:0035939 0.03664 10.49649 1 3 4 microsatellite binding
GO:0001077 0.03754 1.54035 21 29 95 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0030414 0.03781 1.43981 30 39 134 peptidase inhibitor activity
GO:0017111 0.03939 1.15814 192 214 865 nucleoside-triphosphatase activity
GO:0005160 0.03977 1.87647 10 15 43 transforming growth factor beta receptor binding
GO:0033293 0.04077 2.13992 6 11 29 monocarboxylic acid binding
GO:0050839 0.04107 1.55144 20 27 88 cell adhesion molecule binding
GO:0005253 0.04253 1.70685 13 19 58 anion channel activity
GO:0004435 0.04546 2.72253 4 7 16 phosphatidylinositol phospholipase C activity
GO:0004629 0.04546 2.72253 4 7 16 phospholipase C activity
GO:0005003 0.04546 2.72253 4 7 16 ephrin receptor activity
GO:0005523 0.04546 2.72253 4 7 16 tropomyosin binding
GO:0030246 0.04616 1.33780 43 53 192 carbohydrate binding
GO:0019208 0.04620 1.63510 15 21 66 phosphatase regulator activity
GO:0001784 0.04782 4.66563 2 4 7 phosphotyrosine residue binding
GO:0008273 0.04782 4.66563 2 4 7 calcium, potassium:sodium antiporter activity
GO:0008502 0.04782 4.66563 2 4 7 melatonin receptor activity
GO:0032051 0.04782 4.66563 2 4 7 clathrin light chain binding
GO:0043176 0.04782 4.66563 2 4 7 amine binding
GO:0051378 0.04782 4.66563 2 4 7 serotonin binding
GO:0005452 0.04842 3.00000 3 6 13 inorganic anion exchanger activity
GO:0008252 0.04842 3.00000 3 6 13 nucleotidase activity
GO:0008443 0.04842 3.00000 3 6 13 phosphofructokinase activity
GO:0016846 0.04842 3.00000 3 6 13 carbon-sulfur lyase activity
GO:0042577 0.04842 3.00000 3 6 13 lipid phosphatase activity
GO:0000036 0.04945 Inf 0 2 2 acyl carrier activity
GO:0000268 0.04945 Inf 0 2 2 peroxisome targeting sequence binding
GO:0001616 0.04945 Inf 0 2 2 growth hormone secretagogue receptor activity
GO:0001665 0.04945 Inf 0 2 2 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
GO:0004053 0.04945 Inf 0 2 2 arginase activity
GO:0004084 0.04945 Inf 0 2 2 branched-chain-amino-acid transaminase activity
GO:0004133 0.04945 Inf 0 2 2 glycogen debranching enzyme activity
GO:0004134 0.04945 Inf 0 2 2 4-alpha-glucanotransferase activity
GO:0004135 0.04945 Inf 0 2 2 amylo-alpha-1,6-glucosidase activity
GO:0004351 0.04945 Inf 0 2 2 glutamate decarboxylase activity
GO:0004365 0.04945 Inf 0 2 2 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0004373 0.04945 Inf 0 2 2 glycogen (starch) synthase activity
GO:0004419 0.04945 Inf 0 2 2 hydroxymethylglutaryl-CoA lyase activity
GO:0004705 0.04945 Inf 0 2 2 JUN kinase activity
GO:0004768 0.04945 Inf 0 2 2 stearoyl-CoA 9-desaturase activity
GO:0004807 0.04945 Inf 0 2 2 triose-phosphate isomerase activity
GO:0004990 0.04945 Inf 0 2 2 oxytocin receptor activity
GO:0005052 0.04945 Inf 0 2 2 peroxisome matrix targeting signal-1 binding
GO:0005250 0.04945 Inf 0 2 2 A-type (transient outward) potassium channel activity
GO:0005252 0.04945 Inf 0 2 2 open rectifier potassium channel activity
GO:0008454 0.04945 Inf 0 2 2 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
GO:0008478 0.04945 Inf 0 2 2 pyridoxal kinase activity
GO:0015275 0.04945 Inf 0 2 2 stretch-activated, cation-selective, calcium channel activity
GO:0016521 0.04945 Inf 0 2 2 pituitary adenylate cyclase activating polypeptide activity
GO:0016595 0.04945 Inf 0 2 2 glutamate binding
GO:0016909 0.04945 Inf 0 2 2 SAP kinase activity
GO:0031628 0.04945 Inf 0 2 2 opioid receptor binding
GO:0031769 0.04945 Inf 0 2 2 glucagon receptor binding
GO:0031821 0.04945 Inf 0 2 2 G protein-coupled serotonin receptor binding
GO:0031858 0.04945 Inf 0 2 2 pituitary adenylate cyclase-activating polypeptide receptor binding
GO:0032795 0.04945 Inf 0 2 2 heterotrimeric G-protein binding
GO:0032896 0.04945 Inf 0 2 2 palmitoyl-CoA 9-desaturase activity
GO:0034618 0.04945 Inf 0 2 2 arginine binding
GO:0035379 0.04945 Inf 0 2 2 carbon dioxide transmembrane transporter activity
GO:0038047 0.04945 Inf 0 2 2 morphine receptor activity
GO:0043891 0.04945 Inf 0 2 2 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity
GO:0044620 0.04945 Inf 0 2 2 ACP phosphopantetheine attachment site binding
GO:0044715 0.04945 Inf 0 2 2 8-oxo-dGDP phosphatase activity
GO:0045545 0.04945 Inf 0 2 2 syndecan binding
GO:0047750 0.04945 Inf 0 2 2 cholestenol delta-isomerase activity
GO:0051192 0.04945 Inf 0 2 2 prosthetic group binding
GO:0052654 0.04945 Inf 0 2 2 L-leucine transaminase activity
GO:0052655 0.04945 Inf 0 2 2 L-valine transaminase activity
GO:0052656 0.04945 Inf 0 2 2 L-isoleucine transaminase activity
GO:0061598 0.04945 Inf 0 2 2 molybdopterin adenylyltransferase activity
GO:0061599 0.04945 Inf 0 2 2 molybdopterin molybdotransferase activity
GO:0070735 0.04945 Inf 0 2 2 protein-glycine ligase activity
GO:0070738 0.04945 Inf 0 2 2 tubulin-glycine ligase activity
GO:0097718 0.04945 Inf 0 2 2 disordered domain specific binding
GO:0099530 0.04945 Inf 0 2 2 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential
GO:0099583 0.04945 Inf 0 2 2 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
GO:0140135 0.04945 Inf 0 2 2 mechanosensitive cation channel activity
GO:0015166 0.04992 3.49961 2 5 10 polyol transmembrane transporter activity
GO:0015271 0.04992 3.49961 2 5 10 outward rectifier potassium channel activity
GO:0019894 0.04992 3.49961 2 5 10 kinesin binding
GO:0051219 0.04992 3.49961 2 5 10 phosphoprotein binding
GO:0051428 0.04992 3.49961 2 5 10 peptide hormone receptor binding