TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols R-MMU-68827 CDT1 association with the CDC6:ORC:origin complex 0.900626280458217 -0.104664890485331 58 4 0.00412796697626419 969 8688 103554,17463,66997,59029 Psme4,Psmd7,Psmd12,Psmd14 R-MMU-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation 0.905932508428854 -0.0987904697218615 34 2 0.00206398348813209 969 8688 18550,14068 Furin,F7 R-MMU-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 0.905932508428854 -0.0987904697218615 34 2 0.00206398348813209 969 8688 67819,14376 Derl1,Ganab R-MMU-392499 Metabolism of proteins 0.906237014188704 -0.0984544020870011 1115 112 0.115583075335397 969 8688 103554,12006,21838,67819,18442,14702,72061,234700,22034,27058,11835,17131,17425,67665,14465,22214,109978,67115,227720,108153,71974,11553,56233,71897,26409,20447,17127,56176,110379,235106,54624,230815,100683,235661,19739,72978,237847,56040,14537,11837,230145,69641,66212,20088,14696,59040,50933,14068,59029,76800,14677,107895,21973,216131,330908,18550,108150,11606,99412,100042807,66997,16011,13191,20442,20742,268890,77038,14852,14376,67561,53625,269181,22031,211446,235505,17380,107260,107995,53618,17126,225131,56505,14693,57808,67128,11647,218210,17342,13000,215494,73582,17463,12945,381694,22059,78754,20450,13426,71954,22194,17918,23956,105522,12418,14799,14678,21825,68404,107607,16005,16010,21802 Psme4,Axin2,Thy1,Derl1,P2ry2,Gng2,Aopep,Nrn1l,Traf6,Srp9,Ar,Smad7,Foxk1,Dctn4,Gata6,Ube2h,Art4,Rpl14,Nup214,Adamts7,Prmt3,Adra2c,Hdac7,Lypd6b,Map3k7,St6galnac3,Smad3,Pigp,Sec13,Ntm,Paf1,Man1c1,Trrap,Dync1li1,Rgs9,Cnih3,Rtn4rl1,Rplp1,Gcnt1,Rplp0,Galnt12,Wdr20,Sec61b,Rps24,Gnb4,Rhot1,Uchl3,F7,Psmd14,Usp42,Gnai1,Mgat5,Top2a,Trappc10,Opcml,Furin,Galnt7,Agt,Golga2,Eif3j2,Psmd12,Igfbp5,Dctn1,St3gal1,Sptbn1,Lsamp,Arfgap2,Gspt1,Ganab,Wdr48,B3gnt2,Mgat4a,Traf3,Exoc3,Cd109,Mme,Otub1,Cdc20,Fut8,Smad2,Wac,Ruvbl1,Gnb2,Rpl35a,Ube2g1,Alpl,Nup153,Mitf,Csnk2a2,Pomgnt2,Camkmt,Psmd7,Dmbt1,B3glct,Trp53,Galnt15,St8sia2,Dync1i1,Suds3,Ube2e1,Myo5a,Neu2,Ankrd28,Cbx4,Gria1,Gnai2,Thbs1,Nrn1,Nod1,Igfals,Igfbp4,Tgfa R-MMU-69186 Lagging Strand Synthesis 0.906323557996422 -0.0983589086628234 20 1 0.00103199174406605 969 8688 19687 Rfc1 R-MMU-159418 Recycling of bile acids and salts 0.906323557996422 -0.0983589086628234 20 1 0.00103199174406605 969 8688 20181 Rxra R-MMU-1834949 Cytosolic sensors of pathogen-associated DNA 0.907763097493978 -0.0967718402663312 59 4 0.00412796697626419 969 8688 70428,20203,69807,11820 Polr3b,S100b,Trim32,App R-MMU-187577 SCF(Skp2)-mediated degradation of p27/p21 0.907763097493978 -0.0967718402663312 59 4 0.00412796697626419 969 8688 17463,59029,66997,12447 Psmd7,Psmd14,Psmd12,Ccne1 R-MMU-1442490 Collagen degradation 0.908304592007339 -0.0961755028802977 47 3 0.00309597523219814 969 8688 18550,17387,17388 Furin,Mmp14,Mmp15 R-MMU-5689603 UCH proteinases 0.911941515091425 -0.0921794191533329 94 7 0.00722394220846233 969 8688 17463,56505,103554,17425,59029,66997,50933 Psmd7,Ruvbl1,Psme4,Foxk1,Psmd14,Psmd12,Uchl3 R-MMU-69002 DNA Replication Pre-Initiation 0.913215965578625 -0.0907828813665074 83 6 0.00619195046439629 969 8688 59029,18974,66997,13555,17463,103554 Psmd14,Pole2,Psmd12,E2f1,Psmd7,Psme4 R-MMU-68874 M/G1 Transition 0.913215965578625 -0.0907828813665074 83 6 0.00619195046439629 969 8688 59029,13555,66997,18974,17463,103554 Psmd14,E2f1,Psmd12,Pole2,Psmd7,Psme4 R-MMU-446219 Synthesis of substrates in N-glycan biosythesis 0.914441361364462 -0.0894419341863195 60 4 0.00412796697626419 969 8688 20442,20450,20447,23956 St3gal1,St8sia2,St6galnac3,Neu2 R-MMU-5685942 HDR through Homologous Recombination (HRR) 0.914441361364462 -0.0894419341863195 60 4 0.00412796697626419 969 8688 19356,19687,15574,74335 Rad17,Rfc1,Hus1,Xrcc3 R-MMU-432720 Lysosome Vesicle Biogenesis 0.914464148484545 -0.0894170153264206 35 2 0.00206398348813209 969 8688 252903,11820 Ap1s3,App R-MMU-5696394 DNA Damage Recognition in GG-NER 0.914464148484545 -0.0894170153264206 35 2 0.00206398348813209 969 8688 56505,56438 Ruvbl1,Rbx1 R-MMU-1592389 Activation of Matrix Metalloproteinases 0.915619834597287 -0.0881540281880725 48 3 0.00309597523219814 969 8688 18550,17387,17389 Furin,Mmp14,Mmp16 R-MMU-189200 Hexose transport 0.915619834597287 -0.0881540281880725 48 3 0.00309597523219814 969 8688 212032,227720,218210 Hk3,Nup214,Nup153 R-MMU-2142753 Arachidonic acid metabolism 0.915903965593614 -0.0878437608592207 72 5 0.00515995872033024 969 8688 230639,19224,54486,13078,21391 Cyp4a29,Ptgs1,Hpgds,Cyp1b1,Tbxas1 R-MMU-69306 DNA Replication 0.916676003763604 -0.0870011911175738 106 8 0.00825593395252838 969 8688 19687,13555,103554,59029,66997,272551,18974,17463 Rfc1,E2f1,Psme4,Psmd14,Psmd12,Gins2,Pole2,Psmd7 R-MMU-156584 Cytosolic sulfonation of small molecules 0.916795693716949 -0.0868706301128098 21 1 0.00103199174406605 969 8688 23972 Papss2 R-MMU-913531 Interferon Signaling 0.920684869169642 -0.0826374628739457 61 4 0.00412796697626419 969 8688 22194,18753,108058,16451 Ube2e1,Prkcd,Camk2d,Jak1 R-MMU-5358346 Hedgehog ligand biogenesis 0.920684869169642 -0.0826374628739457 61 4 0.00412796697626419 969 8688 66997,59029,103554,17463 Psmd12,Psmd14,Psme4,Psmd7 R-MMU-5693607 Processing of DNA double-strand break ends 0.921601065543346 -0.0816428328526522 73 5 0.00515995872033024 969 8688 15574,232314,19356,97122,319161 Hus1,Ppp4r2,Rad17,Hist2h4,Hist1h4n R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs 0.921601065543346 -0.0816428328526522 73 5 0.00515995872033024 969 8688 225870,216131,217835,235633,11651 Rin1,Trappc10,Rin3,Als2cl,Akt1 R-MMU-5696400 Dual Incision in GG-NER 0.92226523917122 -0.0809224187370507 36 2 0.00206398348813209 969 8688 19687,56438 Rfc1,Rbx1 R-MMU-174084 Autodegradation of Cdh1 by Cdh1:APC/C 0.926516806527419 -0.0763230936183127 62 4 0.00412796697626419 969 8688 66997,59029,17463,22194 Psmd12,Psmd14,Psmd7,Ube2e1 R-MMU-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 0.926924082088754 -0.0758836131143567 97 7 0.00722394220846233 969 8688 67184,66916,17993,69875,75406,22227,110842 Ndufa13,Ndufb7,Ndufs4,Ndufa11,Ndufs7,Ucp1,Etfa R-MMU-176187 Activation of ATR in response to replication stress 0.929392409623616 -0.0732242293286547 37 2 0.00206398348813209 969 8688 19356,15574 Rad17,Hus1 R-MMU-196071 Metabolism of steroid hormones 0.929392409623616 -0.0732242293286547 37 2 0.00206398348813209 969 8688 15484,14149 Hsd11b2,Fdxr R-MMU-5685938 HDR through Single Strand Annealing (SSA) 0.929392409623616 -0.0732242293286547 37 2 0.00206398348813209 969 8688 15574,19356 Hus1,Rad17 R-MMU-69239 Synthesis of DNA 0.931398765909121 -0.0710677734195766 98 7 0.00722394220846233 969 8688 17463,103554,19687,59029,66997,18974,272551 Psmd7,Psme4,Rfc1,Psmd14,Psmd12,Pole2,Gins2 R-MMU-69304 Regulation of DNA replication 0.931979500137415 -0.0704444600991649 75 5 0.00515995872033024 969 8688 59029,13555,66997,17463,103554 Psmd14,E2f1,Psmd12,Psmd7,Psme4 R-MMU-427389 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 0.931979500137415 -0.0704444600991649 75 5 0.00515995872033024 969 8688 319161,97114,97122,26914,15081 Hist1h4n,Hist2h3c2,Hist2h4,H2afy,H3f3b R-MMU-73857 RNA Polymerase II Transcription 0.934143932523322 -0.0681247492819668 143 11 0.0113519091847265 969 8688 20643,74197,70122,68776,66231,72290,54624,18789,99730,83602,20383 Snrpe,Gtf2e1,Mllt3,Taf11,Thoc7,Lsm11,Paf1,Papola,Taf13,Gtf2a1,Srsf3 R-MMU-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) 0.934361640832342 -0.0678917199422532 23 1 0.00103199174406605 969 8688 13078 Cyp1b1 R-MMU-425410 Metal ion SLC transporters 0.934361640832342 -0.0678917199422532 23 1 0.00103199174406605 969 8688 338365 Slc41a2 R-MMU-166208 mTORC1-mediated signalling 0.934361640832342 -0.0678917199422532 23 1 0.00103199174406605 969 8688 66096 Lamtor4 R-MMU-191859 snRNP Assembly 0.934485905848228 -0.0677587342246222 51 3 0.00309597523219814 969 8688 218210,227720,20643 Nup153,Nup214,Snrpe R-MMU-194441 Metabolism of non-coding RNA 0.934485905848228 -0.0677587342246222 51 3 0.00309597523219814 969 8688 218210,227720,20643 Nup153,Nup214,Snrpe R-MMU-76046 RNA Polymerase III Transcription Initiation 0.935898759492965 -0.0662479712894434 38 2 0.00206398348813209 969 8688 70428,98488 Polr3b,Gtf3c3 R-MMU-74158 RNA Polymerase III Transcription 0.935898759492965 -0.0662479712894434 38 2 0.00206398348813209 969 8688 70428,98488 Polr3b,Gtf3c3 R-MMU-5693532 DNA Double-Strand Break Repair 0.937418919392673 -0.0646250108588481 133 10 0.0103199174406605 969 8688 19356,97122,319161,14049,15574,74335,19687,232314,14048,22059 Rad17,Hist2h4,Hist1h4n,Eya2,Hus1,Xrcc3,Rfc1,Ppp4r2,Eya1,Trp53 R-MMU-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 0.937758178507676 -0.0642631686423614 88 6 0.00619195046439629 969 8688 20088,11837,57808,67115,56040,14852 Rps24,Rplp0,Rpl35a,Rpl14,Rplp1,Gspt1 R-MMU-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism 0.941701925891963 -0.0600664813455998 24 1 0.00103199174406605 969 8688 93835 Amn R-MMU-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 0.941833941081878 -0.0599263032980811 39 2 0.00206398348813209 969 8688 19356,15574 Rad17,Hus1 R-MMU-166658 Complement cascade 0.941833941081878 -0.0599263032980811 39 2 0.00206398348813209 969 8688 12279,12268 C9,C4b R-MMU-1799339 SRP-dependent cotranslational protein targeting to membrane 0.941852661867788 -0.0599064265458855 89 6 0.00619195046439629 969 8688 56040,27058,11837,20088,57808,67115 Rplp1,Srp9,Rplp0,Rps24,Rpl35a,Rpl14 R-MMU-453274 Mitotic G2-G2/M phases 0.941885842981981 -0.0598711975434412 167 13 0.0134158926728586 969 8688 18472,448987,13555,329251,103554,12234,56438,22059,13191,59029,66997,17463,227613 Pafah1b1,Fbxl7,E2f1,Ppp1r12b,Psme4,Btrc,Rbx1,Trp53,Dctn1,Psmd14,Psmd12,Psmd7,Tubb4b R-MMU-211859 Biological oxidations 0.943106346504461 -0.0585762280471772 231 19 0.0196078431372549 969 8688 320997,20181,19224,14149,242585,72361,230639,11669,54486,232087,18984,234673,228608,21391,232174,13082,71670,13078,23972 Cyp4f39,Rxra,Ptgs1,Fdxr,Slc35d1,Ces2g,Cyp4a29,Aldh2,Hpgds,Mat2a,Por,Ces2e,Smox,Tbxas1,Cyp26b1,Cyp26a1,Acy3,Cyp1b1,Papss2 R-MMU-69242 S Phase 0.944550189124421 -0.0570464551522866 124 9 0.00928792569659443 969 8688 19687,103554,56637,272551,18974,66997,12447,59029,17463 Rfc1,Psme4,Gsk3b,Gins2,Pole2,Psmd12,Ccne1,Psmd14,Psmd7 R-MMU-69656 Cyclin A:Cdk2-associated events at S phase entry 0.946167943171704 -0.0553351959069911 66 4 0.00412796697626419 969 8688 66997,12447,59029,17463 Psmd12,Ccne1,Psmd14,Psmd7 R-MMU-72312 rRNA processing 0.947761578313416 -0.0536523080278534 125 9 0.00928792569659443 969 8688 11837,57316,216987,234374,57808,67115,56040,68979,215193 Rplp0,C1d,Utp6,Ddx49,Rpl35a,Rpl14,Rplp1,Nol11,Utp25 R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 0.947761578313416 -0.0536523080278534 125 9 0.00928792569659443 969 8688 57316,11837,67115,57808,216987,234374,68979,215193,56040 C1d,Rplp0,Rpl14,Rpl35a,Utp6,Ddx49,Nol11,Utp25,Rplp1 R-MMU-8868773 rRNA processing in the nucleus and cytosol 0.947761578313416 -0.0536523080278534 125 9 0.00928792569659443 969 8688 57808,67115,216987,234374,68979,215193,56040,57316,11837 Rpl35a,Rpl14,Utp6,Ddx49,Nol11,Utp25,Rplp1,C1d,Rplp0 R-MMU-901042 Calnexin/calreticulin cycle 0.948222105234888 -0.053166515945859 25 1 0.00103199174406605 969 8688 14376 Ganab R-MMU-191273 Cholesterol biosynthesis 0.948222105234888 -0.053166515945859 25 1 0.00103199174406605 969 8688 235293 Sc5d R-MMU-912497 Meiotic Recombination 0.949327151453346 -0.0520018069513665 91 6 0.00619195046439629 969 8688 17350,15081,26914,97122,97114,319161 Mlh1,H3f3b,H2afy,Hist2h4,Hist2h3c2,Hist1h4n R-MMU-6811440 Retrograde transport at the Trans-Golgi-Network 0.952172836624177 -0.049008709593358 41 2 0.00206398348813209 969 8688 54214,228960 Golga4,Stx16 R-MMU-212165 Epigenetic regulation of gene expression 0.953019769760438 -0.0481196307787411 138 10 0.0103199174406605 969 8688 26914,97122,56637,319161,13435,17913,97114,52463,15081,214133 H2afy,Hist2h4,Gsk3b,Hist1h4n,Dnmt3a,Myo1c,Hist2h3c2,Tet1,H3f3b,Tet2 R-MMU-5693567 HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) 0.953521165409513 -0.0475936565902147 104 7 0.00722394220846233 969 8688 97122,19356,319161,19687,74335,15574,232314 Hist2h4,Rad17,Hist1h4n,Rfc1,Xrcc3,Hus1,Ppp4r2 R-MMU-72187 mRNA 3'-end processing 0.953613169050409 -0.0474971729400545 55 3 0.00309597523219814 969 8688 20383,18789,66231 Srsf3,Papola,Thoc7 R-MMU-156590 Glutathione conjugation 0.954013722466903 -0.0470772235000864 26 1 0.00103199174406605 969 8688 54486 Hpgds R-MMU-912694 Regulation of IFNA signaling 0.954013722466903 -0.0470772235000864 26 1 0.00103199174406605 969 8688 16451 Jak1 R-MMU-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 0.954013722466903 -0.0470772235000864 26 1 0.00103199174406605 969 8688 74335 Xrcc3 R-MMU-2262752 Cellular responses to stress 0.95458128706022 -0.046482477514465 360 31 0.0319917440660475 969 8688 227720,108079,20112,74302,29806,216850,56637,22194,75608,12447,56438,59029,15081,12418,23871,108058,78610,218210,13819,108099,103554,319161,97122,228361,15901,66997,11758,66096,22059,97114,17463 Nup214,Prkaa2,Rps6ka2,Mtmr3,Limd1,Kdm6b,Gsk3b,Ube2e1,Chmp4b,Ccne1,Rbx1,Psmd14,H3f3b,Cbx4,Ets1,Camk2d,Uvrag,Nup153,Epas1,Prkag2,Psme4,Hist1h4n,Hist2h4,Ambra1,Id1,Psmd12,Prdx6,Lamtor4,Trp53,Hist2h3c2,Psmd7 R-MMU-983169 Class I MHC mediated antigen processing & presentation 0.955080350341529 -0.0459598055574052 215 17 0.0175438596491228 969 8688 56438,59029,104184,81018,269514,110379,20437,17463,66997,16419,103554,380928,12234,218215,387524,448987,244421 Rbx1,Psmd14,Blmh,Rnf114,Fbxl4,Sec13,Siah1a,Psmd7,Psmd12,Itgb5,Psme4,Lmo7,Btrc,Rnf144b,Znrf2,Fbxl7,Lonrf1 R-MMU-3108232 SUMO E3 ligases SUMOylate target proteins 0.955926329630832 -0.0450744299557069 93 6 0.00619195046439629 969 8688 21973,56233,12418,17342,218210,227720 Top2a,Hdac7,Cbx4,Mitf,Nup153,Nup214 R-MMU-211000 Gene Silencing by RNA 0.956512142808718 -0.0444617951393179 105 7 0.00722394220846233 969 8688 319161,213988,97114,97122,227720,15081,218210 Hist1h4n,Tnrc6b,Hist2h3c2,Hist2h4,Nup214,H3f3b,Nup153 R-MMU-5656169 Termination of translesion DNA synthesis 0.959158112081745 -0.0416993458619282 27 1 0.00103199174406605 969 8688 19687 Rfc1 R-MMU-69052 Switching of origins to a post-replicative state 0.960896754095582 -0.0398883116881965 70 4 0.00412796697626419 969 8688 17463,103554,59029,66997 Psmd7,Psme4,Psmd14,Psmd12 R-MMU-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 0.960896754095582 -0.0398883116881965 70 4 0.00412796697626419 969 8688 23956,20447,20450,20442 Neu2,St6galnac3,St8sia2,St3gal1 R-MMU-68949 Orc1 removal from chromatin 0.960896754095582 -0.0398883116881965 70 4 0.00412796697626419 969 8688 103554,17463,66997,59029 Psme4,Psmd7,Psmd12,Psmd14 R-MMU-3371453 Regulation of HSF1-mediated heat shock response 0.961086946714506 -0.0396903988552571 57 3 0.00309597523219814 969 8688 227720,218210,56637 Nup214,Nup153,Gsk3b R-MMU-72689 Formation of a pool of free 40S subunits 0.961737812158281 -0.039013409997453 95 6 0.00619195046439629 969 8688 67115,57808,20088,11837,56040,100042807 Rpl14,Rpl35a,Rps24,Rplp0,Rplp1,Eif3j2 R-MMU-1640170 Cell Cycle 0.96278454623296 -0.0379256240610315 596 54 0.0557275541795666 969 8688 22194,208628,56637,19356,13555,70315,22630,18472,72415,217718,15574,71175,66311,12447,15081,59029,56438,229776,66578,97122,56505,329251,19687,13000,67121,218210,110379,226849,17463,12617,11651,22059,227720,22367,18974,272551,66977,107995,319161,12234,103554,26914,21973,245474,18751,14245,448987,227613,67956,97114,99412,66997,13191,17350 Ube2e1,Kntc1,Gsk3b,Rad17,E2f1,Hdac8,Ywhaq,Pafah1b1,Sgo1,Nek9,Hus1,Nipbl,Cenpw,Ccne1,H3f3b,Psmd14,Rbx1,Cdc14a,Mis18a,Hist2h4,Ruvbl1,Ppp1r12b,Rfc1,Csnk2a2,Mastl,Nup153,Sec13,Ppp2r5a,Psmd7,Cenpc1,Akt1,Trp53,Nup214,Vrk1,Pole2,Gins2,Nuf2,Cdc20,Hist1h4n,Btrc,Psme4,H2afy,Top2a,Dkc1,Prkcb,Lpin1,Fbxl7,Tubb4b,Kmt5a,Hist2h3c2,Golga2,Psmd12,Dctn1,Mlh1 R-MMU-909733 Interferon alpha/beta signaling 0.963727537028229 -0.0369466622587428 28 1 0.00103199174406605 969 8688 16451 Jak1 R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 0.963944588793532 -0.0367214665282941 71 4 0.00412796697626419 969 8688 66231,20383,227720,218210 Thoc7,Srsf3,Nup214,Nup153 R-MMU-72202 Transport of Mature Transcript to Cytoplasm 0.963944588793532 -0.0367214665282941 71 4 0.00412796697626419 969 8688 66231,20383,227720,218210 Thoc7,Srsf3,Nup214,Nup153 R-MMU-69275 G2/M Transition 0.964125779711006 -0.0365335160043226 165 12 0.0123839009287926 969 8688 329251,448987,18472,103554,12234,66997,56438,13191,59029,22059,227613,17463 Ppp1r12b,Fbxl7,Pafah1b1,Psme4,Btrc,Psmd12,Rbx1,Dctn1,Psmd14,Trp53,Tubb4b,Psmd7 R-MMU-73893 DNA Damage Bypass 0.964453798438032 -0.0361933498697165 44 2 0.00206398348813209 969 8688 56438,19687 Rbx1,Rfc1 R-MMU-5250913 Positive epigenetic regulation of rRNA expression 0.964473502385873 -0.0361729199158941 108 7 0.00722394220846233 969 8688 15081,97122,26914,56637,17913,319161,97114 H3f3b,Hist2h4,H2afy,Gsk3b,Myo1c,Hist1h4n,Hist2h3c2 R-MMU-2565942 Regulation of PLK1 Activity at G2/M Transition 0.965015938461393 -0.0356106612392443 84 5 0.00515995872033024 969 8688 18472,13191,329251,227613,12234 Pafah1b1,Dctn1,Ppp1r12b,Tubb4b,Btrc R-MMU-69300 Removal of licensing factors from origins 0.966770507794093 -0.0337941355890373 72 4 0.00412796697626419 969 8688 59029,66997,17463,103554 Psmd14,Psmd12,Psmd7,Psme4 R-MMU-6807505 RNA polymerase II transcribes snRNA genes 0.966770507794093 -0.0337941355890373 72 4 0.00412796697626419 969 8688 99730,83602,74197,68776 Taf13,Gtf2a1,Gtf2e1,Taf11 R-MMU-5693538 Homology Directed Repair 0.966817796818548 -0.0337452223593171 109 7 0.00722394220846233 969 8688 232314,19687,74335,15574,319161,97122,19356 Ppp4r2,Rfc1,Xrcc3,Hus1,Hist1h4n,Hist2h4,Rad17 R-MMU-69620 Cell Cycle Checkpoints 0.9677373492232 -0.032794561970247 178 13 0.0134158926728586 969 8688 15574,22630,103554,319161,19356,97122,22194,66997,12447,22059,107995,59029,17463 Hus1,Ywhaq,Psme4,Hist1h4n,Rad17,Hist2h4,Ube2e1,Psmd12,Ccne1,Trp53,Cdc20,Psmd14,Psmd7 R-MMU-69206 G1/S Transition 0.969020463133847 -0.0314695495291604 110 7 0.00722394220846233 969 8688 59029,18974,11651,13555,66997,12447,17463 Psmd14,Pole2,Akt1,E2f1,Psmd12,Ccne1,Psmd7 R-MMU-3371556 Cellular response to heat stress 0.969389026178026 -0.0310892758556636 73 4 0.00412796697626419 969 8688 108058,56637,227720,218210 Camk2d,Gsk3b,Nup214,Nup153 R-MMU-3108214 SUMOylation of DNA damage response and repair proteins 0.969389026178026 -0.0310892758556636 73 4 0.00412796697626419 969 8688 12418,56233,227720,218210 Cbx4,Hdac7,Nup214,Nup153 R-MMU-3700989 Transcriptional Regulation by TP53 0.969919544994198 -0.0305421542296456 266 21 0.021671826625387 969 8688 231464,12905,77976,13000,108099,67956,11651,66096,22059,99730,57748,19356,319801,108079,22630,15258,15574,20393,69260,12447,68776 Cnot6l,Cradd,Nuak1,Csnk2a2,Prkag2,Kmt5a,Akt1,Lamtor4,Trp53,Taf13,Jmy,Rad17,Tigar,Prkaa2,Ywhaq,Hipk2,Hus1,Sgk1,Ing2,Ccne1,Taf11 R-MMU-2990846 SUMOylation 0.971317468734179 -0.0291019138347458 99 6 0.00619195046439629 969 8688 218210,17342,227720,21973,12418,56233 Nup153,Mitf,Nup214,Top2a,Cbx4,Hdac7 R-MMU-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 0.971391139156528 -0.0290260708368976 30 1 0.00103199174406605 969 8688 70428 Polr3b R-MMU-69481 G2/M Checkpoints 0.972647041096728 -0.0277340158477779 147 10 0.0103199174406605 969 8688 59029,22059,66997,17463,22630,15574,97122,19356,319161,103554 Psmd14,Trp53,Psmd12,Psmd7,Ywhaq,Hus1,Hist2h4,Rad17,Hist1h4n,Psme4 R-MMU-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 0.972767812788863 -0.0276098555001287 61 3 0.00309597523219814 969 8688 19687,56438,67439 Rfc1,Rbx1,Xab2 R-MMU-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 0.973672752458491 -0.0266800148967349 47 2 0.00206398348813209 969 8688 387347,54393 Tas2r118,Gabbr1 R-MMU-73894 DNA Repair 0.973890861457806 -0.0264560335092534 269 21 0.021671826625387 969 8688 19687,56505,97122,18294,319161,17350,330554,22059,74335,15574,208836,232314,14048,268420,71885,19356,67439,101831,14049,56438,14087 Rfc1,Ruvbl1,Hist2h4,Ogg1,Hist1h4n,Mlh1,Fan1,Trp53,Xrcc3,Hus1,Fanci,Ppp4r2,Eya1,Alkbh5,Faap100,Rad17,Xab2,Faap24,Eya2,Rbx1,Fanca R-MMU-68962 Activation of the pre-replicative complex 0.974593031754825 -0.0257352984496922 31 1 0.00103199174406605 969 8688 18974 Pole2 R-MMU-390522 Striated Muscle Contraction 0.974593031754825 -0.0257352984496922 31 1 0.00103199174406605 969 8688 233199 Mybpc2 R-MMU-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 0.974593031754825 -0.0257352984496922 31 1 0.00103199174406605 969 8688 74335 Xrcc3 R-MMU-6782135 Dual incision in TC-NER 0.975119558875567 -0.0251951910142964 62 3 0.00309597523219814 969 8688 19687,56438,67439 Rfc1,Rbx1,Xab2 R-MMU-72695 Formation of the ternary complex, and subsequently, the 43S complex 0.976196792372534 -0.024091081364714 48 2 0.00206398348813209 969 8688 20088,100042807 Rps24,Eif3j2 R-MMU-5693571 Nonhomologous End-Joining (NHEJ) 0.976196792372534 -0.024091081364714 48 2 0.00206398348813209 969 8688 97122,319161 Hist2h4,Hist1h4n R-MMU-504046 RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription 0.976559091424249 -0.0237200170049767 114 7 0.00722394220846233 969 8688 98488,15081,70428,97114,208595,319161,97122 Gtf3c3,H3f3b,Polr3b,Hist2h3c2,Mterf1b,Hist1h4n,Hist2h4 R-MMU-5693537 Resolution of D-Loop Structures 0.977436898254605 -0.0228215434215676 32 1 0.00103199174406605 969 8688 74335 Xrcc3 R-MMU-156580 Phase II conjugation 0.978052792423999 -0.0221916304205475 77 4 0.00412796697626419 969 8688 23972,54486,242585,232087 Papss2,Hpgds,Slc35d1,Mat2a R-MMU-573389 NoRC negatively regulates rRNA expression 0.979678713631007 -0.0205306043035276 91 5 0.00515995872033024 969 8688 15081,97114,319161,26914,97122 H3f3b,Hist2h3c2,Hist1h4n,H2afy,Hist2h4 R-MMU-156827 L13a-mediated translational silencing of Ceruloplasmin expression 0.980182172685026 -0.0200168340980923 104 6 0.00619195046439629 969 8688 11837,20088,67115,57808,56040,100042807 Rplp0,Rps24,Rpl14,Rpl35a,Rplp1,Eif3j2 R-MMU-427413 NoRC negatively regulates rRNA expression 0.981227459397499 -0.0189509814640141 92 5 0.00515995872033024 969 8688 26914,97122,319161,97114,15081 H2afy,Hist2h4,Hist1h4n,Hist2h3c2,H3f3b R-MMU-72766 Translation 0.982144991644362 -0.018016332194417 130 8 0.00825593395252838 969 8688 57808,67115,14852,27058,56040,20088,11837,100042807 Rpl35a,Rpl14,Gspt1,Srp9,Rplp1,Rps24,Rplp0,Eif3j2 R-MMU-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 0.982206075533795 -0.01795413975797 34 1 0.00103199174406605 969 8688 19687 Rfc1 R-MMU-69231 Cyclin D associated events in G1 0.982206075533795 -0.01795413975797 34 1 0.00103199174406605 969 8688 13555 E2f1 R-MMU-5689901 Metalloprotease DUBs 0.982206075533795 -0.01795413975797 34 1 0.00103199174406605 969 8688 59029 Psmd14 R-MMU-69236 G1 Phase 0.982206075533795 -0.01795413975797 34 1 0.00103199174406605 969 8688 13555 E2f1 R-MMU-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 0.98295399279 -0.0171929627888545 106 6 0.00619195046439629 969 8688 100042807,56040,20088,11837,57808,67115 Eif3j2,Rplp1,Rps24,Rplp0,Rpl35a,Rpl14 R-MMU-73854 RNA Polymerase I Promoter Clearance 0.982974059109751 -0.0171725486951322 80 4 0.00412796697626419 969 8688 97114,319161,97122,15081 Hist2h3c2,Hist1h4n,Hist2h4,H3f3b R-MMU-3299685 Detoxification of Reactive Oxygen Species 0.984198485163094 -0.0159276897070079 35 1 0.00103199174406605 969 8688 11758 Prdx6 R-MMU-380284 Loss of proteins required for interphase microtubule organization from the centrosome 0.984254801014845 -0.0158704713293483 67 3 0.00309597523219814 969 8688 227613,13191,18472 Tubb4b,Dctn1,Pafah1b1 R-MMU-380259 Loss of Nlp from mitotic centrosomes 0.984254801014845 -0.0158704713293483 67 3 0.00309597523219814 969 8688 18472,13191,227613 Pafah1b1,Dctn1,Tubb4b R-MMU-73864 RNA Polymerase I Transcription 0.984368016457975 -0.0157554513852031 81 4 0.00412796697626419 969 8688 97122,97114,319161,15081 Hist2h4,Hist2h3c2,Hist1h4n,H3f3b R-MMU-453279 Mitotic G1-G1/S phases 0.984457328344709 -0.0156647253215318 132 8 0.00825593395252838 969 8688 21973,13555,17463,59029,11651,18974,12447,66997 Top2a,E2f1,Psmd7,Psmd14,Akt1,Pole2,Ccne1,Psmd12 R-MMU-72172 mRNA Splicing 0.985166188238032 -0.0149449330181196 180 12 0.0123839009287926 969 8688 74326,66642,80744,20643,67225,18789,67678,59013,20383,67439,20639,71702 Hnrnpr,Ctnnbl1,Cwc22,Snrpe,Rnpc3,Papola,Lsm3,Hnrnph1,Srsf3,Xab2,Snrpb2,Cdc5l R-MMU-927802 Nonsense-Mediated Decay (NMD) 0.985360362203436 -0.0147478547640972 108 6 0.00619195046439629 969 8688 20088,11837,67115,57808,56040,14852 Rps24,Rplp0,Rpl14,Rpl35a,Rplp1,Gspt1 R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 0.985360362203436 -0.0147478547640972 108 6 0.00619195046439629 969 8688 14852,56040,57808,67115,11837,20088 Gspt1,Rplp1,Rpl35a,Rpl14,Rplp0,Rps24 R-MMU-5389840 Mitochondrial translation elongation 0.986837776965457 -0.0132496127679765 83 4 0.00412796697626419 969 8688 64657,68537,66230,60441 Mrps10,Mrpl13,Mrps28,Mrpl38 R-MMU-72649 Translation initiation complex formation 0.987083891116089 -0.0130002470956836 54 2 0.00206398348813209 969 8688 20088,100042807 Rps24,Eif3j2 R-MMU-6809371 Formation of the cornified envelope 0.987083891116089 -0.0130002470956836 54 2 0.00206398348813209 969 8688 18550,71529 Furin,Kazn R-MMU-6781823 Formation of TC-NER Pre-Incision Complex 0.987083891116089 -0.0130002470956836 54 2 0.00206398348813209 969 8688 67439,56438 Xab2,Rbx1 R-MMU-72163 mRNA Splicing - Major Pathway 0.987434734453854 -0.0126448760833121 171 11 0.0113519091847265 969 8688 71702,20639,67439,20383,59013,67678,18789,20643,80744,66642,74326 Cdc5l,Snrpb2,Xab2,Srsf3,Hnrnph1,Lsm3,Papola,Snrpe,Cwc22,Ctnnbl1,Hnrnpr R-MMU-8854518 AURKA Activation by TPX2 0.98808747799814 -0.0119840446697991 70 3 0.00309597523219814 969 8688 18472,13191,227613 Pafah1b1,Dctn1,Tubb4b R-MMU-72165 mRNA Splicing - Minor Pathway 0.988346937241648 -0.0117214918190715 55 2 0.00206398348813209 969 8688 67225,20643 Rnpc3,Snrpe R-MMU-72702 Ribosomal scanning and start codon recognition 0.988346937241648 -0.0117214918190715 55 2 0.00206398348813209 969 8688 20088,100042807 Rps24,Eif3j2 R-MMU-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 0.988346937241648 -0.0117214918190715 55 2 0.00206398348813209 969 8688 20088,100042807 Rps24,Eif3j2 R-MMU-5419276 Mitochondrial translation termination 0.988933465510276 -0.0111282241317828 85 4 0.00412796697626419 969 8688 66230,68537,64657,60441 Mrps28,Mrpl13,Mrps10,Mrpl38 R-MMU-168249 Innate Immune System 0.989063340938338 -0.0109969039720886 1185 110 0.113519091847265 969 8688 18708,74012,14180,20742,18479,432530,212032,212114,20112,16498,231507,14083,12652,69601,20203,242687,13429,17380,330662,11974,12234,20418,11820,18590,216134,70428,12048,11783,26410,227613,72157,100042150,66997,12268,16451,18754,66290,70450,66589,26458,26415,18015,53378,19258,384783,269116,380924,381925,353204,110078,56438,107607,12283,18641,110157,19353,11515,17463,11625,16415,235584,18600,240672,224129,68652,100037283,12487,17079,14172,12279,14184,14173,18405,383295,103554,69807,22034,74287,71902,29875,15461,14186,11674,235661,21897,93834,16337,70152,108058,17973,103967,56489,15926,108723,14667,59029,231474,18753,26409,68682,67603,26364,226849,67245,19262,11651,19055,14183,11758,57257 Pik3r1,Rap2b,Fgf9,Sptbn1,Pak1,Adcy1,Hk3,Nhlrc3,Rps6ka2,Kcnab2,Plac8,Ptk2,Chga,Dab2ip,S100b,Wasf2,Dnm1,Mme,Dock1,Atp6v0e,Btrc,Shc3,App,Pdgfa,Pdxk,Polr3b,Bcl2l1,Apaf1,Map3k8,Tubb4b,Pgm2,Nrg2,Psmd12,C4b,Jak1,Prkce,Atp6v1g1,Unc13d,Ube2v1,Slc27a2,Mapk13,Nf1,Sdcbp,Ptpn4,Irs2,Nfasc,Olfm4,Plpp4,Aldoart1,Pygb,Rbx1,Nod1,Cab39,Pfkl,Raf1,Rac1,Adcy9,Psmd7,Ahsg,Itgb2l,Dusp7,Padi2,Dusp5,Adcy5,Tab2,Rnaset2a,Cd28,Cd180,Fgf18,C9,Fgfr3,Fgf2,Orm1,Ypel5,Psme4,Trim32,Traf6,Kcmf1,Cand1,Iqgap1,Hras,Fgfr4,Aldoa,Dync1li1,Tlr1,Peli2,Insr,Mettl7a1,Camk2d,Nck1,Dnm3,Ikbke,Idh1,Card11,Gm2a,Psmd14,Paqr3,Prkcd,Map3k7,Slc44a2,Dusp6,Adgre5,Ppp2r5a,Peli1,Ptpra,Akt1,Ppp3ca,Fgfr2,Prdx6,Vav3 R-MMU-72613 Eukaryotic Translation Initiation 0.989249034903216 -0.0108091743013944 112 6 0.00619195046439629 969 8688 100042807,56040,11837,20088,57808,67115 Eif3j2,Rplp1,Rplp0,Rps24,Rpl35a,Rpl14 R-MMU-72737 Cap-dependent Translation Initiation 0.989249034903216 -0.0108091743013944 112 6 0.00619195046439629 969 8688 100042807,56040,11837,20088,67115,57808 Eif3j2,Rplp1,Rplp0,Rps24,Rpl14,Rpl35a R-MMU-1236975 Antigen processing-Cross presentation 0.989336896443066 -0.0107203618434513 99 5 0.00515995872033024 969 8688 16419,66997,59029,103554,17463 Itgb5,Psmd12,Psmd14,Psme4,Psmd7 R-MMU-372790 Signaling by GPCR 0.989406447361213 -0.0106500637743321 1331 125 0.128998968008256 969 8688 14677,19220,258198,23945,20418,230972,11820,18590,52250,104418,11606,100042150,66997,15550,258830,14180,18619,18708,18755,432530,20742,20112,12778,14083,69601,68338,14682,109648,12776,12922,29863,51801,22065,50501,387347,78134,52666,13615,208188,14693,19353,110157,269608,15552,14709,11515,11549,17463,171469,277360,212541,15199,235584,226278,18754,213498,16451,14527,15465,23984,14678,18015,67839,384783,56438,380698,21844,103554,14702,17200,18442,18430,56696,50780,54393,14773,239766,12775,320127,15461,240672,224129,207212,14708,12061,545156,58182,14172,14173,237362,14184,100043507,258408,11553,233571,18753,243407,231474,26364,235611,67603,226849,109934,19262,14183,11651,14710,57257,73341,16440,218461,14186,11516,16801,54199,11535,108058,14696,14675,71111,14683,20315,11548,242093,59029 Gnai1,Ptgfr,Olfr224,Mgll,Shc3,Arhgef16,App,Pdgfa,Reep1,Dgkz,Agt,Nrg2,Psmd12,Htr1a,Olfr103,Fgf9,Penk,Pik3r1,Prkch,Adcy1,Sptbn1,Rps6ka2,Ackr3,Ptk2,Dab2ip,Golt1a,Gnaq,Npy,Ccr8,Crhr2,Pde7b,Ramp1,Trpc3,Prok2,Tas2r118,Lpar4,Arhgef25,Edn2,Ghsr,Gnb2,Rac1,Raf1,Plekhg5,Htr1d,Gng8,Adcy9,Adra1a,Psmd7,Gpr37l1,Prex1,Rho,Hebp1,Dusp7,Prlhr,Prkce,Arhgef11,Jak1,Gcgr,Hrh1,Pde10a,Gnai2,Nf1,Gpsm1,Irs2,Rbx1,Obscn,Tiam1,Psme4,Gng2,Mc2r,P2ry2,Oxtr,Gpr132,Rgs3,Gabbr1,Grk5,Rtp1,Ccr7,Dgki,Hras,Dusp5,Adcy5,Arhgef17,Gng7,Bdkrb1,Kalrn,Prokr1,Fgf18,Fgf2,Npffr1,Fgfr3,Gng5-ps,Olfr463,Adra2c,P2ry6,Prkcd,Qrfprl,Paqr3,Adgre5,Plxnb1,Dusp6,Ppp2r5a,Abr,Ptpra,Fgfr2,Akt1,Gngt2,Vav3,Arhgef6,Itpr3,Pde8b,Fgfr4,Adcyap1,Arhgef1,Ccrl2,Adm,Camk2d,Gnb4,Gna14,Gpr39,Gnas,Cxcl12,Adra1b,Rxfp4,Psmd14 R-MMU-5368287 Mitochondrial translation 0.989858007241826 -0.0101937731685995 86 4 0.00412796697626419 969 8688 60441,68537,64657,66230 Mrpl38,Mrpl13,Mrps10,Mrps28 R-MMU-5250941 Negative epigenetic regulation of rRNA expression 0.990178843227311 -0.00986970244414134 100 5 0.00515995872033024 969 8688 26914,97122,97114,319161,15081 H2afy,Hist2h4,Hist2h3c2,Hist1h4n,H3f3b R-MMU-168256 Immune System 0.990418721236104 -0.00962747452841572 1698 163 0.168214654282766 969 8688 16419,252903,17463,11625,19353,110157,11515,16878,19091,380924,12283,56438,110078,53378,19258,66589,26415,16169,56508,16451,16168,26410,11783,216134,18590,70428,244421,448987,12234,380928,20418,11820,17380,69601,22031,20203,242687,212114,20112,14083,14180,74012,432530,212032,18414,11651,26364,16569,67603,18383,16068,68682,56489,19116,14667,108723,59029,15926,70152,13608,16337,93834,213208,104184,16440,216233,235661,29875,71902,19294,20850,22034,383295,218215,69807,12803,20586,240672,18600,17079,12487,16415,235584,16160,21936,387524,381925,353204,269116,384783,18641,16880,107607,18015,81018,26458,18754,13426,22194,66290,70450,66997,100042150,13191,12268,227613,97114,12048,72157,16190,20437,16579,76399,12143,11974,330662,13800,21940,13429,12652,16498,94212,231507,18708,20742,18479,14183,19055,11758,57257,110379,67245,226849,19262,18753,231474,26409,103967,243864,108058,110351,17973,21897,269514,11674,14186,107746,668303,76527,15461,67665,18751,74287,103554,18405,12279,14172,14184,15985,14173,68652,224129,100037283 Itgb5,Ap1s3,Psmd7,Ahsg,Rac1,Raf1,Adcy9,Lif,Prkg1,Olfm4,Cab39,Rbx1,Pygb,Sdcbp,Ptpn4,Ube2v1,Mapk13,Il15ra,Rapgef4,Jak1,Il15,Map3k8,Apaf1,Pdxk,Pdgfa,Polr3b,Lonrf1,Fbxl7,Btrc,Lmo7,Shc3,App,Mme,Dab2ip,Traf3,S100b,Wasf2,Nhlrc3,Rps6ka2,Ptk2,Fgf9,Rap2b,Adcy1,Hk3,Osmr,Akt1,Adgre5,Kif3b,Dusp6,Tnfrsf11b,Il18bp,Slc44a2,Ikbke,Prlr,Gm2a,Card11,Psmd14,Idh1,Mettl7a1,Edar,Insr,Peli2,Il20rb,Blmh,Itpr3,Socs2,Dync1li1,Iqgap1,Cand1,Nectin2,Stat5a,Traf6,Ypel5,Rnf144b,Trim32,Cntf,Smarca4,Dusp5,Padi2,Cd180,Cd28,Itgb2l,Dusp7,Il12b,Tnfrsf18,Znrf2,Plpp4,Aldoart1,Nfasc,Irs2,Pfkl,Lifr,Nod1,Nf1,Rnf114,Slc27a2,Prkce,Dync1i1,Ube2e1,Atp6v1g1,Unc13d,Psmd12,Nrg2,Dctn1,C4b,Tubb4b,Hist2h3c2,Bcl2l1,Pgm2,Il4ra,Siah1a,Kifap3,Il31,Blk,Atp6v0e,Dock1,Enah,Cd27,Dnm1,Chga,Kcnab2,Pag1,Plac8,Pik3r1,Sptbn1,Pak1,Fgfr2,Ppp3ca,Prdx6,Vav3,Sec13,Peli1,Ppp2r5a,Ptpra,Prkcd,Paqr3,Map3k7,Dnm3,Mill2,Camk2d,Rap1gap,Nck1,Tlr1,Fbxl4,Aldoa,Fgfr4,Rapgef1,Kif26a,Il34,Hras,Dctn4,Prkcb,Kcmf1,Psme4,Orm1,C9,Fgf18,Fgfr3,Cd79b,Fgf2,Tab2,Adcy5,Rnaset2a R-MMU-75955 RNA Polymerase II Transcription Elongation 0.991455563351645 -0.00858114962456257 58 2 0.00206398348813209 969 8688 70122,54624 Mllt3,Paf1 R-MMU-112382 Formation of RNA Pol II elongation complex 0.991455563351645 -0.00858114962456257 58 2 0.00206398348813209 969 8688 70122,54624 Mllt3,Paf1 R-MMU-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 0.991825748196978 -0.00820784418627084 74 3 0.00309597523219814 969 8688 67439,19687,56438 Xab2,Rfc1,Rbx1 R-MMU-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 0.991825748196978 -0.00820784418627084 74 3 0.00309597523219814 969 8688 56505,19687,56438 Ruvbl1,Rfc1,Rbx1 R-MMU-5696395 Formation of Incision Complex in GG-NER 0.992253105262845 -0.00777705780726051 41 1 0.00103199174406605 969 8688 56438 Rbx1 R-MMU-380270 Recruitment of mitotic centrosome proteins and complexes 0.992566067837135 -0.00746170154596971 75 3 0.00309597523219814 969 8688 227613,18472,13191 Tubb4b,Pafah1b1,Dctn1 R-MMU-380287 Centrosome maturation 0.992566067837135 -0.00746170154596971 75 3 0.00309597523219814 969 8688 227613,13191,18472 Tubb4b,Dctn1,Pafah1b1 R-MMU-6803157 Antimicrobial peptides 0.993060797568401 -0.00696339065974722 60 2 0.00206398348813209 969 8688 21897,12652 Tlr1,Chga R-MMU-1221633 Meiotic Synapsis 0.994046390969989 -0.00597140241865547 106 5 0.00515995872033024 969 8688 15081,319161,97114,97122,26914 H3f3b,Hist1h4n,Hist2h3c2,Hist2h4,H2afy R-MMU-1221632 Meiotic synapsis 0.994046390969989 -0.00597140241865547 106 5 0.00515995872033024 969 8688 319161,97114,97122,26914,15081 Hist1h4n,Hist2h3c2,Hist2h4,H2afy,H3f3b R-MMU-72203 Processing of Capped Intron-Containing Pre-mRNA 0.994500722459932 -0.00551445423293726 231 15 0.0154798761609907 969 8688 66231,74326,80744,66642,67225,20643,67678,67439,59013,20383,18789,20639,218210,71702,227720 Thoc7,Hnrnpr,Cwc22,Ctnnbl1,Rnpc3,Snrpe,Lsm3,Xab2,Hnrnph1,Srsf3,Papola,Snrpb2,Nup153,Cdc5l,Nup214 R-MMU-5620912 Anchoring of the basal body to the plasma membrane 0.994543871678655 -0.00547106735377263 93 4 0.00412796697626419 969 8688 18472,13191,382090,227613 Pafah1b1,Dctn1,Cep162,Tubb4b R-MMU-1500620 Meiosis 0.995525901493242 -0.00448413723952602 123 6 0.00619195046439629 969 8688 319161,97114,26914,97122,15081,17350 Hist1h4n,Hist2h3c2,H2afy,Hist2h4,H3f3b,Mlh1 R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 0.997007657837571 -0.00299682816958545 49 1 0.00103199174406605 969 8688 110379 Sec13 R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis 0.997167246635532 -0.00283677320354979 85 3 0.00309597523219814 969 8688 22418,22042,73094 Wnt5a,Tfrc,Sgip1 R-MMU-8856828 Clathrin-mediated endocytosis 0.997247819601904 -0.00275597460973675 115 5 0.00515995872033024 969 8688 22418,22042,14269,73094,20975 Wnt5a,Tfrc,Fnbp1,Sgip1,Synj2 R-MMU-5696398 Nucleotide Excision Repair 0.997805634096201 -0.00219677705259948 103 4 0.00412796697626419 969 8688 67439,56505,56438,19687 Xab2,Ruvbl1,Rbx1,Rfc1 R-MMU-6798695 Neutrophil degranulation 0.999355649041526 -0.000644558641771785 561 41 0.0423116615067079 969 8688 16498,212114,231507,100037283,18600,74012,212032,17380,18405,74287,216134,383295,29875,66997,227613,71902,11783,72157,26458,11674,235661,70450,353204,380924,269116,14667,18641,59029,12283,110078,15926,70152,53378,19353,26364,18753,68682,16415,11758,17463,11625 Kcnab2,Nhlrc3,Plac8,Rnaset2a,Padi2,Rap2b,Hk3,Mme,Orm1,Kcmf1,Pdxk,Ypel5,Iqgap1,Psmd12,Tubb4b,Cand1,Apaf1,Pgm2,Slc27a2,Aldoa,Dync1li1,Unc13d,Aldoart1,Olfm4,Nfasc,Gm2a,Pfkl,Psmd14,Cab39,Pygb,Idh1,Mettl7a1,Sdcbp,Rac1,Adgre5,Prkcd,Slc44a2,Itgb2l,Prdx6,Psmd7,Ahsg R-MMU-74160 Gene Expression 0.999702023333228 -0.000298021070640389 1163 97 0.100103199174407 969 8688 66231,19411,72290,17913,98488,106931,68106,319161,103554,27058,11835,12905,68979,17131,20393,67225,52463,15507,234374,67115,20383,108079,227720,21676,215193,80744,57316,54624,11651,66096,216987,18789,18753,97122,67678,17127,231464,26381,71702,70640,20088,11837,14815,12447,20643,59029,15081,12192,18128,56637,56040,15258,97114,67956,19883,80707,270118,66997,20181,100042807,213988,26914,20602,21388,70428,66642,69260,641340,74197,99730,57748,59013,83602,14852,208595,17463,22337,22059,17126,21679,57808,77976,108099,13000,218210,19401,74326,70122,214133,68776,67439,19356,319801,22630,20639,15574,13435 Thoc7,Rarg,Lsm11,Myo1c,Gtf3c3,Kctd1,Nt5c3b,Hist1h4n,Psme4,Srp9,Ar,Cradd,Nol11,Smad7,Sgk1,Rnpc3,Tet1,Hspb1,Ddx49,Rpl14,Srsf3,Prkaa2,Nup214,Tead1,Utp25,Cwc22,C1d,Paf1,Akt1,Lamtor4,Utp6,Papola,Prkcd,Hist2h4,Lsm3,Smad3,Cnot6l,Esrrg,Cdc5l,Dcp2,Rps24,Rplp0,Nr3c1,Ccne1,Snrpe,Psmd14,H3f3b,Zfp36l1,Notch1,Gsk3b,Rplp1,Hipk2,Hist2h3c2,Kmt5a,Rora,Wwox,Maml2,Psmd12,Rxra,Eif3j2,Tnrc6b,H2afy,Ncor2,Tbx5,Polr3b,Ctnnbl1,Ing2,Nrbf2,Gtf2e1,Taf13,Jmy,Hnrnph1,Gtf2a1,Gspt1,Mterf1b,Psmd7,Vdr,Trp53,Smad2,Tead4,Rpl35a,Nuak1,Prkag2,Csnk2a2,Nup153,Rara,Hnrnpr,Mllt3,Tet2,Taf11,Xab2,Rad17,Tigar,Ywhaq,Snrpb2,Hus1,Dnmt3a R-MMU-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.999862470363374 -0.000137539094693574 115 3 0.00309597523219814 969 8688 19294,243864,16415 Nectin2,Mill2,Itgb2l R-MMU-388396 GPCR downstream signaling 0.999892584348209 -0.000107421421265206 1065 85 0.087719298245614 969 8688 17200,18442,14702,21844,380698,56696,18430,50780,239766,54393,14773,320127,12775,12061,545156,224129,207212,237362,58182,258408,11553,233571,243407,18753,235611,109934,57257,11651,73341,16440,218461,16801,11516,20315,14683,11535,14675,242093,11548,258198,23945,11820,230972,19220,14677,52250,104418,11606,258830,15550,18755,432530,18619,18708,12778,51801,29863,22065,109648,12776,12922,14682,68338,387347,78134,50501,13615,52666,208188,15552,11515,269608,19353,277360,11549,15199,212541,213498,18754,16451,23984,15465,14527,67839,14678 Mc2r,P2ry2,Gng2,Tiam1,Obscn,Gpr132,Oxtr,Rgs3,Rtp1,Gabbr1,Grk5,Dgki,Ccr7,Bdkrb1,Kalrn,Adcy5,Arhgef17,Npffr1,Prokr1,Olfr463,Adra2c,P2ry6,Qrfprl,Prkcd,Plxnb1,Abr,Vav3,Akt1,Arhgef6,Itpr3,Pde8b,Arhgef1,Adcyap1,Cxcl12,Gnas,Adm,Gna14,Rxfp4,Adra1b,Olfr224,Mgll,App,Arhgef16,Ptgfr,Gnai1,Reep1,Dgkz,Agt,Olfr103,Htr1a,Prkch,Adcy1,Penk,Pik3r1,Ackr3,Ramp1,Pde7b,Trpc3,Npy,Ccr8,Crhr2,Gnaq,Golt1a,Tas2r118,Lpar4,Prok2,Edn2,Arhgef25,Ghsr,Htr1d,Adcy9,Plekhg5,Rac1,Prex1,Adra1a,Hebp1,Rho,Arhgef11,Prkce,Jak1,Pde10a,Hrh1,Gcgr,Gpsm1,Gnai2 R-MMU-6805567 Keratinization 0.999977236083614 -2.27641754880509e-05 150 4 0.00412796697626419 969 8688 406221,71529,18550,16665 Krt40,Kazn,Furin,Krt15 R-MMU-381753 Olfactory Signaling Pathway 0.999999999961418 -3.85822316787325e-11 535 5 0.00515995872033024 969 8688 239766,258198,258408,52250,258830 Rtp1,Olfr224,Olfr463,Reep1,Olfr103