TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols R-MMU-5689880 Ub-specific processing proteases 0.90245377702979 -0.102637806674205 171 16 0.0150659133709981 1062 8688 107995,66313,17125,67952,59040,17246,69641,14462,26440,27401,235323,21951,15251,67561,22258,11555 Cdc20,Smurf2,Smad1,Tomm20,Rhot1,Mdm2,Wdr20,Gata3,Psma1,Skp2,Usp28,Tnks,Hif1a,Wdr48,Usp4,Adrb2 R-MMU-163210 Formation of ATP by chemiosmotic coupling 0.904562472267936 -0.1003039082423 18 1 0.000941619585687382 1062 8688 28080 Atp5o R-MMU-5674135 MAP2K and MAPK activation 0.904562472267936 -0.1003039082423 18 1 0.000941619585687382 1062 8688 16706 Ksr1 R-MMU-210745 Regulation of gene expression in beta cells 0.904562472267936 -0.1003039082423 18 1 0.000941619585687382 1062 8688 15376 Foxa2 R-MMU-8854214 TBC/RABGAPs 0.906995374426491 -0.0976179287405444 31 2 0.00188323917137476 1062 8688 71648,67443 Optn,Map1lc3b R-MMU-68882 Mitotic Anaphase 0.907060916167737 -0.0975456688645805 172 16 0.0150659133709981 1062 8688 83431,73699,16905,107995,22367,26440,226849,12237,56317,216080,226747,26931,56430,22194,12617,17120 Ndel1,Ppp2r1b,Lmna,Cdc20,Vrk1,Psma1,Ppp2r5a,Bub3,Anapc7,Ube2d1,Ahctf1,Ppp2r5c,Clip1,Ube2e1,Cenpc1,Mad1l1 R-MMU-72649 Translation initiation complex formation 0.910256690349732 -0.0940286419401669 54 4 0.00376647834274953 1062 8688 20044,68135,14109,267019 Rps14,Eif3h,Fau,Rps15a R-MMU-212300 PRC2 methylates histones and DNA 0.910512915654516 -0.0937471946822268 43 3 0.00282485875706215 1062 8688 13435,13433,11569 Dnmt3a,Dnmt1,Aebp2 R-MMU-72312 rRNA processing 0.910786738574071 -0.0934465050939075 125 11 0.0103578154425612 1062 8688 213895,20044,68979,14791,56040,19946,50912,66446,216987,57316,76130 Bms1,Rps14,Nol11,Emg1,Rplp1,Rpl30,Exosc10,Exosc7,Utp6,C1d,Las1l R-MMU-8868773 rRNA processing in the nucleus and cytosol 0.910786738574071 -0.0934465050939075 125 11 0.0103578154425612 1062 8688 213895,20044,68979,56040,14791,19946,50912,66446,216987,76130,57316 Bms1,Rps14,Nol11,Rplp1,Emg1,Rpl30,Exosc10,Exosc7,Utp6,Las1l,C1d R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 0.910786738574071 -0.0934465050939075 125 11 0.0103578154425612 1062 8688 66446,216987,76130,57316,19946,50912,20044,68979,56040,14791,213895 Exosc7,Utp6,Las1l,C1d,Rpl30,Exosc10,Rps14,Nol11,Rplp1,Emg1,Bms1 R-MMU-2555396 Mitotic Metaphase and Anaphase 0.911488278563886 -0.0926765444481485 173 16 0.0150659133709981 1062 8688 16905,107995,22367,83431,73699,226849,12237,56317,26440,216080,226747,26931,56430,12617,22194,17120 Lmna,Cdc20,Vrk1,Ndel1,Ppp2r1b,Ppp2r5a,Bub3,Anapc7,Psma1,Ube2d1,Ahctf1,Ppp2r5c,Clip1,Cenpc1,Ube2e1,Mad1l1 R-MMU-912446 Meiotic recombination 0.916252743837028 -0.0874630311478027 19 1 0.000941619585687382 1062 8688 12144 Blm R-MMU-5620916 VxPx cargo-targeting to cilium 0.916252743837028 -0.0874630311478027 19 1 0.000941619585687382 1062 8688 13196 Asap1 R-MMU-77595 Processing of Intronless Pre-mRNAs 0.916252743837028 -0.0874630311478027 19 1 0.000941619585687382 1062 8688 228410 Cstf3 R-MMU-73933 Resolution of Abasic Sites (AP sites) 0.916257074775392 -0.0874583043645469 32 2 0.00188323917137476 1062 8688 16881,67967 Lig1,Pold3 R-MMU-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 0.917413628694107 -0.0861968411477382 55 4 0.00376647834274953 1062 8688 267019,68135,14109,20044 Rps15a,Eif3h,Fau,Rps14 R-MMU-72165 mRNA Splicing - Minor Pathway 0.917413628694107 -0.0861968411477382 55 4 0.00376647834274953 1062 8688 107686,67225,22184,67178 Snrpd2,Rnpc3,Zrsr2,Zmat5 R-MMU-72702 Ribosomal scanning and start codon recognition 0.917413628694107 -0.0861968411477382 55 4 0.00376647834274953 1062 8688 20044,68135,267019,14109 Rps14,Eif3h,Rps15a,Fau R-MMU-174154 APC/C:Cdc20 mediated degradation of Securin 0.919017096663437 -0.0844505532484203 66 5 0.00470809792843691 1062 8688 107995,56317,216080,22194,26440 Cdc20,Anapc7,Ube2d1,Ube2e1,Psma1 R-MMU-199977 ER to Golgi Anterograde Transport 0.924333284056983 -0.0786825753446224 118 10 0.00941619585687382 1062 8688 78232,20742,11735,20741,70361,13191,69608,72978,13426,77038 Trappc6b,Sptbn1,Ank3,Sptb,Lman1,Dctn1,Sec24d,Cnih3,Dync1i1,Arfgap2 R-MMU-6783310 Fanconi Anemia Pathway 0.924646780337725 -0.0783434734908124 33 2 0.00188323917137476 1062 8688 14088,67196 Fancc,Ube2t R-MMU-73884 Base Excision Repair 0.924646780337725 -0.0783434734908124 33 2 0.00188323917137476 1062 8688 67967,16881 Pold3,Lig1 R-MMU-983169 Class I MHC mediated antigen processing & presentation 0.927990743837329 -0.0747335205589038 215 20 0.0188323917137476 1062 8688 83814,218215,231670,26440,30838,224826,67731,66313,380928,244421,22019,27401,74244,16419,50760,12234,269514,17970,69608,218203 Nedd4l,Rnf144b,Fbxo21,Psma1,Fbxw4,Ubr2,Fbxo32,Smurf2,Lmo7,Lonrf1,Tpp2,Skp2,Atg7,Itgb5,Fbxo17,Btrc,Fbxl4,Ncf2,Sec24d,Mylip R-MMU-3371453 Regulation of HSF1-mediated heat shock response 0.930213673861723 -0.0723409623843341 57 4 0.00376647834274953 1062 8688 218210,15481,107939,71805 Nup153,Hspa8,Pom121,Nup93 R-MMU-2559582 Senescence-Associated Secretory Phenotype (SASP) 0.930716053662052 -0.0718010389201607 68 5 0.00470809792843691 1062 8688 22194,20111,216080,56317,12571 Ube2e1,Rps6ka1,Ube2d1,Anapc7,Cdk6 R-MMU-75953 RNA Polymerase II Transcription Initiation 0.932218178524989 -0.0701883945631866 46 3 0.00282485875706215 1062 8688 72504,83602,228980 Taf4b,Gtf2a1,Taf4 R-MMU-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 0.932218178524989 -0.0701883945631866 46 3 0.00282485875706215 1062 8688 228980,83602,72504 Taf4,Gtf2a1,Taf4b R-MMU-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 0.932218178524989 -0.0701883945631866 46 3 0.00282485875706215 1062 8688 228980,83602,72504 Taf4,Gtf2a1,Taf4b R-MMU-73776 RNA Polymerase II Promoter Escape 0.932218178524989 -0.0701883945631866 46 3 0.00282485875706215 1062 8688 228980,72504,83602 Taf4,Taf4b,Gtf2a1 R-MMU-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation 0.932239045806154 -0.0701660102672177 34 2 0.00188323917137476 1062 8688 330817,271970 Dhps,Arsj R-MMU-156584 Cytosolic sulfonation of small molecules 0.935515933276053 -0.0666571015840072 21 1 0.000941619585687382 1062 8688 23972 Papss2 R-MMU-72172 mRNA Splicing 0.937835704628507 -0.0641805002976075 180 16 0.0150659133709981 1062 8688 67285,67178,22184,68981,74326,76522,228410,76938,15481,67225,15388,71702,229279,67678,78651,107686 Cwc27,Zmat5,Zrsr2,Snrpa1,Hnrnpr,Lsm8,Cstf3,Rbm17,Hspa8,Rnpc3,Hnrnpl,Cdc5l,Hnrnpa3,Lsm3,Lsm6,Snrpd2 R-MMU-196849 Metabolism of water-soluble vitamins and cofactors 0.941244627020882 -0.0605522082286744 112 9 0.00847457627118644 1062 8688 226518,23959,18113,59027,93835,116914,67993,20525,14276 Nmnat2,Nt5e,Nnmt,Nampt,Amn,Slc19a2,Nudt12,Slc2a1,Folr2 R-MMU-1592230 Mitochondrial biogenesis 0.943417407699567 -0.0582464562144804 22 1 0.000941619585687382 1062 8688 108099 Prkag2 R-MMU-1679131 Trafficking and processing of endosomal TLR 0.943417407699567 -0.0582464562144804 22 1 0.000941619585687382 1062 8688 218275 BC051665 R-MMU-2262752 Cellular responses to stress 0.944463564850884 -0.0571381689086482 360 35 0.0329566854990584 1062 8688 216080,26399,74244,23872,26408,108099,20111,16906,22194,26419,20655,67443,67605,216850,26420,105787,11927,15481,68576,23871,26440,13819,17970,68942,15251,12571,218210,78610,17246,107939,54383,56317,12323,71805,14782 Ube2d1,Map2k6,Atg7,Ets2,Map3k5,Prkag2,Rps6ka1,Lmnb1,Ube2e1,Mapk8,Sod1,Map1lc3b,Akt1s1,Kdm6b,Mapk9,Prkaa1,Atox1,Hspa8,Lamtor5,Ets1,Psma1,Epas1,Ncf2,Chmp2b,Hif1a,Cdk6,Nup153,Uvrag,Mdm2,Pom121,Phc2,Anapc7,Camk2b,Nup93,Gsr R-MMU-72202 Transport of Mature Transcript to Cytoplasm 0.945445448757808 -0.0560990882034955 71 5 0.00470809792843691 1062 8688 218210,73826,66231,71805,107939 Nup153,Poldip3,Thoc7,Nup93,Pom121 R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 0.945445448757808 -0.0560990882034955 71 5 0.00470809792843691 1062 8688 107939,71805,73826,66231,218210 Pom121,Nup93,Poldip3,Thoc7,Nup153 R-MMU-72203 Processing of Capped Intron-Containing Pre-mRNA 0.947147401939322 -0.0543005464414145 231 21 0.019774011299435 1062 8688 22184,67178,67285,107939,218210,66231,71805,68981,74326,15481,76938,228410,76522,71702,67225,15388,229279,78651,67678,107686,73826 Zrsr2,Zmat5,Cwc27,Pom121,Nup153,Thoc7,Nup93,Snrpa1,Hnrnpr,Hspa8,Rbm17,Cstf3,Lsm8,Cdc5l,Rnpc3,Hnrnpl,Hnrnpa3,Lsm6,Lsm3,Snrpd2,Poldip3 R-MMU-504046 RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription 0.948462723114619 -0.0529127912601066 114 9 0.00847457627118644 1062 8688 78929,67486,75627,66596,17191,70239,70428,18519,269252 Polr3h,Polr3g,Snapc1,Gtf3a,Mbd2,Gtf3c5,Polr3b,Kat2b,Gtf3c4 R-MMU-5654738 Signaling by FGFR2 0.949687035784658 -0.0516227846796646 72 5 0.00470809792843691 1062 8688 14172,20779,93686,14164,18706 Fgf18,Src,Rbfox2,Fgf1,Pik3ca R-MMU-5389840 Mitochondrial translation elongation 0.950094973824503 -0.0511933269376169 83 6 0.00564971751412429 1062 8688 232536,59054,52443,56280,64657,68565 Mrps35,Mrps30,Mrpl48,Mrpl37,Mrps10,Mrps18a R-MMU-70895 Branched-chain amino acid catabolism 0.95035148491481 -0.0509233786939455 23 1 0.000941619585687382 1062 8688 12040 Bckdhb R-MMU-933541 TRAF6 mediated IRF7 activation 0.95035148491481 -0.0509233786939455 23 1 0.000941619585687382 1062 8688 72162 Dhx36 R-MMU-176187 Activation of ATR in response to replication stress 0.950900023897279 -0.0503463493055169 37 2 0.00188323917137476 1062 8688 17219,12545 Mcm6,Cdc7 R-MMU-196071 Metabolism of steroid hormones 0.950900023897279 -0.0503463493055169 37 2 0.00188323917137476 1062 8688 15487,15484 Hsd17b3,Hsd11b2 R-MMU-69275 G2/M Transition 0.951156234418248 -0.0500769455784725 165 14 0.0131826741996234 1062 8688 259279,73699,12234,268930,13191,381644,73738,22390,26440,71648,22628,83922,18005,19088 Tubgcp3,Ppp2r1b,Btrc,Pkmyt1,Dctn1,Cep135,Haus7,Wee1,Psma1,Optn,Ywhag,Cep41,Nek2,Prkar2b R-MMU-2467813 Separation of Sister Chromatids 0.953848800951794 -0.0472501096629998 166 14 0.0131826741996234 1062 8688 73699,83431,107995,216080,226747,17120,26440,12617,22194,56430,26931,56317,12237,226849 Ppp2r1b,Ndel1,Cdc20,Ube2d1,Ahctf1,Mad1l1,Psma1,Cenpc1,Ube2e1,Clip1,Ppp2r5c,Anapc7,Bub3,Ppp2r5a R-MMU-204005 COPII (Coat Protein 2) Mediated Vesicle Transport 0.954734091673414 -0.0463224153107845 62 4 0.00376647834274953 1062 8688 69608,72978,78232,70361 Sec24d,Cnih3,Trappc6b,Lman1 R-MMU-174084 Autodegradation of Cdh1 by Cdh1:APC/C 0.954734091673414 -0.0463224153107845 62 4 0.00376647834274953 1062 8688 216080,56317,22194,26440 Ube2d1,Anapc7,Ube2e1,Psma1 R-MMU-453274 Mitotic G2-G2/M phases 0.956410892635135 -0.0445676542583744 167 14 0.0131826741996234 1062 8688 73699,259279,12234,268930,381644,13191,73738,22390,26440,71648,83922,22628,18005,19088 Ppp2r1b,Tubgcp3,Btrc,Pkmyt1,Cep135,Dctn1,Haus7,Wee1,Psma1,Optn,Cep41,Ywhag,Nek2,Prkar2b R-MMU-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism 0.956436507771113 -0.0445408720529845 24 1 0.000941619585687382 1062 8688 93835 Amn R-MMU-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 0.956436507771113 -0.0445408720529845 24 1 0.000941619585687382 1062 8688 97064 Wwtr1 R-MMU-5419276 Mitochondrial translation termination 0.957220286430013 -0.0437217296601571 85 6 0.00564971751412429 1062 8688 232536,59054,64657,68565,56280,52443 Mrps35,Mrps30,Mrps10,Mrps18a,Mrpl37,Mrpl48 R-MMU-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 0.957284259378724 -0.0436548998906746 74 5 0.00470809792843691 1062 8688 67967,227195,108679,225280,70620 Pold3,Ino80d,Cops8,Ino80c,Ube2v2 R-MMU-5687128 MAPK6/MAPK4 signaling 0.957284259378724 -0.0436548998906746 74 5 0.00470809792843691 1062 8688 17979,260409,26440,224105,18479 Ncoa3,Cdc42ep3,Psma1,Pak2,Pak1 R-MMU-3214842 HDMs demethylate histones 0.957913494552927 -0.0429978030498371 51 3 0.00282485875706215 1062 8688 99982,216850,18676 Kdm1a,Kdm6b,Phf2 R-MMU-5368287 Mitochondrial translation 0.960425495758462 -0.0403788679669319 86 6 0.00564971751412429 1062 8688 232536,59054,52443,56280,64657,68565 Mrps35,Mrps30,Mrpl48,Mrpl37,Mrps10,Mrps18a R-MMU-166658 Complement cascade 0.960495207198616 -0.0403062866885091 39 2 0.00188323917137476 1062 8688 110382,17221 C8b,Cd46 R-MMU-68886 M Phase 0.961373812696284 -0.0393919626114971 247 22 0.0207156308851224 1062 8688 226747,59021,216080,18750,17120,56430,12617,26931,22194,107995,22367,218210,16905,73699,107939,71175,83431,56317,226849,12237,26440,71805 Ahctf1,Rab2a,Ube2d1,Prkca,Mad1l1,Clip1,Cenpc1,Ppp2r5c,Ube2e1,Cdc20,Vrk1,Nup153,Lmna,Ppp2r1b,Pom121,Nipbl,Ndel1,Anapc7,Ppp2r5a,Bub3,Psma1,Nup93 R-MMU-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 0.961776354121795 -0.0389733354669981 25 1 0.000941619585687382 1062 8688 68942 Chmp2b R-MMU-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 0.961809948440458 -0.0389384066274422 52 3 0.00282485875706215 1062 8688 26419,70620,14048 Mapk8,Ube2v2,Eya1 R-MMU-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 0.962097348841503 -0.0386396392142843 64 4 0.00376647834274953 1062 8688 216080,15251,13819,26440 Ube2d1,Hif1a,Epas1,Psma1 R-MMU-1852241 Organelle biogenesis and maintenance 0.962159671203372 -0.0385748637074342 276 25 0.0235404896421846 1062 8688 19088,238799,83922,231214,72938,319845,59054,73738,260305,52443,382090,381644,217935,13196,18005,108099,22628,68565,64657,232536,67068,56280,73916,13191,76260 Prkar2b,Tnpo1,Cep41,Cc2d2a,Hspb11,Bbs9,Mrps30,Haus7,Nphp4,Mrpl48,Cep162,Cep135,Wdr60,Asap1,Nek2,Prkag2,Ywhag,Mrps18a,Mrps10,Mrps35,Dynlrb1,Mrpl37,Ift57,Dctn1,Ttc8 R-MMU-1169091 Activation of NF-kappaB in B cells 0.965347166878628 -0.0352674839172477 65 4 0.00376647834274953 1062 8688 12234,26440,240354,16150 Btrc,Psma1,Malt1,Ikbkb R-MMU-5693606 DNA Double Strand Break Response 0.965365340823629 -0.035248657763764 53 3 0.00282485875706215 1062 8688 14048,70620,26419 Eya1,Ube2v2,Mapk8 R-MMU-4839726 Chromatin organization 0.965699909855702 -0.0349021453553377 191 16 0.0150659133709981 1062 8688 228829,18600,18676,319177,11569,99982,13435,28019,69726,140858,225888,17978,239985,231051,14013,216850 Phf20,Padi2,Phf2,Hist1h2ba,Aebp2,Kdm1a,Dnmt3a,Ing4,Smyd3,Wdr5,Kmt5b,Ncoa2,Arid1b,Kmt2c,Mecom,Kdm6b R-MMU-3247509 Chromatin modifying enzymes 0.965699909855702 -0.0349021453553377 191 16 0.0150659133709981 1062 8688 18676,18600,228829,99982,13435,11569,319177,140858,28019,69726,216850,231051,14013,239985,225888,17978 Phf2,Padi2,Phf20,Kdm1a,Dnmt3a,Aebp2,Hist1h2ba,Wdr5,Ing4,Smyd3,Kdm6b,Kmt2c,Mecom,Arid1b,Kmt5b,Ncoa2 R-MMU-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 0.966189242305808 -0.0343955609480243 88 6 0.00564971751412429 1062 8688 14109,267019,19946,225363,56040,20044 Fau,Rps15a,Rpl30,Etf1,Rplp1,Rps14 R-MMU-110314 Recognition of DNA damage by PCNA-containing replication complex 0.966462203363978 -0.0341130878092737 26 1 0.000941619585687382 1062 8688 67967 Pold3 R-MMU-3214847 HATs acetylate histones 0.966729499219104 -0.0338365545958605 77 5 0.00470809792843691 1062 8688 140858,319177,28019,17978,228829 Wdr5,Hist1h2ba,Ing4,Ncoa2,Phf20 R-MMU-69278 Cell Cycle, Mitotic 0.967529760631104 -0.033009094209063 438 42 0.0395480225988701 1062 8688 12234,17219,27401,59021,226747,216080,18750,17120,22390,22194,26931,381644,83431,71175,272551,73738,16881,26440,83922,226849,13191,12617,19076,56430,18005,22628,107939,259279,73699,268930,107995,12545,22367,218210,16905,12571,67967,71805,56317,71648,12237,19088 Btrc,Mcm6,Skp2,Rab2a,Ahctf1,Ube2d1,Prkca,Mad1l1,Wee1,Ube2e1,Ppp2r5c,Cep135,Ndel1,Nipbl,Gins2,Haus7,Lig1,Psma1,Cep41,Ppp2r5a,Dctn1,Cenpc1,Prim2,Clip1,Nek2,Ywhag,Pom121,Tubgcp3,Ppp2r1b,Pkmyt1,Cdc20,Cdc7,Vrk1,Nup153,Lmna,Cdk6,Pold3,Nup93,Anapc7,Optn,Bub3,Prkar2b R-MMU-4641257 Degradation of AXIN 0.968607026143406 -0.031896295122937 54 3 0.00282485875706215 1062 8688 21951,26440,66313 Tnks,Psma1,Smurf2 R-MMU-174113 SCF-beta-TrCP mediated degradation of Emi1 0.968607026143406 -0.031896295122937 54 3 0.00282485875706215 1062 8688 26440,12234,107995 Psma1,Btrc,Cdc20 R-MMU-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 0.970574087449319 -0.0298675398232891 27 1 0.000941619585687382 1062 8688 242851 Gnat3 R-MMU-5656169 Termination of translesion DNA synthesis 0.970574087449319 -0.0298675398232891 27 1 0.000941619585687382 1062 8688 67967 Pold3 R-MMU-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) 0.970574087449319 -0.0298675398232891 27 1 0.000941619585687382 1062 8688 230639 Cyp4a29 R-MMU-1266695 Interleukin-7 signaling 0.970574087449319 -0.0298675398232891 27 1 0.000941619585687382 1062 8688 16451 Jak1 R-MMU-5357905 Regulation of TNFR1 signaling 0.970574087449319 -0.0298675398232891 27 1 0.000941619585687382 1062 8688 16150 Ikbkb R-MMU-73886 Chromosome Maintenance 0.97108332693434 -0.0293429987864151 67 4 0.00376647834274953 1062 8688 67967,16881,19076,12617 Pold3,Lig1,Prim2,Cenpc1 R-MMU-72187 mRNA 3'-end processing 0.971560491388567 -0.0288517461344128 55 3 0.00282485875706215 1062 8688 66231,73826,228410 Thoc7,Poldip3,Cstf3 R-MMU-391251 Protein folding 0.974182252694017 -0.0261568750882809 28 1 0.000941619585687382 1062 8688 242851 Gnat3 R-MMU-6803529 FGFR2 alternative splicing 0.974182252694017 -0.0261568750882809 28 1 0.000941619585687382 1062 8688 93686 Rbfox2 R-MMU-75067 Processing of Capped Intronless Pre-mRNA 0.974182252694017 -0.0261568750882809 28 1 0.000941619585687382 1062 8688 228410 Cstf3 R-MMU-390466 Chaperonin-mediated protein folding 0.974182252694017 -0.0261568750882809 28 1 0.000941619585687382 1062 8688 242851 Gnat3 R-MMU-6788656 Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism 0.974571326462243 -0.0257575698322894 43 2 0.00188323917137476 1062 8688 15109,78920 Hal,Dlst R-MMU-1234174 Regulation of Hypoxia-inducible Factor (HIF) by oxygen 0.975921726123708 -0.0243728944288693 69 4 0.00376647834274953 1062 8688 216080,15251,13819,26440 Ube2d1,Hif1a,Epas1,Psma1 R-MMU-2262749 Cellular response to hypoxia 0.975921726123708 -0.0243728944288693 69 4 0.00376647834274953 1062 8688 15251,216080,26440,13819 Hif1a,Ube2d1,Psma1,Epas1 R-MMU-5610780 Degradation of GLI1 by the proteasome 0.97669586975784 -0.023579965310208 57 3 0.00282485875706215 1062 8688 18222,12234,26440 Numb,Btrc,Psma1 R-MMU-5693567 HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) 0.977059710815022 -0.0232075123124983 104 7 0.00659133709981168 1062 8688 70620,19363,67967,223970,57434,12144,225182 Ube2v2,Rad51b,Pold3,Rmi2,Xrcc2,Blm,Rbbp8 R-MMU-69481 G2/M Checkpoints 0.977237772356047 -0.0230252866861019 147 11 0.0103578154425612 1062 8688 22628,22390,12144,223970,225182,26440,70620,17219,12545,268930,22630 Ywhag,Wee1,Blm,Rmi2,Rbbp8,Psma1,Ube2v2,Mcm6,Cdc7,Pkmyt1,Ywhaq R-MMU-69306 DNA Replication 0.980383799217204 -0.0198111521309683 106 7 0.00659133709981168 1062 8688 272551,12545,17219,26440,19076,67967,16881 Gins2,Cdc7,Mcm6,Psma1,Prim2,Pold3,Lig1 R-MMU-72689 Formation of a pool of free 40S subunits 0.980825885762057 -0.0193603216504466 95 6 0.00564971751412429 1062 8688 56040,20044,19946,14109,68135,267019 Rplp1,Rps14,Rpl30,Fau,Eif3h,Rps15a R-MMU-5610785 GLI3 is processed to GLI3R by the proteasome 0.980941226790906 -0.0192427327396694 59 3 0.00282485875706215 1062 8688 26440,12234,14634 Psma1,Btrc,Gli3 R-MMU-72163 mRNA Splicing - Major Pathway 0.981555789171128 -0.0186164261564621 171 13 0.012241054613936 1062 8688 76522,67678,228410,107686,78651,76938,15481,74326,68981,229279,71702,15388,67285 Lsm8,Lsm3,Cstf3,Snrpd2,Lsm6,Rbm17,Hspa8,Hnrnpr,Snrpa1,Hnrnpa3,Cdc5l,Hnrnpl,Cwc27 R-MMU-6807505 RNA polymerase II transcribes snRNA genes 0.981774148836991 -0.0183939880806846 72 4 0.00376647834274953 1062 8688 13716,83602,192657,75627 Ell,Gtf2a1,Ell2,Snapc1 R-MMU-382556 ABC-family proteins mediated transport 0.982352749526929 -0.0178048197258739 96 6 0.00564971751412429 1062 8688 11806,11304,239273,26440,12780,74591 Apoa1,Abca4,Abcc4,Psma1,Abcc2,Abca12 R-MMU-6803157 Antimicrobial peptides 0.982776453296096 -0.0173735974173107 60 3 0.00282485875706215 1062 8688 11927,12774,329547 Atox1,Ccr5,Bpi R-MMU-927802 Nonsense-Mediated Decay (NMD) 0.983256978366592 -0.0168847704499503 108 7 0.00659133709981168 1062 8688 14109,267019,19946,20044,56040,225363,226517 Fau,Rps15a,Rpl30,Rps14,Rplp1,Etf1,Smg7 R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 0.983256978366592 -0.0168847704499503 108 7 0.00659133709981168 1062 8688 226517,20044,225363,56040,19946,267019,14109 Smg7,Rps14,Etf1,Rplp1,Rpl30,Rps15a,Fau R-MMU-5693607 Processing of DNA double-strand break ends 0.983405857955897 -0.0167333671826082 73 4 0.00376647834274953 1062 8688 12144,223970,225182,70620 Blm,Rmi2,Rbbp8,Ube2v2 R-MMU-71291 Metabolism of amino acids and derivatives 0.983737676677987 -0.0163960062128617 234 19 0.0178907721280603 1062 8688 78920,228608,26440,12040,14718,21823,102857,22018,59010,15109,218442,11702,13371,15112,108682,12583,104816,13195,14660 Dlst,Smox,Psma1,Bckdhb,Got1,Th,Slc6a8,Tpo,Sqor,Hal,Serinc5,Amd1,Dio2,Hao1,Gpt2,Cdo1,Aspg,Ddc,Gls R-MMU-5693538 Homology Directed Repair 0.984542048550761 -0.0155786712505163 109 7 0.00659133709981168 1062 8688 223970,67967,57434,12144,225182,70620,19363 Rmi2,Pold3,Xrcc2,Blm,Rbbp8,Ube2v2,Rad51b R-MMU-69239 Synthesis of DNA 0.98507200896201 -0.0150405349369402 98 6 0.00564971751412429 1062 8688 67967,16881,19076,26440,17219,272551 Pold3,Lig1,Prim2,Psma1,Mcm6,Gins2 R-MMU-1592389 Activation of Matrix Metalloproteinases 0.985473385713081 -0.014633158626091 48 2 0.00188323917137476 1062 8688 17387,13039 Mmp14,Ctsl R-MMU-69206 G1/S Transition 0.985734740332905 -0.0143679866050326 110 7 0.00659133709981168 1062 8688 22390,73699,26440,19076,27401,17219,12545 Wee1,Ppp2r1b,Psma1,Prim2,Skp2,Mcm6,Cdc7 R-MMU-6798695 Neutrophil degranulation 0.986163221397317 -0.0139333991370486 561 53 0.0499058380414313 1062 8688 20868,329547,72157,100040563,74244,110078,56444,71884,68365,12505,66681,110173,18600,16498,66713,210992,11772,57349,104009,107767,52588,19261,69116,70495,18753,14569,353204,11674,15481,21938,80910,15289,269116,208795,11886,14134,19263,22596,14590,16415,110095,19276,13036,12306,544963,18772,29875,74096,78892,11717,442827,80860,19271 Stk10,Bpi,Pgm2,Dynlt1c,Atg7,Pygb,Actr10,Chit1,Rab14,Cd44,Pgm1,Manba,Padi2,Kcnab2,Actr2,Lpcat1,Ap2a2,Ppbp,Qsox1,Scamp1,Tspan14,Sirpa,Ubr4,Atp6ap2,Prkcd,Gdi2,Aldoart1,Aldoa,Hspa8,Tnfrsf1b,Gpr84,Hmgb1,Nfasc,Tmem63a,Asah1,Fcnb,Ptprb,Xrcc5,Ggh,Itgb2l,Pygl,Ptprn2,Ctsh,Anxa2,Iqgap2,Pkp1,Iqgap1,Hvcn1,Crispld2,Ampd3,Rab44,Ghdc,Ptprj R-MMU-211897 Cytochrome P450 - arranged by substrate type 0.98627947736234 -0.0138155189418664 99 6 0.00564971751412429 1062 8688 21391,13120,230639,232174,11622,17978 Tbxas1,Cyp4b1,Cyp4a29,Cyp26b1,Ahr,Ncoa2 R-MMU-73728 RNA Polymerase I Promoter Opening 0.986579916784798 -0.0135109463750916 33 1 0.000941619585687382 1062 8688 17191 Mbd2 R-MMU-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 0.988226609826744 -0.0118432453609331 34 1 0.000941619585687382 1062 8688 67967 Pold3 R-MMU-5689901 Metalloprotease DUBs 0.988226609826744 -0.0118432453609331 34 1 0.000941619585687382 1062 8688 18519 Kat2b R-MMU-1799339 SRP-dependent cotranslational protein targeting to membrane 0.988311819968363 -0.0117570237723346 89 5 0.00470809792843691 1062 8688 19946,267019,14109,20044,56040 Rpl30,Rps15a,Fau,Rps14,Rplp1 R-MMU-69242 S Phase 0.988508405198948 -0.0115581334243604 124 8 0.00753295668549906 1062 8688 26440,19076,22390,16881,67967,17219,27401,272551 Psma1,Prim2,Wee1,Lig1,Pold3,Mcm6,Skp2,Gins2 R-MMU-73856 RNA Polymerase II Transcription Termination 0.988562344959609 -0.0115035680926235 64 3 0.00282485875706215 1062 8688 73826,66231,228410 Poldip3,Thoc7,Cstf3 R-MMU-109688 Cleavage of Growing Transcript in the Termination Region 0.988562344959609 -0.0115035680926235 64 3 0.00282485875706215 1062 8688 66231,73826,228410 Thoc7,Poldip3,Cstf3 R-MMU-5696398 Nucleotide Excision Repair 0.990250779331241 -0.00979705547588586 103 6 0.00564971751412429 1062 8688 67967,16881,227195,108679,225280,70620 Pold3,Lig1,Ino80d,Cops8,Ino80c,Ube2v2 R-MMU-674695 RNA Polymerase II Pre-transcription Events 0.990635989209303 -0.00940812876989137 79 4 0.00376647834274953 1062 8688 228980,83602,13716,72504 Taf4,Gtf2a1,Ell,Taf4b R-MMU-69202 Cyclin E associated events during G1/S transition 0.990702300796663 -0.00934119261091355 66 3 0.00282485875706215 1062 8688 22390,26440,27401 Wee1,Psma1,Skp2 R-MMU-69656 Cyclin A:Cdk2-associated events at S phase entry 0.990702300796663 -0.00934119261091355 66 3 0.00282485875706215 1062 8688 22390,26440,27401 Wee1,Psma1,Skp2 R-MMU-5696400 Dual Incision in GG-NER 0.990939062523808 -0.00910223743703221 36 1 0.000941619585687382 1062 8688 67967 Pold3 R-MMU-156827 L13a-mediated translational silencing of Ceruloplasmin expression 0.991058395755609 -0.00898182029780046 104 6 0.00564971751412429 1062 8688 19946,68135,14109,267019,56040,20044 Rpl30,Eif3h,Fau,Rps15a,Rplp1,Rps14 R-MMU-351202 Metabolism of polyamines 0.991500313989839 -0.00853601434070333 80 4 0.00376647834274953 1062 8688 26440,228608,11702,102857 Psma1,Smox,Amd1,Slc6a8 R-MMU-5658442 Regulation of RAS by GAPs 0.991621940183489 -0.00841335302363501 67 3 0.00282485875706215 1062 8688 26440,69601,54153 Psma1,Dab2ip,Rasa4 R-MMU-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 0.991772843422014 -0.00826118640500409 53 2 0.00188323917137476 1062 8688 15481,26440 Hspa8,Psma1 R-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic 0.991772843422014 -0.00826118640500409 53 2 0.00188323917137476 1062 8688 72772,77038 Rint1,Arfgap2 R-MMU-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 0.992487548356214 -0.00754081223630221 106 6 0.00564971751412429 1062 8688 19946,14109,68135,267019,56040,20044 Rpl30,Fau,Eif3h,Rps15a,Rplp1,Rps14 R-MMU-69541 Stabilization of p53 0.992663836392019 -0.00736320559368258 54 2 0.00188323917137476 1062 8688 26440,17246 Psma1,Mdm2 R-MMU-69002 DNA Replication Pre-Initiation 0.993658400918233 -0.00636179243860899 83 4 0.00376647834274953 1062 8688 19076,26440,17219,12545 Prim2,Psma1,Mcm6,Cdc7 R-MMU-68874 M/G1 Transition 0.993658400918233 -0.00636179243860899 83 4 0.00376647834274953 1062 8688 12545,17219,26440,19076 Cdc7,Mcm6,Psma1,Prim2 R-MMU-3214858 RMTs methylate histone arginines 0.99388366135706 -0.00613512006365237 70 3 0.00282485875706215 1062 8688 239985,13435,140858 Arid1b,Dnmt3a,Wdr5 R-MMU-453279 Mitotic G1-G1/S phases 0.993937704437908 -0.00608074588115109 132 8 0.00753295668549906 1062 8688 19076,26440,22390,73699,12571,17219,27401,12545 Prim2,Psma1,Wee1,Ppp2r1b,Cdk6,Mcm6,Skp2,Cdc7 R-MMU-74160 Gene Expression 0.994101403357536 -0.00591606207854744 1163 117 0.110169491525424 1062 8688 107686,228829,21834,68135,225182,21676,14791,327987,67225,14660,13435,11569,22630,66446,76938,57316,66596,76130,104625,433586,26424,14782,227743,50912,70428,70239,218210,73826,218772,11737,52463,13716,26931,26992,216080,20044,26399,18750,97064,76522,15481,209456,67381,68981,26440,77976,228980,56187,213895,18519,57748,21420,22184,67178,22628,75627,67486,78651,19883,67678,78929,21679,226517,21388,19946,319177,20393,12393,15388,17191,214133,225998,13197,218343,216987,228410,20620,18718,192657,83814,18607,74326,74108,71805,12450,66231,225363,56040,107939,73699,67285,80707,269252,17246,108099,106931,14109,223970,20602,229279,71702,22337,267019,15370,319801,68576,26381,72587,12144,18753,13433,83602,68979,66313,105787,19664,72504 Snrpd2,Phf20,Thrb,Eif3h,Rbbp8,Tead1,Emg1,Med13,Rnpc3,Gls,Dnmt3a,Aebp2,Ywhaq,Exosc7,Rbm17,C1d,Gtf3a,Las1l,Cnot6,Maml3,Nr5a2,Gsr,Mapkap1,Exosc10,Polr3b,Gtf3c5,Nup153,Poldip3,Rarb,Anp32a,Tet1,Ell,Ppp2r5c,Brd7,Ube2d1,Rps14,Map2k6,Prkca,Wwtr1,Lsm8,Hspa8,Trp53bp2,Med4,Snrpa1,Psma1,Nuak1,Taf4,Rabggta,Bms1,Kat2b,Jmy,Tfap2c,Zrsr2,Zmat5,Ywhag,Snapc1,Polr3g,Lsm6,Rora,Lsm3,Polr3h,Tead4,Smg7,Tbx5,Rpl30,Hist1h2ba,Sgk1,Runx2,Hnrnpl,Mbd2,Tet2,Rorb,Gadd45a,Ttc37,Utp6,Cstf3,Plk2,Pip4k2a,Ell2,Nedd4l,Pdpk1,Hnrnpr,Parn,Nup93,Ccng1,Thoc7,Etf1,Rplp1,Pom121,Ppp2r1b,Cwc27,Wwox,Gtf3c4,Mdm2,Prkag2,Kctd1,Fau,Rmi2,Ncor2,Hnrnpa3,Cdc5l,Vdr,Rps15a,Nr4a1,Tigar,Lamtor5,Esrrg,Pan3,Blm,Prkcd,Dnmt1,Gtf2a1,Nol11,Smurf2,Prkaa1,Rbpj,Taf4b R-MMU-4641258 Degradation of DVL 0.994807182999486 -0.00520634653262821 57 2 0.00188323917137476 1062 8688 26440,13542 Psma1,Dvl1 R-MMU-774815 Nucleosome assembly 0.995293162594591 -0.00471794944668163 41 1 0.000941619585687382 1062 8688 12617 Cenpc1 R-MMU-606279 Deposition of new CENPA-containing nucleosomes at the centromere 0.995293162594591 -0.00471794944668163 41 1 0.000941619585687382 1062 8688 12617 Cenpc1 R-MMU-5696395 Formation of Incision Complex in GG-NER 0.995293162594591 -0.00471794944668163 41 1 0.000941619585687382 1062 8688 70620 Ube2v2 R-MMU-6811440 Retrograde transport at the Trans-Golgi-Network 0.995293162594591 -0.00471794944668163 41 1 0.000941619585687382 1062 8688 68299 Vps53 R-MMU-211981 Xenobiotics 0.995293162594591 -0.00471794944668163 41 1 0.000941619585687382 1062 8688 11622 Ahr R-MMU-5676590 NIK-->noncanonical NF-kB signaling 0.995374576089132 -0.00463615428518478 58 2 0.00188323917137476 1062 8688 12234,26440 Btrc,Psma1 R-MMU-4608870 Asymmetric localization of PCP proteins 0.995374576089132 -0.00463615428518478 58 2 0.00188323917137476 1062 8688 26440,66313 Psma1,Smurf2 R-MMU-6799198 Complex I biogenesis 0.995374576089132 -0.00463615428518478 58 2 0.00188323917137476 1062 8688 68375,239760 Ndufa8,Ndufa11b R-MMU-5607761 Dectin-1 mediated noncanonical NF-kB signaling 0.995374576089132 -0.00463615428518478 58 2 0.00188323917137476 1062 8688 12234,26440 Btrc,Psma1 R-MMU-72737 Cap-dependent Translation Initiation 0.995585568151992 -0.00442420422253724 112 6 0.00564971751412429 1062 8688 19946,68135,14109,267019,56040,20044 Rpl30,Eif3h,Fau,Rps15a,Rplp1,Rps14 R-MMU-72613 Eukaryotic Translation Initiation 0.995585568151992 -0.00442420422253724 112 6 0.00564971751412429 1062 8688 14109,267019,68135,19946,56040,20044 Fau,Rps15a,Eif3h,Rpl30,Rplp1,Rps14 R-MMU-187577 SCF(Skp2)-mediated degradation of p27/p21 0.99588100939133 -0.00412749701706712 59 2 0.00188323917137476 1062 8688 26440,27401 Psma1,Skp2 R-MMU-611105 Respiratory electron transport 0.995998727380393 -0.00400929912888473 74 3 0.00282485875706215 1062 8688 68375,239760,110842 Ndufa8,Ndufa11b,Etfa R-MMU-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 0.995998727380393 -0.00400929912888473 74 3 0.00282485875706215 1062 8688 108679,16881,67967 Cops8,Lig1,Pold3 R-MMU-212165 Epigenetic regulation of gene expression 0.996304901385877 -0.00370194235507328 138 8 0.00753295668549906 1062 8688 11569,13435,18519,214133,17191,319177,52463,13433 Aebp2,Dnmt3a,Kat2b,Tet2,Mbd2,Hist1h2ba,Tet1,Dnmt1 R-MMU-73894 DNA Repair 0.996339855294691 -0.0036668594245107 269 20 0.0188323917137476 1062 8688 225280,51869,67196,12144,55982,16881,108679,67967,70620,19363,227195,26383,14088,108138,14048,22596,26419,57434,223970,225182 Ino80c,Rif1,Ube2t,Blm,Paxip1,Lig1,Cops8,Pold3,Ube2v2,Rad51b,Ino80d,Fto,Fancc,Xrcc4,Eya1,Xrcc5,Mapk8,Xrcc2,Rmi2,Rbbp8 R-MMU-6805567 Keratinization 0.996412671226957 -0.0035937786667857 150 9 0.00847457627118644 1062 8688 18772,74176,16680,227937,64058,69661,16666,13512,71529 Pkp1,Tgm5,Krt84,Pkp4,Perp,2310061N02Rik,Krt16,Dsg3,Kazn R-MMU-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 0.996735973687063 -0.00326936486677459 61 2 0.00188323917137476 1062 8688 67967,16881 Pold3,Lig1 R-MMU-5358346 Hedgehog ligand biogenesis 0.996735973687063 -0.00326936486677459 61 2 0.00188323917137476 1062 8688 26440,226861 Psma1,Hhat R-MMU-5578749 Transcriptional regulation by small RNAs 0.996769894767469 -0.00323533328357642 76 3 0.00282485875706215 1062 8688 218210,71805,107939 Nup153,Nup93,Pom121 R-MMU-73893 DNA Damage Bypass 0.996823283408755 -0.00318177306689523 44 1 0.000941619585687382 1062 8688 67967 Pold3 R-MMU-2559586 DNA Damage/Telomere Stress Induced Senescence 0.996823283408755 -0.00318177306689523 44 1 0.000941619585687382 1062 8688 16906 Lmnb1 R-MMU-69563 p53-Dependent G1 DNA Damage Response 0.99709542251392 -0.00290880395732574 62 2 0.00188323917137476 1062 8688 17246,26440 Mdm2,Psma1 R-MMU-69580 p53-Dependent G1/S DNA damage checkpoint 0.99709542251392 -0.00290880395732574 62 2 0.00188323917137476 1062 8688 17246,26440 Mdm2,Psma1 R-MMU-6796648 TP53 Regulates Transcription of DNA Repair Genes 0.9972135741233 -0.00279031518781518 45 1 0.000941619585687382 1062 8688 13716 Ell R-MMU-211859 Biological oxidations 0.997220279059303 -0.00278359153940465 231 16 0.0150659133709981 1062 8688 242585,23972,228608,11622,13120,230639,69065,232174,17978,54486,57344,66112,216558,108645,21391,18113 Slc35d1,Papss2,Smox,Ahr,Cyp4b1,Cyp4a29,Chac1,Cyp26b1,Ncoa2,Hpgds,As3mt,Marc1,Ugp2,Mat2b,Tbxas1,Nnmt R-MMU-72766 Translation 0.997364770988988 -0.00263870733912035 130 7 0.00659133709981168 1062 8688 20044,225363,56040,19946,267019,68135,14109 Rps14,Etf1,Rplp1,Rpl30,Rps15a,Eif3h,Fau R-MMU-5334118 DNA methylation 0.997395577037888 -0.0026078203717382 78 3 0.00282485875706215 1062 8688 319177,13435,13433 Hist1h2ba,Dnmt3a,Dnmt1 R-MMU-1428517 The citric acid (TCA) cycle and respiratory electron transport 0.997576763600978 -0.0024261771881231 143 8 0.00753295668549906 1062 8688 78920,239760,68375,28080,20917,14651,110842,16828 Dlst,Ndufa11b,Ndufa8,Atp5o,Suclg2,Hagh,Etfa,Ldha R-MMU-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 0.997587206862594 -0.00241570861333884 131 7 0.00659133709981168 1062 8688 319177,218772,55982,13654,231051,17979,140858 Hist1h2ba,Rarb,Paxip1,Egr2,Kmt2c,Ncoa3,Wdr5 R-MMU-5619507 Activation of HOX genes during differentiation 0.997587206862594 -0.00241570861333884 131 7 0.00659133709981168 1062 8688 218772,319177,140858,231051,17979,55982,13654 Rarb,Hist1h2ba,Wdr5,Kmt2c,Ncoa3,Paxip1,Egr2 R-MMU-69615 G1/S DNA Damage Checkpoints 0.997701466793157 -0.0023011788891983 64 2 0.00188323917137476 1062 8688 26440,17246 Psma1,Mdm2 R-MMU-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 0.997856297967954 -0.00214600305030055 47 1 0.000941619585687382 1062 8688 108069 Grm3 R-MMU-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 0.997856297967954 -0.00214600305030055 47 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-73762 RNA Polymerase I Transcription Initiation 0.998119764196023 -0.0018820056661701 48 1 0.000941619585687382 1062 8688 18519 Kat2b R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 0.998350876512166 -0.00165048478881451 49 1 0.000941619585687382 1062 8688 69608 Sec24d R-MMU-68867 Assembly of the pre-replicative complex 0.998384479808524 -0.0016168265513777 67 2 0.00188323917137476 1062 8688 26440,17219 Psma1,Mcm6 R-MMU-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 0.998449508571182 -0.00155169468457311 97 4 0.00376647834274953 1062 8688 239760,110842,28080,68375 Ndufa11b,Etfa,Atp5o,Ndufa8 R-MMU-69017 CDK-mediated phosphorylation and removal of Cdc6 0.998553604750951 -0.0014474422884004 50 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-1640170 Cell Cycle 0.99873137467169 -0.00126943071464942 596 51 0.0480225988700565 1062 8688 16906,26931,22194,223970,17120,22390,18750,17219,27401,59021,216080,226747,12234,226849,83922,26440,16881,12144,73738,70620,272551,381644,83431,71175,18005,22628,19076,56430,12617,225182,319177,13191,22630,64009,19088,12237,71648,56317,71805,67967,218210,12571,16905,12545,107995,22367,268930,17246,73699,259279,107939 Lmnb1,Ppp2r5c,Ube2e1,Rmi2,Mad1l1,Wee1,Prkca,Mcm6,Skp2,Rab2a,Ube2d1,Ahctf1,Btrc,Ppp2r5a,Cep41,Psma1,Lig1,Blm,Haus7,Ube2v2,Gins2,Cep135,Ndel1,Nipbl,Nek2,Ywhag,Prim2,Clip1,Cenpc1,Rbbp8,Hist1h2ba,Dctn1,Ywhaq,Syne1,Prkar2b,Bub3,Optn,Anapc7,Nup93,Pold3,Nup153,Cdk6,Lmna,Cdc7,Cdc20,Vrk1,Pkmyt1,Mdm2,Ppp2r1b,Tubgcp3,Pom121 R-MMU-69229 Ubiquitin-dependent degradation of Cyclin D1 0.998731432010833 -0.00126937330267356 51 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-350562 Regulation of ornithine decarboxylase (ODC) 0.998731432010833 -0.00126937330267356 51 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-349425 Autodegradation of the E3 ubiquitin ligase COP1 0.998731432010833 -0.00126937330267356 51 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-75815 Ubiquitin-dependent degradation of Cyclin D 0.998731432010833 -0.00126937330267356 51 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-211945 Phase 1 - Functionalization of compounds 0.998786273769169 -0.00121446339304825 151 8 0.00753295668549906 1062 8688 228608,66112,11622,21391,13120,230639,232174,17978 Smox,Marc1,Ahr,Tbxas1,Cyp4b1,Cyp4a29,Cyp26b1,Ncoa2 R-MMU-68949 Orc1 removal from chromatin 0.998866557124294 -0.00113408570787042 70 2 0.00188323917137476 1062 8688 17219,26440 Mcm6,Psma1 R-MMU-69052 Switching of origins to a post-replicative state 0.998866557124294 -0.00113408570787042 70 2 0.00188323917137476 1062 8688 17219,26440 Mcm6,Psma1 R-MMU-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 0.998887414297368 -0.00111320508555842 52 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-69613 p53-Independent G1/S DNA damage checkpoint 0.998887414297368 -0.00111320508555842 52 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-69610 p53-Independent DNA Damage Response 0.998887414297368 -0.00111320508555842 52 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.999006732413858 -0.000993761203280353 115 5 0.00470809792843691 1062 8688 16412,74603,16415,71326,54698 Itgb1,Cd200r3,Itgb2l,Treml1,Crtam R-MMU-69300 Removal of licensing factors from origins 0.999105896212 -0.000894503737207482 72 2 0.00188323917137476 1062 8688 26440,17219 Psma1,Mcm6 R-MMU-6781823 Formation of TC-NER Pre-Incision Complex 0.99914424045444 -0.000856125916792189 54 1 0.000941619585687382 1062 8688 108679 Cops8 R-MMU-73857 RNA Polymerase II Transcription 0.999182448494898 -0.000817885882593664 143 7 0.00659133709981168 1062 8688 228980,228410,73826,66231,72504,83602,13716 Taf4,Cstf3,Poldip3,Thoc7,Taf4b,Gtf2a1,Ell R-MMU-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 0.999249500673663 -0.000750781091942216 55 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-372790 Signaling by GPCR 0.999280654164521 -0.00071960468883865 1331 129 0.121468926553672 1062 8688 216148,73699,18441,18573,13614,18590,258922,319239,16801,18607,12671,108069,20311,71111,320127,14182,226970,50780,15552,54409,14573,20779,226849,18753,14309,230972,240168,269608,12314,17967,109934,11876,239766,20297,16590,65086,19228,16452,71704,238377,238871,19049,16706,54126,18578,213649,76089,78134,19220,69601,13610,18166,13605,171469,14184,11551,20741,207212,16185,11549,20663,18750,50501,18610,26946,18673,14811,11554,84112,20742,26931,14708,56066,110312,64214,258153,12919,13649,12323,225192,14164,18155,67603,67839,54153,242851,11555,57349,12774,13617,259040,11553,15466,13869,110168,20300,14172,227333,16439,14701,53972,12778,22045,226278,235611,19088,18706,14745,381413,11515,80910,258830,11820,18783,217480,16443,235584,109648,14526,56696,11548,26440,12921,380921,18430,16451,20111,20315,24001 Shc2,Ppp2r1b,P2ry1,Pde1a,Edn1,Pdgfa,Olfr267,Npsr1,Arhgef1,Pdpk1,Chrm3,Grm3,Cxcl5,Gpr39,Dgki,Fgfr1,Arhgef4,Rgs3,Htr1d,Ramp2,Gdnf,Src,Ppp2r5a,Prkcd,Fshr,Arhgef16,Rasgrp3,Plekhg5,Calm2,Ncam1,Abr,Artn,Rtp1,Ccl20,Kit,Lpar3,Pth1r,Jak2,Arhgef3,Gpr68,Pde4d,Ppp1r1b,Ksr1,Arhgef7,Pde4b,Arhgef19,Rapgef2,Lpar4,Ptgfr,Dab2ip,S1pr3,Npy1r,Ect2,Gpr37l1,Fgfr3,Adra2a,Sptb,Arhgef17,Il2rb,Adra1a,Sos2,Prkca,Prok2,Pdyn,Trpc7,Phb,Grin2a,Adrb1,Sucnr1,Sptbn1,Ppp2r5c,Gng7,Cxcl11,Pmch,Rgs18,Olfr412,Crhbp,Egfr,Camk2b,Hrh4,Fgf1,Pnoc,Dusp6,Gpsm1,Rasa4,Gnat3,Adrb2,Ppbp,Ccr5,Ednra,Olfr1416,Adra2c,Hrh2,Erbb4,Gpr18,Ccl25,Fgf18,Dgkd,Itpr2,Gng12,Ngef,Ackr3,Trhr,Prlhr,Plxnb1,Prkar2b,Pik3ca,Lpar1,Gpr176,Adcy9,Gpr84,Olfr103,App,Pla2g4a,Dgkb,Itsn1,Dusp7,Npy,Gcg,Gpr132,Adra1b,Psma1,Crhr1,Dgkh,Oxtr,Jak1,Rps6ka1,Cxcl12,Tiam2 R-MMU-69304 Regulation of DNA replication 0.999374392487804 -0.000625803286231588 75 2 0.00188323917137476 1062 8688 26440,17219 Psma1,Mcm6 R-MMU-1221633 Meiotic Synapsis 0.999392148490659 -0.000608036325967484 106 4 0.00376647834274953 1062 8688 64009,16906,319177,16905 Syne1,Lmnb1,Hist1h2ba,Lmna R-MMU-1221632 Meiotic synapsis 0.999392148490659 -0.000608036325967484 106 4 0.00376647834274953 1062 8688 319177,16905,64009,16906 Hist1h2ba,Lmna,Syne1,Lmnb1 R-MMU-427413 NoRC negatively regulates rRNA expression 0.999439941953248 -0.000560214937841105 92 3 0.00282485875706215 1062 8688 13433,17191,319177 Dnmt1,Mbd2,Hist1h2ba R-MMU-112382 Formation of RNA Pol II elongation complex 0.999493821567179 -0.000506306584370933 58 1 0.000941619585687382 1062 8688 13716 Ell R-MMU-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 0.999493821567179 -0.000506306584370933 58 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-68827 CDT1 association with the CDC6:ORC:origin complex 0.999493821567179 -0.000506306584370933 58 1 0.000941619585687382 1062 8688 26440 Psma1 R-MMU-75955 RNA Polymerase II Transcription Elongation 0.999493821567179 -0.000506306584370933 58 1 0.000941619585687382 1062 8688 13716 Ell R-MMU-5689603 UCH proteinases 0.999552040093093 -0.000448060270920146 94 3 0.00282485875706215 1062 8688 225280,227195,26440 Ino80c,Ino80d,Psma1 R-MMU-1500620 Meiosis 0.999554003347675 -0.000446096138412931 123 5 0.00470809792843691 1062 8688 64009,16906,12144,16905,319177 Syne1,Lmnb1,Blm,Lmna,Hist1h2ba R-MMU-73854 RNA Polymerase I Promoter Clearance 0.999656112105993 -0.00034394703700838 80 2 0.00188323917137476 1062 8688 18519,17191 Kat2b,Mbd2 R-MMU-73864 RNA Polymerase I Transcription 0.999695040807599 -0.000305005701911915 81 2 0.00188323917137476 1062 8688 18519,17191 Kat2b,Mbd2 R-MMU-6782135 Dual incision in TC-NER 0.999700675305597 -0.000299369500981126 62 1 0.000941619585687382 1062 8688 67967 Pold3 R-MMU-5250924 B-WICH complex positively regulates rRNA expression 0.999737527022022 -0.000262507430038765 63 1 0.000941619585687382 1062 8688 18519 Kat2b R-MMU-1236975 Antigen processing-Cross presentation 0.999744621720728 -0.000255410893857811 99 3 0.00282485875706215 1062 8688 26440,17970,16419 Psma1,Ncf2,Itgb5 R-MMU-5250941 Negative epigenetic regulation of rRNA expression 0.999771904877419 -0.000228121140230042 100 3 0.00282485875706215 1062 8688 13433,17191,319177 Dnmt1,Mbd2,Hist1h2ba R-MMU-211000 Gene Silencing by RNA 0.999870708743435 -0.00012929961539955 105 3 0.00282485875706215 1062 8688 107939,71805,218210 Pom121,Nup93,Nup153 R-MMU-573389 NoRC negatively regulates rRNA expression 0.999908962419793 -9.10417243791057e-05 91 2 0.00188323917137476 1062 8688 319177,13433 Hist1h2ba,Dnmt1 R-MMU-912497 Meiotic Recombination 0.999908962419793 -9.10417243791057e-05 91 2 0.00188323917137476 1062 8688 12144,319177 Blm,Hist1h2ba R-MMU-427389 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 0.999945820225634 -5.4181242143309e-05 75 1 0.000941619585687382 1062 8688 319177 Hist1h2ba R-MMU-5250913 Positive epigenetic regulation of rRNA expression 0.999988647349757 -1.13527146844223e-05 108 2 0.00188323917137476 1062 8688 319177,18519 Hist1h2ba,Kat2b R-MMU-388396 GPCR downstream signaling 0.999995840072299 -4.15993635337809e-06 1065 88 0.0828625235404896 1062 8688 18607,319239,16801,258922,13614,18573,18441,258153,64214,110312,56066,11555,320127,242851,20311,67839,108069,12671,18155,225192,230972,18753,14309,11553,259040,54409,226970,15552,50780,13617,12774,57349,16439,227333,20300,110168,109934,15466,269608,18706,14745,238871,238377,71704,235611,16452,19228,12778,22045,65086,53972,20297,239766,13605,18166,217480,11820,13610,258830,19220,78134,213649,80910,381413,11515,18578,54126,20663,207212,11549,16185,11548,11551,56696,14526,109648,16443,24001,84112,20315,11554,16451,18430,18610,26946,50501,380921,12921 Pdpk1,Npsr1,Arhgef1,Olfr267,Edn1,Pde1a,P2ry1,Olfr412,Rgs18,Pmch,Cxcl11,Adrb2,Dgki,Gnat3,Cxcl5,Gpsm1,Grm3,Chrm3,Pnoc,Hrh4,Arhgef16,Prkcd,Fshr,Adra2c,Olfr1416,Ramp2,Arhgef4,Htr1d,Rgs3,Ednra,Ccr5,Ppbp,Itpr2,Dgkd,Ccl25,Gpr18,Abr,Hrh2,Plekhg5,Pik3ca,Lpar1,Pde4d,Gpr68,Arhgef3,Plxnb1,Jak2,Pth1r,Ackr3,Trhr,Lpar3,Ngef,Ccl20,Rtp1,Ect2,Npy1r,Dgkb,App,S1pr3,Olfr103,Ptgfr,Lpar4,Arhgef19,Gpr84,Gpr176,Adcy9,Pde4b,Arhgef7,Sos2,Arhgef17,Adra1a,Il2rb,Adra1b,Adra2a,Gpr132,Gcg,Npy,Itsn1,Tiam2,Sucnr1,Cxcl12,Adrb1,Jak1,Oxtr,Pdyn,Trpc7,Prok2,Dgkh,Crhr1 R-MMU-381753 Olfactory Signaling Pathway 0.999999999946065 -5.3935095620231e-11 535 5 0.00470809792843691 1062 8688 259040,258830,258922,258153,239766 Olfr1416,Olfr103,Olfr267,Olfr412,Rtp1