TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols mmu00531 Glycosaminoglycan degradation 0.901358932910296 -0.103851728993201 21 1 0.00118906064209275 841 8063 15211 Hexa ko00531 Glycosaminoglycan degradation 0.901358932910296 -0.103851728993201 21 1 0.00118906064209275 841 8063 15211 Hexa mmu00190 Oxidative phosphorylation 0.904104007674138 -0.100810872471141 134 10 0.0118906064209275 841 8063 11974,75406,67184,69875,66052,17993,84682,66290,76429,66916 Atp6v0e,Ndufs7,Ndufa13,Ndufa11,Sdhc,Ndufs4,Cox4i2,Atp6v1g1,Lhpp,Ndufb7 ko00190 Oxidative phosphorylation 0.904104007674138 -0.100810872471141 134 10 0.0118906064209275 841 8063 84682,66290,76429,66916,75406,67184,11974,66052,69875,17993 Cox4i2,Atp6v1g1,Lhpp,Ndufb7,Ndufs7,Ndufa13,Atp6v0e,Sdhc,Ndufa11,Ndufs4 ko00591 Linoleic acid metabolism 0.905660662196025 -0.0990905881361697 50 3 0.00356718192627824 841 8063 18778,18784,18780 Pla2g1b,Pla2g5,Pla2g2a mmu00591 Linoleic acid metabolism 0.905660662196025 -0.0990905881361697 50 3 0.00356718192627824 841 8063 18784,18778,18780 Pla2g5,Pla2g1b,Pla2g2a ko00514 Other types of O-glycan biosynthesis 0.911674418798566 -0.0924723495777774 22 1 0.00118906064209275 841 8063 381694 B3glct mmu00514 Other types of O-glycan biosynthesis 0.911674418798566 -0.0924723495777774 22 1 0.00118906064209275 841 8063 381694 B3glct mmu00830 Retinol metabolism 0.913814958793681 -0.090127180109865 89 6 0.00713436385255648 841 8063 230639,20148,63857,232174,28200,13082 Cyp4a29,Dhrs3,Bco1,Cyp26b1,Dhrs4,Cyp26a1 ko00830 Retinol metabolism 0.913814958793681 -0.090127180109865 89 6 0.00713436385255648 841 8063 63857,230639,20148,13082,232174,28200 Bco1,Cyp4a29,Dhrs3,Cyp26a1,Cyp26b1,Dhrs4 mmu05150 Staphylococcus aureus infection 0.919213711212191 -0.0842366360964914 52 3 0.00356718192627824 841 8063 12268,18815,16415 C4b,Plg,Itgb2l ko05150 Staphylococcus aureus infection 0.919213711212191 -0.0842366360964914 52 3 0.00356718192627824 841 8063 18815,16415,12268 Plg,Itgb2l,C4b mmu05132 Salmonella infection 0.920603337121436 -0.0827260226637496 78 5 0.00594530321046373 841 8063 242687,19353,235661,26415,13426 Wasf2,Rac1,Dync1li1,Mapk13,Dync1i1 ko05132 Salmonella infection 0.920603337121436 -0.0827260226637496 78 5 0.00594530321046373 841 8063 242687,19353,13426,235661,26415 Wasf2,Rac1,Dync1i1,Dync1li1,Mapk13 mmu00515 Mannose type O-glycan biosynthesis 0.920912301378237 -0.082390468348336 23 1 0.00118906064209275 841 8063 215494 Pomgnt2 ko00515 Mannose type O-glycan biosynthesis 0.920912301378237 -0.082390468348336 23 1 0.00118906064209275 841 8063 215494 Pomgnt2 mmu00900 Terpenoid backbone biosynthesis 0.920912301378237 -0.082390468348336 23 1 0.00118906064209275 841 8063 71365 Pdss2 ko00900 Terpenoid backbone biosynthesis 0.920912301378237 -0.082390468348336 23 1 0.00118906064209275 841 8063 71365 Pdss2 mmu00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.936593340042708 -0.0655060930387723 25 1 0.00118906064209275 841 8063 56176 Pigp M00154 Cytochrome c oxidase 0.936593340042708 -0.0655060930387723 25 1 0.00118906064209275 841 8063 84682 Cox4i2 ko00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 0.936593340042708 -0.0655060930387723 25 1 0.00118906064209275 841 8063 56176 Pigp mmu_M00154 Cytochrome c oxidase 0.936593340042708 -0.0655060930387723 25 1 0.00118906064209275 841 8063 84682 Cox4i2 mmu03013 RNA transport 0.941372701639783 -0.0604161480563301 167 12 0.014268727705113 841 8063 230721,218210,208366,110379,66231,100042807,67724,218268,227720,67676,18458,21335 Pabpc4,Nup153,Rpp40,Sec13,Thoc7,Eif3j2,Pop1,Eif4e1b,Nup214,Rpp21,Pabpc1,Tacc3 ko03013 RNA transport 0.941372701639783 -0.0604161480563301 167 12 0.014268727705113 841 8063 21335,18458,67676,218210,230721,227720,67724,208366,218268,100042807,66231,110379 Tacc3,Pabpc1,Rpp21,Nup153,Pabpc4,Nup214,Pop1,Rpp40,Eif4e1b,Eif3j2,Thoc7,Sec13 M00014 Glucuronate pathway (uronate pathway) 0.943227453129389 -0.0584478238112805 26 1 0.00118906064209275 841 8063 20322 Sord mmu_M00014 Glucuronate pathway (uronate pathway) 0.943227453129389 -0.0584478238112805 26 1 0.00118906064209275 841 8063 20322 Sord mmu05164 Influenza A 0.944214587867595 -0.0574018210130293 168 12 0.014268727705113 841 8063 16160,56637,26415,16451,18708,56489,18815,18550,22333,110157,18751,11651 Il12b,Gsk3b,Mapk13,Jak1,Pik3r1,Ikbke,Plg,Furin,Vdac1,Raf1,Prkcb,Akt1 ko05164 Influenza A 0.944214587867595 -0.0574018210130293 168 12 0.014268727705113 841 8063 56489,18550,18815,110157,18751,22333,11651,16160,26415,56637,18708,16451 Ikbke,Furin,Plg,Raf1,Prkcb,Vdac1,Akt1,Il12b,Mapk13,Gsk3b,Pik3r1,Jak1 ko05134 Legionellosis 0.94988871235034 -0.051410446143928 58 3 0.00356718192627824 841 8063 11783,16160,16415 Apaf1,Il12b,Itgb2l mmu05134 Legionellosis 0.94988871235034 -0.051410446143928 58 3 0.00356718192627824 841 8063 16415,16160,11783 Itgb2l,Il12b,Apaf1 ko00630 Glyoxylate and dicarboxylate metabolism 0.959251560078332 -0.041601923504214 29 1 0.00118906064209275 841 8063 17449 Mdh1 mmu00630 Glyoxylate and dicarboxylate metabolism 0.959251560078332 -0.041601923504214 29 1 0.00118906064209275 841 8063 17449 Mdh1 mmu05416 Viral myocarditis 0.959746296993751 -0.0410863034116161 88 5 0.00594530321046373 841 8063 24052,19353,12389,12487,16415 Sgcd,Rac1,Cav1,Cd28,Itgb2l mmu03020 RNA polymerase 0.963517111218551 -0.0371650318473734 30 1 0.00118906064209275 841 8063 70428 Polr3b ko03020 RNA polymerase 0.963517111218551 -0.0371650318473734 30 1 0.00118906064209275 841 8063 70428 Polr3b ko03008 Ribosome biogenesis in eukaryotes 0.965229684187939 -0.0353891912616297 116 7 0.00832342449464923 841 8063 67724,245474,208366,13000,216987,21453,98956 Pop1,Dkc1,Rpp40,Csnk2a2,Utp6,Tcof1,Nat10 mmu03008 Ribosome biogenesis in eukaryotes 0.965229684187939 -0.0353891912616297 116 7 0.00832342449464923 841 8063 21453,98956,67724,245474,208366,216987,13000 Tcof1,Nat10,Pop1,Dkc1,Rpp40,Utp6,Csnk2a2 ko05322 Systemic lupus erythematosus 0.967301639025796 -0.0332448993612902 142 9 0.0107015457788347 841 8063 26914,97114,15081,68231,12487,97122,12268,12279,319161 H2afy,Hist2h3c2,H3f3b,H2al2a,Cd28,Hist2h4,C4b,C9,Hist1h4n mmu05322 Systemic lupus erythematosus 0.967301639025796 -0.0332448993612902 142 9 0.0107015457788347 841 8063 97114,26914,15081,12268,68231,12487,97122,319161,12279 Hist2h3c2,H2afy,H3f3b,C4b,H2al2a,Cd28,Hist2h4,Hist1h4n,C9 ko05168 Herpes simplex infection 0.969225214194791 -0.0312582749068556 215 15 0.0178359096313912 841 8063 20383,16451,13000,19294,16168,18628,22059,16160,26409,99730,14082,22031,68652,22034,56489 Srsf3,Jak1,Csnk2a2,Nectin2,Il15,Per3,Trp53,Il12b,Map3k7,Taf13,Fadd,Traf3,Tab2,Traf6,Ikbke mmu05168 Herpes simplex infection 0.969225214194791 -0.0312582749068556 215 15 0.0178359096313912 841 8063 19294,16168,22059,18628,16160,26409,20383,16451,13000,68652,22034,56489,99730,14082,22031 Nectin2,Il15,Trp53,Per3,Il12b,Map3k7,Srsf3,Jak1,Csnk2a2,Tab2,Traf6,Ikbke,Taf13,Fadd,Traf3 mmu00980 Metabolism of xenobiotics by cytochrome P450 0.971869737774574 -0.0285334981376739 65 3 0.00356718192627824 841 8063 54486,13078,12409 Hpgds,Cyp1b1,Cbr2 ko00980 Metabolism of xenobiotics by cytochrome P450 0.971869737774574 -0.0285334981376739 65 3 0.00356718192627824 841 8063 54486,13078,12409 Hpgds,Cyp1b1,Cbr2 mmu03040 Spliceosome 0.973527830221713 -0.0268288667801358 133 8 0.00951248513674197 841 8063 20639,20383,20643,66642,14105,67678,67439,71702 Snrpb2,Srsf3,Snrpe,Ctnnbl1,Srsf10,Lsm3,Xab2,Cdc5l ko03040 Spliceosome 0.973527830221713 -0.0268288667801358 133 8 0.00951248513674197 841 8063 14105,67439,67678,71702,20639,20383,20643,66642 Srsf10,Xab2,Lsm3,Cdc5l,Snrpb2,Srsf3,Snrpe,Ctnnbl1 mmu00040 Pentose and glucuronate interconversions 0.976561008429023 -0.0237180539871629 34 1 0.00118906064209275 841 8063 20322 Sord ko00040 Pentose and glucuronate interconversions 0.976561008429023 -0.0237180539871629 34 1 0.00118906064209275 841 8063 20322 Sord mmu03015 mRNA surveillance pathway 0.977319394152806 -0.0229417672084365 96 5 0.00594530321046373 841 8063 18458,14852,230721,226849,18789 Pabpc1,Gspt1,Pabpc4,Ppp2r5a,Papola ko03015 mRNA surveillance pathway 0.977319394152806 -0.0229417672084365 96 5 0.00594530321046373 841 8063 14852,18458,226849,230721,18789 Gspt1,Pabpc1,Ppp2r5a,Pabpc4,Papola mmu04142 Lysosome 0.979335447822085 -0.0208810518083896 124 7 0.00832342449464923 841 8063 252903,14667,16792,56325,17775,20661,15211 Ap1s3,Gm2a,Laptm5,Abcb9,Laptm4a,Sort1,Hexa ko04142 Lysosome 0.979335447822085 -0.0208810518083896 124 7 0.00832342449464923 841 8063 252903,16792,14667,17775,20661,15211,56325 Ap1s3,Laptm5,Gm2a,Laptm4a,Sort1,Hexa,Abcb9 ko00250 Alanine, aspartate and glutamate metabolism 0.983182564770465 -0.0169604540339404 37 1 0.00118906064209275 841 8063 108682 Gpt2 mmu00250 Alanine, aspartate and glutamate metabolism 0.983182564770465 -0.0169604540339404 37 1 0.00118906064209275 841 8063 108682 Gpt2 ko03440 Homologous recombination 0.989199789532552 -0.0108589561002116 41 1 0.00118906064209275 841 8063 74335 Xrcc3 mmu03440 Homologous recombination 0.989199789532552 -0.0108589561002116 41 1 0.00118906064209275 841 8063 74335 Xrcc3 mmu05330 Allograft rejection 0.992823155432084 -0.00720272200344699 64 2 0.00237812128418549 841 8063 16160,12487 Il12b,Cd28 ko04623 Cytosolic DNA-sensing pathway 0.992823155432084 -0.00720272200344699 64 2 0.00237812128418549 841 8063 70428,56489 Polr3b,Ikbke ko05330 Allograft rejection 0.992823155432084 -0.00720272200344699 64 2 0.00237812128418549 841 8063 16160,12487 Il12b,Cd28 mmu04623 Cytosolic DNA-sensing pathway 0.992823155432084 -0.00720272200344699 64 2 0.00237812128418549 841 8063 70428,56489 Polr3b,Ikbke ko00140 Steroid hormone biosynthesis 0.995882041966643 -0.00412646017153251 87 3 0.00356718192627824 841 8063 15484,208665,13078 Hsd11b2,Akr1d1,Cyp1b1 mmu00140 Steroid hormone biosynthesis 0.995882041966643 -0.00412646017153251 87 3 0.00356718192627824 841 8063 208665,15484,13078 Akr1d1,Hsd11b2,Cyp1b1 mmu04940 Type I diabetes mellitus 0.996007688706269 -0.0040003018427272 70 2 0.00237812128418549 841 8063 16160,12487 Il12b,Cd28 ko04940 Type I diabetes mellitus 0.996007688706269 -0.0040003018427272 70 2 0.00237812128418549 841 8063 16160,12487 Il12b,Cd28 mmu03010 Ribosome 0.996522381959582 -0.00348367900993992 177 9 0.0107015457788347 841 8063 56040,67115,20088,114641,67025,57808,68537,11837,64657 Rplp1,Rpl14,Rps24,Rpl31,Rpl11,Rpl35a,Mrpl13,Rplp0,Mrps10 ko03010 Ribosome 0.996522381959582 -0.00348367900993992 177 9 0.0107015457788347 841 8063 67115,20088,56040,57808,67025,68537,11837,64657,114641 Rpl14,Rps24,Rplp1,Rpl35a,Rpl11,Mrpl13,Rplp0,Mrps10,Rpl31 mmu05332 Graft-versus-host disease 0.999246066375604 -0.000754217975280957 65 1 0.00118906064209275 841 8063 12487 Cd28 ko05332 Graft-versus-host disease 0.999246066375604 -0.000754217975280957 65 1 0.00118906064209275 841 8063 12487 Cd28 ko00970 Aminoacyl-tRNA biosynthesis 0.999325343477043 -0.000674884206080392 66 1 0.00118906064209275 841 8063 229487 Gatb mmu00970 Aminoacyl-tRNA biosynthesis 0.999325343477043 -0.000674884206080392 66 1 0.00118906064209275 841 8063 229487 Gatb mmu00982 Drug metabolism - cytochrome P450 0.9993962933541 -0.000603888950132873 67 1 0.00118906064209275 841 8063 54486 Hpgds ko00982 Drug metabolism - cytochrome P450 0.9993962933541 -0.000603888950132873 67 1 0.00118906064209275 841 8063 54486 Hpgds ko05204 Chemical carcinogenesis 0.999600070906124 -0.000400009086844454 93 2 0.00237812128418549 841 8063 13078,54486 Cyp1b1,Hpgds mmu05204 Chemical carcinogenesis 0.999600070906124 -0.000400009086844454 93 2 0.00237812128418549 841 8063 54486,13078 Hpgds,Cyp1b1 ko05320 Autoimmune thyroid disease 0.999841055169178 -0.000158957463890745 79 1 0.00118906064209275 841 8063 12487 Cd28 mmu05320 Autoimmune thyroid disease 0.999841055169178 -0.000158957463890745 79 1 0.00118906064209275 841 8063 12487 Cd28 ko04740 Olfactory transduction 0.999999999878517 -1.21483068562352e-10 1119 13 0.0154577883472057 841 8063 108058,259083,14708,258502,258198,258830,258408,29845,52589,258272,110893,333329,19091 Camk2d,Olfr547,Gng7,Olfr279,Olfr224,Olfr103,Olfr463,Olfr155,Ncald,Olfr1402,Slc8a3,Cngb1,Prkg1 mmu04740 Olfactory transduction 0.999999999878517 -1.21483068562352e-10 1119 13 0.0154577883472057 841 8063 29845,258408,258830,14708,258502,108058,259083,258198,19091,110893,52589,258272,333329 Olfr155,Olfr463,Olfr103,Gng7,Olfr279,Camk2d,Olfr547,Olfr224,Prkg1,Slc8a3,Ncald,Olfr1402,Cngb1