TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols ko00280 Valine, leucine and isoleucine degradation 0.900866130517197 -0.104398611194965 56 3 0.00403225806451613 744 8063 52538,93747,64059 Acaa2,Echs1,Oxct2a mmu00280 Valine, leucine and isoleucine degradation 0.900866130517197 -0.104398611194965 56 3 0.00403225806451613 744 8063 64059,93747,52538 Oxct2a,Echs1,Acaa2 M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate 0.902409438244383 -0.102686939245628 24 1 0.00134408602150538 744 8063 216558 Ugp2 mmu_M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate 0.902409438244383 -0.102686939245628 24 1 0.00134408602150538 744 8063 216558 Ugp2 mmu_M00427 Nuclear pore complex 0.902976333264303 -0.102058934918245 41 2 0.00268817204301075 744 8063 218210,71805 Nup153,Nup93 M00427 Nuclear pore complex 0.902976333264303 -0.102058934918245 41 2 0.00268817204301075 744 8063 218210,71805 Nup153,Nup93 mmu00860 Porphyrin and chlorophyll metabolism 0.902976333264303 -0.102058934918245 41 2 0.00268817204301075 744 8063 226139,107508 Cox15,Eprs ko00860 Porphyrin and chlorophyll metabolism 0.902976333264303 -0.102058934918245 41 2 0.00268817204301075 744 8063 107508,226139 Eprs,Cox15 mmu05310 Asthma 0.911441330007423 -0.0927280533558456 25 1 0.00134408602150538 744 8063 16153 Il10 ko05310 Asthma 0.911441330007423 -0.0927280533558456 25 1 0.00134408602150538 744 8063 16153 Il10 ko00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.911441330007423 -0.0927280533558456 25 1 0.00134408602150538 744 8063 329777 Pigk mmu00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.911441330007423 -0.0927280533558456 25 1 0.00134408602150538 744 8063 329777 Pigk ko03420 Nucleotide excision repair 0.923242272474131 -0.0798635952014907 44 2 0.00268817204301075 744 8063 67967,16881 Pold3,Lig1 mmu03420 Nucleotide excision repair 0.923242272474131 -0.0798635952014907 44 2 0.00268817204301075 744 8063 67967,16881 Pold3,Lig1 ko04950 Maturity onset diabetes of the young 0.927077577452168 -0.07571803034589 27 1 0.00134408602150538 744 8063 26424 Nr5a2 mmu04950 Maturity onset diabetes of the young 0.927077577452168 -0.07571803034589 27 1 0.00134408602150538 744 8063 26424 Nr5a2 mmu04650 Natural killer cell mediated cytotoxicity 0.928008315721538 -0.0747145853292559 118 7 0.00940860215053763 744 8063 216148,18706,18750,19057,18479,20663,19055 Shc2,Pik3ca,Prkca,Ppp3cc,Pak1,Sos2,Ppp3ca ko04650 Natural killer cell mediated cytotoxicity 0.928008315721538 -0.0747145853292559 118 7 0.00940860215053763 744 8063 18750,18706,216148,19055,18479,20663,19057 Prkca,Pik3ca,Shc2,Ppp3ca,Pak1,Sos2,Ppp3cc mmu03040 Spliceosome 0.932905168815749 -0.0694517244412807 133 8 0.010752688172043 744 8063 229279,67678,15481,76938,68981,107686,71702,76522 Hnrnpa3,Lsm3,Hspa8,Rbm17,Snrpa1,Snrpd2,Cdc5l,Lsm8 ko03040 Spliceosome 0.932905168815749 -0.0694517244412807 133 8 0.010752688172043 744 8063 67678,229279,71702,107686,76522,68981,76938,15481 Lsm3,Hnrnpa3,Cdc5l,Snrpd2,Lsm8,Snrpa1,Rbm17,Hspa8 ko00380 Tryptophan metabolism 0.934461207209332 -0.0677851647626782 46 2 0.00268817204301075 744 8063 93747,13195 Echs1,Ddc mmu00380 Tryptophan metabolism 0.934461207209332 -0.0677851647626782 46 2 0.00268817204301075 744 8063 13195,93747 Ddc,Echs1 ko00630 Glyoxylate and dicarboxylate metabolism 0.93995608012538 -0.061922128080526 29 1 0.00134408602150538 744 8063 15112 Hao1 mmu00630 Glyoxylate and dicarboxylate metabolism 0.93995608012538 -0.061922128080526 29 1 0.00134408602150538 744 8063 15112 Hao1 ko05330 Allograft rejection 0.942943416151144 -0.0587490022304979 64 3 0.00403225806451613 744 8063 16153,12487,16160 Il10,Cd28,Il12b mmu05330 Allograft rejection 0.942943416151144 -0.0587490022304979 64 3 0.00403225806451613 744 8063 16153,12487,16160 Il10,Cd28,Il12b mmu00591 Linoleic acid metabolism 0.952406149432599 -0.0487637076151808 50 2 0.00268817204301075 744 8063 18783,665270 Pla2g4a,Plb1 ko00591 Linoleic acid metabolism 0.952406149432599 -0.0487637076151808 50 2 0.00268817204301075 744 8063 665270,18783 Plb1,Pla2g4a ko04130 SNARE interactions in vesicular transport 0.959297720818137 -0.041553803041244 33 1 0.00134408602150538 744 8063 20908 Stx3 mmu04130 SNARE interactions in vesicular transport 0.959297720818137 -0.041553803041244 33 1 0.00134408602150538 744 8063 20908 Stx3 ko05150 Staphylococcus aureus infection 0.959514553770705 -0.041327795571558 52 2 0.00268817204301075 744 8063 17195,16153 Mbl2,Il10 mmu05150 Staphylococcus aureus infection 0.959514553770705 -0.041327795571558 52 2 0.00268817204301075 744 8063 17195,16153 Mbl2,Il10 mmu00040 Pentose and glucuronate interconversions 0.963068890890671 -0.0376303319538579 34 1 0.00134408602150538 744 8063 216558 Ugp2 ko00040 Pentose and glucuronate interconversions 0.963068890890671 -0.0376303319538579 34 1 0.00134408602150538 744 8063 216558 Ugp2 ko05168 Herpes simplex infection 0.96656439749738 -0.0340073529648054 215 13 0.0174731182795699 744 8063 72504,16160,27401,26419,228980,54721,16452,56489,216150,26420,14082,22031,16150 Taf4b,Il12b,Skp2,Mapk8,Taf4,Tyk2,Jak2,Ikbke,Cdc34,Mapk9,Fadd,Traf3,Ikbkb mmu05168 Herpes simplex infection 0.96656439749738 -0.0340073529648054 215 13 0.0174731182795699 744 8063 72504,16160,27401,228980,54721,26419,56489,16452,216150,16150,26420,14082,22031 Taf4b,Il12b,Skp2,Taf4,Tyk2,Mapk8,Ikbke,Jak2,Cdc34,Ikbkb,Mapk9,Fadd,Traf3 mmu00590 Arachidonic acid metabolism 0.969891354461022 -0.0305712194681031 89 4 0.00537634408602151 744 8063 665270,11684,230639,18783 Plb1,Alox12,Cyp4a29,Pla2g4a mmu00830 Retinol metabolism 0.969891354461022 -0.0305712194681031 89 4 0.00537634408602151 744 8063 20148,67442,230639,232174 Dhrs3,Retsat,Cyp4a29,Cyp26b1 ko00590 Arachidonic acid metabolism 0.969891354461022 -0.0305712194681031 89 4 0.00537634408602151 744 8063 230639,18783,11684,665270 Cyp4a29,Pla2g4a,Alox12,Plb1 ko00830 Retinol metabolism 0.969891354461022 -0.0305712194681031 89 4 0.00537634408602151 744 8063 20148,230639,67442,232174 Dhrs3,Cyp4a29,Retsat,Cyp26b1 ko00480 Glutathione metabolism 0.977204840435367 -0.0230589862385653 59 2 0.00268817204301075 744 8063 14782,20133 Gsr,Rrm1 mmu00480 Glutathione metabolism 0.977204840435367 -0.0230589862385653 59 2 0.00268817204301075 744 8063 20133,14782 Rrm1,Gsr mmu00260 Glycine, serine and threonine metabolism 0.979397589446 -0.0208176009728203 40 1 0.00134408602150538 744 8063 192166 Sardh ko00260 Glycine, serine and threonine metabolism 0.979397589446 -0.0208176009728203 40 1 0.00134408602150538 744 8063 192166 Sardh mmu05322 Systemic lupus erythematosus 0.980981527753917 -0.019201649610455 142 7 0.00940860215053763 744 8063 236663,16153,110382,319177,12487,109711,14811 H2al1j,Il10,C8b,Hist1h2ba,Cd28,Actn1,Grin2a ko05322 Systemic lupus erythematosus 0.980981527753917 -0.019201649610455 142 7 0.00940860215053763 744 8063 236663,110382,16153,319177,12487,109711,14811 H2al1j,C8b,Il10,Hist1h2ba,Cd28,Actn1,Grin2a mmu04962 Vasopressin-regulated water reabsorption 0.984614691238549 -0.0155048907470619 43 1 0.00134408602150538 744 8063 13426 Dync1i1 ko04962 Vasopressin-regulated water reabsorption 0.984614691238549 -0.0155048907470619 43 1 0.00134408602150538 744 8063 13426 Dync1i1 ko03050 Proteasome 0.988511996278089 -0.011554500604852 46 1 0.00134408602150538 744 8063 20422 Sem1 mmu03050 Proteasome 0.988511996278089 -0.011554500604852 46 1 0.00134408602150538 744 8063 20422 Sem1 mmu04211 Longevity regulating pathway 0.99177915638263 -0.00825482109608628 90 3 0.00403225806451613 744 8063 67605,105787,18706 Akt1s1,Prkaa1,Pik3ca mmu00983 Drug metabolism - other enzymes 0.992941740044249 -0.00708328730845732 51 1 0.00134408602150538 744 8063 22247 Umps ko00983 Drug metabolism - other enzymes 0.992941740044249 -0.00708328730845732 51 1 0.00134408602150538 744 8063 22247 Umps ko03010 Ribosome 0.994233756493849 -0.00578293247426225 177 8 0.010752688172043 744 8063 56040,19946,20044,64657,20068,68565,267019,14109 Rplp1,Rpl30,Rps14,Mrps10,Rps17,Mrps18a,Rps15a,Fau mmu03010 Ribosome 0.994233756493849 -0.00578293247426225 177 8 0.010752688172043 744 8063 267019,14109,68565,20068,64657,20044,19946,56040 Rps15a,Fau,Mrps18a,Rps17,Mrps10,Rps14,Rpl30,Rplp1 ko00140 Steroid hormone biosynthesis 0.997914390860194 -0.00208778705125593 87 2 0.00268817204301075 744 8063 56348,15487 Hsd17b12,Hsd17b3 mmu00140 Steroid hormone biosynthesis 0.997914390860194 -0.00208778705125593 87 2 0.00268817204301075 744 8063 56348,15487 Hsd17b12,Hsd17b3 mmu05416 Viral myocarditis 0.998089146633443 -0.00191268137592807 88 2 0.00268817204301075 744 8063 12487,24052 Cd28,Sgcd mmu05332 Graft-versus-host disease 0.998198526828009 -0.00180309777619985 65 1 0.00134408602150538 744 8063 12487 Cd28 ko05332 Graft-versus-host disease 0.998198526828009 -0.00180309777619985 65 1 0.00134408602150538 744 8063 12487 Cd28 mmu00982 Drug metabolism - cytochrome P450 0.998518114913593 -0.00148298416405043 67 1 0.00134408602150538 744 8063 226564 Fmo4 ko00982 Drug metabolism - cytochrome P450 0.998518114913593 -0.00148298416405043 67 1 0.00134408602150538 744 8063 226564 Fmo4 mmu04612 Antigen processing and presentation 0.998531382973898 -0.00146969650110616 91 2 0.00268817204301075 744 8063 15481,13039 Hspa8,Ctsl ko04612 Antigen processing and presentation 0.998531382973898 -0.00146969650110616 91 2 0.00268817204301075 744 8063 13039,15481 Ctsl,Hspa8 ko03013 RNA transport 0.998655400666061 -0.00134550411876262 167 6 0.00806451612903226 744 8063 18459,66231,68135,71805,218210,76884 Pabpc2,Thoc7,Eif3h,Nup93,Nup153,Cyfip2 mmu03013 RNA transport 0.998655400666061 -0.00134550411876262 167 6 0.00806451612903226 744 8063 76884,218210,71805,68135,18459,66231 Cyfip2,Nup153,Nup93,Eif3h,Pabpc2,Thoc7 ko03008 Ribosome biogenesis in eukaryotes 0.999841811784807 -0.000158200728268493 116 2 0.00268817204301075 744 8063 213895,14791 Bms1,Emg1 mmu03008 Ribosome biogenesis in eukaryotes 0.999841811784807 -0.000158200728268493 116 2 0.00268817204301075 744 8063 14791,213895 Emg1,Bms1 mmu04740 Olfactory transduction 0.999999999895088 -1.04912420624631e-10 1119 10 0.0134408602150538 744 8063 258922,12323,14708,259040,18573,258412,12314,257951,70405,258153 Olfr267,Camk2b,Gng7,Olfr1416,Pde1a,Olfr877,Calm2,Olfr987,Calml3,Olfr412 ko04740 Olfactory transduction 0.999999999895088 -1.04912420624631e-10 1119 10 0.0134408602150538 744 8063 12314,257951,70405,258153,258412,18573,259040,258922,14708,12323 Calm2,Olfr987,Calml3,Olfr412,Olfr877,Pde1a,Olfr1416,Olfr267,Gng7,Camk2b