Gene to GO MF test for over-representation
GOMFID Pvalue OddsRatio ExpCount Count Size Term
GO:0005509 0.00000 2.45449 50 106 685 calcium ion binding
GO:0005201 0.00000 5.40804 6 23 78 extracellular matrix structural constituent
GO:0005539 0.00000 3.00937 16 40 213 glycosaminoglycan binding
GO:1901681 0.00000 2.87875 17 42 232 sulfur compound binding
GO:0043167 0.00000 1.38052 446 535 6125 ion binding
GO:0032403 0.00000 1.89338 58 100 799 protein complex binding
GO:0043168 0.00000 1.48628 197 265 2704 anion binding
GO:0008201 0.00000 3.24188 12 32 160 heparin binding
GO:0004871 0.00000 1.56588 125 179 1714 signal transducer activity
GO:0060089 0.00000 1.56689 121 174 1663 molecular transducer activity
GO:0004872 0.00000 1.56099 118 169 1618 receptor activity
GO:0005102 0.00000 1.57476 112 162 1537 receptor binding
GO:0005518 0.00000 4.56011 5 17 65 collagen binding
GO:0005178 0.00000 3.37307 8 23 111 integrin binding
GO:0044877 0.00001 1.63530 73 110 997 macromolecular complex binding
GO:0097367 0.00001 1.43212 158 209 2166 carbohydrate derivative binding
GO:0098772 0.00001 1.46800 131 179 1806 molecular function regulator
GO:0005096 0.00001 2.25279 21 42 284 GTPase activator activity
GO:0008047 0.00001 1.89018 37 65 514 enzyme activator activity
GO:0003779 0.00001 2.01466 29 54 403 actin binding
GO:0043394 0.00001 5.92695 3 12 38 proteoglycan binding
GO:0038023 0.00001 1.51328 102 143 1395 signaling receptor activity
GO:0030695 0.00002 2.12304 23 44 313 GTPase regulator activity
GO:0052813 0.00003 3.88265 5 16 69 phosphatidylinositol bisphosphate kinase activity
GO:0046934 0.00006 3.78017 5 15 66 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0008092 0.00006 1.58912 63 94 869 cytoskeletal protein binding
GO:0099600 0.00007 1.47283 97 134 1334 transmembrane receptor activity
GO:0004888 0.00007 1.48100 94 130 1287 transmembrane signaling receptor activity
GO:0035004 0.00007 3.54683 5 16 74 phosphatidylinositol 3-kinase activity
GO:0004713 0.00010 2.39333 13 28 179 protein tyrosine kinase activity
GO:0030234 0.00012 1.51777 74 106 1022 enzyme regulator activity
GO:0031013 0.00013 51.11994 0 4 5 troponin I binding
GO:0005515 0.00019 1.25283 827 885 11367 protein binding
GO:0042056 0.00020 5.49214 2 9 30 chemoattractant activity
GO:0070851 0.00021 2.57550 10 22 132 growth factor receptor binding
GO:0017124 0.00026 2.59915 9 21 125 SH3 domain binding
GO:0060589 0.00027 1.86197 25 44 350 nucleoside-triphosphatase regulator activity
GO:0008083 0.00028 2.35163 12 25 162 growth factor activity
GO:0019904 0.00037 1.57533 51 75 695 protein domain specific binding
GO:0004955 0.00037 12.78696 1 5 10 prostaglandin receptor activity
GO:0004953 0.00041 8.52930 1 6 15 icosanoid receptor activity
GO:0004714 0.00044 3.40483 5 13 62 transmembrane receptor protein tyrosine kinase activity
GO:0046983 0.00045 1.41835 91 122 1250 protein dimerization activity
GO:0019199 0.00051 3.00988 6 15 79 transmembrane receptor protein kinase activity
GO:0005548 0.00058 3.49836 4 12 56 phospholipid transporter activity
GO:0005262 0.00062 2.54476 8 19 115 calcium channel activity
GO:0005001 0.00062 7.67589 1 6 16 transmembrane receptor protein tyrosine phosphatase activity
GO:0019198 0.00062 7.67589 1 6 16 transmembrane receptor protein phosphatase activity
GO:0046875 0.00064 5.12223 2 8 28 ephrin receptor binding
GO:0004954 0.00065 10.65514 1 5 11 prostanoid receptor activity
GO:0050839 0.00069 1.67525 34 53 463 cell adhesion molecule binding
GO:0016773 0.00085 1.50258 56 80 773 phosphotransferase activity, alcohol group as acceptor
GO:0042043 0.00104 9.13241 1 5 12 neurexin family protein binding
GO:0008237 0.00108 2.07967 14 26 187 metallopeptidase activity
GO:0008289 0.00112 1.52813 48 70 665 lipid binding
GO:0022836 0.00115 1.76962 24 40 332 gated channel activity
GO:0005261 0.00139 1.77749 23 38 314 cation channel activity
GO:0017048 0.00142 2.14422 12 23 161 Rho GTPase binding
GO:0005085 0.00195 1.73901 23 38 320 guanyl-nucleotide exchange factor activity
GO:0015085 0.00198 2.21586 10 20 136 calcium ion transmembrane transporter activity
GO:0016301 0.00200 1.43722 61 84 844 kinase activity
GO:0048365 0.00200 2.95868 5 12 64 Rac GTPase binding
GO:0042802 0.00213 1.31505 117 147 1612 identical protein binding
GO:0001618 0.00215 2.77871 5 13 73 virus receptor activity
GO:0104005 0.00215 2.77871 5 13 73 hijacked molecular function
GO:0070006 0.00234 5.48142 1 6 20 metalloaminopeptidase activity
GO:0001968 0.00259 4.47838 2 7 27 fibronectin binding
GO:0042803 0.00269 1.43866 57 78 782 protein homodimerization activity
GO:0005216 0.00269 1.60669 31 47 425 ion channel activity
GO:0008235 0.00276 2.99918 4 11 58 metalloexopeptidase activity
GO:0004115 0.00328 6.39149 1 5 15 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005161 0.00328 6.39149 1 5 15 platelet-derived growth factor receptor binding
GO:0008191 0.00328 6.39149 1 5 15 metalloendopeptidase inhibitor activity
GO:0004715 0.00330 3.12421 4 10 51 non-membrane spanning protein tyrosine kinase activity
GO:0004499 0.00344 19.15357 0 3 5 N,N-dimethylaniline monooxygenase activity
GO:0008273 0.00344 19.15357 0 3 5 calcium, potassium:sodium antiporter activity
GO:0043533 0.00344 19.15357 0 3 5 inositol 1,3,4,5 tetrakisphosphate binding
GO:0048018 0.00393 1.55539 33 49 456 receptor ligand activity
GO:0004672 0.00403 1.46146 47 65 641 protein kinase activity
GO:0004185 0.00411 8.51734 1 4 10 serine-type carboxypeptidase activity
GO:0005088 0.00422 1.77158 18 30 248 Ras guanyl-nucleotide exchange factor activity
GO:0022838 0.00422 1.56428 32 47 435 substrate-specific channel activity
GO:0005547 0.00444 3.53059 3 8 37 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0051015 0.00457 1.99843 11 21 156 actin filament binding
GO:0046873 0.00473 1.54577 33 48 449 metal ion transmembrane transporter activity
GO:0072509 0.00482 1.91952 13 23 177 divalent inorganic cation transmembrane transporter activity
GO:0015491 0.00490 3.89352 2 7 30 cation:cation antiporter activity
GO:0099094 0.00491 2.48731 6 13 80 ligand-gated cation channel activity
GO:0005244 0.00494 1.85807 14 25 198 voltage-gated ion channel activity
GO:0022832 0.00494 1.85807 14 25 198 voltage-gated channel activity
GO:0099604 0.00505 4.51327 2 6 23 ligand-gated calcium channel activity
GO:0002114 0.00529 Inf 0 2 2 interleukin-33 receptor activity
GO:0004119 0.00529 Inf 0 2 2 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
GO:0004947 0.00529 Inf 0 2 2 bradykinin receptor activity
GO:0005006 0.00529 Inf 0 2 2 epidermal growth factor-activated receptor activity
GO:0005365 0.00529 Inf 0 2 2 myo-inositol transmembrane transporter activity
GO:0019912 0.00529 Inf 0 2 2 cyclin-dependent protein kinase activating kinase activity
GO:0008081 0.00536 2.36199 7 14 90 phosphoric diester hydrolase activity
GO:0015276 0.00575 2.03275 10 19 139 ligand-gated ion channel activity
GO:0022834 0.00575 2.03275 10 19 139 ligand-gated channel activity
GO:0097110 0.00580 2.84579 4 10 55 scaffold protein binding
GO:0005543 0.00589 1.58285 27 41 375 phospholipid binding
GO:0017147 0.00594 3.73106 2 7 31 Wnt-protein binding
GO:0016175 0.00608 7.30012 1 4 11 superoxide-generating NADPH oxidase activity
GO:0019238 0.00651 12.76825 0 3 6 cyclohydrolase activity
GO:0005516 0.00657 1.83593 14 24 192 calmodulin binding
GO:0005057 0.00719 2.07721 9 17 122 signal transducer activity, downstream of receptor
GO:0046872 0.00725 1.18049 300 336 4116 metal ion binding
GO:0015278 0.00780 4.91562 1 5 18 calcium-release channel activity
GO:0030545 0.00797 1.48355 35 50 485 receptor regulator activity
GO:0004180 0.00849 3.10187 3 8 41 carboxypeptidase activity
GO:0008331 0.00861 6.38721 1 4 12 high voltage-gated calcium channel activity
GO:0015368 0.00861 6.38721 1 4 12 calcium:cation antiporter activity
GO:0004222 0.00907 2.07263 8 16 115 metalloendopeptidase activity
GO:1901981 0.00909 1.97393 10 18 135 phosphatidylinositol phosphate binding
GO:0015267 0.00933 1.48129 34 48 466 channel activity
GO:0005089 0.00940 2.36502 6 12 77 Rho guanyl-nucleotide exchange factor activity
GO:0051219 0.00940 2.36502 6 12 77 phosphoprotein binding
GO:0038024 0.00959 2.47147 5 11 68 cargo receptor activity
GO:0022803 0.00969 1.47766 34 48 467 passive transmembrane transporter activity
GO:0004653 0.00996 4.56422 1 5 19 polypeptide N-acetylgalactosaminyltransferase activity
GO:0004970 0.00996 4.56422 1 5 19 ionotropic glutamate receptor activity
GO:0008376 0.01005 3.31588 2 7 34 acetylgalactosaminyltransferase activity
GO:0035091 0.01043 1.71339 16 26 221 phosphatidylinositol binding
GO:0003774 0.01052 1.94051 10 18 137 motor activity
GO:0050840 0.01053 2.74248 4 9 51 extracellular matrix binding
GO:0052742 0.01053 2.74248 4 9 51 phosphatidylinositol kinase activity
GO:0004908 0.01077 9.57560 1 3 7 interleukin-1 receptor activity
GO:0042608 0.01077 9.57560 1 3 7 T cell receptor binding
GO:0042609 0.01077 9.57560 1 3 7 CD4 receptor binding
GO:0019887 0.01115 1.76865 14 23 190 protein kinase regulator activity
GO:0008238 0.01147 2.06757 8 15 108 exopeptidase activity
GO:0019207 0.01153 1.71745 15 25 212 kinase regulator activity
GO:0004435 0.01155 3.65269 2 6 27 phosphatidylinositol phospholipase C activity
GO:0031402 0.01173 5.67717 1 4 13 sodium ion binding
GO:0015298 0.01180 3.19725 3 7 35 solute:cation antiporter activity
GO:0099516 0.01205 2.51005 4 10 61 ion antiporter activity
GO:0004012 0.01250 4.25967 1 5 20 phospholipid-translocating ATPase activity
GO:0043395 0.01250 4.25967 1 5 20 heparan sulfate proteoglycan binding
GO:0072341 0.01314 2.34746 5 11 71 modified amino acid binding
GO:0004725 0.01337 2.08604 7 14 100 protein tyrosine phosphatase activity
GO:0042578 0.01338 1.51913 26 38 360 phosphoric ester hydrolase activity
GO:0051020 0.01386 1.38580 45 60 619 GTPase binding
GO:0031267 0.01392 1.42092 38 52 524 small GTPase binding
GO:0005319 0.01393 1.87693 10 18 141 lipid transporter activity
GO:0019955 0.01451 2.06193 7 14 101 cytokine binding
GO:0004177 0.01482 2.76584 3 8 45 aminopeptidase activity
GO:0004359 0.01511 25.51943 0 2 3 glutaminase activity
GO:0004937 0.01511 25.51943 0 2 3 alpha1-adrenergic receptor activity
GO:0005111 0.01511 25.51943 0 2 3 type 2 fibroblast growth factor receptor binding
GO:0030172 0.01511 25.51943 0 2 3 troponin C binding
GO:0031749 0.01511 25.51943 0 2 3 D2 dopamine receptor binding
GO:0035373 0.01511 25.51943 0 2 3 chondroitin sulfate proteoglycan binding
GO:0035663 0.01511 25.51943 0 2 3 Toll-like receptor 2 binding
GO:0086056 0.01511 25.51943 0 2 3 voltage-gated calcium channel activity involved in AV node cell action potential
GO:0005523 0.01549 5.10913 1 4 14 tropomyosin binding
GO:0016918 0.01549 5.10913 1 4 14 retinal binding
GO:0019841 0.01549 5.10913 1 4 14 retinol binding
GO:0047555 0.01549 5.10913 1 4 14 3',5'-cyclic-GMP phosphodiesterase activity
GO:0070008 0.01549 5.10913 1 4 14 serine-type exopeptidase activity
GO:0043169 0.01705 1.15430 306 338 4207 cation binding
GO:0098631 0.01832 2.88730 3 7 38 cell adhesion mediator activity
GO:0017016 0.01857 1.40382 37 50 509 Ras GTPase binding
GO:0004629 0.01924 3.19551 2 6 30 phospholipase C activity
GO:0016772 0.01979 1.28147 73 90 999 transferase activity, transferring phosphorus-containing groups
GO:0016722 0.01992 4.64438 1 4 15 oxidoreductase activity, oxidizing metal ions
GO:0030676 0.01992 4.64438 1 4 15 Rac guanyl-nucleotide exchange factor activity
GO:0097153 0.01992 4.64438 1 4 15 cysteine-type endopeptidase activity involved in apoptotic process
GO:0005070 0.02112 2.39877 4 9 57 SH3/SH2 adaptor activity
GO:0030165 0.02154 2.07622 6 12 86 PDZ domain binding
GO:0005488 0.02216 1.19254 1076 1101 14790 binding
GO:1990782 0.02241 2.24500 5 10 67 protein tyrosine kinase binding
GO:0019865 0.02263 3.54906 2 5 23 immunoglobulin binding
GO:0004716 0.02317 6.38294 1 3 9 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0008510 0.02317 6.38294 1 3 9 sodium:bicarbonate symporter activity
GO:0032393 0.02317 6.38294 1 3 9 MHC class I receptor activity
GO:0033691 0.02317 6.38294 1 3 9 sialic acid binding
GO:0045499 0.02317 6.38294 1 3 9 chemorepellent activity
GO:0070700 0.02317 6.38294 1 3 9 BMP receptor binding
GO:0005245 0.02387 2.71198 3 7 40 voltage-gated calcium channel activity
GO:0005215 0.02443 1.22809 102 121 1399 transporter activity
GO:0016641 0.02507 4.25708 1 4 16 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
GO:0022821 0.02507 4.25708 1 4 16 potassium ion antiporter activity
GO:0046527 0.02507 4.25708 1 4 16 glucosyltransferase activity
GO:0050664 0.02507 4.25708 1 4 16 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
GO:0048306 0.02593 2.30254 4 9 59 calcium-dependent protein binding
GO:0005501 0.02595 2.94933 2 6 32 retinoid binding
GO:0004114 0.02692 3.36206 2 5 24 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0036094 0.02803 1.17227 176 199 2413 small molecule binding
GO:0001847 0.02876 12.75892 0 2 4 opsonin receptor activity
GO:0004477 0.02876 12.75892 0 2 4 methenyltetrahydrofolate cyclohydrolase activity
GO:0004488 0.02876 12.75892 0 2 4 methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0004583 0.02876 12.75892 0 2 4 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
GO:0004771 0.02876 12.75892 0 2 4 sterol esterase activity
GO:0038064 0.02876 12.75892 0 2 4 collagen receptor activity
GO:0048763 0.02876 12.75892 0 2 4 calcium-induced calcium release activity
GO:0002020 0.03031 1.76700 10 16 132 protease binding
GO:0003951 0.03094 3.92937 1 4 17 NAD+ kinase activity
GO:0046625 0.03094 3.92937 1 4 17 sphingolipid binding
GO:0016176 0.03133 5.47075 1 3 10 superoxide-generating NADPH oxidase activator activity
GO:0035325 0.03133 5.47075 1 3 10 Toll-like receptor binding
GO:0039706 0.03133 5.47075 1 3 10 co-receptor binding
GO:0071723 0.03133 5.47075 1 3 10 lipopeptide binding
GO:0004112 0.03170 3.19376 2 5 25 cyclic-nucleotide phosphodiesterase activity
GO:0004896 0.03197 1.94421 7 12 91 cytokine receptor activity
GO:0016298 0.03357 1.77873 9 15 123 lipase activity
GO:0019840 0.03407 2.73832 2 6 34 isoprenoid binding
GO:0016303 0.03420 2.48551 3 7 43 1-phosphatidylinositol-3-kinase activity
GO:0030674 0.03488 1.64529 12 19 167 protein binding, bridging
GO:0015081 0.03678 1.65922 11 18 157 sodium ion transmembrane transporter activity
GO:0004181 0.03697 3.04149 2 5 26 metallocarboxypeptidase activity
GO:0001972 0.03756 3.64847 1 4 18 retinoic acid binding
GO:0001784 0.03868 2.64373 3 6 35 phosphotyrosine residue binding
GO:0015297 0.04069 1.92785 6 11 84 antiporter activity
GO:0004143 0.04080 4.78661 1 3 11 diacylglycerol kinase activity
GO:0004875 0.04080 4.78661 1 3 11 complement receptor activity
GO:0017154 0.04080 4.78661 1 3 11 semaphorin receptor activity
GO:0019864 0.04080 4.78661 1 3 11 IgG binding
GO:0031996 0.04080 4.78661 1 3 11 thioesterase binding
GO:0048407 0.04080 4.78661 1 3 11 platelet-derived growth factor binding
GO:0030295 0.04126 1.99858 5 10 74 protein kinase activator activity
GO:0004860 0.04260 1.85005 7 12 95 protein kinase inhibitor activity
GO:0003785 0.04275 2.90306 2 5 27 actin monomer binding
GO:0008066 0.04275 2.90306 2 5 27 glutamate receptor activity
GO:0016788 0.04281 1.27304 53 66 734 hydrolase activity, acting on ester bonds
GO:0005230 0.04463 1.96771 5 10 75 extracellular ligand-gated ion channel activity
GO:0043178 0.04463 1.96771 5 10 75 alcohol binding
GO:0005234 0.04491 3.40503 1 4 19 extracellularly glutamate-gated ion channel activity
GO:0015349 0.04565 8.50542 0 2 5 thyroid hormone transmembrane transporter activity
GO:0019863 0.04565 8.50542 0 2 5 IgE binding
GO:0023029 0.04565 8.50542 0 2 5 MHC class Ib protein binding
GO:0030492 0.04565 8.50542 0 2 5 hemoglobin binding
GO:0035727 0.04565 8.50542 0 2 5 lysophosphatidic acid binding
GO:0070915 0.04565 8.50542 0 2 5 lysophosphatidic acid receptor activity
GO:0086007 0.04565 8.50542 0 2 5 voltage-gated calcium channel activity involved in cardiac muscle cell action potential
GO:0098639 0.04565 8.50542 0 2 5 collagen binding involved in cell-matrix adhesion
GO:0061134 0.04644 1.51203 16 23 218 peptidase regulator activity
GO:0001540 0.04860 2.13054 4 8 56 amyloid-beta binding
GO:0016504 0.04904 2.47286 3 6 37 peptidase activator activity
GO:0005217 0.04904 2.77666 2 5 28 intracellular ligand-gated ion channel activity
GO:0017076 0.04930 1.16631 136 154 1866 purine nucleotide binding