TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP412 Oxidative Stress 0.911466176454416 -0.092700793117017 28 2 0.00296296296296296 675 4946 20655,14782 Sod1,Gsr WP1244 Estrogen signaling 0.916621531546551 -0.0870606165147287 77 7 0.0103703703703704 675 4946 18706,16150,208727,20779,56233,26420,216148 Pik3ca,Ikbkb,Hdac4,Src,Hdac7,Mapk9,Shc2 WP200 Complement Activation, Classical Pathway 0.917815303053837 -0.0857591035345224 17 1 0.00148148148148148 675 4946 110382 C8b WP166 Apoptosis Modulation by HSP70 0.929070054618776 -0.0735711343797657 18 1 0.00148148148148148 675 4946 14082 Fadd WP2292 Chemokine signaling pathway 0.93257590419306 -0.069804732178397 193 20 0.0296296296296296 675 4946 18479,24001,20311,16150,14708,11515,14701,56066,18753,12774,20663,57349,20315,18706,140580,20848,216148,20297,20300,16452 Pak1,Tiam2,Cxcl5,Ikbkb,Gng7,Adcy9,Gng12,Cxcl11,Prkcd,Ccr5,Sos2,Ppbp,Cxcl12,Pik3ca,Elmo1,Stat3,Shc2,Ccl20,Ccl25,Jak2 WP3626 Microglia Pathogen Phagocytosis Pathway 0.93257905409327 -0.0698013545499632 41 3 0.00444444444444444 675 4946 18706,17970,234779 Pik3ca,Ncf2,Plcg2 WP234 Peptide GPCRs 0.935892606207947 -0.0662545460446549 71 6 0.00888888888888889 675 4946 22045,14309,18166,12774,18430,13617 Trhr,Fshr,Npy1r,Ccr5,Oxtr,Ednra WP1398 Orphan GPCRs 0.938785499664108 -0.0631682607315959 19 1 0.00148148148148148 675 4946 68526 Gpr155 WP1263 Mitochondrial Gene Expression 0.938785499664108 -0.0631682607315959 19 1 0.00148148148148148 675 4946 19055 Ppp3ca WP87 Nucleotide Metabolism 0.938785499664108 -0.0631682607315959 19 1 0.00148148148148148 675 4946 20133 Rrm1 WP449 Complement and Coagulation Cascades 0.938965762529493 -0.0629762620685489 62 5 0.00740740740740741 675 4946 18816,22371,12258,21824,17221 Serpinf2,Vwf,Serping1,Thbd,Cd46 WP1496 Oxidative Damage 0.939371276178304 -0.0625444826309347 42 3 0.00444444444444444 675 4946 22031,21938,13197 Traf3,Tnfrsf1b,Gadd45a WP164 Glutathione metabolism 0.94717189862665 -0.0542746831275344 20 1 0.00148148148148148 675 4946 14782 Gsr WP2087 miRNA regulation of DNA Damage Response 0.953587621844868 -0.0475239632032138 65 5 0.00740740740740741 675 4946 13197,12571,17873,12450,17246 Gadd45a,Cdk6,Gadd45b,Ccng1,Mdm2 WP216 Striated Muscle Contraction 0.956131299308957 -0.0448600329879504 45 3 0.00444444444444444 675 4946 12373,17929,17930 Casq2,Myom1,Myom2 WP189 GPCRs, Class A Rhodopsin-like 0.959985499189303 -0.0408370996454793 228 23 0.0340740740740741 675 4946 11554,18441,12671,15466,19220,22045,81006,14762,59289,18166,11553,15552,84112,18430,11548,170732,12778,14309,11555,11549,171469,12774,11551 Adrb1,P2ry1,Chrm3,Hrh2,Ptgfr,Trhr,Gpr63,Gpr33,Ackr2,Npy1r,Adra2c,Htr1d,Sucnr1,Oxtr,Adra1b,Trhr2,Ackr3,Fshr,Adrb2,Adra1a,Gpr37l1,Ccr5,Adra2a WP57 Signal Transduction of S1P Receptor 0.960659090576249 -0.0401356774061412 22 1 0.00148148148148148 675 4946 13610 S1pr3 WP163 Cytoplasmic Ribosomal Proteins 0.976360910270759 -0.0239229758092263 102 8 0.0118518518518519 675 4946 20044,56040,20068,19946,114641,267019,14109,20111 Rps14,Rplp1,Rps17,Rpl30,Rpl31,Rps15a,Fau,Rps6ka1 WP1248 Oxidative phosphorylation 0.977399606366449 -0.0228596968815344 62 4 0.00592592592592593 675 4946 28080,70495,239760,68375 Atp5o,Atp6ap2,Ndufa11b,Ndufa8 WP307 Translation Factors 0.977488191469854 -0.0227690675333298 51 3 0.00444444444444444 675 4946 18459,68135,225363 Pabpc2,Eif3h,Etf1 WP1274 Oxidation by Cytochrome P450 0.979667740544576 -0.0205418050652994 40 2 0.00296296296296296 675 4946 13120,232174 Cyp4b1,Cyp26b1 WP108 Selenium metabolism/Selenoproteins 0.979903799676817 -0.020300875730965 52 3 0.00444444444444444 675 4946 13371,19946,20687 Dio2,Rpl30,Sp3 WP41 GPCRs, Other 0.984653162799167 -0.0154658188041125 164 14 0.0207407407407407 675 4946 15552,11554,56696,14369,319757,13617,170732,258153,11555,80910,71111,64378,14371,171469 Htr1d,Adrb1,Gpr132,Fzd7,Smo,Ednra,Trhr2,Olfr412,Adrb2,Gpr84,Gpr39,Gpr88,Fzd9,Gpr37l1 WP251 MAPK Cascade 0.985993465939183 -0.0141055512379872 29 1 0.00148148148148148 675 4946 26399 Map2k6 WP567 Eukaryotic Transcription Initiation 0.986105536778197 -0.0139918948353624 43 2 0.00296296296296296 675 4946 78929,70428 Polr3h,Polr3b WP519 Proteasome Degradation 0.998279953386108 -0.00172152759254708 59 2 0.00296296296296296 675 4946 216080,26440 Ube2d1,Psma1 WP295 Electron Transport Chain 0.99954451319937 -0.000455590566253342 109 5 0.00740740740740741 675 4946 226139,12867,68375,20463,28080 Cox15,Cox7c,Ndufa8,Cox7a2l,Atp5o WP1397 Odorant GPCRs 0.999956923763813 -4.3077163994746e-05 189 10 0.0148148148148148 675 4946 68526,80910,14762,81006,215798,381413,211577,171469,64378,233919 Gpr155,Gpr84,Gpr33,Gpr63,Adgrg6,Gpr176,Mrgprf,Gpr37l1,Gpr88,Gpr26 WP310 mRNA processing 0.999999965594787 -3.44052137413016e-08 484 31 0.0459259259259259 675 4946 20238,73826,231769,15388,102857,66446,229279,53791,20975,353258,14007,93686,56758,228410,268859,20044,207181,22184,75388,67225,68981,107686,66405,76522,76938,18459,108013,74326,67456,230603,19134 Atxn1,Poldip3,Sfswap,Hnrnpl,Slc6a8,Exosc7,Hnrnpa3,Tlr5,Synj2,Ltv1,Celf2,Rbfox2,Mbnl1,Cstf3,Rbfox1,Rps14,Rbms3,Zrsr2,Boll,Rnpc3,Snrpa1,Snrpd2,Mcts2,Lsm8,Rbm17,Pabpc2,Celf4,Hnrnpr,Ergic2,Ttc39a,Prpf4b