Gene to GO MF test for over-representation
GOMFID Pvalue OddsRatio ExpCount Count Size Term
GO:0005488 0.00000 2.24122 163 212 13121 binding
GO:0005515 0.00000 1.97560 111 158 8965 protein binding
GO:0046873 0.00000 4.43776 5 21 421 metal ion transmembrane transporter activity
GO:0015085 0.00000 7.43270 2 11 133 calcium ion transmembrane transporter activity
GO:0005262 0.00000 7.75388 1 10 116 calcium channel activity
GO:0022890 0.00000 3.44160 7 22 561 inorganic cation transmembrane transporter activity
GO:0008324 0.00001 3.15878 8 22 608 cation transmembrane transporter activity
GO:0005261 0.00001 4.23603 4 15 309 cation channel activity
GO:0043167 0.00001 1.75740 67 99 5386 ion binding
GO:0015318 0.00002 2.78534 10 25 783 inorganic molecular entity transmembrane transporter activity
GO:0015075 0.00002 2.70792 10 26 838 ion transmembrane transporter activity
GO:0043169 0.00002 1.84106 44 71 3542 cation binding
GO:0046872 0.00003 1.83139 43 69 3445 metal ion binding
GO:0015267 0.00004 3.37489 5 17 436 channel activity
GO:0022803 0.00004 3.37489 5 17 436 passive transmembrane transporter activity
GO:0004768 0.00004 80.49821 0 3 6 stearoyl-CoA 9-desaturase activity
GO:0044212 0.00004 2.53085 12 27 929 transcription regulatory region DNA binding
GO:0001067 0.00004 2.51921 12 27 933 regulatory region nucleic acid binding
GO:0005216 0.00005 3.43106 5 16 403 ion channel activity
GO:0022857 0.00005 2.44247 12 28 998 transmembrane transporter activity
GO:0005310 0.00006 13.96303 0 5 34 dicarboxylic acid transmembrane transporter activity
GO:0015141 0.00006 60.37097 0 3 7 succinate transmembrane transporter activity
GO:0016215 0.00006 60.37097 0 3 7 acyl-CoA desaturase activity
GO:0022838 0.00007 3.31759 5 16 416 substrate-specific channel activity
GO:0003700 0.00008 2.37833 13 28 1023 DNA-binding transcription factor activity
GO:0005102 0.00009 2.02857 22 41 1779 signaling receptor binding
GO:0038191 0.00010 20.18525 0 4 20 neuropilin binding
GO:0016717 0.00010 48.29462 0 3 8 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0017153 0.00010 48.29462 0 3 8 sodium:dicarboxylate symporter activity
GO:0005215 0.00010 2.27063 14 30 1149 transporter activity
GO:0015291 0.00011 4.30104 3 11 221 secondary active transmembrane transporter activity
GO:0043177 0.00011 4.28046 3 11 222 organic acid binding
GO:0030617 0.00015 Inf 0 2 2 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
GO:0016709 0.00019 10.65172 1 5 43 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0005509 0.00020 2.71595 7 19 601 calcium ion binding
GO:0015368 0.00021 34.49309 0 3 10 calcium:cation antiporter activity
GO:0005539 0.00023 4.26432 3 10 202 glycosaminoglycan binding
GO:0005343 0.00024 15.37581 0 4 25 organic acid:sodium symporter activity
GO:0016705 0.00024 4.21998 3 10 204 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0031406 0.00027 4.15516 3 10 207 carboxylic acid binding
GO:0015081 0.00033 5.01561 2 8 138 sodium ion transmembrane transporter activity
GO:0022843 0.00039 4.90182 2 8 141 voltage-gated cation channel activity
GO:0000981 0.00041 2.37416 10 22 795 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0042802 0.00041 1.88255 23 40 1853 identical protein binding
GO:0005172 0.00049 24.14194 0 3 13 vascular endothelial growth factor receptor binding
GO:0015556 0.00049 24.14194 0 3 13 C4-dicarboxylate transmembrane transporter activity
GO:0015077 0.00054 3.11647 4 13 356 monovalent inorganic cation transmembrane transporter activity
GO:0043565 0.00059 2.11271 14 27 1099 sequence-specific DNA binding
GO:0140110 0.00060 2.00231 17 31 1336 transcription regulator activity
GO:0000976 0.00061 2.29713 10 22 820 transcription regulatory region sequence-specific DNA binding
GO:0000977 0.00072 2.31647 10 21 775 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001012 0.00082 2.29131 10 21 783 RNA polymerase II regulatory region DNA binding
GO:0008514 0.00088 3.86443 2 9 199 organic anion transmembrane transporter activity
GO:0030297 0.00090 80.21429 0 2 4 transmembrane receptor protein tyrosine kinase activator activity
GO:0032896 0.00090 80.21429 0 2 4 palmitoyl-CoA 9-desaturase activity
GO:0030296 0.00094 18.56824 0 3 16 protein tyrosine kinase activator activity
GO:1990837 0.00112 2.18615 11 22 859 sequence-specific double-stranded DNA binding
GO:0051184 0.00113 17.24117 0 3 17 cofactor transmembrane transporter activity
GO:0030020 0.00123 9.49132 0 4 38 extracellular matrix structural constituent conferring tensile strength
GO:0000982 0.00130 2.59489 6 15 491 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
GO:0000978 0.00131 2.50360 7 16 543 RNA polymerase II proximal promoter sequence-specific DNA binding
GO:0015297 0.00136 6.62869 1 5 66 antiporter activity
GO:0003828 0.00149 53.47381 0 2 5 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0005432 0.00149 53.47381 0 2 5 calcium:sodium antiporter activity
GO:0008273 0.00149 53.47381 0 2 5 calcium, potassium:sodium antiporter activity
GO:0015137 0.00149 53.47381 0 2 5 citrate transmembrane transporter activity
GO:0015142 0.00149 53.47381 0 2 5 tricarboxylic acid transmembrane transporter activity
GO:0072345 0.00149 53.47381 0 2 5 NAADP-sensitive calcium-release channel activity
GO:0000987 0.00167 2.44188 7 16 556 proximal promoter sequence-specific DNA binding
GO:0005201 0.00178 4.30606 2 7 139 extracellular matrix structural constituent
GO:1902936 0.00199 4.91063 1 6 105 phosphatidylinositol bisphosphate binding
GO:0022839 0.00203 2.95856 4 11 315 ion gated channel activity
GO:0015293 0.00209 4.17866 2 7 143 symporter activity
GO:0005540 0.00213 13.40741 0 3 21 hyaluronic acid binding
GO:0005072 0.00222 40.10357 0 2 6 transforming growth factor beta receptor, cytoplasmic mediator activity
GO:0043184 0.00222 40.10357 0 2 6 vascular endothelial growth factor receptor 2 binding
GO:0099508 0.00222 40.10357 0 2 6 voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:0005342 0.00226 4.11773 2 7 145 organic acid transmembrane transporter activity
GO:0046943 0.00226 4.11773 2 7 145 carboxylic acid transmembrane transporter activity
GO:0030215 0.00244 12.70119 0 3 22 semaphorin receptor binding
GO:0022836 0.00252 2.87232 4 11 324 gated channel activity
GO:0005244 0.00255 3.59414 2 8 189 voltage-gated ion channel activity
GO:0022832 0.00255 3.59414 2 8 189 voltage-gated channel activity
GO:0098772 0.00258 1.74949 21 35 1718 molecular function regulator
GO:0008201 0.00273 3.97287 2 7 150 heparin binding
GO:0005113 0.00309 32.08143 0 2 7 patched binding
GO:0015491 0.00315 11.49053 0 3 24 cation:cation antiporter activity
GO:0046914 0.00336 1.98805 12 22 939 transition metal ion binding
GO:0050660 0.00336 5.31683 1 5 81 flavin adenine dinucleotide binding
GO:0003690 0.00371 1.97012 12 22 947 double-stranded DNA binding
GO:0022804 0.00380 2.71392 4 11 342 active transmembrane transporter activity
GO:0099516 0.00393 6.71882 1 4 52 ion antiporter activity
GO:0005506 0.00477 3.57052 2 7 166 iron ion binding
GO:0045499 0.00491 9.65032 0 3 28 chemorepellent activity
GO:0030546 0.00521 22.91327 0 2 9 receptor activator activity
GO:0042895 0.00521 22.91327 0 2 9 antibiotic transmembrane transporter activity
GO:0001228 0.00542 2.36395 6 13 463 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0015298 0.00543 9.27874 0 3 29 solute:cation antiporter activity
GO:0050840 0.00617 5.86187 1 4 59 extracellular matrix binding
GO:0015294 0.00633 4.53758 1 5 94 solute:cation symporter activity
GO:0043168 0.00684 1.53251 33 47 2640 anion binding
GO:0017154 0.00783 17.81984 0 2 11 semaphorin receptor activity
GO:0070411 0.00783 17.81984 0 2 11 I-SMAD binding
GO:0015238 0.00785 4.29526 1 5 99 drug transmembrane transporter activity
GO:0099094 0.00785 4.29526 1 5 99 ligand-gated cation channel activity
GO:0001077 0.00813 2.56012 4 10 328 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0071949 0.00850 7.78044 0 3 34 FAD binding
GO:0015370 0.00913 5.19842 1 4 66 solute:sodium symporter activity
GO:0070851 0.00925 3.51670 2 6 144 growth factor receptor binding
GO:0005283 0.00931 16.03714 0 2 12 amino acid:sodium symporter activity
GO:0034713 0.00931 16.03714 0 2 12 type I transforming growth factor beta receptor binding
GO:0036122 0.00931 16.03714 0 2 12 BMP binding
GO:0008289 0.00973 1.96251 9 17 728 lipid binding
GO:0033293 0.01013 5.03552 1 4 68 monocarboxylic acid binding
GO:0005518 0.01065 4.95783 1 4 69 collagen binding
GO:0015279 0.01092 14.57857 0 2 13 store-operated calcium channel activity
GO:0016491 0.01105 1.89528 10 18 798 oxidoreductase activity
GO:0030971 0.01118 4.88249 1 4 70 receptor tyrosine kinase binding
GO:1901681 0.01145 2.74972 3 8 244 sulfur compound binding
GO:0003885 0.01240 Inf 0 1 1 D-arabinono-1,4-lactone oxidase activity
GO:0003979 0.01240 Inf 0 1 1 UDP-glucose 6-dehydrogenase activity
GO:0003983 0.01240 Inf 0 1 1 UTP:glucose-1-phosphate uridylyltransferase activity
GO:0004163 0.01240 Inf 0 1 1 diphosphomevalonate decarboxylase activity
GO:0004341 0.01240 Inf 0 1 1 gluconolactonase activity
GO:0004498 0.01240 Inf 0 1 1 calcidiol 1-monooxygenase activity
GO:0004506 0.01240 Inf 0 1 1 squalene monooxygenase activity
GO:0005142 0.01240 Inf 0 1 1 interleukin-11 receptor binding
GO:0005309 0.01240 Inf 0 1 1 creatine:sodium symporter activity
GO:0005365 0.01240 Inf 0 1 1 myo-inositol transmembrane transporter activity
GO:0005366 0.01240 Inf 0 1 1 myo-inositol:proton symporter activity
GO:0008418 0.01240 Inf 0 1 1 protein-N-terminal asparagine amidohydrolase activity
GO:0008434 0.01240 Inf 0 1 1 calcitriol receptor activity
GO:0008832 0.01240 Inf 0 1 1 dGTPase activity
GO:0015343 0.01240 Inf 0 1 1 siderophore transmembrane transporter activity
GO:0016793 0.01240 Inf 0 1 1 triphosphoric monoester hydrolase activity
GO:0030305 0.01240 Inf 0 1 1 heparanase activity
GO:0031695 0.01240 Inf 0 1 1 alpha-2B adrenergic receptor binding
GO:0031704 0.01240 Inf 0 1 1 apelin receptor binding
GO:0032395 0.01240 Inf 0 1 1 MHC class II receptor activity
GO:0032560 0.01240 Inf 0 1 1 guanyl deoxyribonucleotide binding
GO:0032567 0.01240 Inf 0 1 1 dGTP binding
GO:0033971 0.01240 Inf 0 1 1 hydroxyisourate hydrolase activity
GO:0038186 0.01240 Inf 0 1 1 lithocholic acid receptor activity
GO:0042931 0.01240 Inf 0 1 1 enterobactin transmembrane transporter activity
GO:0050105 0.01240 Inf 0 1 1 L-gulonolactone oxidase activity
GO:0051748 0.01240 Inf 0 1 1 UTP-monosaccharide-1-phosphate uridylyltransferase activity
GO:0052731 0.01240 Inf 0 1 1 phosphocholine phosphatase activity
GO:0052732 0.01240 Inf 0 1 1 phosphoethanolamine phosphatase activity
GO:0052899 0.01240 Inf 0 1 1 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0052902 0.01240 Inf 0 1 1 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity
GO:0052903 0.01240 Inf 0 1 1 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0052904 0.01240 Inf 0 1 1 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
GO:0060422 0.01240 Inf 0 1 1 peptidyl-dipeptidase inhibitor activity
GO:0070320 0.01240 Inf 0 1 1 inward rectifier potassium channel inhibitor activity
GO:1902098 0.01240 Inf 0 1 1 calcitriol binding
GO:1990699 0.01240 Inf 0 1 1 palmitoleyl hydrolase activity
GO:0046983 0.01255 1.65715 17 27 1376 protein dimerization activity
GO:0030545 0.01309 2.10123 6 13 518 receptor regulator activity
GO:0008509 0.01321 2.50301 4 9 301 anion transmembrane transporter activity
GO:0008134 0.01335 1.93262 9 16 694 transcription factor binding
GO:0030295 0.01351 4.60267 1 4 74 protein kinase activator activity
GO:0015079 0.01414 3.19079 2 6 158 potassium ion transmembrane transporter activity
GO:0015116 0.01446 12.33462 0 2 15 sulfate transmembrane transporter activity
GO:0022821 0.01446 12.33462 0 2 15 potassium ion antiporter activity
GO:1901981 0.01455 3.16979 2 6 159 phosphatidylinositol phosphate binding
GO:0005546 0.01478 4.47442 1 4 76 phosphatidylinositol-4,5-bisphosphate binding
GO:0005109 0.01516 6.18224 1 3 42 frizzled binding
GO:0030165 0.01539 3.60205 1 5 117 PDZ domain binding
GO:1901618 0.01615 6.02742 1 3 43 organic hydroxy compound transmembrane transporter activity
GO:0005416 0.01639 11.45306 0 2 16 amino acid:cation symporter activity
GO:0048018 0.01825 2.07062 6 12 484 receptor ligand activity
GO:0019209 0.01827 4.18294 1 4 81 kinase activator activity
GO:0004622 0.01843 10.68905 0 2 17 lysophospholipase activity
GO:0005245 0.02047 5.47849 1 3 47 voltage-gated calcium channel activity
GO:0005249 0.02224 3.92700 1 4 86 voltage-gated potassium channel activity
GO:0015276 0.02451 3.17448 2 5 132 ligand-gated ion channel activity
GO:0022834 0.02451 3.17448 2 5 132 ligand-gated channel activity
GO:0050839 0.02455 2.55004 3 7 229 cell adhesion molecule binding
GO:0004067 0.02464 79.93238 0 1 2 asparaginase activity
GO:0004360 0.02464 79.93238 0 1 2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0004421 0.02464 79.93238 0 1 2 hydroxymethylglutaryl-CoA synthase activity
GO:0004666 0.02464 79.93238 0 1 2 prostaglandin-endoperoxide synthase activity
GO:0005308 0.02464 79.93238 0 1 2 creatine transmembrane transporter activity
GO:0008269 0.02464 79.93238 0 1 2 JAK pathway signal transduction adaptor activity
GO:0008459 0.02464 79.93238 0 1 2 chondroitin 6-sulfotransferase activity
GO:0030116 0.02464 79.93238 0 1 2 glial cell-derived neurotrophic factor receptor binding
GO:0031696 0.02464 79.93238 0 1 2 alpha-2C adrenergic receptor binding
GO:0038062 0.02464 79.93238 0 1 2 protein tyrosine kinase collagen receptor activity
GO:0043183 0.02464 79.93238 0 1 2 vascular endothelial growth factor receptor 1 binding
GO:0045183 0.02464 79.93238 0 1 2 translation factor activity, non-nucleic acid binding
GO:0046556 0.02464 79.93238 0 1 2 alpha-L-arabinofuranosidase activity
GO:0046592 0.02464 79.93238 0 1 2 polyamine oxidase activity
GO:0052901 0.02464 79.93238 0 1 2 spermine:oxygen oxidoreductase (spermidine-forming) activity
GO:0098770 0.02464 79.93238 0 1 2 FBXO family protein binding
GO:0099580 0.02464 79.93238 0 1 2 ion antiporter activity involved in regulation of postsynaptic membrane potential
GO:1902121 0.02464 79.93238 0 1 2 lithocholic acid binding
GO:1902271 0.02464 79.93238 0 1 2 D3 vitamins binding
GO:1905060 0.02464 79.93238 0 1 2 calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration
GO:1990409 0.02464 79.93238 0 1 2 adrenomedullin binding
GO:1990782 0.02485 3.78790 1 4 89 protein tyrosine kinase binding
GO:0008373 0.02513 8.90635 0 2 20 sialyltransferase activity
GO:0015278 0.02513 8.90635 0 2 20 calcium-release channel activity
GO:0001664 0.02635 2.33840 4 8 285 G protein-coupled receptor binding
GO:0050662 0.02635 2.33840 4 8 285 coenzyme binding
GO:0044325 0.02668 3.10081 2 5 135 ion channel binding
GO:0005160 0.02802 4.81978 1 3 53 transforming growth factor beta receptor binding
GO:0005544 0.02802 4.81978 1 3 53 calcium-dependent phospholipid binding
GO:0003677 0.02987 1.45053 25 35 2034 DNA binding
GO:0030234 0.02988 1.65959 12 19 956 enzyme regulator activity
GO:0035091 0.03241 2.39726 3 7 243 phosphatidylinositol binding
GO:0015026 0.03266 7.63299 0 2 23 coreceptor activity
GO:0071837 0.03266 7.63299 0 2 23 HMG box domain binding
GO:0004497 0.03304 2.92000 2 5 143 monooxygenase activity
GO:0048037 0.03358 1.88280 7 12 530 cofactor binding
GO:0070412 0.03534 7.28571 0 2 24 R-SMAD binding
GO:0042803 0.03599 1.64491 11 18 912 protein homodimerization activity
GO:0004470 0.03674 39.96441 0 1 3 malic enzyme activity
GO:0004471 0.03674 39.96441 0 1 3 malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004473 0.03674 39.96441 0 1 3 malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0004517 0.03674 39.96441 0 1 3 nitric-oxide synthase activity
GO:0004748 0.03674 39.96441 0 1 3 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0004949 0.03674 39.96441 0 1 3 cannabinoid receptor activity
GO:0004962 0.03674 39.96441 0 1 3 endothelin receptor activity
GO:0005119 0.03674 39.96441 0 1 3 smoothened binding
GO:0008158 0.03674 39.96441 0 1 3 hedgehog receptor activity
GO:0008401 0.03674 39.96441 0 1 3 retinoic acid 4-hydroxylase activity
GO:0015117 0.03674 39.96441 0 1 3 thiosulfate transmembrane transporter activity
GO:0015131 0.03674 39.96441 0 1 3 oxaloacetate transmembrane transporter activity
GO:0016401 0.03674 39.96441 0 1 3 palmitoyl-CoA oxidase activity
GO:0016647 0.03674 39.96441 0 1 3 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
GO:0016728 0.03674 39.96441 0 1 3 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
GO:0038181 0.03674 39.96441 0 1 3 bile acid receptor activity
GO:0046870 0.03674 39.96441 0 1 3 cadmium ion binding
GO:0050196 0.03674 39.96441 0 1 3 [phosphorylase] phosphatase activity
GO:0061731 0.03674 39.96441 0 1 3 ribonucleoside-diphosphate reductase activity
GO:0070548 0.03674 39.96441 0 1 3 L-glutamine aminotransferase activity
GO:0070644 0.03674 39.96441 0 1 3 vitamin D response element binding
GO:0070698 0.03674 39.96441 0 1 3 type I activin receptor binding
GO:2001069 0.03674 39.96441 0 1 3 glycogen binding
GO:2001070 0.03674 39.96441 0 1 3 starch binding
GO:0019899 0.03725 1.40317 28 38 2282 enzyme binding
GO:0043325 0.03810 6.96863 0 2 25 phosphatidylinositol-3,4-bisphosphate binding
GO:0005070 0.04095 6.67798 0 2 26 SH3/SH2 adaptor activity
GO:0005328 0.04095 6.67798 0 2 26 neurotransmitter:sodium symporter activity
GO:0033612 0.04095 6.67798 0 2 26 receptor serine/threonine kinase binding
GO:0099604 0.04095 6.67798 0 2 26 ligand-gated calcium channel activity
GO:0052689 0.04320 2.70310 2 5 154 carboxylic ester hydrolase activity
GO:0020037 0.04421 2.68496 2 5 155 heme binding
GO:0005126 0.04832 2.05942 4 8 322 cytokine receptor binding
GO:0001605 0.04868 26.64176 0 1 4 adrenomedullin receptor activity
GO:0004427 0.04868 26.64176 0 1 4 inorganic diphosphatase activity
GO:0005314 0.04868 26.64176 0 1 4 high-affinity glutamate transmembrane transporter activity
GO:0008948 0.04868 26.64176 0 1 4 oxaloacetate decarboxylase activity
GO:0015140 0.04868 26.64176 0 1 4 malate transmembrane transporter activity
GO:0015501 0.04868 26.64176 0 1 4 glutamate:sodium symporter activity
GO:0030229 0.04868 26.64176 0 1 4 very-low-density lipoprotein particle receptor activity
GO:0031694 0.04868 26.64176 0 1 4 alpha-2A adrenergic receptor binding
GO:0033300 0.04868 26.64176 0 1 4 dehydroascorbic acid transmembrane transporter activity
GO:0035939 0.04868 26.64176 0 1 4 microsatellite binding
GO:0055056 0.04868 26.64176 0 1 4 D-glucose transmembrane transporter activity
GO:0097108 0.04868 26.64176 0 1 4 hedgehog family protein binding
GO:0097109 0.04868 26.64176 0 1 4 neuroligin family protein binding
GO:0097643 0.04868 26.64176 0 1 4 amylin receptor activity
GO:0097644 0.04868 26.64176 0 1 4 calcitonin family binding
GO:1905030 0.04868 26.64176 0 1 4 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential