TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols WP3592 ApoE and miR-146 in inflammation and atherosclerosis 0.90231858670905 -0.102787620937443 8 1 0.000801924619085806 1247 4946 24088 Tlr2 WP495 Glucocorticoid & Mineralcorticoid Metabolism 0.902376264922011 -0.102723700754008 14 2 0.00160384923817161 1247 4946 13070,13074 Cyp11a1,Cyp17a1 WP1771 Kennedy pathway 0.902376264922011 -0.102723700754008 14 2 0.00160384923817161 1247 4946 20397,12651 Sgpl1,Chkb WP55 Steroid Biosynthesis 0.902376264922011 -0.102723700754008 14 2 0.00160384923817161 1247 4946 15487,13074 Hsd17b3,Cyp17a1 WP1264 Estrogen metabolism 0.902376264922011 -0.102723700754008 14 2 0.00160384923817161 1247 4946 20887,12846 Sult1a1,Comt WP1498 Dopaminergic Neurogenesis 0.907172440110914 -0.097422725536555 30 5 0.00400962309542903 1247 4946 15376,13798,13195,14633,110648 Foxa2,En1,Ddc,Gli2,Lmx1a WP164 Glutathione metabolism 0.912537447562819 -0.0915261559425368 20 3 0.00240577385725742 1247 4946 14778,16790,14782 Gpx3,Anpep,Gsr WP1247 Methylation 0.926986209716685 -0.0758165897764652 9 1 0.000801924619085806 1247 4946 12846 Comt WP413 G1 to S cell cycle control 0.930636795401523 -0.0718862009146933 61 11 0.00882117080994387 1247 4946 17420,22390,50496,17246,13557,12571,13197,18974,12447,12443,17219 Mnat1,Wee1,E2f6,Mdm2,E2f3,Cdk6,Gadd45a,Pole2,Ccne1,Ccnd1,Mcm6 WP1244 Estrogen signaling 0.945409151066945 -0.0561374810982966 77 14 0.0112269446672013 1247 4946 13982,208727,20662,16476,20779,14683,12443,16150,12043,17420,13871,18706,26416,18033 Esr1,Hdac4,Sos1,Jun,Src,Gnas,Ccnd1,Ikbkb,Bcl2,Mnat1,Ercc2,Pik3ca,Mapk14,Nfkb1 WP683 Leptin and adiponectin 0.945428218325117 -0.0561173130410304 10 1 0.000801924619085806 1247 4946 11450 Adipoq WP79 Tryptophan metabolism 0.951639728895289 -0.0495687518501185 44 7 0.00561347233360064 1247 4946 13075,13195,12359,13123,70790,17246,22215 Cyp19a1,Ddc,Cat,Cyp7b1,Ubr5,Mdm2,Ube3a WP246 TNF-alpha NF-kB Signaling Pathway 0.959661178314947 -0.0411749960732362 193 39 0.0312750601443464 1247 4946 13728,16647,211550,21937,12389,223453,21941,21934,14229,21938,21353,80859,19946,22036,19696,15516,12633,20018,18035,20588,20846,14388,14082,22631,23938,544963,26410,12335,14083,16535,20779,22030,103583,18033,17463,22628,74256,22029,16150 Mark2,Kpna2,Tifa,Tnfrsf1a,Cav1,Dap,Tnfrsf8,Tnfrsf11a,Fkbp5,Tnfrsf1b,Tank,Nfkbiz,Rpl30,Traip,Rel,Hsp90ab1,Cflar,Polr1d,Nfkbia,Smarcc1,Stat1,Gab1,Fadd,Ywhaz,Map2k5,Iqgap2,Map3k8,Capn3,Ptk2,Kcnq1,Src,Traf2,Fbxw11,Nfkb1,Psmd7,Ywhag,Cyld,Traf1,Ikbkb WP2087 miRNA regulation of DNA Damage Response 0.959768649835181 -0.0410630133179722 65 11 0.00882117080994387 1247 4946 12443,12447,12122,228012,17873,13197,12571,17246,23882,17535,14102 Ccnd1,Ccne1,Bid,Tlk1,Gadd45b,Gadd45a,Cdk6,Mdm2,Gadd45g,Mre11a,Fas WP2316 PPAR signaling pathway 0.967286097672972 -0.0332609661981985 81 14 0.0112269446672013 1247 4946 18534,11806,56473,57875,12491,18607,94180,14079,433256,11450,11832,20250,225579,20181 Pck1,Apoa1,Fads2,Angptl4,Cd36,Pdpk1,Acsbg1,Fabp2,Acsl5,Adipoq,Aqp7,Scd2,Slc27a6,Rxra WP1398 Orphan GPCRs 0.970551039291339 -0.0298912870384095 19 2 0.00160384923817161 1247 4946 24100,240888 Tpra1,Gpr161 WP1263 Mitochondrial Gene Expression 0.970551039291339 -0.0298912870384095 19 2 0.00160384923817161 1247 4946 19055,12326 Ppp3ca,Camk4 WP2140 Serotonin and anxiety-related events 0.977223898748258 -0.0230394835444941 13 1 0.000801924619085806 1247 4946 19055 Ppp3ca WP216 Striated Muscle Contraction 0.983736682250893 -0.0163970170794992 45 6 0.00481154771451484 1247 4946 22003,21956,17930,59069,17929,12373 Tpm1,Tnnt2,Myom2,Tpm3,Myom1,Casq2 WP1269 Fatty Acid Beta Oxidation 0.984586223812489 -0.0155338034149816 34 4 0.00320769847634322 1247 4946 14571,12651,433256,15450 Gpd2,Chkb,Acsl5,Lipc WP307 Translation Factors 0.985372410712527 -0.0147356273233638 51 7 0.00561347233360064 1247 4946 18459,67204,68135,13690,13664,13666,230861 Pabpc2,Eif2s2,Eif3h,Eif4g2,Eif1a,Eif2ak3,Eif4g3 WP150 DNA Replication 0.988015311028768 -0.0120570843616658 41 5 0.00400962309542903 1247 4946 12545,18972,18974,17219,69263 Cdc7,Pold2,Pole2,Mcm6,Rfc3 WP200 Complement Activation, Classical Pathway 0.992902956918259 -0.00712234688452018 17 1 0.000801924619085806 1247 4946 17174 Masp1 WP108 Selenium metabolism/Selenoproteins 0.995802504792623 -0.00420632942009537 52 6 0.00481154771451484 1247 4946 109815,14778,19946,18033,13371,16476 Selenos,Gpx3,Rpl30,Nfkb1,Dio2,Jun WP567 Eukaryotic Transcription Initiation 0.997852742770668 -0.00214956589158995 43 4 0.00320769847634322 1247 4946 78929,13871,20018,17420 Polr3h,Ercc2,Polr1d,Mnat1 WP163 Cytoplasmic Ribosomal Proteins 0.998590431713999 -0.00141056266191481 102 14 0.0112269446672013 1247 4946 100502825,20090,19944,14109,19981,267019,68436,66475,19946,621697,114641,56040,19921,20111 Rpl37rt,Rps29,Rpl29,Fau,Rpl37a,Rps15a,Rpl34,Rps23,Rpl30,Rpl32l,Rpl31,Rplp1,Rpl19,Rps6ka1 WP189 GPCRs, Class A Rhodopsin-like 0.998951554270228 -0.00104899573346235 228 39 0.0312750601443464 1247 4946 11551,14062,15559,14063,22045,19220,14747,13618,12767,59289,17200,14767,74191,18430,14744,11542,84112,11548,81006,12062,14760,15557,170732,12801,140795,11554,19204,20608,18217,54199,18166,14429,12778,19065,70839,14738,12671,11549,18441 Adra2a,F2r,Htr2b,F2rl1,Trhr,Ptgfr,Cmklr1,Ednrb,Cxcr4,Ackr2,Mc2r,Nmur1,P2ry13,Oxtr,Gpr65,Adora3,Sucnr1,Adra1b,Gpr63,Bdkrb2,Gpr19,Htr1f,Trhr2,Cnr1,P2ry14,Adrb1,Ptafr,Sstr4,Ntsr2,Ccrl2,Npy1r,Galr3,Ackr3,Npy4r,P2ry12,Gpr12,Chrm3,Adra1a,P2ry1 WP519 Proteasome Degradation 0.999005977779092 -0.000994516588631839 59 6 0.00481154771451484 1247 4946 26440,17999,17463,51788,66998,26443 Psma1,Nedd4,Psmd7,H2afz,Psmd5,Psma6 WP1397 Odorant GPCRs 0.999987505512797 -1.24945652601875e-05 189 25 0.0200481154771451 1247 4946 107515,14747,18322,338346,215855,329252,14760,239530,83770,81006,100129,24100,70693,80910,14738,239845,233919,64378,353346,14160,381413,215798,240888,211577,73010 Lgr4,Cmklr1,Olfr24,Gpr21,Taar6,Lgr6,Gpr19,Gpr20,Tas1r2,Gpr63,Gpr153,Tpra1,Adgra3,Gpr84,Gpr12,Gpr156,Gpr26,Gpr88,Gpr141,Lgr5,Gpr176,Adgrg6,Gpr161,Mrgprf,Gpr22 WP41 GPCRs, Other 0.999991218526162 -8.78151239524024e-06 164 20 0.0160384923817161 1247 4946 18322,11554,13617,64379,113855,170732,12801,13609,12775,14816,71111,319757,80910,208188,11542,18346,64378,258153,14369,12374 Olfr24,Adrb1,Ednra,Irx6,Vmn1r40,Trhr2,Cnr1,S1pr1,Ccr7,Grm1,Gpr39,Smo,Gpr84,Ghsr,Adora3,Olfr47,Gpr88,Olfr412,Fzd7,Casr WP1248 Oxidative phosphorylation 0.999996773944453 -3.22606075095055e-06 62 3 0.00240577385725742 1247 4946 70495,11957,28080 Atp6ap2,Atp5j,Atp5o WP295 Electron Transport Chain 0.999999742538411 -2.57461622055214e-07 109 8 0.00641539695268645 1247 4946 28080,11957,20463,12864,68194,22228,22229,11739 Atp5o,Atp5j,Cox7a2l,Cox6c,Ndufb4,Ucp2,Ucp3,Slc25a4 WP310 mRNA processing 0.999999999875689 -1.24311041184598e-10 484 66 0.0529270248596632 1247 4946 66446,207920,56516,20924,53975,66475,20383,100502825,20817,217337,67543,68981,12021,56878,53791,268859,58203,20238,20090,56195,19383,11992,56758,229279,59093,353258,216578,192119,20747,19357,66405,50911,83675,93686,56417,208718,15387,230603,67465,18459,11739,67390,217207,235402,50783,621697,71713,22184,70439,230861,20813,13690,107686,20823,76522,12828,66184,207181,239188,19317,66230,19921,108013,72692,320158,64340 Exosc7,Esrp1,Rbms2,Supt5,Ddx20,Rps23,Srsf3,Rpl37rt,Srpk2,Srp68,Pabpc6,Snrpa1,Bard1,Rbms1,Tlr5,Rbfox1,Zbp1,Atxn1,Rps29,Ptbp2,Raly,Auh,Mbnl1,Hnrnpa3,Pcbp3,Ltv1,Papolg,Dicer1,Spop,Rad21,Mcts2,Exosc9,Bicc1,Rbfox2,Adar,Dis3l2,Hnrnpk,Ttc39a,Sf3a1,Pabpc2,Slc25a4,Mrm3,Dhx8,Lingo1,Lsm4,Rpl32l,Cdc40,Zrsr2,Taf15,Eif4g3,Srp14,Eif4g2,Snrpd2,Ssb,Lsm8,Col4a3,Rps4l,Rbms3,Enox1,Qk,Mrps28,Rpl19,Celf4,Hnrnpll,Zmat4,Dhx38